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MD Pharmacology, MBBS
Last updated
17 Nov 2024 | 01:11 AM (IST)

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Plepine 1000mg/500mg Injection

Prescription Required

Product introduction

Plepine 1000mg/500mg Injection is a combination of two antibiotics. It is prescribed to treat various types of bacterial infections. It fights against the infection by preventing the growth of microorganisms.

Plepine 1000mg/500mg Injection should only be administered under the supervision of a healthcare professional. Do not miss any scheduled appointments for taking this medicine. The course of the medicine should be completed even if you feel better.

The common side effects of this medicine are nausea, vomiting, diarrhea, rashes, etc. You may also experience injection site redness, swelling, and pain that goes away with time. If any of the side effects get aggravated, you must consult your doctor immediately. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must seek immediate medical help.

Before taking this medicine, you should tell your doctor if you are taking any medicines for any health condition. Pregnant or breastfeeding women should also consult with their doctor before taking it. Avoid drinking alcohol as it can cause excessive drowsiness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy.

Uses of Plepine Injection

Benefits of Plepine Injection

In Bacterial infections

Plepine 1000mg/500mg Injection works by killing bacteria which can cause bacterial infections. It is used to treat many different types of bacterial infections. It is given by a doctor or nurse into a vein and should not be self-administered. Plepine 1000mg/500mg Injection usually makes you feel better very quickly but you should continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and do not become resistant.

Side effects of Plepine Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Plepine

  • Diarrhea
  • Injection site reaction
  • Injection site pain
  • Injection site inflammation
  • Allergic reaction
  • Rash

How to use Plepine Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Plepine Injection works

Plepine 1000mg/500mg Injection is a combination of two medicines: Cefepime and Sulbactam. Cefepime is an antibiotic. It works by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria in the human body. Sulbactam is a beta-lactamase inhibitor which blocks the action of enzymes produced by bacteria to inactivate cefepime. Addition of Sulbactam reduces resistance and enhances the activity of Cefepime against bacteria.

Safety advice

Alcohol
UNSAFE
Plepine 1000mg/500mg Injection may cause excessive drowsiness with alcohol.
Pregnancy
SAFE IF PRESCRIBED
Plepine 1000mg/500mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
SAFE IF PRESCRIBED
Plepine 1000mg/500mg Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
Plepine 1000mg/500mg Injection may cause side effects which could affect your ability to drive.
Kidney
CAUTION
Plepine 1000mg/500mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Plepine 1000mg/500mg Injection may be needed. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Plepine 1000mg/500mg Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Plepine 1000mg/500mg Injection may not be needed in these patients. Please consult your doctor.

What if you forget to take Plepine Injection?

If you miss a dose of Plepine 1000mg/500mg Injection, please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Plepine 1000mg/500mg Injection
₹329/Injection
₹167/injection
50% cheaper
Zardpime S Injection
Vibcare Pharma Pvt Ltd
₹325/injection
2% cheaper
Wopime-S Injection
Wohltat Lifesciences
₹412/injection
24% costlier
₹495/injection
49% costlier
₹599/injection
80% costlier

Quick tips

  • You have been prescribed this combination medicine to treat bacterial infections, even if they have developed resistance.
  • Finish the full course of treatment even if you feel better. Stopping it early may make the infection to come back and harder to treat.
  • Talk to your doctor if you notice bloody stools or develop abdominal cramps.
  • Inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking it.

Fact Box

Habit Forming
No
Therapeutic Class
ANTI INFECTIVES

Patient concerns

arrow
Scar on face due to bacterial infections
Dr. Atul Jain
Dermatology
Pic is not clear, plz visit for proper opinion
I have a history of recurring yeast and bacterial vaginosis infections.
Dr. Sonu Balhara Ahlawat
Obstetrics and Gynaecology
Tab metrogyl 500 mg twice a day x 5 days and tab fluconazole 150 mg three doses alternate days
arrow

FAQs

How long does Plepine 1000mg/500mg Injection takes to work?

Usually, Plepine 1000mg/500mg Injection starts working soon after taking it. However, it may take some days to kill all the harmful bacteria and make you feel better.

What if I don't get better after using Plepine 1000mg/500mg Injection?

Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.

Can I stop taking Plepine 1000mg/500mg Injection when I feel better?

No, do not stop taking Plepine 1000mg/500mg Injection and complete the full course of treatment even if you feel better. Your symptoms may improve before the infection is completely cured.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Venus Remedies Limited. Cefepime + Sulbactam. [Accessed 09 Apr. 2019] (online) Available from:External Link
  2. Cefepime. Deerfield, Illinois: Baxter Healthcare Corporation; 1996. [Accessed 10 Apr. 2019] (online) Available from:External Link

Marketer details

Name: Plenum Biotech Pvt. Ltd.
Address: Plot Number 463, Industrial Area Phase 1, Panchkula – 134113
Country of origin: India

329
Inclusive of all taxes
MRP332.5  1% OFF
1.0 Injection in 1 vial
SOLD OUT
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