Polypril 10mg Tablet is widely used to treat high blood pressure and heart failure and may even be prescribed after a heart attack. It also lowers the chances of having a heart attack or stroke.

Polypril 10mg Tablet may be prescribed either alone or in combination with other medicines. It can be taken on an empty stomach or with a meal. This medicine should preferably be taken at the same time each day to get the maximum benefit. It is important to continue taking it regularly even if you feel well or even if your blood pressure is controlled.

Most people with high blood pressure do not feel any symptoms, but if you stop taking this medicine, your condition could get worse. This is a widely used medicine and is considered safe for long-term use. Making some changes in your lifestyle will also help lower your blood pressure. These may include regular exercise, losing weight, not smoking, reducing alcohol intake, and reducing the amount of salt in your diet as advised by your doctor.

The most common side effects of this medicine include feeling dry cough, headache, and fatigue. Most of these are temporary and resolve with time. Talk to your doctor if any of the side effects bother you or do not go away.

Before taking this medicine, let your doctor know if you have any kidney or liver problems. Pregnant or breastfeeding mothers should also consult their doctor before taking it. Your doctor may check your kidney function, blood pressure, and potassium levels in your blood at regular intervals while you are taking this medicine.

Uses of Polypril Tablet

Hypertension (high blood pressure)
Prevention of heart attack and stroke
Heart failure

Side effects of Polypril Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Polypril

Dry cough
Headache
Fatigue

How to use Polypril Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Polypril 10mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Polypril Tablet works

Polypril 10mg Tablet is an angiotensin converting enzyme (ACE) inhibitor. It works by reducing stress on the heart and relaxing blood vessel so that blood flows more smoothly and the heart can pump blood more efficiently.

Safety advice

Alcohol

UNSAFE

Polypril 10mg Tablet may cause excessive drowsiness with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Polypril 10mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Polypril 10mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Polypril 10mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Polypril 10mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Polypril 10mg Tablet may be needed. Please consult your doctor.
Regular monitoring of blood pressure is recommended for dose adjustment.

Liver

CAUTION

Polypril 10mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Polypril 10mg Tablet may be needed. Please consult your doctor.
Inform your doctor if you develop any signs and symptoms of jaundice while taking this medicine.

What if you forget to take Polypril Tablet?

If you miss a dose of Polypril 10mg Tablet, skip it and continue with your normal schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Polypril 10mg Tablet

₹13.0/Tablet

Ramipres 10 Tablet

Cipla Ltd

₹23.6/tablet

82% costlier

Cardace 10 Tablet

Sanofi India Ltd

₹29.4/tablet

126% costlier

Ramistar 10 Tablet

Lupin Ltd

₹29.8/tablet

129% costlier

Hopace 10 Tablet

Micro Labs Ltd

₹19.1/tablet

47% costlier

Cardace 10 Tablet

Sanofi India Ltd

₹18/tablet

38% costlier

View all substitutes

Quick tips

Polypril 10mg Tablet can make you feel dizzy for the first few days, so rise slowly if you have been sitting or lying down. You can also prefer taking it at bedtime to avoid dizziness throughout the day.
Let your doctor know about any cough, or throat irritation that does not go away.
It may increase the level of potassium in blood. Avoid taking potassium supplements and potassium-rich foods such as banana and broccoli.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
You have been prescribed Polypril 10mg Tablet to improve blood pressure.
Lowering blood pressure reduces the chance of future heart attack & strokes.
It may also be used to treat chronic (long-standing) heart failure.
It protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney diseases.
Polypril 10mg Tablet can make you feel dizzy for the first few days, so rise slowly if you have been sitting or lying down. You can also prefer taking it at bedtime to avoid dizziness throughout the day.
Let your doctor know about any cough, or throat irritation that does not go away.
It may increase the level of potassium in blood. Avoid taking potassium supplements and potassium-rich foods such as banana and broccoli.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Fact Box

Chemical Class

Dipeptides (Carboxylic acids derivatives)

Habit Forming

Therapeutic Class

CARDIAC

Action Class

Angiotensin-Converting Enzyme (ACE) Inhibitors

Interaction with drugs

Taking Polypril with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Spironolactone (Oral Route) Severe

Concurrent use may cause high blood potassium levels. Do not consume Ramipril with Spironolactone in case of kidney disorders. If concurrent use is essential, your doctor may clos... More

Trimethoprim (Oral Route) Severe

Concurrent use may increase the risk of high blood potassium levels and/or sudden death. Do not consume Ramipril with Trimethoprim. If concurrent use is essential, please consult ... More

Co-trimoxazole (Oral Route) Severe

Concurrent use may increase the risk of high blood potassium levels and/or sudden death. Do not consume Ramipril with Co-trimoxazole. If concurrent use is essential, please consul... More

Eplerenone (Oral Route) Severe

Concurrent use may cause high blood potassium levels. If concurrent use is essential, watch out for symptoms such as muscle weakness, fatigue, cramps, nausea, vomiting, tingling, ... More

Tacrolimus (Oral Route) Severe

Concurrent use may increase the risk of high blood potassium levels and/or damage to the kidneys. If concurrent use is essential, your doctor may monitor your kidney function and ... More

View all drug interactions

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Diabetes with heart paining and high BLood pressure

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FAQs

I have been diagnosed with heart failure and the doctor has prescribed me Polypril 10mg Tablet. Why?

Polypril 10mg Tablet belongs to the angiotensin-converting enzyme (ACE) inhibitor group of drugs. It relaxes and widens the blood vessels, making it easier for the blood to pass through the vessels. As a result of this, the heart does not have to work more to push the blood. Since the workload on the heart is reduced, it is beneficial in heart failure. Additionally, it is also used to lower blood pressure and prevent stroke.

Can Polypril 10mg Tablet increase potassium levels? If yes, what should be done?

Polypril 10mg Tablet may increase potassium levels in the blood, especially if you have uncontrolled diabetes mellitus, kidney problems, and dehydration. Potassium levels may also increase in patients using potassium salts or medicines which increase potassium levels or are aged more than 70 years of age. If you have any of these conditions and are using Polypril 10mg Tablet, you need to be careful and get regular blood tests done to monitor potassium levels.

When can I expect my blood pressure to be normal after starting Polypril 10mg Tablet?

Polypril 10mg Tablet takes a few hours to reduce high blood pressure but since there are no symptoms, you will not notice any difference. It takes a few weeks for the blood pressure to get fully controlled. Do not stop taking the medicine. Keep taking it even if you feel better or if your blood pressure is normalized.

Ever since I started taking Polypril 10mg Tablet, I noticed that I have developed a dry cough which is very irritating and is not relieved by any medicine. Why is it?

Polypril 10mg Tablet commonly is responsible for dry cough which can be persistent and is not relieved by any medicine. Talk to your doctor if it bothers you or you have trouble sleeping, as another medicine may be better. Even if you stop taking Polypril 10mg Tablet, the cough may take a few days to a month to go away.

I accidentally took a 25 mg Polypril 10mg Tablet tablet instead of one 5 mg. Will it have any harmful effects?

Yes, you may feel lightheaded, dizzy, your pulse may become slow and you may even faint. You should take the help of a relative or friend for an emergency or seek immediate medical support.

Will there be any problem if I am taking Polypril 10mg Tablet and I have surgery scheduled in a week?

Inform your doctor that you are taking Polypril 10mg Tablet. Polypril 10mg Tablet can reduce your blood pressure when it is used with a general anesthetic. Your doctor may advise you to stop taking it 24 hours before surgery.

Can Polypril 10mg Tablet affect my fertility?

There is no evidence that Polypril 10mg Tablet has any effect on fertility in both men and women. However, if you are planning to get pregnant, talk to your doctor first because Polypril 10mg Tablet is not recommended in pregnancy.

I have diabetes. Does Polypril 10mg Tablet have any effect on blood sugar levels?

Yes, Polypril 10mg Tablet may have some effect on antidiabetic medicines and insulin and may lower your blood sugar levels. Therefore, you need to check your blood sugar levels regularly.

I have been using Polypril 10mg Tablet for blood pressure for some time, but now I have noticed that I often have a sore throat along with fever. I want to stop Polypril 10mg Tablet and see if this goes, can I stop Polypril 10mg Tablet?

No, you should not stop Polypril 10mg Tablet suddenly as this may cause a sudden increase in your blood pressure which may be harmful to you. In addition to this, Polypril 10mg Tablet can very rarely decrease your white blood cell count which is important to fight infections in your body. Consult your doctor and get a blood test done. If your white cell count is decreased, it could be due to Polypril 10mg Tablet. Ask your doctor for alternative medicine for blood pressure. You can continue taking Polypril 10mg Tablet if your investigations are normal.

Is it safe to take Polypril 10mg Tablet for a long time?

Yes, Polypril 10mg Tablet is safe and works best if taken for a long time. But, taking Polypril 10mg Tablet for a long time can sometimes affect the working of your kidneys. To keep track of this, your doctor will get regular blood tests done and check how well your kidneys are working.

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References

Hilal-Dandan R. Renin and Angiotensin. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 733.
Pfeffer MA, Opie LH. Inhibitors of the Renin-Angiotensin-Aldosterone System. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 143-44.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1195-96.
Ramipril. New York, New York: Pfizer, Inc.; 1991 [revised Sep. 2013]. [Accessed 19 Mar. 2019] (online) Available from:
Ramipril. South Ruislip, UK: Aurobindo Pharma - Milpharm Ltd.; 2011 [revised 19 Mar. 2018]. [Accessed 19 Jun. 2019] (online) Available from:
National Health Service. Ramipril; 2018. [Accessed 19 Jun. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:
CiplaMed. Ramipril [Prescribing Information]. [Accessed 25 Jul. 2023] (online) Available from:

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Address: 1003 Kirti Shikhar Building, Janakpuri, Delhi - 110058, Distt Centre

Country of origin: India

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