Posalup Injection
Prescription Required
Product introduction
Posalup Injection belongs to a group of medicines called antifungals. It works by stopping the growth of fungus and is used to treat fungal infections. It kills fungi by destroying the fungal cell membrane.
Do not self-administer this medicine. Your doctor or nurse will teach you the correct way of injecting it. To get the most benefit, take this medicine at evenly spaced times and continue using it until your prescription is finished, even if your symptoms disappear after a few days. If you stop treatment too early, the infection may return and if you miss doses you can increase your risk of infections that are resistant to further treatment.
The most common side effects of this medicine include diarrhea, nausea, fever, vomiting, headache, coughing, and hypokalemia. These are not usually serious, but you should call your doctor if you think you might have a severe allergic reaction and signs of liver problems such as yellowing of eyes, dark urine, and stomach problems. Get emergency help if this happens.
Do not take it if you are pregnant or could become pregnant unless your doctor has told you to. Talk to your doctor before taking it if you have ever had heart failure, kidney problems, or liver problems such as yellow skin (jaundice). This medicine may not be suitable for you. If your course of treatment is for more than a month, your doctor may want to check your liver, and potassium level by testing your blood. This medicine may make you dizzy or have blurred vision so do not drive or operate machines until it is safe.
Do not self-administer this medicine. Your doctor or nurse will teach you the correct way of injecting it. To get the most benefit, take this medicine at evenly spaced times and continue using it until your prescription is finished, even if your symptoms disappear after a few days. If you stop treatment too early, the infection may return and if you miss doses you can increase your risk of infections that are resistant to further treatment.
The most common side effects of this medicine include diarrhea, nausea, fever, vomiting, headache, coughing, and hypokalemia. These are not usually serious, but you should call your doctor if you think you might have a severe allergic reaction and signs of liver problems such as yellowing of eyes, dark urine, and stomach problems. Get emergency help if this happens.
Do not take it if you are pregnant or could become pregnant unless your doctor has told you to. Talk to your doctor before taking it if you have ever had heart failure, kidney problems, or liver problems such as yellow skin (jaundice). This medicine may not be suitable for you. If your course of treatment is for more than a month, your doctor may want to check your liver, and potassium level by testing your blood. This medicine may make you dizzy or have blurred vision so do not drive or operate machines until it is safe.
Uses of Posalup Injection
- Severe fungal infections
Benefits of Posalup Injection
In Severe fungal infections
Posalup Injection is an antifungal medicine. It works by killing and stopping the growth of fungus that is causing the infection. It helps treat severe infections in severely immunocompromised patients, cancer patients, and those undergoing blood transfusion. It is given as an injection by your doctor or healthcare provider and should not be self-administered.
The dose and duration of treatment will depend on what you are being treated for. Make sure you complete the full course of treatment. This will ensure that the infection is completely cured and prevent it from returning.
The dose and duration of treatment will depend on what you are being treated for. Make sure you complete the full course of treatment. This will ensure that the infection is completely cured and prevent it from returning.
Side effects of Posalup Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Posalup
- Increased calcium level in blood
- Urinary tract infection
- Headache
- Rash
- Decreased appetite
- Decreased white blood cell count (neutrophils)
- Dizziness
- Electrolyte imbalance
- Fatigue
- Fever
- Decreased potassium level in blood
- Increased liver enzymes
- Insomnia (difficulty in sleeping)
- Itching
- Sleepiness
- Taste change
- Weakness
- Decreased magnesium level in blood
- Paresthesia (tingling or pricking sensation)
- High blood pressure
- Anorectal discomfort
- Increased glucose level in blood
- Hypoglycemia (low blood glucose level)
- Hypotension (low blood pressure)
- Nausea
- Diarrhea
- Anemia (low number of red blood cells)
- Low blood platelets
- Petechiae (red or purple spot caused by bleeding into the skin)
- Vomiting
- Cough
- Abdominal pain
- Constipation
- Indigestion
- Nosebleeds
- Rigors
- Swelling of legs
- Breathlessness
How to use Posalup Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Posalup Injection works
Posalup Injection is an antifungal medication. It kills fungi by destroying the fungal cell membrane. This treats your infection.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Posalup Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Posalup Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Posalup Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Posalup Injection may cause side effects which could affect your ability to drive.
As you may feel dizzy, sleepy, or have blurred vision while taking Posalup Injection, which may affect your ability to drive.
As you may feel dizzy, sleepy, or have blurred vision while taking Posalup Injection, which may affect your ability to drive.
Kidney
CAUTION
Posalup Injection should be used with caution in patients with kidney disease. Dose adjustment of Posalup Injection may be needed. Please consult your doctor.
Regular monitoring of kidney function tests is advised while taking this medicine. Use of Posalup Injection is not recommended in patients with moderate to severe kidney disease.
Regular monitoring of kidney function tests is advised while taking this medicine. Use of Posalup Injection is not recommended in patients with moderate to severe kidney disease.
Liver
SAFE IF PRESCRIBED
Posalup Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Posalup Injection may not be needed in these patients. Please consult your doctor.
What if you forget to take Posalup Injection?
If you miss a dose of Posalup Injection, consult your doctor.
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Quick tips
- Your doctor has prescribed Posalup Injection to cure your infection and improve symptoms.
- Do not skip any doses and finish the full course of treatment even if you feel better.
- It is given as an injection under the supervision of a healthcare professional.
- Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
- Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Fact Box
Chemical Class
Azoles {Triazoles}
Habit Forming
No
Action Class
Fungal ergosterol synthesis inhibitor
Interaction with drugs
Taking Posalup with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concurrent use may cause serious damage to muscles. Posaconazole may raise blood levels of Lovastatin.
Do not consume Lovastatin with Posaconazole. If Posaconazole is essential, yo
Concurrent use may cause muscle damage. Posaconazole may raise blood levels of Simvastatin.
Do not consume Simvastatin with Posaconazole. If Posaconazole is essential, your doctor
Concurrent use may cause muscle damage.
Do not consume Atorvastatin with Posaconazole. If concurrent use is essential, watch out for symptoms such as muscle pains or weakness and
Concomitant use may affect heart rhythm and can be fatal.
Do not consume Pimozide with Posaconazole.
Concurrent use may cause life-threatening disturbances in the heart rhythm. Posaconazole may raise blood levels of Ranolazine.
Do not consume Ranolazine with Posaconazole. If concu
Patient concerns
FAQs
What is Posalup Injection and what is it used for?
Posalup Injection belongs to a class of medicines known as antifungal medicines. It is used to treat serious infections caused by various types of fungi such as Aspergillus and Candida, in patients who are at high risk of developing these infections. Posalup Injection is majorly prescribed to severely immunocompromised patients in cases of cancer or those undergoing blood transfusion or chemotherapy.
How is Posalup Injection administered?
Posalup Injection is administered under the supervision of a trained healthcare professional or a doctor and should not be self administered. The dose will depend on the condition you are being treated for and will be decided by your doctor. Follow your doctor’s instructions carefully to get maximum benefit from Posalup Injection.
Is Posalup Injection effective?
Posalup Injection is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using Posalup Injection too early, the symptoms may return or worsen.
What are the side effects of Posalup Injection?
Some of the common side effects of Posalup Injection are cough, headache, nausea, and vomiting. However, these are usually not bothersome and usually resolve on their own. Please consult your doctor if any of thes side effects worry you or persist for a longer duration.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Bennett JE. Antifungal Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1581-82.
- Sheppard D, Lampiris HW. Antifungal Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 841.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1135-36.
- Posaconazole. White House Station, New Jersey: Merck & Co.; 2015. [Accessed 29 Mar. 2019] (online) Available from:
- Posaconazole. Hoddesdon, Hertfordshire: Merck Sharp & Dohme Limited; 2005 [revised 6 Jul. 2018]. [Accessed 29 Mar. 2019] (online) Available from:
Marketer details
Name: Lupin Ltd
Address: 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India
Country of origin: India
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