Pranosol 1mg Injection is a medicine used to treat various heart disorders such as abnormal heart rhythm (arrhythmia) and very high blood pressure (hypertensive emergency) as it may be life-threatening and needs immediate medical help. Pranosol 1mg Injection is also used to prevent angina (heart-related chest pain).
Pranosol 1mg Injection is generally administered by a doctor or a nurse. It should not be self-administered at home. The dose and duration will depend on the severity of your condition and how you respond to the medicine. Keep taking the injection for as long as the doctor has prescribed even if you feel well. If you stop taking it suddenly, your condition may worsen.
The most common side effects are tiredness, weakness, Raynaud phenomenon (cold fingers and toes), insomnia, and breathlessness. You may also experience nausea, vomiting, and diarrhea. Talk to your doctor if the side effects bother you or will not go away. Most are short-lived and improve as your body gets used to the medicine.
You should not use this medicine if you have asthma, very slow or uneven heartbeats, or a serious heart condition, including heart failure. Talk to your doctor before taking it if you have kidney or liver problems or chronic obstructive pulmonary disease (COPD). In terms of lifestyle, alcohol may affect the way this medicine works and should be avoided. You should not drive if this medicine makes you feel dizzy. Ask your doctor whether it is safe to take this medicine if you are pregnant or breastfeeding.
In Prevention of Angina (heart-related chest pain)
Pranosol 1mg Injection relaxes the blood vessels so that blood can flow more easily around your body and makes sure that your heart is getting a good supply of oxygen. This makes it less likely that you will suffer chest pain caused by angina. This medicine can help increase your ability to exercise and go about your daily life more easily by reducing the frequency of angina attacks. You should take it regularly and as long as it is prescribed for it to work effectively.
In Treatment of Hypertensive emergency
Pranosol 1mg Injection blocks the effect of some chemicals on your heart and blood vessels. This slows down the heart rate and helps the heart beat with less force thereby lowering your blood pressure. This medicine is injected into a vein under the supervision of a doctor. It is used for immediate reduction of very high blood pressure (hypertensive emergency). A controlled blood pressure reduces the risk of having a heart attack, stroke, or kidney problems.
In Prevention of migraine
Pranosol 1mg Injection helps improve the flow of blood in your brain and prevents abnormal activity of muscles that triggers migraines. It is a very effective medicine for preventing migraine attacks, however, it does not treat an attack that has already started. By preventing and reducing the frequency of migraine attacks, the medicine can help you carry out your daily activities and improve your quality of life.
In Treatment of Pheochromocytoma
While carrying out surgery for the removal of pheochromocytoma, there is a risk of abnormally high blood pressure. Pranosol 1mg Injection blocks the effect of some chemicals on your heart and blood vessels. This slows down the heart rate and helps the heartbeat with less force thereby lowering your blood pressure. It is used for the immediate reduction of very high blood pressure (hypertensive emergency). Controlled blood pressure reduces the risk of having a heart attack, stroke, or kidney problems.
Side effects of Pranosol Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Pranosol
Slow heart rate
Fatigue
Sleep disturbance
Nightmares
Cold extremities
How to use Pranosol Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Pranosol Injection works
Pranosol 1mg Injection contains Propranolol, a beta blocker. It works by affecting the body’s response to nerve impulses, especially in the heart. It slows down your heart rate and makes it easier for the heart to pump blood around the body. This prevents arrhythmias. It also widens the blood vessels in the body for better blood flow, thereby preventing angina.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Pranosol 1mg Injection.
Pregnancy
CONSULT YOUR DOCTOR
Pranosol 1mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Pranosol 1mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Pranosol 1mg Injection may cause side effects which could affect your ability to drive.
Kidney
CAUTION
Pranosol 1mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment of Pranosol 1mg Injection may be needed. Please consult your doctor.
Liver
CAUTION
Pranosol 1mg Injection should be used with caution in patients with liver disease. Dose adjustment of Pranosol 1mg Injection may be needed. Please consult your doctor. Regular monitoring of blood pressure is advisable for dose adjustment.
What if you forget to take Pranosol Injection?
If you miss a dose of Pranosol 1mg Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
It is not the first-choice treatment for high blood pressure according to the latest guidelines.
It may hide the symptoms of low blood sugar if you have diabetes. Monitor blood sugar levels regularly.
To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
Use caution while driving or doing anything that requires concentration as Pranosol 1mg Injection can cause dizziness and sleepiness.
Inform your doctor if you notice increased swelling around your legs or ankles, sudden weight gain or sudden shortness of breath as these may be symptoms of heart failure.
Do not stop taking the medication suddenly without talking to your doctor.
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My doctor has prescribed Pranosol 1mg Injection even though my blood pressure is within normal limits. Is it because of the chest pain that I complained of?
Yes, it is possible that your doctor prescribed Pranosol 1mg Injection for chest pain (angina). Pranosol 1mg Injection is a beta-blocker that is used to lower high blood pressure, prevent angina, treat or prevent heart attacks or reduce your risk of heart problems following a heart attack. Pranosol 1mg Injection is also used to treat irregularities in the heartbeat, including those caused by anxiety, essential tremor (shaking of the head, chin and hands). It also prevents migraine headaches, overactive thyroid (thyrotoxicosis and hyperthyroidism), and bleeding in the food pipe caused by high blood pressure.
When can I expect relief in my symptoms after starting Pranosol 1mg Injection for high blood pressure?
Pranosol 1mg Injection usually starts working within a few hours of taking it. However, it may take up to a week to see the full benefits of the symptoms of high blood pressure or heart conditions. You may not notice any difference, but that does not mean it is not working. However, keep taking this medicine as prescribed by your doctor because you will still be getting its full benefits.
Can Pranosol 1mg Injection be used in asthmatics?
No, Pranosol 1mg Injection cannot be used in asthmatics. This is because using Pranosol 1mg Injection in asthma patients can cause breathing problems, which may trigger an asthma attack. Always inform your doctor if you have or ever had asthma or any episodes of difficulty breathing, before starting treatment with Pranosol 1mg Injection.
What if I forget to take a dose of Pranosol 1mg Injection?
If you forget a dose of Pranosol 1mg Injection, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose at the prescribed time. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.
Can I stop taking Pranosol 1mg Injection as my chest pain is under control?
No, you should not stop taking Pranosol 1mg Injection suddenly because that may worsen your angina or may cause a heart attack. Tell your doctor and if there is a need to stop Pranosol 1mg Injection, your doctor will reduce your dose gradually over a period of a few weeks.
Does Pranosol 1mg Injection relieve anxiety?
Yes, Pranosol 1mg Injection helps relieve the symptoms of anxiety such as irritability, restlessness, excessive worry, lack of concentration, racing or unwanted thoughts, fatigue, insomnia (lack of sleep), palpitations (irregular heart rate), or trembling. The dose and duration of taking Pranosol 1mg Injection will be suggested by your doctor, depending on whether your symptoms are a recurring problem or occur only in stressful conditions. However, Pranosol 1mg Injection is usually given for the short-term treatment of anxiety. If you have any doubts, consult your doctor.
What other lifestyle changes should I make while taking Pranosol 1mg Injection?
Lifestyle changes play a major role in keeping you healthy if you are taking Pranosol 1mg Injection. Avoid taking excess salt in your diet and find ways to reduce or manage stress in your life. Practice yoga or meditation or take up a hobby. Ensure that you have a sound sleep every night as this also helps to reduce stress levels and helps to keep your blood pressure normal. Stop smoking and alcohol consumption as this helps in lowering your blood pressure and preventing heart problems. Exercise regularly and take a balanced diet that includes whole grains, fresh fruits, vegetables, and fat-free products. Consult your doctor if you need any further guidance to get the maximum benefit of Pranosol 1mg Injection and to keep yourself healthy.
Is Pranosol 1mg Injection effective?
Pranosol 1mg Injection is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using Pranosol 1mg Injection too early, the symptoms may return or worsen.
What if I take an overdose of Pranosol 1mg Injection?
If you take an overdose of Pranosol 1mg Injection you may experience symptoms such as slow heartbeat, trembling, difficulty breathing, or dizziness. However, the response of taking too much of Pranosol 1mg Injection varies from person to person. It would be best to consult a doctor if you think you have taken more than what you are prescribed.
Is Pranosol 1mg Injection safe?
Pranosol 1mg Injection is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.
I have been on Indomethacin for several months. Will it be a problem if I start taking Pranosol 1mg Injection along with it?
Yes, Indomethacin may interfere with the working of Pranosol 1mg Injection and make it less effective. As a result, your blood pressure may increase. Speak to your doctor who will prescribe you a different medicine to control blood pressure.
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References
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Opie LH. β-Blocking Agents. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 28-29.
Benowitz NL. Antihypertensive Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 175-76.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1162-63.
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 19 Mar. 2019] (online) Available from: