Prealdonil 150mg/75mg Tablet
Prescription Required
Product introduction
Prealdonil 150mg/75mg Tablet is a medicine used to treat diabetic nerve disease. It reduces pain and protect the nerve fibers from damage. This medicine also promotes regeneration of nerve cells. It is used along with other blood sugar lowering medications in order to prevent further nerve injury.
Prealdonil 150mg/75mg Tablet should be taken on an empty stomach, but you should try to take it at the same time every day. The dose will be decided by your doctor. Do not stop taking it without asking your doctor. If you do, your blood sugar levels may increase and put you at risk of serious complications like kidney damage and blindness. This medicine is only part of a treatment program that should include a healthy diet, regular exercise, and weight reduction as advised by your doctor.
The most common side effects of this medicine include nausea, vomiting, diarrhea, drowsiness, dizziness, uncoordinated body movements, and increased liver enzymes. However, these are temporary and usually subside on their own. Please consult your doctor if these do not resolve or persist for a longer duration.
Before taking this medicine, inform your doctor if you have any kidney or liver problems or a urinary tract infection or if you are on water pills (diuretics). Pregnant or breastfeeding women should also consult their doctor before taking it. Avoid excessive alcohol intake while taking it as this may increase the risk of developing some side effects. Monitor your blood sugar levels regularly while taking this medicine.
Uses of Prealdonil Tablet
Side effects of Prealdonil Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Prealdonil
- Nausea
- Vomiting
- Diarrhea
- Drowsiness
- Dizziness
- Uncoordinated body movements
- Increased liver enzymes
How to use Prealdonil Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Prealdonil 150mg/75mg Tablet is to be taken empty stomach.
How Prealdonil Tablet works
Prealdonil 150mg/75mg Tablet is a combination of two medicines: Epalrestat and Pregabalin which treat neuropathic pain. Epalrestat is an aldose reductase inhibitor. It blocks the accumulation of sorbitol in cells, which causes diabetic nerve disease. Pregabalin is an alpha 2 delta ligand which decreases pain by modulating calcium channel activity of the nerve cells.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Prealdonil 150mg/75mg Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Prealdonil 150mg/75mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Prealdonil 150mg/75mg Tablet during breastfeeding is not available. Please consult your doctor.
Driving
UNSAFE
Prealdonil 150mg/75mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Prealdonil 150mg/75mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Prealdonil 150mg/75mg Tablet may be needed. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Prealdonil 150mg/75mg Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Prealdonil 150mg/75mg Tablet may not be needed in these patients. Please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
- Take it only as per the dose and duration prescribed by your doctor.
- Adherence to antidiabetic therapy can delay the onset of or prevent diabetic nerve disease.
- Inform your doctor if you have:
- Cut or sore on your feet that is infectious or not healing
- Burning or tingling sensation in arm or feet that hamper your routine activities
- Trouble in digestion, urination, or sexual functioning
- Dizziness
- To prevent diabetic nerve pain, wear proper footwear and examine your feet every day to detect lesions early.
- Monitor your blood sugar level regularly.
- Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
- Take it only as per the dose and duration prescribed by your doctor.
- Adherence to antidiabetic therapy can delay the onset of or prevent diabetic nerve disease.
- Inform your doctor if you have:
- Cut or sore on your feet that is infectious or not healing
- Burning or tingling sensation in arm or feet that hamper your routine activities
- Trouble in digestion, urination, or sexual functioning
- Dizziness
- To prevent diabetic nerve pain, wear proper footwear and examine your feet every day to detect lesions early.
- Monitor your blood sugar level regularly.
- Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Fact Box
Habit Forming
No
Therapeutic Class
ANTI DIABETIC
Patient concerns
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Sharma SR, Sharma N. Epalrestat, an aldose reductase inhibitor, in diabetic neuropathy: An Indian perspective. Ann Indian Acad Neurol. 2008;11(4):231-5. [Accecssed 01 Mar. 2019] (online) Available from:
- Hotta N, Akanuma Y, Kawamori R, et al. Long-term clinical effects of epalrestat, an aldose reductase inhibitor, on diabetic peripheral neuropathy: the 3-year, multicenter, comparative Aldose Reductase Inhibitor-Diabetes Complications Trial. Diabetes Care. 2006;29(7):1538-44. [Accessed 08 Apr. 2019] (online) Available from:
Marketer details
Name: Zydus Cadila
Address: Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.
Country of origin: India
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