Product introduction
Predulox 75mg/20mg Tablet is used for the treatment of neuropathic pain. It decreases pain by controlling calcium channel activity of the nerve cells. It also increases the level of chemical messengers in the brain that helps maintain mental balance and stop the movement of pain signals in the brain.
Predulox 75mg/20mg Tablet can be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor as this is habit forming medicine. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of the treatment even if you feel better. It is important not to stop taking this medicine suddenly as it may worsen your symptoms.
Some common side effects of this medicine include peripheral edema, nausea, headache, dryness of mouth, difficulty in concentration and blurred vision. It may cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine may cause weight gain and to control it, you should have a balanced diet and exercise regularly. It is important to inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts.
Before taking this medicine let your doctor know if you suffer from kidney or liver disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Side effects of Predulox Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Predulox
- Nausea
- Constipation
- Insomnia (difficulty in sleeping)
- Sleepiness
- Headache
- Dizziness
- Tiredness
- Ejaculation disorder
- Erectile dysfunction
- Uncoordinated body movements
How to use Predulox Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Predulox 75mg/20mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Predulox Tablet works
Predulox 75mg/20mg Tablet is a combination of two medicines: pregabalin and duloxetine. Pregabalin decreases neurotransmitter release, while duloxetine boosts serotonin and norepinephrine levels to modulate pain perception, working together to relieve nerve pain.
Safety advice
It is unsafe to consume alcohol with Predulox 75mg/20mg Tablet.
PregnancyCONSULT YOUR DOCTOR
Predulox 75mg/20mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feedingCONSULT YOUR DOCTOR
Predulox 75mg/20mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Predulox 75mg/20mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Predulox 75mg/20mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Predulox 75mg/20mg Tablet may be needed. Please consult your doctor.
Predulox 75mg/20mg Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
What if you forget to take Predulox Tablet?
If you miss a dose of Predulox 75mg/20mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Predulox 75mg/20mg Tablet
₹19.1/Tablet
Quick tips
- Predulox 75mg/20mg Tablet is used for treating nerve pain caused by diabetes, shingles, fibromyalgia, and spinal cord injuries.
- You may have to wait for 2 to 4 weeks before it starts working.
- It may cause dizziness during the first few weeks. Don't drive or do anything requiring concentration until you know how Predulox 75mg/20mg Tablet affects you.
- Avoid consuming alcohol when taking this medicine as it may cause excessive drowsiness and increase the risk of liver damage.
- Monitor your blood pressure regularly, especially during the first month of treatment.
- It may cause a sensation of restlessness or an inability to sit or stand still, especially when you first start taking it. Inform your doctor if this happens to you.
- Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
- Do not stop taking the medication suddenly without talking to your doctor.
Fact Box
Therapeutic Class
NEURO CNS
Patient concerns
Most of the times when I get excited or have orgasm I feel pain in my testis and around it .
Dr. Pranay Gandhi
Sexology
hi PATIENT neuropathic pain mostly. take tablet emanzen d 1 bd
Sir Plz suggest me effective pain killer with minimum side effects for back pain and arthritis, which can be taken on regular basis as and when required.
Dr. Vikas Sharma
Neurology
dpeneds on the type of pain - muscular or neuropathic; show tro nearby neuro
Neuropathic pain in leg.Unable to walk
Dr. Mehtab Baig
Orthopaedic Physiotherapy
Any test u have
charcot Anthropathy Peripheral neuropathic proble. No pain in foot
Dr. Himanshu Gupta
Dermatology
Kindly consult a neurologist / orthopaedic surgeon for this, I will not be able to help you regarding this case
Burning sensation in sole ,penile region regularly No spot at penile area but constant burning sensation at sole and penile area No relief from amoxicillin,ceprofloxin doxycyclene Period :last 14 days
Dr. Pranay Gandhi
Sexology
that may be a neuropathic pain. do u have high bp or diabetes. take tablet pregama m 1 od for 15 days
I suffered from brain stroke. How long can I use gabapentin 300 mg tablets ?
Dr. Anshul Varshney
Physician
Hello, Welcome to 1mg. I am Anshul Varshney for your help. This medicine is used to calm down the neuropathic pain. You may take it till you feel better. Later your doctor may reduce the dose and stop it.
I m suffering due to pain in left testis, so I visited pgimer Chandigarh in urology deptt. There I had gone for dopler ultrasound testis and its reports are normal Now whenever I lay down at bed I felt a smaal lump in testis,when I touchdown it, the pain radiates in whole left testis Now I m feeling pain sometimes in both tastis Is it a sign of early vericoseal Or something else Pls. Suggest
Dr. Pranay Gandhi
Sexology
it is a neuropathic pain and it won't show any abnormality in USG. i am worried about the lump u r talking about. its better if u consult a surgeon, PGIMER UROLOGY is the best place to go for examination. if they say its normal, its normal. for pain take pregaba m 1 od
What medicine cures diabetic neuropathic ill effects such as burning sensation in hands and legs and walking disability
Dr. Sanjay Bhatt
Physician
Pregastar M 75/1500
Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
Tesfaye S, Wilhelm S, Lledo A, et al. Duloxetine and pregabalin: High-dose monotherapy or their combination? The “COMBO-DN study” – a multinational, randomized, double-blind, parallel-group study in patients with diabetic peripheral neuropathic pain. Pain. 2013;154(12):2616-25. [Accessed 29 Apr. 2019] (online) Available from:
Pregabalin. Vega Baja, Puerto Rico: Pfizer Pharmaceuticals LLC; 2009. [Accessed 23 Jan. 2019] (online) Available from:
Duloxetine hydrochloride. Basingstoke, Hampshire: Eli Lilly and Company Limited; 2004 [revised 09 Nov. 2018]. [Accessed 23 Jan. 2019] (online) Available from:
Pregablin. New York, New York: Pfizer; 2004 [revised Jun 2011]. [Accessed 22 Mar. 2019] (online) Available from:
Medscape. Duloxetine. [Accessed 24 Apr. 2019] (online) Available from:
Leeford Wellness. Pregabalin & Duloxetine [Product Information]. [Accessed 16 Sep. 2024] (online) Available from:
Marketer details
Name: Icon Life Sciences
Address: Icon Life Sciences, Div. Of Mesmer Pharmaceuticals, No.202/6, Lane In.30, Phase-II, IDA, Cherlapally, Hyderabad, 500 051 AP