Pregacent NT 75mg/10mg Tablet is a combination medicine used for the treatment of neuropathic pain. This medicine decreases the pain by stopping the movement of pain signals to the brain.

Pregacent NT 75mg/10mg Tablet may be taken with or without food, preferably at bedtime. Take it at the same time each day as this helps to maintain a consistent level of medicine in the blood. Take this medicine in the dose and duration advised by your doctor. If you miss a dose of this medicine, take it as soon as you remember. Finish the complete course of treatment even if you feel better. Do not stop this medication suddenly without talking to the doctor.

Some common side effects of this medicine include constipation, nausea, vision disturbance, and excessive sweating. It may also cause dizziness and sleepiness. So, do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine may cause weight gain, and to control it, you should exercise regularly and have a balanced diet. It is important to inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts.

Before taking Pregacent NT 75mg/10mg Tablet, let your doctor know if you suffer from kidney or liver disease. Your doctor should also know about all other medicines you are taking, as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.

Uses of Pregacent NT Tablet

Treatment of Neuropathic pain

Benefits of Pregacent NT Tablet

In Treatment of Neuropathic pain

Pregacent NT 75mg/10mg Tablet helps reduce pain and its associated symptoms, such as mood changes, sleep problems, and tiredness. Taking Pregacent NT 75mg/10mg Tablet regularly will improve your physical and social functioning and overall quality of life. It takes a few weeks to work, so you need to take it regularly, even if you feel it is not doing any good.

Side effects of Pregacent NT Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pregacent NT

Dryness in mouth
Dizziness
Sleepiness
Shakiness
Altered vision
Fast heart rate
Constipation
Nausea
Increased sweating
Weight gain
Nasal congestion (stuffy nose)
Aggressive behavior

How to use Pregacent NT Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pregacent NT 75mg/10mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Pregacent NT Tablet works

Pregacent NT 75mg/10mg Tablet is a combination of two medicines: Pregabalin and Nortriptyline. Pregabalin is an alpha-2 delta ligand that decreases pain by modulating the calcium channel activity of the nerve cells. Nortriptyline is a tricyclic antidepressant that increases the levels of chemical messengers (serotonin and noradrenaline) that stop the movement of pain signals in the brain. Together, they relieve neuropathic pain (pain from damaged nerves).

Safety advice

Alcohol

UNSAFE

Pregacent NT 75mg/10mg Tablet may cause excessive drowsiness with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Pregacent NT 75mg/10mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Pregacent NT 75mg/10mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Pregacent NT 75mg/10mg Tablet may cause side effects which could affect your ability to drive.
As Pregacent NT 75mg/10mg Tablet may affect your alertness which may affect your ability to drive.

Kidney

CAUTION

Pregacent NT 75mg/10mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Pregacent NT 75mg/10mg Tablet may be needed. Please consult your doctor.

Liver

CAUTION

Pregacent NT 75mg/10mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Pregacent NT 75mg/10mg Tablet may be needed. Please consult your doctor.

What if you forget to take Pregacent NT Tablet?

If you miss a dose of Pregacent NT 75mg/10mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Pregacent NT 75mg/10mg Tablet

₹16.3/Tablet

Nortryptomer-P 10mg/75mg Tablet

Dr Reddy's Laboratories Ltd

₹30.4/tablet

87% costlier

Nortipan Tablet

Medley Pharmaceuticals

₹24.5/tablet

50% costlier

Pregaba NT 75 mg/10 mg Tablet

Torrent Pharmaceuticals Ltd

₹26/tablet

60% costlier

Nervite Tablet

Macleods Pharmaceuticals Pvt Ltd

₹23.9/tablet

47% costlier

Nurogab NT Tablet

Macleods Pharmaceuticals Pvt Ltd

₹23.6/tablet

45% costlier

View all substitutes

Quick tips

Pregacent NT 75mg/10mg Tablet is used to treat certain types of long-lasting pain caused by damage to nerves.
Inform your doctor if you are taking any other pain-relieving medicines.
Inform your doctor if you have a history of seizures.
Immediately seek medical help if you experience hallucinations, fever, sweating, shivering, fast heart rate, muscle twitching, or loss of coordination.
Along with taking Pregacent NT 75mg/10mg Tablet, your doctor might advise you to undergo physiotherapy to get relief from pain.

Fact Box

Habit Forming

Therapeutic Class

NEURO CNS

Patient concerns

Most of the times when I get excited or have orgasm I feel pain in my testis and around it .

Dr. Pranay Gandhi

Sexology

hi PATIENT neuropathic pain mostly. take tablet emanzen d 1 bd

Sir Plz suggest me effective pain killer with minimum side effects for back pain and arthritis, which can be taken on regular basis as and when required.

Dr. Vikas Sharma

Neurology

dpeneds on the type of pain - muscular or neuropathic; show tro nearby neuro

I m suffering due to pain in left testis, so I visited pgimer Chandigarh in urology deptt. There I had gone for dopler ultrasound testis and its reports are normal Now whenever I lay down at bed I felt a smaal lump in testis,when I touchdown it, the pain radiates in whole left testis Now I m feeling pain sometimes in both tastis Is it a sign of early vericoseal Or something else Pls. Suggest

Dr. Pranay Gandhi

Sexology

it is a neuropathic pain and it won't show any abnormality in USG. i am worried about the lump u r talking about. its better if u consult a surgeon, PGIMER UROLOGY is the best place to go for examination. if they say its normal, its normal. for pain take pregaba m 1 od

User feedback

What are you using Pregacent NT Tablet for?

Neuropathic p*

100%

*Neuropathic pain

How much was the improvement?

Excellent

83%

Average

17%

What were the side-effects while using Pregacent NT 75mg/10mg Tablet?

Sleepiness

25%

Weight gain

25%

Dizziness

25%

Constipation

25%

How do you take Pregacent NT Tablet?

With food

100%

Please rate Pregacent NT 75mg/10mg Tablet on price

Expensive

100%

FAQs

What is Pregacent NT 75mg/10mg Tablet used for?

Pregacent NT 75mg/10mg Tablet is a prescription medicine used to treat nerve pain (neuropathic pain). It calms the damaged or overactive nerves by acting on the brain. Thereby decreasing the pain sensation.

Can I stop taking Pregacent NT 75mg/10mg Tablet when my pain is relieved?

No, you should not stop taking Pregacent NT 75mg/10mg Tablet even if your pain is relieved. Continue to take it as advised by your doctor. If you suddenly stop taking Pregacent NT 75mg/10mg Tablet, you may experience withdrawal symptoms such as anxiety, sleeping difficulties, nausea, pain, and sweating. You may need to gradually taper the dose before you stop the medication completely.

How to manage weight gain associated with the use of Pregacent NT 75mg/10mg Tablet?

Pregacent NT 75mg/10mg Tablet can make you feel hungry, which might make you eat more, thereby increasing your chances of putting on weight.. However, preventing weight gain is easier than losing increased weight. Try to eat a healthy balanced diet without increasing your portion sizes (per-meal intake). DO not eat foods that contain a lot of calories, such as soft drinks, oily food, chips, cakes, biscuits, and sweets. If you feel hungry between meals, avoid eating junk food and eat fruits, vegetables, and low-calorie foods. Regular exercise will prevent weight gain. If you maintain good eating habits and exercise regularly, you might not gain any weight.

Can the use of Pregacent NT 75mg/10mg Tablet cause sleepiness or drowsiness?

Yes, Pregacent NT 75mg/10mg Tablet may make you feel drowsy, or you may suddenly fall asleep during your daily activities. Sometimes, you might not even feel drowsy or have any other warning signs before you suddenly fall asleep. Avoid driving a car, operating machinery, working at heights, or participating in potentially dangerous activities at the beginning of your treatment until you know how the medicine affects you. Inform your doctor if you experience such episodes while taking this medicine.

What if I forget to take Pregacent NT 75mg/10mg Tablet?

If you forget to take the scheduled dose of Pregacent NT 75mg/10mg Tablet, and it is almost time for your next dose, skip the dose you missed and take your next dose at the scheduled time. Otherwise, take it as soon as you remember, and then go back to taking your medicine as you would normally. Do not take a double dose to make up for the dose you missed because this may increase the risk of unwanted side effects due to overdosage. If you are not sure what to do, consult your doctor about how to manage a situation like this.

Will Pregacent NT 75mg/10mg Tablet be more effective if a higher than the recommended dosage is taken?

No, taking a higher-than-recommended dose may not be more effective; rather, it may increase the chances of having some serious side effects and toxicity. If you experience increased severity of your symptoms that are not relieved by the recommended doses, please consult your doctor for re-evaluation.

Is there anything I need to avoid while taking Pregacent NT 75mg/10mg Tablet?

Pregacent NT 75mg/10mg Tablet may impair your thinking or reactions. Be careful while driving or doing an activity that requires you to be alert. Do not drink alcohol while you are taking Pregacent NT 75mg/10mg Tablet. It can increase the effects of alcohol, which could be dangerous. Grapefruit and grapefruit juice may also interact with this medicine and cause unwanted side effects. Avoid exposure to sunlight or tanning beds. Use of Pregacent NT 75mg/10mg Tablet can make you more prone to sunburns. Wear protective clothing and use sunscreen when you are outdoors during daytime.

How often should I see the doctor?

You may need to see your doctor regularly if you have started to take Pregacent NT 75mg/10mg Tablet. However, you must consult your doctor if the advised dosage of Pregacent NT 75mg/10mg Tablet does not improve your symptoms or if you continue experiencing some unwanted side effects that affect your routine activities. Pregacent NT 75mg/10mg Tablet can make you more prone to sunburns. Wear protective clothing and use sunscreen when you are outdoors during daytime.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Pregabalin [Prescribing Information]. Vega Baja, Puerto Rico: Pfizer Pharmaceuticals LLC; 2009. [Accessed 22 Apr. 2019] (online) Available from:
Pregabalin [Prescribing Information]. New York, NY: Pfizer; 2011. [Accessed 22 Apr. 2019] (online) Available from:
Pregabalin and Nortriptyline [Product Information]. Ahmedabad, Gujarat: La Renon Healthcare Limited. [Accessed 28th Sept. 2023] (online) Available from:
Pregabalin+Nortriptyline [Prescribing Information]. Mumbai, Maharashtra: Alkem Laboratories Limited. [Accessed 28th Sept. 2023] (online) Available from:
Nortriptyline [Prescribing Information]. Middlesex, London: Brown & Burk UK Ltd. 2025 [Accessed 14 Apr. 2025] (online) Available from: