Pregamer Plus Tablet
Prescription Required
Product introduction
Pregamer Plus Tablet is used to treat neuropathic pain. It decreases the pain by controlling calcium channel activity and by decreasing the production of a substance that protects nerve fibers and rejuvenates damaged nerve cells.
Pregamer Plus Tablet can be taken on empty stomach. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important not to stop taking this medicine suddenly without talking to the doctor.
Common side effects of this medicine include dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. It may also cause nasopharyngitis, increased appetite, confusion, difficulty in sleeping, decreased libido, tremor, vision blurred, and vertigo. Inform your doctor if you develop any unusual changes in the mood or behavior, new or worsening depression, or suicidal thoughts. It is better to avoid alcohol while taking this medicine as it can enhance the dizziness effect of the drug.
Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Uses of Pregamer Plus Tablet
Side effects of Pregamer Plus Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Pregamer Plus
- Dizziness
- Sleepiness
- Tiredness
- Uncoordinated body movements
- Nasopharyngitis (inflammation of the throat and nasal passages)
- Increased appetite
- Confusion
- Insomnia (difficulty in sleeping)
- Decreased libido
- Tremors
- Vertigo
- Blurred vision
How to use Pregamer Plus Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pregamer Plus Tablet is to be taken empty stomach.
How Pregamer Plus Tablet works
Pregamer Plus Tablet is a combination of five medicines: Alpha Lipoic Acid, Folic Acid, Methylcobalamin, Pregabalin and Vitamin B6 (Pyridoxine). Alpha Lipoic Acid is a naturally occurring fatty acid which has a protective effect on the brain and nerve tissues. Folic Acid provides essential nutrients to the nerves. Methylcobalamin and Vitamin B6 (Pyridoxine) are forms of vitamin B which help in the production of myelin, a substance that protects nerve fibers and rejuvenates damaged nerve cells. Pregabalin is an alpha 2 delta ligand which decreases pain by modulating calcium channel activity of the nerve cells. Together, they relieve neuropathic pain (pain from damaged nerves).
Safety advice
Alcohol
CAUTION
Caution is advised when consuming alcohol with Pregamer Plus Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Pregamer Plus Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Pregamer Plus Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Pregamer Plus Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Pregamer Plus Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Pregamer Plus Tablet may not be needed in these patients. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Pregamer Plus Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Pregamer Plus Tablet may not be needed in these patients. Please consult your doctor.
What if you forget to take Pregamer Plus Tablet?
If you miss a dose of Pregamer Plus Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
- Pregamer Plus Tablet helps treat nerve pain caused by diabetes, shingles or an injury.
- Its side effects are usually mild and go away by themselves.
- It may cause sleepiness. Don't drive or do anything requiring concentration until you know how it affects you.
- Avoid consuming alcohol when taking this medicine, as it may cause excessive sleepiness or drowsiness.
- Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
- Do not stop taking the medication suddenly without talking to your doctor.
Fact Box
Habit Forming
No
Therapeutic Class
NEURO CNS
Patient concerns
FAQs
What is Pregamer Plus Tablet?
Pregamer Plus Tablet is a combination of five medicines: Pregabalin, Methylcobalamin, Folic acid, Alpha lipoic acid, and Vitamin B6. This medicine is useful in the treatment of nerve pain (neuropathic pain). This medicine calms the damaged or overactive nerves by acting on the brain, thereby decreasing the pain sensation. It also helps in the regeneration of damaged nerves in the body.
Can I stop taking Pregamer Plus Tablet when my pain is relieved?
No, you should not stop taking Pregamer Plus Tablet even if your pain is relieved. Continue to take it as advised by your doctor. If you suddenly stop taking Pregamer Plus Tablet, you may experience withdrawal symptoms such as anxiety, sleeping difficulties, nausea, pain and sweating. You may need to gradually taper the use of Pregamer Plus Tablet before you stop the medication completely.
How to manage weight gain associated with the use of Pregamer Plus Tablet?
Pregamer Plus Tablet can make you feel hungry which might make you eat more, thereby increasing your chances of putting on weight. However, preventing weight gain is easier than losing the increased weight. Try to eat a healthy balanced diet without increasing your portion sizes (per-meal intake). Do not eat food items that contain a lot of calories, such as soft drinks, oily food, chips, cakes, biscuits and sweets. If you feel hungry between meals, avoid eating junk food and eat fruits, vegetables and low-calorie foods. Regular exercise will help prevent weight gain. If you maintain good eating habits and exercise regularly, you might not gain any weight.
Can the use of Pregamer Plus Tablet cause sleepiness or drowsiness?
Yes, Pregamer Plus Tablet may make you feel drowsy or you may suddenly fall asleep during your daily activities. Sometimes, you might not even feel drowsy or have any other warning signs before you suddenly fall asleep. Avoid driving a car, operating machinery, working at heights or participating in potentially dangerous activities until you know how the medicine affects you. Inform your doctor if you experience such episodes while you are taking this medicine.
Are there any serious side effects associated with the use of Pregamer Plus Tablet?
Serious side effects because of Pregamer Plus Tablet are uncommon and rare. However, it may cause serious side effects like an allergic reaction, suicidal thoughts or swelling of limbs (hands, legs or feet). Stop taking Pregamer Plus Tablet and contact your health care provider if you have any signs of these serious side effects. Signs of allergic reaction include swelling of your face, mouth, lips, gums, tongue and neck, trouble in breathing, skin rash, hives (raised bumps) or blisters. Pay attention to sudden changes in mood, behaviors, thoughts, or feelings as these may be a symptom of suicidal thoughts.
How long will Pregamer Plus Tablet take to act?
An initial benefit with Pregamer Plus Tablet may be seen after 2 weeks of treatment. However, it may take around 2-3 months to see the full benefit. It may take longer in some patients.
What if I forget to take Pregamer Plus Tablet?
If you forget to take the scheduled dose of Pregamer Plus Tablet and it is almost time for your next dose, skip the dose you missed and take your next dose at the scheduled time. Otherwise, take it as soon as you remember, and then go back to taking your medicine as you would normally. Do not take a double dose to make up for the dose you missed because this may increase the risk of unwanted side effects. If you are not sure what to do, consult your doctor about how to manage a situation like this.
What if I take too much of this drug by mistake?
In a situation like this, contact your doctor immediately or seek emergency help at the nearest hospital. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention. Symptoms of an overdose may include drowsiness, weakness, unsteadiness while walking, having double visions, slurred speech or diarrhea, confusion, blurred vision, dizziness, body temperature changes (low and high), difficulty in breathing and increased heartbeat.
Will a higher than the recommended dose of Pregamer Plus Tablet be more effective?
No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having some serious side effects and toxicity. If you experience increased severity of your symptoms, that are not relieved by the recommended doses, please consult your doctor for re-evaluation.
Can I drink alcohol while taking Pregamer Plus Tablet?
No, do not drink alcohol while you are taking Pregamer Plus Tablet. Drinking alcohol can increase the severity of drowsiness or sleepiness caused by Pregamer Plus Tablet.
How often should I see the doctor?
You may need to see your doctor regularly if you have started to take Pregamer Plus Tablet. However, consult your doctor if the recommended dosage does not improve your symptoms or you continue experiencing some unwanted side effect that affect your routine activities.
What are the instructions for the storage and disposal of Pregamer Plus Tablet?
Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- MedlinePlus. Vitamin B12. [Accessed 22 Apr. 2019] (online) Available from:
- Pregabalin. Vega Baja, Puerto Rico: Pfizer Pharmaceuticals LLC; 2009. [Accessed 22 Apr. 2019] (online) Available from:
- Mayo Clinic. Vitamin B-6. [Accessed 22 Apr. 2019] (online) Available from:
- Pregabalin, Methylcobalamin, Alpha Lipoic Acid, Pyridoxine Hydrochloride and Folic Acid [Patient Information Sheet]. Solan, HP: Innova Captab Ltd.; 2021. [Accessed 14 Aug. 2024] (online) Available from:
Country of origin: India
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