Pregawin 50 Capsule is a combination medicine used in the treatment of neuropathic pain. It calms the damaged or overactive nerves by acting on the brain, thereby decreasing the pain sensation. It also helps in the regeneration of damaged nerves in the body.
Pregawin 50 Capsule is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor as this is a habit-forming medicine. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to the doctor.
Some common side effects of this medicine include dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. The side effects are mild in nature and get improve with time. This medicine may cause weight gain and to control it, you should exercise regularly and take a balanced diet. It is important to inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts.
Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Pregawin
Sleepiness
Dizziness
Headache
Nasopharyngitis (inflammation of the throat and nasal passages)
Increased appetite
Confusion
Disorientation
Abnormality of voluntary movements
Balance disorder (loss of balance)
Lethargy
Blurred vision
Vertigo
Vomiting
Constipation
Muscle cramp
Edema (swelling)
Erectile dysfunction
Weight gain
How to use Pregawin Capsule
Take this medicine in the dose and duration as advised by your doctor. Pregawin 50 Capsule may be taken with or without food, but it is better to take it at a fixed time.
How Pregawin Capsule works
Pregawin 50 Capsule is a combination of three medicines: Pregabalin, Methylcobalamin and Alpha Lipoic Acid. Pregabalin is an alpha 2 delta ligand which decreases pain by modulating calcium channel activity of the nerve cells. Methylcobalamin is a form of vitamin B which helps in the production of myelin, a substance that protects nerve fibers and rejuvenates damaged nerve cells. Alpha Lipoic Acid is a naturally occurring fatty acid which has a protective effect on brain and nerve tissue. Together, they relieve neuropathic pain (pain from damaged nerves).
Safety advice
Alcohol
CAUTION
Caution is advised when consuming alcohol with Pregawin 50 Capsule. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Pregawin 50 Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Pregawin 50 Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Pregawin 50 Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Pregawin 50 Capsule is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Pregawin 50 Capsule may not be needed in these patients. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Pregawin 50 Capsule is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Pregawin 50 Capsule may not be needed in these patients. Please consult your doctor.
What if you forget to take Pregawin Capsule?
If you miss a dose of Pregawin 50 Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Sir Plz suggest me effective pain killer with minimum side effects for back pain and arthritis, which can be taken on regular basis as and when required.
Dr. Vikas Sharma
Neurology
dpeneds on the type of pain - muscular or neuropathic; show tro nearby neuro
Burning sensation in sole ,penile region regularly No spot at penile area but constant burning sensation at sole and penile area No relief from amoxicillin,ceprofloxin doxycyclene Period :last 14 days
Dr. Pranay Gandhi
Sexology
that may be a neuropathic pain. do u have high bp or diabetes. take tablet pregama m 1 od for 15 days
I suffered from brain stroke. How long can I use gabapentin 300 mg tablets ?
Dr. Anshul Varshney
Physician
Hello, Welcome to 1mg. I am Anshul Varshney for your help. This medicine is used to calm down the neuropathic pain. You may take it till you feel better. Later your doctor may reduce the dose and stop it.
I m suffering due to pain in left testis, so I visited pgimer Chandigarh in urology deptt. There I had gone for dopler ultrasound testis and its reports are normal Now whenever I lay down at bed I felt a smaal lump in testis,when I touchdown it, the pain radiates in whole left testis Now I m feeling pain sometimes in both tastis Is it a sign of early vericoseal Or something else Pls. Suggest
Dr. Pranay Gandhi
Sexology
it is a neuropathic pain and it won't show any abnormality in USG. i am worried about the lump u r talking about. its better if u consult a surgeon, PGIMER UROLOGY is the best place to go for examination. if they say its normal, its normal. for pain take pregaba m 1 od
Pregawin 50 Capsule is a combination of three medicines: Pregabalin, Methylcobalamin and Alpha lipoic acid. This medicine is useful in the treatment of nerve pain (neuropathic pain). This medicine calms the damaged or overactive nerves by acting on the brain, thereby decreasing the pain sensation. It also helps in the regeneration of damaged nerves in the body.
Q. Can I stop taking Pregawin 50 Capsule when my pain is relieved?
No, you should not stop taking Pregawin 50 Capsule even if your pain is relieved. Continue to take it as advised by your doctor. If you suddenly stop taking Pregawin 50 Capsule, you may experience withdrawal symptoms such as anxiety, sleeping difficulties, nausea, pain, and sweating. You may need to gradually taper the use of Pregawin 50 Capsule before you stop the medication completely.
Q. How to manage weight gain associated with the use of Pregawin 50 Capsule?
Pregawin 50 Capsule can make you feel hungry which might make you eat more, thereby increasing your chances of putting on weight. However, preventing weight gain is easier than losing increased weight. Try to eat a healthy balanced diet without increasing your portion sizes (per-meal intake). Do not eat foods that contain a lot of calories, such as soft drinks, oily food, chips, cakes, biscuits and sweets. If you feel hungry between meals, avoid eating junk foods and eat fruits, vegetables and low-calorie foods. Regular exercise will also help you prevent weight gain. If you keep good eating habits and exercise regularly, you might not gain any weight.
Q. Can the use of Pregawin 50 Capsule cause sleepiness or drowsiness?
Yes, Pregawin 50 Capsule may make you feel drowsy or you may suddenly fall asleep during your daily activities. Sometimes, you might not even feel drowsy or have any other warning signs before you suddenly fall asleep. Avoid driving a car, operating machinery, working at heights or participating in potentially dangerous activities until you know how the medicine affects you. Inform your doctor if you experience such episodes while you are taking this medicine.
Q. Are there any serious side effects associated with the use of Pregawin 50 Capsule?
Serious side effects with Pregawin 50 Capsule are uncommon and rare. However, it may cause serious side effects like an allergic reaction, suicidal thoughts or swelling of limbs (hands, legs or feet). Stop taking Pregawin 50 Capsule and contact your doctor if you have any signs of these serious side effects. Signs of allergic reaction include swelling of your face, mouth, lips, gums, tongue and neck if you are having trouble in breathing, skin rash, hives (raised bumps) or blisters. Pay attention to any changes, especially sudden changes in mood, behavior, thoughts or feelings which may be a symptom of suicidal tendency.
Q. What if I forget to take Pregawin 50 Capsule?
If you forget to take the scheduled dose of Pregawin 50 Capsule and it is almost time for your next dose, skip the dose you missed and take your next dose at the scheduled time. Otherwise, take it as soon as you remember, and then go back to taking your medicine as you would normally. Do not take a double dose to make up for the dose you missed because this may increase the risk of unwanted side effect. If you are not sure what to do, ask your doctor about taking Pregawin 50 Capsule.
Q. What if I take too much of Pregawin 50 Capsule by mistake?
In a situation like this, contact your doctor immediately or seek emergency help at the nearest hospital. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention. Symptoms of an overdose may include drowsiness, weakness, unsteadiness while walking, having double visions, slurred speech or diarrhea, confusion, blurred vision, dizziness, body temperature changes (low and high), difficulty in breathing and increased heartbeat.
Q. Will a higher than the recommended dose of Pregawin 50 Capsule be more effective?
No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having some serious side effects and toxicity. If you experience increased severity of your symptoms, that are not relieved by the recommended doses, please consult your doctor for re-evaluation.
Q. How often should I see the doctor ?
You may need to see your doctor regularly if you have started to take Pregawin 50 Capsule. However, if the recommended dosage does not relieve your symptoms or you experience some unwanted side effect that affects your routine activities, consult your doctor.
Q. What are the instructions for the storage and disposal of Pregawin 50 Capsule?
Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
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References
Pregabalin. Vega Baja, Puerto Rico: Pfizer Pharmaceuticals LLC; 2009. [Accessed 22 Apr. 2019] (online) Available from:
MedlinePlus. Vitamin B12. [Accessed 22 Apr. 2019] (online) Available from:
Pregabalin, Methylcobalamin, Alpha Lipoic Acid, Pyridoxine Hydrochloride and Folic Acid [Patient Information Sheet]. Solan, Himachal Pradesh: Torrent Pharmaceuticals Ltd.; 2021. [Accessed 21 Aug. 2024] (online) Available from: