Premarin Tablet is a female sex hormone (estrogen). It is a part of female hormone replacement therapy which helps in treating estrogen deficiency symptoms like hot flushes (red and warm face) and vaginal dryness.
In some cases, Premarin Tablet is also used to treat breast cancer and prostate cancer along with other anticancer medicines. It is to be taken at a fixed time(s) daily. The dose and duration will be decided by your doctor so that you get the right amount to control your symptoms. If you have missed a dose, take it as soon as you remember it. Do not skip any dose and finish the full course of treatment. The treatment should not be stopped abruptly without consulting your doctor as this may affect the potency of this medicine.
The most common side effects of this HRT are headaches, breast pain, irregular vaginal bleeding or spotting, abdominal cramps or bloating, nausea, vomiting, and hair loss. Some of the warning signs and symptoms that need immediate medical attention are breast lumps, unusual vaginal bleeding, dizziness and faintness, severe headaches, chest pain, shortness of breath, pains in your legs, etc.
Before taking this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same disease or other diseases. Before you initiate with this HRT, you must consult the doctor if you have a history of unexplained vaginal bleeding or if you have ever had a blood clot in your legs or your lungs. If you are pregnant or breastfeeding, you should tell your doctor before taking this medicine. Your doctor may suggest you some diagnostic or laboratory tests to know the effects and side effects of this medicine on your body.
Osteoporosis is a common condition that weakens bones, making them fragile and more likely to break. It often occurs in women after menopause (end of a woman's menstrual cycles) and is known as post-menopausal osteoporosis. Premarin Tablet helps to keep your bones strong and healthy and reduces the risk of osteoporosis. It also helps maintain bone density and reduces your risk of bone fracture. You should use this medicine as it is prescribed, and for as long as it is prescribed by your doctor.
In Hormone replacement therapy
Hormone placement therapy (HRT) is a treatment to relieve symptoms of menopause such as hot flushes, night sweats, mood swings, vaginal dryness, and reduced sex drive. Since menopause can last for several years, this treatment can make a big improvement to your daily life and mood. Estrogen is one of two important hormones (the other is progesterone) used in this treatment. You should use this medicine as it is prescribed, and for as long as it is prescribed by your doctor.
Side effects of Premarin Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Premarin
Nausea
Breast pain
Hair loss
Irregular vaginal bleeding
Edema (swelling)
Vaginal spotting
Vaginal itching
Depression
Leg cramps
Abdominal cramp
Vaginal burning sensation
How to use Premarin Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Premarin Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Premarin Tablet works
Premarin Tablet is a mixture of estrogens (female sex hormone). In women who are undergoing or have attained menopause, it prevents symptoms such as hot flushes, night sweats and mood swings. It also prevents the bones from becoming porous and fragile (osteoporosis).
Safety advice
Alcohol
CAUTION
Caution is advised when consuming alcohol with Premarin Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Premarin Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Premarin Tablet during breastfeeding is not available. Please consult your doctor.
Driving
CONSULT YOUR DOCTOR
It is not known whether Premarin Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
UNSAFE
Premarin Tablet is probably unsafe to use in patients with kidney disease and should be avoided. Please consult your doctor.
Liver
UNSAFE
Premarin Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
What if you forget to take Premarin Tablet?
If you miss a dose of Premarin Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
You have been prescribed Premarin Tablet as a part of hormone replacement therapy to relieve symptoms of menopause.
It may also be used for preventing osteoporosis in postmenopausal women who are at high risk of fractures.
Take it at the same time everyday to help you remember to take it.
Inform your doctor if you experience any unusual vaginal bleeding or spotting, abnormal vaginal discharge or vaginal discomfort while taking Premarin Tablet.
It may increase the risk of breast cancer. Have regular breast examinations.
Stop taking this medicine and inform your doctor immediately if you notice unexplained swelling and pain in your limbs, shortness of breath, chest pain, or changes in vision. These could be symptoms of a blood clot in a vein.
Fact Box
Chemical Class
Estradiol Congeners
Habit Forming
No
Therapeutic Class
GYNAECOLOGICAL
Action Class
Estrogens
Patient concerns
Dry vagina, Best Lube for easy penetration
Dr. Shyam Gupta
Obstetrics and Gynaecology
Hello PATIENT Premarin cream vaginally. It will improve this.
already removed uterus(hysterectomy)I using medicine PREMARIN.625 since2010.my prescription has been missed.i want purchase PREMARIN by online.so can u prescribe this medicine. thanks
Having urine burning problem past month. with the homeop medicine 70% relief i got. now i stopped medicine to have. five year back hystectomy done overies still remain. due to computer work eyes get dried and tired. shoulders also pain. past 1.7 year back pain started. some time hot flashes also come suddenly. all blood investigation and u/s are normal. as per dr. advise take sweet less. hair fall are more. no dandruff.
Dr. Megha Tuli
Obstetrics and Gynaecology
It is normal to have hot flashes and these post menopausal symptoms after hysterectomyYou can take hormone therapy if you want however symptoms will recurrent when you stop treatment
Hello Dr. My mother is 63 years old and her weight is appx. 68 kg. She is suffering from osteoporosis arthritis. I consult to many doctors all suggest me for joint replacement. I want to know, is joint replacement is successful treatment in such age group.
Dr. Aanchal Maheshwari
Ayurveda
yes, you can go for bone replacement therapy. there is no harm in it.
WHEN I HAVE INTERCOURSE WITH MY HUSBAND MY VAGINA IS VERY DRY .PLEASE SUGEST ANY CREAM & CONSELT .
Dr. Shyam Gupta
Obstetrics and Gynaecology
Hello PATIENT to 1mg. This dryness is due to hormonal changes. I need to evaluate with some test but for now you can apply Premarin cream alternate day and VWash sampoo while bathing.
*Hormone replacement therapy, Post menopausal osteoporosis, Dryness in vagina
How much was the improvement?
Poor
43%
Average
30%
Excellent
28%
What were the side-effects while using Premarin Tablet?
No Side Effec*
50%
Vomiting
17%
Headache
17%
Mood changes
17%
*No Side Effect
How do you take Premarin Tablet?
With food
67%
With or witho*
33%
*With or without food
Please rate Premarin Tablet on price
Expensive
78%
Average
22%
FAQs
What is Premarin Tablet and what is it used for?
Premarin Tablet contains a mixture of estrogens (a female sex hormone). It helps in treating estrogen deficiency symptoms like hot flushes (red and warm face), vaginal dryness in women. It is also used to prevent osteoporosis (thinning and weakening of bone) in postmenopausal women, who are at high risk of fractures and can not take other preventive medicines for osteoporosis.
When and how to take Premarin Tablet?
Take Premarin Tablet as per the advise by your doctor. However, you must try to take Premarin Tablet tablet at the same time of each day, to ensure the consistent levels of medicine in your body.
What if I miss to take Premarin Tablet?
If you miss a dose, you should take it as soon as possible. If the dose was missed by more than 12 hours, you should not take the missed dose and simply continue the usual dosing schedule.
What are the most common side effects which I may experience while taking Premarin Tablet?
The common side effects associated with Premarin Tablet are lower abdominal pain, periods pain, breast tenderness, endometrial hyperplasia (thickening of uterus lining) and vaginal discharge. Most of these symptoms are temporary. However, if they persist, check with your doctor as soon as possible.
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 501.
Mayo Clinic. Conjugated estrogens. [Accessed 03 Apr. 2019] (online) Available from:
Conjgated estrogen. Sandwich, Kent: Pfizer Limited; 2011 [revised Aug. 2016]. [Accessed 03 Apr. 2019] (online) Available from:
Gambacciani M, Levancini M. Hormone replacement therapy and the prevention of postmenopausal osteoporosis. Prz Menopauzalny. 2014 Sep;13(4):213-20. [Accessed 20 Feb. 2024] (online) Available from:
Conjugated oestrogens [Package leaflet: Information for the user]. County Kildare, Republic of Ireland: Pfizer Ireland Pharmaceuticals; 2023. [Accessed 20 Feb. 2024] (online) Available from:
Country of origin: India Expires on or after: July, 2026
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