Primiwal-E4 Tablet SR
Prescription Required
Product introduction
Primiwal-E4 Tablet SR is a female sex hormone (estrogen). This is a type of hormone replacement therapy (HRT) that is used to treat symptoms associated with menopause (hot flushes, vaginal dryness, and itching), estrogen deficiency, and thinning of bones (osteoporosis).
Primiwal-E4 Tablet SR is to be swallowed with water. It can be taken with or without food, but remember to take it at a fixed time each day for better efficacy. The dose and duration will be decided by your doctor so that you get the right amount to control your symptoms. If you have missed a dose, take it as soon as you remember it. Do not skip any dose and finish the full course of treatment. The treatment should not be stopped abruptly without consulting your doctor as this may affect the potency of this medicine.
The most common side effects of this HRT are headaches, breast pain, irregular vaginal bleeding or spotting, abdominal cramps or bloating, nausea, vomiting, and hair loss. Some of the warning signs and symptoms that need immediate medical attention are breast lumps, unusual vaginal bleeding, dizziness and faintness, severe headaches, chest pain, shortness of breath, pains in your legs, etc.
Before taking this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same disease or other diseases. Before you initiate with this HRT, you must consult the doctor if you have a history of unexplained vaginal bleeding or if you have ever had a blood clot in your legs or your lungs. If you are pregnant or breastfeeding, you should tell your doctor before taking this medicine. Your doctor may suggest you some diagnostic or laboratory tests to know the effects and side effects of this medicine on your body.
Primiwal-E4 Tablet SR is to be swallowed with water. It can be taken with or without food, but remember to take it at a fixed time each day for better efficacy. The dose and duration will be decided by your doctor so that you get the right amount to control your symptoms. If you have missed a dose, take it as soon as you remember it. Do not skip any dose and finish the full course of treatment. The treatment should not be stopped abruptly without consulting your doctor as this may affect the potency of this medicine.
The most common side effects of this HRT are headaches, breast pain, irregular vaginal bleeding or spotting, abdominal cramps or bloating, nausea, vomiting, and hair loss. Some of the warning signs and symptoms that need immediate medical attention are breast lumps, unusual vaginal bleeding, dizziness and faintness, severe headaches, chest pain, shortness of breath, pains in your legs, etc.
Before taking this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same disease or other diseases. Before you initiate with this HRT, you must consult the doctor if you have a history of unexplained vaginal bleeding or if you have ever had a blood clot in your legs or your lungs. If you are pregnant or breastfeeding, you should tell your doctor before taking this medicine. Your doctor may suggest you some diagnostic or laboratory tests to know the effects and side effects of this medicine on your body.
Uses of Primiwal-E4 Tablet SR
Benefits of Primiwal-E4 Tablet SR
In Hormone replacement therapy
Hormone placement therapy (HRT) is a treatment to relieve symptoms of menopause such as hot flushes, night sweats, mood swings, vaginal dryness, and reduced sex drive. Since menopause can last for several years, this treatment can make a big improvement to your daily life and mood. Estrogen is one of two important hormones (the other is progesterone) used in this treatment. You should use this medicine as it is prescribed, and for as long as it is prescribed by your doctor.
Side effects of Primiwal-E4 Tablet SR
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Primiwal-E4
- Headache
- Nausea
- Breast pain
- Abdominal cramp
- Bloating
- Vaginal spotting
- Vomiting
How to use Primiwal-E4 Tablet SR
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Primiwal-E4 Tablet SR may be taken with or without food, but it is better to take it at a fixed time.
How Primiwal-E4 Tablet SR works
Primiwal-E4 Tablet SR contains a medication called estrogen (female sex hormone). It works by replacing estrogen that is normally produced by the body. In women who are undergoing or have attained menopause, it prevents symptoms such as hot flushes, vaginal burning, dryness, and itching, caused due to lack of estrogen.
Safety advice
Alcohol
CAUTION
Caution is advised when consuming alcohol with Primiwal-E4 Tablet SR. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Primiwal-E4 Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
UNSAFE
Primiwal-E4 Tablet SR is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
SAFE
Primiwal-E4 Tablet SR does not usually affect your ability to drive.
Kidney
CAUTION
Primiwal-E4 Tablet SR should be used with caution in patients with kidney disease. Dose adjustment of Primiwal-E4 Tablet SR may be needed. Please consult your doctor.
Liver
CAUTION
Primiwal-E4 Tablet SR should be used with caution in patients with liver disease. Dose adjustment of Primiwal-E4 Tablet SR may be needed. Please consult your doctor.
Use of Primiwal-E4 Tablet SR is not recommended in patients who previously had liver disease and the liver function tests are still not normal and should not be given to women with severe hepatic disease.
Use of Primiwal-E4 Tablet SR is not recommended in patients who previously had liver disease and the liver function tests are still not normal and should not be given to women with severe hepatic disease.
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For informational purposes only. Consult a doctor before taking any medicines.
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Quick tips
- You have been prescribed Primiwal-E4 Tablet SR as a part of hormone replacement therapy to relieve symptoms of menopause.
- It may also be used for preventing osteoporosis in postmenopausal women who are at high risk of fractures.
- Take it at the same time everyday to help you remember to take it.
- Inform your doctor if you experience any unusual vaginal bleeding or spotting, abnormal vaginal discharge or vaginal discomfort while taking Primiwal-E4 Tablet SR.
- It may increase the risk of breast cancer. Have regular breast examinations.
- Stop taking this medicine and inform your doctor immediately if you notice unexplained swelling and pain in your limbs, shortness of breath, chest pain, or changes in vision. These could be symptoms of a blood clot in a vein.
Fact Box
Chemical Class
Estradiol Congeners
Habit Forming
No
Therapeutic Class
GYNAECOLOGICAL
Action Class
Estrogens
Interaction with drugs
Taking Primiwal-E4 with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Mycophenolate mofetil may reduce the efficacy of Estradiol.
Effective contraception must be used before, during, and for at least 6 weeks after stopping Mycophenolate mofetil. It
Concurrent use may result in contraceptive failure.
It is recommended to use barrier methods (like condoms), IUDs, or a depot for contraception. Your doctor may monitor your treat
If used together, Darunavir may affect blood levels of Estradiol.
It is recommended to use barrier methods (like condoms), IUDs, or a depot for contraception. Your doctor may moni
Concurrent use may increase the risk of formation of blood clots.
If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observatio
Concurrent use may increase the risk of blood clots.
If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.
Patient concerns
User feedback
Patients taking Primiwal-E4 Tablet SR
Once A Day
55%
Twice A Day
33%
Thrice A Day
11%
Four Times A *
1%
*Four Times A Day
What are you using Primiwal-E4 Tablet SR for?
Hormone repla*
60%
Others
20%
Contraception
15%
Post menopaus*
5%
*Hormone replacement therapy, Post menopausal osteoporosis
How much was the improvement?
Average
60%
Poor
23%
Excellent
17%
What were the side-effects while using Primiwal-E4 Tablet SR?
Headache
40%
No Side Effec*
20%
Sexual dysfun*
20%
Change in bod*
20%
*No Side Effect, Sexual dysfunction, Change in body weight
How do you take Primiwal-E4 Tablet SR?
With food
89%
Empty stomach
11%
Please rate Primiwal-E4 Tablet SR on price
Average
58%
Expensive
29%
Not Expensive
12%
FAQs
What is Primiwal-E4 Tablet SR and what is it used for?
Primiwal-E4 Tablet SR contains Estradiol, which is an estrogen hormone. It helps in treating estrogen deficiency symptoms like hot flushes (red and warm face) and vaginal dryness in women. It is also used to prevent osteoporosis (thinning and weakening of bones) in postmenopausal women, who are at high risk of fractures and have limited treatment choice.
What if I miss a dose of Primiwal-E4 Tablet SR?
If you miss a dose, you should take it as soon as possible. If the dose was missed by more than 12 hours, you should not take the missed dose and simply continue the usual dosing schedule.
What are the most common side effects which I may experience while taking Primiwal-E4 Tablet SR?
The common side effects associated with Primiwal-E4 Tablet SR are lower abdominal pain, periods pain, breast tenderness, endometrial hyperplasia (thickening of uterus lining) and vaginal discharge. Most of these symptoms are temporary. However, if these persist, check with your doctor as soon as possible.
What can I take for estrogen deficiency?
For estrogen deficiency, treatment is based on the underlying cause. Your doctor may choose from a variety of medications depending upon your age and clinical conditions. The medications will also depend upon whether you are estrogen deficient or have high progesterone levels.
Who should not take Primiwal-E4 Tablet SR?
Primiwal-E4 Tablet SR should not be taken by patients who have unusual vaginal bleeding, liver problems, or bleeding disorder. It should also be avoided to patients who are pregnant or are allergic to Primiwal-E4 Tablet SR. Patients who have had uterus or breast cancer, had a stroke or heart attack, or currently have or had blood clots should also avoid this medicine.
Does Primiwal-E4 Tablet SR cause weight gain?
Primiwal-E4 Tablet SR may cause either weight gain or weight loss. This is a common side effect of Primiwal-E4 Tablet SR. However, exercising regularly and eating a healthy nutritious diet can help you prevent weight gain. In case you notice weight gain and it bothers you, consult your doctor.
How should Primiwal-E4 Tablet SR be taken?
Primiwal-E4 Tablet SR tablets should be taken exactly as advised by your doctor. Swallow the tablets whole with water. You can take it at any time of the day but take it at the same time each day.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Levin ER, Hammes SR. Estrogens and Progestins. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1173-75.
- Masters SB. Hypothalmic & Pituitary Hormones. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 701-702.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 500-501.
- MedIndia. Estradiol. [Accessed 03 Apr. 2019] (online) Available from:
- Estradiol. Rockaway, New Jersey: Warner Chilcot; 2009. [Accessed 03 Apr. 2019] (online) Available from:
- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 01 Apr. 2019] (online) Available from:
- CiplaMed. Estradiol valerate [Prescribing Information]. [Last Revised: February 2021]. [Accessed 24 June 2023]. (online) Available from:
Marketer details
Name: Bharat Serums & Vaccines Ltd
Address: 17th Floor, Hoechst House, Nariman Point, Mumbai – 400 021, Maharashtra, India.
Country of origin: India
Expires on or after: April, 2026
A licensed vendor partner from your nearest location will deliver Primiwal-E4 Tablet SR. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Expires on or after: April, 2026
A licensed vendor partner from your nearest location will deliver Primiwal-E4 Tablet SR. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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