Primox 25mg Tablet
Prescription Required
Product introduction
Primox 25mg Tablet is a tricyclic antidepressant that is used to treat depression and nighttime bedwetting (nocturnal enuresis). Additionally, it may also be prescribed for neuropathic pain.
Primox 25mg Tablet works by increasing the levels of chemical messengers in the brain that stabilizes and enhances the mood. It is better to take it before bedtime because it can make you feel drowsy. It can be taken with or without food, but you should take it at a fixed time each day for better efficacy. The dose and duration will be decided by your doctor so that you get the right amount to control your symptoms.
The most common side effects of this medicine include increased heart rate, blurred vision, dryness in the mouth, difficulty in urination, and constipation. Initially, this medicine may also cause a sudden drop in blood pressure when you change positions. It may even cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. To lower the chance of dizziness, rise slowly if you have been sitting or lying down. It may also lead to weight gain in some people. Most of the common side effects tend to be mild and temporary. Your doctor may be able to suggest ways of preventing or reducing side effects if they bother you or do not go away. Serious side effects associated with this medicine are rare.
Before taking this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same or any other diseases. Pregnant and breastfeeding women should take this medicine with proper consultation and caution. This medicine is not known to be addictive, but you can experience additional side effects (withdrawal symptoms) if you stop taking it suddenly. If you notice any sudden mood change or get suicidal or self-harm thoughts, you must consult the doctor without delay. Also, remember to take this medicine strictly as advised by the doctor as an overdose of this medication may lead to a serious health emergency. Consumption of alcohol should be avoided as alcohol interacts with this medicine to cause serious health issues.
Primox 25mg Tablet works by increasing the levels of chemical messengers in the brain that stabilizes and enhances the mood. It is better to take it before bedtime because it can make you feel drowsy. It can be taken with or without food, but you should take it at a fixed time each day for better efficacy. The dose and duration will be decided by your doctor so that you get the right amount to control your symptoms.
The most common side effects of this medicine include increased heart rate, blurred vision, dryness in the mouth, difficulty in urination, and constipation. Initially, this medicine may also cause a sudden drop in blood pressure when you change positions. It may even cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. To lower the chance of dizziness, rise slowly if you have been sitting or lying down. It may also lead to weight gain in some people. Most of the common side effects tend to be mild and temporary. Your doctor may be able to suggest ways of preventing or reducing side effects if they bother you or do not go away. Serious side effects associated with this medicine are rare.
Before taking this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same or any other diseases. Pregnant and breastfeeding women should take this medicine with proper consultation and caution. This medicine is not known to be addictive, but you can experience additional side effects (withdrawal symptoms) if you stop taking it suddenly. If you notice any sudden mood change or get suicidal or self-harm thoughts, you must consult the doctor without delay. Also, remember to take this medicine strictly as advised by the doctor as an overdose of this medication may lead to a serious health emergency. Consumption of alcohol should be avoided as alcohol interacts with this medicine to cause serious health issues.
Uses of Primox Tablet
Side effects of Primox Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Primox
- Increased heart rate
- Weight gain
- Difficulty in urination
- Orthostatic hypotension (sudden lowering of blood pressure on standing)
- Dryness in mouth
- Constipation
- Blurred vision
How to use Primox Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Primox 25mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Primox Tablet works
Primox 25mg Tablet is a tricyclic antidepressant. It increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.
Safety advice
Alcohol
UNSAFE
Primox 25mg Tablet may cause excessive drowsiness with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
Primox 25mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Primox 25mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Primox 25mg Tablet may cause side effects which could affect your ability to drive.
As Primox 25mg Tablet may affect your alertness which may affect your ability to drive.
As Primox 25mg Tablet may affect your alertness which may affect your ability to drive.
Kidney
CAUTION
Primox 25mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Primox 25mg Tablet may be needed. Please consult your doctor.
Liver
CAUTION
Primox 25mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Primox 25mg Tablet may be needed. Please consult your doctor.
Inform your doctor if you develop any signs and symptoms of jaundice while taking this medicine. Use of Primox 25mg Tablet is not recommended in patients with severe liver disease.
Inform your doctor if you develop any signs and symptoms of jaundice while taking this medicine. Use of Primox 25mg Tablet is not recommended in patients with severe liver disease.
What if you forget to take Primox Tablet?
If you miss a dose of Primox 25mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Primox 25mg Tablet
₹4.5/Tablet
Sensival 25 Tablet
Wallace Pharmaceuticals Pvt Ltd
₹5.7/tablet
27% costlier
Nortimer 25mg Tablet
Intas Pharmaceuticals Ltd
₹6.1/tablet
36% costlier
Rostryp 25mg Tablet
Rosswelt Biosciences
₹4.07/tablet
10% cheaper
Nortrip 25mg Tablet
A N Pharmacia
₹2.71/tablet
40% cheaper
Nortin 25mg Tablet
Manas Pharma MFG
₹3.69/tablet
18% cheaper
Quick tips
- Primox 25mg Tablet is used for the treatment of depression and bedwetting in children.
- The main dose should be taken at night as this drug may cause drowsiness or sleepiness.
- You may be asked for regular blood tests to monitor the blood cell count or level of sodium and sugar in the blood.
- Inform your doctor if you notice behavioral changes, mood changes and suicidal thoughts while taking this medicine.
- Do not drive or do anything that requires concentration until you know how the medicine affects you.
- Do not stop taking the medication suddenly without talking to your doctor.
- The main dose should be taken at night as this medicine may produce drowsiness or sleepiness.
- It can take 2 to 3 weeks for Primox 25mg Tablet to start working.
- You should continue the treatment for at least 6 months after you feel better to stop depression from coming back.
- If your doctor asks you to stop Primox 25mg Tablet, you should reduce the dose slowly over 4 weeks. You should not discontinue it abruptly.
- Avoid driving or operating machinery as it may decrease alertness.
- Avoid consuming alcohol when taking the Primox 25mg Tablet, as it may cause excessive drowsiness and calmness.
- The addiction/dependence potential of Primox 25mg Tablet is very less.
- It may be extremely dangerous in overdose.
Fact Box
Chemical Class
Dibenzocycloheptene Derivative
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Tricyclic Antidepressants (TCAs)
Interaction with drugs
Taking Primox with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concomitant use may cause a fatal increase in blood serotonin levels. Patients may experience agitation, increased body temperature, fast heartbeat, muscle rigidity, and loss of co
Concomitant use may cause an increase in blood serotonin levels. Patients may experience agitation, increased body temperature, fast heartbeat, muscle rigidity, and loss of coordin
Concomitant use may affect heart rhythm and can be fatal.
Do not consume Domperidone with Nortriptyline.
Concurrent use may cause serotonin syndrome.
Careful consideration is advised if you have epilepsy. Watch out for symptoms of serotonin syndrome, such as sedation, respiratory imp
Concurrent use may cause serious disturbance in heart rhythm.
If concurrent use is essential, watch out for symptoms such as sleepiness, dry mouth, impaired voluntary movements, w
Patient concerns
User feedback
Patients taking Primox 25mg Tablet
Once A Day
81%
Twice A Day
12%
Thrice A Day
5%
Alternate Day
3%
What are you using Primox Tablet for?
Depression
61%
Others
33%
Neuropathic p*
6%
*Neuropathic pain
How much was the improvement?
Average
63%
Excellent
37%
What were the side-effects while using Primox 25mg Tablet?
No Side Effec*
50%
Dryness in mo*
21%
Increased hea*
14%
Orthostatic h*
7%
Weight gain
7%
*No Side Effect, Dryness in mouth, Increased heart rate, Orthostatic hypotension (sudden lowering of blood pressure on standing)
How do you take Primox Tablet?
With food
80%
With or witho*
20%
*With or without food
Please rate Primox 25mg Tablet on price
Not Expensive
47%
Average
33%
Expensive
20%
FAQs
What is Primox 25mg Tablet used for?
Primox 25mg Tablet is used to treat depression and nocturnal (night time) bedwetting in children. It restores the chemical imbalance in the brain and enhances mood and behavior. In some cases, it may also be prescribed to relieve neuropathic (nerve) pain.
Can I take Primox 25mg Tablet for nerve pain? How do I know if I have nerve pain?
Yes, Primox 25mg Tablet can be taken for nerve pain. Your doctor may prescribe this medicine in combination with gabapentin. Nerve pain (or neuropathic pain) is commonly described as a shooting, burning or stabbing type of pain that may be associated with tingling, numbness or a pin and needles like feeling. The pain may be spontaneous which means it may be triggered without the presence of any stimulating factor. Additionally, you may experience an increase in the sensitivity to touch. Consult your doctor if you experience such pain.
What are the side effects of Primox 25mg Tablet?
The side effects of Primox 25mg Tablet are increased heart rate, weight gain, difficulty in urination, orthostatic hypotension (sudden decrease in blood pressure on standing), dryness in mouth and constipation. Please consult your doctor if these side effects do not go away or worry you.
Is Primox 25mg Tablet same as amitriptyline?
Primox 25mg Tablet and amitriptyline belong to the same category of medicines with similar action, but their effect may vary upon individual response.
Is Primox 25mg Tablet safe?
Primox 25mg Tablet is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.
Can I just stop taking Primox 25mg Tablet?
No, you must not stop taking Primox 25mg Tablet suddenly even if you are feeling better as it may worsen your condition. It may also cause withdrawal symptoms such as dizziness, nausea, vomiting, headache, weakness, sleep problems, fever and irritability. Continue taking Primox 25mg Tablet for the duration prescribed by your doctor to get maximum benefit. If any of the side effects are bothering you, consult your doctor. In case you have completed your course of treatment, your doctor will reduce your dose gradually before taking you off this medicine completely.
Is there anything I need to be careful about while on therapy with Primox 25mg Tablet?
Primox 25mg Tablet may cause drowsiness and dizziness, especially in the beginning of the treatment. Do not drive or work with tools or machinery if your alertness is affected. It is not advisable to drink alcohol during treatment with this medicine as it might worsen the drowsiness. Tell your doctor if you have any problems with your liver or kidneys. Let your doctor know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Inform your doctor if you are pregnant, planning to conceive or breastfeeding to prevent any harmful effects on the baby.
Can Primox 25mg Tablet cause urinary problems?
Yes, Primox 25mg Tablet can cause urinary problems. It is more commonly seen in elderly people who are above 65 years of age. The person may face difficulty in passing urine which can further lead to a urinary tract infection. You should consult your doctor immediately if you develop these symptoms.
What if I overdose?
An overdose of Primox 25mg Tablet can be significantly dangerous. In case of an overdose, you may experience symptoms such as blurred vision, fast or irregular heartbeats, dry mouth and tongue, fits and fever. You may also experience agitation (anxiety), confusion, hallucinations, uncontrolled movements, low blood pressure, difficulty breathing, discoloration of the skin (turning blue), drowsiness, loss of consciousness, or you may even go into a state of coma. Immediately consult your doctor and seek medical help if you have taken more than the recommended amount of Primox 25mg Tablet.
What if I miss a dose of Primox 25mg Tablet?
If you have missed a dose of Primox 25mg Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.
What all should I inform my doctor before taking Primox 25mg Tablet?
Before taking Primox 25mg Tablet, you should tell your doctor if you are allergic to Primox 25mg Tablet or any of its ingredients to avoid any allergic reactions. Inform your doctor if you have any problems with your heart, liver, thyroid, prostate or kidneys. Tell your doctor if you have or ever had epilepsy (seizures or fits), diabetes, or glaucoma. Let your doctor know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Also, inform your doctor if you are pregnant, planning to conceive or breastfeeding to prevent any harmful effects on the baby.
Is Primox 25mg Tablet effective?
Yes, Primox 25mg Tablet is effective if taken in the dose and duration prescribed by the doctor. Do not consume more than the recommended dose and avoid skipping doses. Inform your doctor if you experience any side effects while taking Primox 25mg Tablet to know about ways to manage or prevent them. It may take a few weeks for you to see improvement in your symptoms. However, the treatment may be continued for a few months for effective management of your condition.
Related ayurvedic ingredients
Want to share the information?
Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Stahl SM, editor. Nortriptyline. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 477-83.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1006-1007.
- Drugs.com. Nortriptyline Pregnancy and Breastfeeding Warnings. [Accessed 06 Mar. 2020] (online) Available from:
- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 25 Mar. 2019] (online) Available from:
Marketer details
Name: Sun Pharmaceutical Industries Ltd
Address: Plot no 107/108,Namli block , Ranipool, East Sikkim 737135
Country of origin: India
Expires on or after: August, 2026
A licensed vendor partner from your nearest location will deliver Primox 25mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Expires on or after: August, 2026
A licensed vendor partner from your nearest location will deliver Primox 25mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Lab tests offered by us
Related/Popular tests
42 people bought this recently₹38.25₹46Get 17% OFF
₹34.65+ free shipping with
Inclusive of all taxes
This offer price is valid on orders above ₹1800. Apply coupon HEALTHALL on the cart. Max. coupon discount is ₹380. T&C apply.
1 Strip
10.0 tablets in 1 strip
Cash on delivery available
Get it delivered by 10pm, Tomorrow
Delivering to:
122019, Gurgaon
Additional offers
Airtel Payments Bank: Pay with Airtel Payments Bank and get 10% cashback up to Rs. 200 cashback on a minimum transaction of ₹1000. Valid only for first-time users for Airtel Payments Bank Savings Bank accounts.
Show more 