Profen 400mg Tablet is a pain-relieving medicine. It is used to treat many conditions such as headache, fever, period pain, toothache, colds, and mild arthritis. It is also a common ingredient in many cold and flu remedies.

Profen 400mg Tablet should be taken with food to avoid stomach upset and reduce side effects. In general, you should try to use the smallest amount necessary to control your symptoms, for the shortest possible time. You should take this medicine regularly while you need it. Try not to miss doses as it will become less effective if you do.

The medicine is well tolerated with little or no side effects. However, it may cause vomiting, stomach pain, nausea, and indigestion in some people. If any of these side effects do not resolve with time or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.

This medicine is widely prescribed and considered safe but is not suitable for everybody. Before you take it, you should tell your doctor if you have kidney problems, asthma, blood disorders, or drink a lot of alcohol. Also, tell your doctor what other medicines you are taking to make sure you are safe. It is best to avoid drinking alcohol while using this medicine.

Uses of Profen Tablet

Benefits of Profen Tablet

In Pain relief

Profen 400mg Tablet is a common painkiller used to treat aches and pains. It blocks chemical messengers in the brain that tell us we have pain. It is effective in relieving pain caused by headache, migraine, nerve pain, toothache, sore throat, period (menstrual) pains, arthritis, and muscle aches. This medicine is very widely used and very rarely causes side effects if taken at the right dosage.

Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time.

In Treatment of Fever

Profen 400mg Tablet is also used to reduce a high temperature (fever). It works by blocking the release of certain chemical messengers that cause fever. It may be prescribed alone or in combination with another medicine. You should take it regularly as advised by your doctor.

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Side effects of Profen Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Profen

Vomiting
Nausea
Dizziness
Abdominal pain
Constipation
Flatulence
Diarrhea
Dyspepsia
Headache
Fatigue
Rash

How to use Profen Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Profen 400mg Tablet is to be taken with food.

How Profen Tablet works

Profen 400mg Tablet is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that cause fever, pain and inflammation (redness and swelling).

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Profen 400mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Profen 400mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Profen 400mg Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.

Driving

SAFE

Profen 400mg Tablet does not usually affect your ability to drive.

Kidney

CAUTION

Profen 400mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Profen 400mg Tablet may be needed. Please consult your doctor.
Use of Profen 400mg Tablet is not recommended in patients with severe kidney disease. Long term use of this medicine can affect the kidney function.

Liver

CAUTION

Profen 400mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Profen 400mg Tablet may be needed. Please consult your doctor.
Use of Profen 400mg Tablet is not recommended in patients with severe liver disease.

What if you forget to take Profen Tablet?

If you miss a dose of Profen 400mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Profen 400mg Tablet

₹0.97/Tablet

Brufen 400 Tablet

Abbott

₹1.27/tablet

31% costlier

Brufen 400 Tablet

Abbott

₹1.27/tablet

31% costlier

Ibugesic 400 Tablet

Cipla Ltd

₹0.7/tablet

28% cheaper

Maxofen Tablet

Abbott

₹0.58/tablet

40% cheaper

Novigan 400mg Tablet

Dr Reddy's Laboratories Ltd

₹0.98/tablet

1% costlier

View all substitutes

Quick tips

You have been prescribed Profen 400mg Tablet to relieve pain and inflammation.
Take it with food or milk to prevent upset stomach.
Take it as per the dose and duration prescribed by your doctor. Long term use may lead to serious complications such as stomach bleeding and kidney problems.
Do not take indigestion remedies (antacids) within two hours of taking Profen 400mg Tablet.
Avoid consuming alcohol while taking Profen 400mg Tablet as it can increase your risk of stomach problems.
Inform your doctor if you have a history of heart disease or stroke.
Your doctor may regularly monitor your kidney function, liver function and levels of blood components if you are taking this medicine for long-term treatment.

Fact Box

Chemical Class

Propionic acid Derivatives

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Action Class

NSAID's- Non-Selective COX 1&2 Inhibitors (propionic acid)

Patient concerns

fever and 2 months pregnant can take combiflan

Dr. Sonu Balhara Ahlawat

Obstetrics and Gynaecology

No take Crocin for pain relief

Diagnosed with viral fever along with rashes on the body. Pain in eyes since three days. Pain when open and when blinking.

Dr. Richa Jain

Ophthalmology

Orbital pain is common with viral fever. Go to physician for fever. It will be relieved with relief in fever

FAQs

Q. Is it safe to use Profen 400mg Tablet?

Profen 400mg Tablet is safe for most patients. However, in some patients, it may cause some unwanted side effects like nausea, vomiting, stomach pain, heartburn and diarrhea. Inform your doctor if you experience any persistent problem due to this medication.

Q. What should I tell my doctor before starting treatment with Profen 400mg Tablet?

Before starting treatment with Profen 400mg Tablet, tell your doctor if you have any other health problems, like kidney or liver-related issues. This is because certain medical conditions may affect your treatment and you may even need dose modifications. Let your doctor know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Inform your doctor if you are planning a baby, if you are pregnant or breastfeeding.

Q. What if I forget to take a dose of Profen 400mg Tablet?

If you forget a dose of Profen 400mg Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose in the prescribed time. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.

Q. Can I stop taking Profen 400mg Tablet when my pain is relieved?

Profen 400mg Tablet should be continued as advised by your doctor, if you are using the medicine for a condition associated with long-term pain. It can be discontinued if you are using it for short-term pain relief.

Q. Can the use of Profen 400mg Tablet cause nausea and vomiting?

Yes, the use of Profen 400mg Tablet may cause nausea and vomiting. Taking it with milk, food or antacids can prevent nausea. Avoid taking fatty or fried foods along with this medication. In case of vomiting, drink plenty of water or other fluids by taking small frequent sips. Talk to your doctor if vomiting persists and you notice signs of dehydration, like dark colored and strong-smelling urine or a low frequency of urination. Do not take any other medicines without speaking to your doctor.

Q. Are there any specific contraindications associated with the use of Profen 400mg Tablet?

The use of Profen 400mg Tablet is considered to be harmful for patients with known allergy to any of the components of this medicine. It should be avoided in patients with known allergy to other painkillers (NSAIDs). The use of this medicine should preferably be avoided in patients with a history of stomach ulcers or in patients with active or recurrent stomach ulcer/bleeding. It should also be avoided in patients with a history of heart failure, high blood pressure, and liver or kidney disease.

Q. Is Profen 400mg Tablet helpful in relieving stomach pain?

No, Profen 400mg Tablet should not be taken for stomach pain without consulting a physician. This drug can increase stomach acid secretion which may aggravate an unknown underlying condition.

Q. Can the use of Profen 400mg Tablet cause damage to kidneys?

Yes, the long-term use of Profen 400mg Tablet can cause damage to the kidneys. Normal kidneys produce a chemical called prostaglandins that protect the kidneys from damage. Use of painkillers lowers the levels of prostaglandins in the body, leading to kidney damage because of long-term use. Therefore, the use of painkillers is not recommended in patients with underlying kidney disease.

Q. Is it safe to take a higher than the recommended dose of Profen 400mg Tablet?

No, taking a higher than the recommended dose of Profen 400mg Tablet can increase the risks of side effects like nausea, vomiting, heartburn, indigestion and diarrhea. In fact, using this medicine for a long-term can also damage your kidneys on long-term use. If you are experiencing increased severity of pain or if the pain is not relieved by the recommended doses of this medicine, please consult your doctor for re-evaluation.

Q. Can Profen 400mg Tablet cause dizziness?

Yes, Profen 400mg Tablet can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, do not drive or use any machines. It is better to rest for sometime and resume once you feel better.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 627.
Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 988.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 682-84.
Drugs.com. Ibuprofen. [Accessed 02 Apr. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. Jornal de Pediatria. 2004; 80(5): 4-6. [Accessed 02 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:

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