Prothiaden Tablet
Prescription Required
Product introduction
Prothiaden Tablet is a tricyclic antidepressant. It is mostly used to treat depression that is unresponsive to alternative treatment. It is also used in the management of anxiety disorder.
Prothiaden Tablet works by increasing the levels of chemical messengers in the brain that stabilizes and enhances the mood. It is better to take it before bedtime because it can make you feel drowsy. It can be taken with or without food, but you should take it at a fixed time each day for better efficacy. The dose and duration will be decided by your doctor so that you get the right amount to control your symptoms. Do not skip any dose and finish the full course of treatment even if you feel better. This medication must not be stopped suddenly without talking to the doctor. Your dose may be modified or gradually decreased before stopping the medication.
The most common side effects of Prothiaden Tablet include increased heart rate, blurred vision, dryness in the mouth, and constipation. Initially, this medicine may also cause a sudden drop in blood pressure, especially when you change positions. It may even cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. It may also lead to weight gain in some people. Most of the common side effects tend to be mild and temporary. Your doctor may be able to suggest ways of preventing or reducing them. Serious side effects associated with this medicine are rare.
Before taking this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same or any other diseases. Pregnant and breastfeeding women should take this medicine with proper consultation and caution. This medicine is not known to be addictive, but you can experience additional side effects (withdrawal symptoms) if you stop taking it suddenly. If you notice any sudden mood change or get suicidal or self-harm thoughts, you must consult the doctor without delay. Also, remember to take this medicine strictly as advised by the doctor as an overdose of this medication may lead to a serious health emergency. Consumption of alcohol should strictly be avoided as alcohol interacts with this medicine to cause serious health issues.
Uses of Prothiaden Tablet
Benefits of Prothiaden Tablet
In Treatment of Anxiety disorder
Prothiaden Tablet is thought to work by stopping your brain from releasing the chemicals that make you feel anxious so it can reduce the symptoms of excessive anxiety and worry. It can also reduce feelings of restlessness, tiredness, difficulty concentrating, irritability, and sleep problems that often come with Generalised Anxiety Disorder. It will, therefore, help you go about your daily activities more easily and be more productive. Keep taking this medicine even if you feel well. Stopping suddenly can cause serious problems.
Side effects of Prothiaden Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Prothiaden
- Dryness in mouth
- Increased heart rate
- Orthostatic hypotension (sudden lowering of blood pressure on standing)
- Difficulty in urination
- Constipation
- Blurred vision
How to use Prothiaden Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Prothiaden Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Prothiaden Tablet works
Prothiaden Tablet is a tricyclic antidepressant. It increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.
Safety advice
Alcohol
UNSAFE
Prothiaden Tablet may cause excessive drowsiness with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
Prothiaden Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Prothiaden Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Prothiaden Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Prothiaden Tablet in patients with kidney disease. Please consult your doctor.
However, some studies suggest a cautious use of this medicine in patients with kidney disease.
However, some studies suggest a cautious use of this medicine in patients with kidney disease.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Prothiaden Tablet in patients with liver disease. Please consult your doctor.
What if you forget to take Prothiaden Tablet?
If you miss a dose of Prothiaden Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
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Quick tips
- It may take 4 to 6 weeks for Prothiaden Tablet to start working. Keep taking it as prescribed.
- It may cause sleepiness. Take it at bedtime and do not drive or do anything requiring concentration until you know how it affects you.
- Avoid consuming alcohol when taking Prothiaden Tablet as it may cause excessive sleepiness.
- Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
Fact Box
Chemical Class
Dibenzoxepin Derivative
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Tricyclic Antidepressants (TCAs)
Interaction with drugs
Taking Prothiaden with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concomitant use may cause a fatal increase in blood serotonin levels. Patients may experience agitation, increased body temperature, fast heartbeat, muscle rigidity, and loss of co
Concomitant use may cause an increase in blood serotonin levels. Patients may experience agitation, increased body temperature, fast heartbeat, muscle rigidity, and loss of coordin
Concomitant use may affect heart rhythm and can be fatal.
Do not consume Domperidone with Dosulepin.
Concurrent use may cause serotonin syndrome.
Careful consideration is advised if you have epilepsy. Watch out for symptoms of serotonin syndrome, such as sedation, respiratory imp
Concurrent use may cause serious disturbance in heart rhythm.
If concurrent use is essential, watch out for symptoms such as sleepiness, dry mouth, impaired voluntary movements, w
Patient concerns
User feedback
Patients taking Prothiaden Tablet
Once A Day
100%
What are you using Prothiaden Tablet for?
Anxiety disor*
60%
Others
29%
Neuropathic p*
8%
Depression
3%
*Anxiety disorder, Neuropathic pain
How much was the improvement?
Average
41%
Poor
33%
Excellent
26%
What were the side-effects while using Prothiaden Tablet?
No Side Effec*
38%
Dryness in mo*
22%
Weight gain
10%
Orthostatic h*
8%
Increased hea*
8%
*No Side Effect, Dryness in mouth, Orthostatic hypotension (sudden lowering of blood pressure on standing), Increased heart rate
How do you take Prothiaden Tablet?
With food
70%
With or witho*
30%
*With or without food
Please rate Prothiaden Tablet on price
Average
50%
Expensive
26%
Not Expensive
25%
FAQs
What is Prothiaden Tablet used for?
Prothiaden Tablet is a medicine used to treat anxiety disorder and depression that is unresponsive to other alternative medicines. It is also used to relieve nerve pain and fibromyalgia. Prothiaden Tablet should be taken only if prescribed by a doctor, exactly as directed.
Is Prothiaden Tablet a muscle relaxant?
No. Prothiaden Tablet is not a muscle relaxant. It is a tricyclic antidepressant (TCA) used in the treatment of depression, nerve pain, and anxiety disorder.
What is the difference between Prothiaden Tablet and amitriptyline?
Prothiaden Tablet is chemically related to Amitriptyline and both are tricyclic antidepressant (TCA) medicine. There is overlap in pharmacological property of this medicine.
Is Prothiaden Tablet the same as doxepin?
Prothiaden Tablet and doxepin are different medicines but belong to the similar chemical class. Doxepin, at low doses, can improve sleep in patients with insomnia. It is also available in the topical form for use in various neuro-dermatitis syndrome, especially itching.
How to stop Prothiaden Tablet?
If your doctor asks you to stop Prothiaden Tablet, you should reduce the dose slowly over 4 weeks. You should not discontinue it abruptly. Sudden discontinuation may cause aggression, anxiety, blurred vision, concentration impairment, constipation and crying spell.
Is Prothiaden Tablet fatal?
Yes. Prothiaden Tablet can be fatal (can cause death) in overdose. This is due to a life-threatening or dangerous side effect in overdose like hyperthermia, seizure, arrhythmia, tachycardia, orthostatic hypotension or sudden death. That's why it is generally not considered a first-line option for depression because of side effect profile.
Can I take Prothiaden Tablet with diazepam?
It is better to avoid this combination. Diazepam is a sedative drug and Prothiaden Tablet may cause sedation as a side effect too. Taking both of them together can increase the drowsiness or sleepiness. Inform your doctor if you are taking diazepam.
Can Prothiaden Tablet be used in the treatment of trigeminal neuralgia?
No. Prothiaden Tablet is not approved for the treatment of trigeminal neuralgia. Trigeminal neuralgia is a chronic pain condition that affects the trigeminal or 5th cranial nerve, one of the most widely distributed nerves in the head.
Can Prothiaden Tablet be used in the treatment of burning mouth syndrome?
No. Prothiaden Tablet is not approved for the treatment of burning mouth syndrome. Burning mouth syndrome is a painful condition of mouth that is burning, scalding, tingling or feeling of numbness that may occur every day for months or longer.
Can I take Prothiaden Tablet for depression?
Yes. Prothiaden Tablet is indicated for the treatment of depression. It has a potential advantage in the patient with depression if associated with insomnia and anxiety. It is generally not considered a first-line option for depression because of side effect profile but very useful for severe or treatment-resistant depression.
Can Prothiaden Tablet used to treat IBS (Irritable Bowel Syndrome)?
No. Prothiaden Tablet is not approved for the treatment of Irritable Bowel Syndrome (IBS). Irritable Bowel Syndrome is a functional gastrointestinal disorder characterised by chronic or recurrent abdominal pain or discomfort associated with altered bowel habits.
Can Prothiaden Tablet be used to treat insomnia with depression?
Yes. Prothiaden Tablet may be used for the treatment of insomnia (too much arousal both at night and during the day) associated with depression. Because it can cause drowsiness or sedation as side effects, it is effective in treating insomnia associated with depression.
Can I use Prothiaden Tablet for fibromyalgia?
Yes. Prothiaden Tablet is not approved for the treatment of fibromyalgia. Fibromyalgia is a pain syndrome with tenderness but no structural pathology in muscles, ligamanets or joints.
Can I use Prothiaden Tablet for nerve pain?
Yes. Prothiaden Tablet is indicated for the treatment of nerve pain/neuropathic pain. Chronic pain/Neuropathic pain is described as pain that arises from damage to, or dysfunction of, any part of peripheral or central nervous system. It is associated with the disease which can affect nerves like diabetes mellitus or herpes infections.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Stahl SM, editor. Dothiepin. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 205-10.
- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 20 Mar. 2019] (online) Available from:
- PubChem. Dothiepin. [Accessed 22 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:
- Dosulepin [Package Insert]. Debrecen, Hungary: TEVA Pharmaceutical Work Private Limited; 2021. [Accessed 25 Jul. 2024] (online) Available from:
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