Prothymo 450mg Tablet is used to treat cytomegalovirus (CMV) infection of the retina (retinitis) in adult patients with acquired immunodeficiency syndrome (AIDS). It is also used for the prevention of CMV infection in patients who have received an organ transplant from a CMV-infected donor.

Prothymo 450mg Tablet should be taken in the dose and duration as advised by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. It should be taken with food. If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose. You should drink plenty of water while on treatment with this medicine as it helps to prevent dehydration and kidney damage.

It may lead to a few common side effects like fever, diarrhea, vomiting, anemia, low white blood cell, and low platelet level. Inform your doctor if these side effects persist for a longer duration. Please consult your doctor if you are pregnant, planning to conceive or breastfeeding.

Uses of Prothymo Tablet

Treatment of Cytomegalovirus Infection

Benefits of Prothymo Tablet

In Treatment of Cytomegalovirus Infection

Cytomegalovirus infection is a common virus infection which may have no symptoms at all or may have symptoms like fever and fatigue. Severe infection may show symptoms involving the eyes, brain, or other internal organs. This virus is spread through sexual and nonsexual contact with body secretions in people who are immunocompromised or those who have undergone any transplant. Prothymo 450mg Tablet helps to prevent multiplication of the infection causing virus and treats the infection. Keep taking it in the dose and duration prescribed by the doctor to get maximum benefit.

Side effects of Prothymo Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Prothymo

Diarrhea
Fever
Vomiting
Anemia (low number of red blood cells)
Decreased white blood cell count
Low blood platelets
Insomnia (difficulty in sleeping)
Tremors

How to use Prothymo Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Prothymo 450mg Tablet is to be taken with food.

How Prothymo Tablet works

Prothymo 450mg Tablet is an antiviral medication. It prevents the multiplication of virus in human cells. This stops the virus from producing new viruses and clears up your infection.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Prothymo 450mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Prothymo 450mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Prothymo 450mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Prothymo 450mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Prothymo 450mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Prothymo 450mg Tablet may be needed. Please consult your doctor.

Liver

SAFE IF PRESCRIBED

Prothymo 450mg Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Prothymo 450mg Tablet may not be needed in these patients. Please consult your doctor.

What if you forget to take Prothymo Tablet?

If you miss a dose of Prothymo 450mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Prothymo 450mg Tablet

₹423.5/Tablet

Valgan Tablet

Cipla Ltd

₹300.5/tablet

29% cheaper

Cymgal Tablet

Eris Lifesciences Ltd

₹416.5/tablet

2% cheaper

Valchek Tablet

La Renon Healthcare Pvt Ltd

₹396.5/tablet

6% cheaper

Valniche 450 Tablet

Alniche Life Sciences Pvt Ltd

₹421/tablet

1% cheaper

Valgaids Tablet

Jolly Pharma

₹297.25/tablet

30% cheaper

View all substitutes

Fact Box

Chemical Class

Nucleoside analog

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Action Class

Antiviral (Non-HIV) drugs

Interaction with drugs

Taking Prothymo with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Tacrolimus (Oral Route) Severe

Concurrent use may increase the risk of kidney damage. If concurrent use is essential, your doctor may monitor your tacrolimus levels, potassium levels and kidney function closely... More

Tenofovir disoproxil fumarate (Oral Route) Severe

Concurrent use may increase the risk of kidney damage. If concurrent use is essential, your doctor may monitor your kidney's functioning closely.

Amphotericin B (Vaginal Route) Moderate

Amphotericin B may slow down the removal of Valganciclovir from the body. If concurrent use is essential, please consult your doctor. They may monitor your kidney's functioning cl... More

Co-trimoxazole (Oral Route) Moderate

Concurrent use may increase the risk of low blood cell counts. Do not consume Valganciclovir with Co-trimoxazole. If concurrent use is essential, your doctor may monitor your bloo... More

Cidofovir (Injection Route) Moderate

Cidofovir may slow down the removal of Valganciclovir from the body. If concurrent use is essential, please consult your doctor. They may monitor your kidney's functioning closely... More

View all drug interactions

Patient concerns

i have unprotected sex with my friend. Can I take any drugs now to prevent any STD/HIV infection

Dr. Shyam Gupta

Obstetrics and Gynaecology

Hello PATIENT to 1mg. There is some medicine for prophylactic but you need to see physician for prescription and better you check HIV status of both partner

hello, one of my frnd suffering with hiv infection from last 2yrs her cd4 is more than 470 and viral load is zero undetectable now she is using art medicines i have doubt that can we have to use art medicine in the whole life or can we stop it once we get viral load zero

Dr. Atula Gupta

Dermatology

You still need to be on ART even if the viral load is undetectable

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FAQs

What is valganciclovir used for?

Valganciclovir is used for the treatment of cytomegalovirus (CMV) infection of retina (retinitis) in adult patients with acquired immunodeficiency syndrome (AIDS). It is also used for the prevention of CMV infection in patients who have received an organ transplant from a CMV-infected donor

How does valganciclovir work?

After taken orally, valganciclovir gets converted into ganciclovir by liver and intestinal enzymes, which then prevents the growth and spread of cytomegalovirus.

Is valganciclovir cytotoxic?

No, valganciclovir is not cytotoxic

Does valganciclovir cover HSV?

Valganciclovir can also be used for treatment of herpes simplex virus (HSV) infection. Please follow doctor's advice regarding its use

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Acosta EP, Flexner C. Antiviral Agents (Nonretroviral). In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1603-605.
Safrin S. Antiviral Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 852.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1446-47.
Valgaciclovir. Grenzach-Wyhlen, Germany: Roche Pharma; 2018. [Accessed 01 Apr. 2019] (online) Available from:
Valganciclovir hydrochloride. Garden City, Hertfordshire: Roche Products Limited; 2002 [revised 16 May 2018]. [Accessed 28 Jan. 2019] (online) Available from:
Valganciclovir. South san Francisco, California: Genentech USA; 2001 [revised Aug. 2010]. [Accessed 01 Apr. 2019] (online) Available from:
CiplaMed. Valganciclovir [Prescribing Information]. [Accessed 07 Aug. 2023]. (online) Available from:

Marketer details

Name: Sanofi India Ltd

Address: Sanofi House, CTS No.117-B, L&T Business Park, Saki Vihar Road, Powai, Mumbai 400072

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.