Protome Plus Tablet is a pain-relieving medicine. It helps in relieving moderate pain and reducing fever. It is used in various conditions such as muscle ache, back pain, joint pain, menstrual cramps, and toothache.
Protome Plus Tablet should be taken with food. This will prevent you from getting an upset stomach. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. You should keep taking the medicine even if you feel better until the doctor says it is alright to stop using it.
Using this medicine may cause few common side effects such as nausea, vomiting, headache, vertigo, stomach pain, indigestion, and heartburn. If you experience any such side effects that do not go away or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms. In general, you should try to use the smallest amount necessary to control your symptoms.
Before using the medicine, you should tell your doctor if you have any other medical conditions or disorders. It may also affect, or be affected by, some other medicines you are using so let your doctor know all the other medicines you are taking. It should be used with caution in patients who are alcoholic or have liver or kidney disease. Pregnant and breastfeeding women should consult their doctors first before using the medicine.
Protome Plus Tablet is a combination of medicines that is used for short term relief of pain, inflammation and swelling. It inhibits release of those chemical messengers in the brain that tell us that we have pain. It effectively relieves back pain, earache, throat pain, toothache, periods pain and pain due to arthritis too. Take Protome Plus Tablet as prescribed by the doctor to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.
Side effects of Protome Plus Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Protome Plus
Nausea
Vomiting
Stomach pain
Indigestion
Heartburn
Loss of appetite
Diarrhea
Headache
Vertigo
Increased liver enzymes
How to use Protome Plus Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Protome Plus Tablet is to be taken with food.
How Protome Plus Tablet works
Protome Plus Tablet is a combination of three medicines: Diclofenac, Paracetamol and Serratiopeptidase, which relieves pain. Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) and Paracetamol is an antipyretic (fever reducer). They work by blocking the release of certain chemical messengers in the brain that cause pain and fever. Serratiopeptidase is an enzyme which works by breaking down abnormal proteins at the site of inflammation, and promotes healing.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Protome Plus Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Protome Plus Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Protome Plus Tablet during breastfeeding is not available. Please consult your doctor.
Driving
UNSAFE
Protome Plus Tablet may cause side effects which could affect your ability to drive. Protome Plus Tablet may cause headaches, blurred vision, dizziness or drowsiness in some patients. This may affect your ability to drive.
Kidney
CAUTION
Protome Plus Tablet should be used with caution in patients with kidney disease. Dose adjustment of Protome Plus Tablet may be needed. Please consult your doctor.
Liver
CAUTION
Protome Plus Tablet should be used with caution in patients with liver disease. Dose adjustment of Protome Plus Tablet may be needed. Please consult your doctor. However, the use of Protome Plus Tablet is not recommended in patients with severe liver disease and active liver disease.
What if you forget to take Protome Plus Tablet?
If you miss a dose of Protome Plus Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
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What are the storage condition for Protome Plus Tablet?
Keep this medicine in the container or the pack it came in, tightly closed. Store it as mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
What is Protome Plus Tablet?
Protome Plus Tablet is a combination of three medicines: Diclofenac, Paracetamol, and Serratiopeptidase. This medication helps in relieving pain and inflammation. It works by lowering the levels of chemical substances in the body that causes pain and inflammation.
Is it safe to use Protome Plus Tablet?
Yes, Protome Plus Tablet is safe for most of the patients, however, in some patients it may cause common unwanted side effects like nausea, vomiting, stomach pain, heartburn and diarrhea. Inform your doctor as soon as possible if you experience any persistent problem due to the medication.
Can I stop taking Protome Plus Tablet when my pain is relieved?
Protome Plus Tablet is usually used for a short term and can be discontinued when the pain is relieved. However, Protome Plus Tablet should be continued if you are advised by your physician to do so.
Can the use of Protome Plus Tablet cause nausea and vomiting?
Yes, the use of Protome Plus Tablet can cause nausea and vomiting.Taking it with milk, food or with antacids can prevent nausea. Avoid taking fatty or fried foods along with this medication. In case of vomiting, drink plenty of water or other fluids by taking small frequent sips. Talk to your doctor if vomiting persists and you notice signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicine without speaking to your doctor.
Can the use of Protome Plus Tablet cause dizziness?
Yes, the use of $ame can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for sometime and resume once you feel better. Do not drive or use any machines.
Are there any specific contraindications associated with the use of Protome Plus Tablet?
The use of Protome Plus Tablet is considered to be harmful for patients with known allergy to any of the components or excipients of this medicine or in patients with known allergy to other painkillers (NSAIDs). The use of this medicine should preferably be avoided in patients with a history of stomach ulcers or in patients with active, recurrent stomach ulcer/bleeding. It should also be avoided in patients with a history of heart failure, high blood pressure, and liver or kidney disease.
Can I take Protome Plus Tablet with Vitamin B-complex?
Protome Plus Tablet can be taken with Vitamin B-complex preparations. While Protome Plus Tablet helps to relieve pain, Vitamin B-complex can help to correct the vitamin deficiency that might be causing your symptoms.
Can I take Protome Plus Tablet for stomach pain?
No, Protome Plus Tablet preferably should not be taken for stomach pain without consulting a physician. This drug can increase stomach acid secretion which may aggravate an unknown underlying condition.
Can the use of Protome Plus Tablet cause damage to kidneys?
No, taking higher than the recommended dose of Protome Plus Tablet can lead to increased chances of side effects. If you are experiencing increased severity of pain or if the pain is not relieved by the recommended doses, please consult your doctor for re-evaluation.
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Bhagat S, Agarwal M, Roy V. Serratiopeptidase: A systematic review of the existing evidence. Int J Surg. 2013;11(3):209-17. [Accessed 19 Apr. 2019] (online) Available from:
Diclofenac Sodium and Paracetamol [Patient Information Sheet]. Gangtok, Sikkim: Torrent Pharmaceuticals Ltd.; 2022. [Accessed 21 Aug. 2024] (online) Available from:
The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.