Pynole 2mg Oral Drops is a medicine given to children to help treat nausea and vomiting. It is mainly given to treat nausea and vomiting associated with surgery, chemotherapy, radiotherapy, and stomach/intestinal infection. It also helps treat vomiting that is caused as a side effect of medicines like painkillers.

Pynole 2mg Oral Drops may be given before or after meals. To control vomiting caused due to chemotherapy, give this medicine to your child 30 minutes before the procedure. Give it 1 to 2 hours before a radiotherapy session and 1 hour before surgery to prevent your child from vomiting post these procedures. If your child expels out the medicine within 30 minutes of the intake, help your child calm down and repeat the dose. Do not double dose if it is already time for the next dose.

Pynole 2mg Oral Drops may cause some temporary side effects such as headache, constipation, diarrhea, and fatigue. These side effects usually subside once your child’s body adapts to the medicine. In case these side effects persist or become bothersome, do reach out to the doctor on a priority basis.

Let the doctor know about all the medicines your child is taking, including painkillers, antibiotics, or medicines taken to treat depression. Also, inform the doctor if your child has a history of liver problems, kidney malfunction, blockage in the gastrointestinal tract, heart problems, or allergies to any medicine, its ingredients, or a food product. This information is very important for dose alterations and for planning your child’s overall treatment.

Uses of Pynole 2mg Oral Drops in children

Side effects of Pynole 2mg Oral Drops in children

Pynole 2mg Oral Drops does not pose serious side effects and is well-tolerated by children. In case the side effects do occur, they’re likely to subside once the body adapts to the medicine. Consult your child’s doctor if these side effects persist or bother your child. The most common side effects include-

Common side effects of Pynole

Constipation
Diarrhea
Fatigue
Headache

How can I give Pynole 2mg Oral Drops to my child?

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a marked dropper and take it as directed. Pynole 2mg Oral Drops may be taken with or without food, but it is better to take it at a fixed time.

How Pynole Oral Drops works

During radiotherapy, chemotherapy, abdominal infection, or any major surgeries, the dead cells in the body start releasing a chemical called serotonin directly into the blood. Later, this stimulates special centers in the body that are responsible for inducing vomiting in your child. Giving Pynole 2mg Oral Drops just before the procedure helps block the effect of this chemical on vomiting centers of the brain and prevents vomiting.

Safety advice

Kidney

SAFE IF PRESCRIBED

Pynole 2mg Oral Drops is safe to use in patients with kidney disease. No dose adjustment of Pynole 2mg Oral Drops is recommended.

Liver

CAUTION

Pynole 2mg Oral Drops should be used with caution in patients with liver disease. Dose adjustment of Pynole 2mg Oral Drops may be needed. Please consult your doctor.
In severe liver disease, do not exceed the prescribed dose and consult your child’s doctor.

What if I forget to give Pynole 2mg Oral Drops to my child?

Do not panic. Give the missed dose as soon as you remember. However, you must skip the missed dose if it’s almost time for the next dose. Do not give a double dose and follow the prescribed dosing schedule.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Pynole 2mg Oral Drops

₹33.9/Oral Drops

Ondy Oral Drops

Ronyd Healthcare Pvt Ltd

₹42/oral drops

20% costlier

Onzy Oral Drops

Hauz Pharma Pvt Ltd

₹29/oral drops

17% cheaper

Ondocas 2mg Oral Drops

Medicasa Pharmaceutical

₹32/oral drops

9% cheaper

Ondex 2mg Oral Drops

Capri Pharmaceuticals

₹32/oral drops

9% cheaper

P-Norm Oral Drops

Panm Labs India

₹33/oral drops

6% cheaper

View all substitutes

Quick tips

Pynole 2mg Oral Drops effectively controls nausea and bouts of vomiting reflex in children undergoing chemotherapy or radiotherapy sessions.
It is fast-acting and starts working within 30 minutes.
Practice self-care measures:
1. Give plenty of fluids to your child to avoid dehydration
2. Avoid giving fried and spicy food or heavy meals to your child.
3. Ensure that your child eats slowly and in small proportions.

Fact Box

Chemical Class

Carbazole Derivative

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Action Class

Serotonin 5-HT3 Receptor Antagonists

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FAQs

What is Pynole 2mg Oral Drops used for?

Pynole 2mg Oral Drops is generally given before any major surgery or before chemotherapy and radiotherapy sessions. In case your child is about to undergo any of the above procedures, the doctor may ask you to give Pynole 2mg Oral Drops to your child to prevent vomiting post-procedure. Apart from this, Pynole 2mg Oral Drops is also found useful in treating vomiting caused due to diseases of the stomach. In such a case, your child’s doctor may prescribe giving Pynole 2mg Oral Drops to your child for a few days. Stick to the dose for best results.

What if my child takes too much Pynole 2mg Oral Drops?

Pynole 2mg Oral Drops is unlikely to cause harm if you give an extra dose by mistake. However, you must still speak to your child’s doctor immediately. Sometimes, excessive intake of Pynole 2mg Oral Drops can cause some serious side effects like excess sleepiness, agitation, rapid heartbeat, hypertension, flushing, dilated pupils, sweating, involuntary muscle jerk, uncontrolled eye movements, overactive reflexes, and seizures. These symptoms are collectively known as serotonin syndrome. If any of these appear, consult the doctor without any delay.

How should Pynole 2mg Oral Drops be stored?

Pynole 2mg Oral Drops should be stored at room temperature, in a dry place, away from direct heat and light. Also, keep all the medicines out of the reach and sight of children to avoid any accidental intake.

Can other medicines be given at the same time as Pynole 2mg Oral Drops?

Pynole 2mg Oral Drops can sometimes interact with other medicines or substances. Tell your doctor about any other medicines your child is taking before starting Pynole 2mg Oral Drops. Also, check with your child’s doctor before giving any medicine to your child.

In what conditions do I need to call my child’s doctor right away?

Call your child’s doctor immediately if your child develops symptoms of serotonin syndrome like irregular heartbeat, green-colored vomiting, inability to pass wind, pale skin and eyes, dark-colored urine, restlessness, and insomnia.

My child is having a migraine and is on medication. Can I give Pynole 2mg Oral Drops along with it?

Avoid combining Pynole 2mg Oral Drops with such medicines because concomitant use of Pynole 2mg Oral Drops with medicines meant to treat depression or migraine results in serotonin syndrome. Consult your child’s doctor before giving any medicine to your child.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

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Katzung BG. Histamine, Serotonin, & the Ergot Alkaloids. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 285
Ondansetron hydrochloride [FDA Label]. Research Triangle Park, NC: GlaxoSmithKline; 2016. [Accessed 04 Jan. 2020] (online) Available from:
Children’s Minnesota. Patient & Family Education Materials: Ondansetron (Zofran). [Accessed 04 Jan. 2020] (online) Available from:
Ondansetron [Summary of Product Characteristics]. Solan, Himachal Pradesh: Cachet Pharmaceuticals PVT. LTD.; 2024. [Accessed 25 Jul. 2024] (online) Available from:

Marketer details

Name: Parul Health Care Private Limited

Address: 29, Rajinder Nagar, Dc Colony Karnal, Hr 132001 India

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.