Pyregesica Tablet is a pain-relieving medicine. It is used to reduce pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It may also be used to relieve muscle pain, back pain, toothache, or pain in the ear and throat.

Pyregesica Tablet should be taken with or without food. You should take it regularly as advised by your doctor. Your doctor may change the dose and time between doses according to your pain level and your needs. Do not take more or use it for a longer duration than recommended by your doctor.

Some of the common side effects of this medicine include nausea, vomiting, stomach pain, heartburn, and diarrhea. If any of these side effects bother you or do not go away with time, you should let your doctor know. Your doctor may help you with ways to reduce or prevent these side effects by prescribing an alternative medicine or adjusting the dose.

Pyregesica Tablet may not be suitable for everybody. Before taking it, let your doctor know if you have any problems with your heart, kidneys, liver, or have stomach ulcers. To make sure it is safe for you, let your doctor know about all the other medicines you are taking. Pregnant and breastfeeding mothers should first consult their doctors before using Pyregesica Tablet.

Uses of Pyregesica Tablet

Pain relief

Benefits of Pyregesica Tablet

In Pain relief

Pyregesica Tablet is used for short-term relief of pain, inflammation, and swelling in conditions that affect joints and muscles. Some of the conditions in which Pyregesica Tablet is used are rheumatoid arthritis, osteoarthritis, muscle pain, back pain, toothache, or pain in the ear and throat. Take it as it is prescribed to get the most benefit. Do not take more or longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.

Side effects of Pyregesica Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pyregesica

Nausea
Vomiting
Stomach pain/epigastric pain
Heartburn
Diarrhea

How to use Pyregesica Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pyregesica Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Pyregesica Tablet works

Pyregesica Tablet is a combination of two medicines: Aceclofenac and Paracetamol. These medicines work by blocking the action of chemical messengers responsible for pain, fever and inflammation (redness and swelling).

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Pyregesica Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Pyregesica Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Pyregesica Tablet during breastfeeding is not available. Please consult your doctor.

Driving

UNSAFE

Pyregesica Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Pyregesica Tablet should be used with caution in patients with kidney disease. Dose adjustment of Pyregesica Tablet may be needed. Please consult your doctor.
Use of Pyregesica Tablet is not recommended in patients with severe kidney disease.

Liver

CAUTION

Pyregesica Tablet should be used with caution in patients with liver disease. Dose adjustment of Pyregesica Tablet may be needed. Please consult your doctor.
However, the use of Pyregesica Tablet is not recommended in patients with severe liver disease and active liver disease.

What if you forget to take Pyregesica Tablet?

If you miss a dose of Pyregesica Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Pyregesica Tablet

₹4.85/Tablet

Dolokind Plus Tablet

Mankind Pharma Ltd

₹4.33/tablet

11% cheaper

Acimol 100 mg/325 mg Tablet

Leeford Healthcare Ltd

₹2.7/tablet

44% cheaper

Vetory P Tablet

Hetero Drugs Ltd

₹2.9/tablet

40% cheaper

Zerodol P Tablet

Ipca Laboratories Ltd

₹7/tablet

44% costlier

Zulu-P Tablet

Torrent Pharmaceuticals Ltd

₹7.1/tablet

46% costlier

View all substitutes

Quick tips

You have been prescribed this combination medicine for relieving pain and inflammation.
Take Pyregesica Tablet it with food to avoid getting an upset stomach.
Do not take Pyregesica Tablet with any other medicine containing paracetamol (drugs for pain/fever or cough-and-cold) without asking your doctor first.
It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
Avoid consuming alcohol when taking Pyregesica Tablet as it may cause excessive drowsiness and increase the risk of liver damage.
In case of muscle pain, your doctor might advise you to undergo physiotherapy to get relief along with taking Pyregesica Tablet.
Inform your doctor if you have a history of stomach ulcers before taking this medicine.

Fact Box

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Patient concerns

One of my teeth is sensitive. It some times pains

Dr. Abhijit Gambhir

Dental Surgery

sensitivity has many causative factors for relief of pain you can take pain killers it will give temporary relief

fever and 2 months pregnant can take combiflan

Dr. Sonu Balhara Ahlawat

Obstetrics and Gynaecology

No take Crocin for pain relief

User feedback

Patients taking Pyregesica Tablet

Once A Day

67%

Twice A Day

33%

What are you using Pyregesica Tablet for?

Headache

50%

Fever

50%

How much was the improvement?

Excellent

100%

What were the side-effects while using Pyregesica Tablet?

No Side Effec*

100%

*No Side Effect

FAQs

What is Pyregesica Tablet?

Pyregesica Tablet is a combination of two medicines: Aceclofenac and Paracetamol. This medication helps in relieving pain and inflammation. It works by lowering the levels of chemical substances in the body that cause pain and inflammation.

Is it safe to use Pyregesica Tablet?

Pyregesica Tablet is safe for most of the patients. However, in some patients it may cause some unwanted common side effects like nausea, vomiting, stomach pain, heartburn, diarrhea and other uncommon and rare side effects.

Can I stop taking Pyregesica Tablet when my pain is relieved?

If you are using the medication for a condition associated with long-term pain then Pyregesica Tablet should be continued for as long as advised by your physician. It can be discontinued if you are using it for short-term pain relief.

Can the use of Pyregesica Tablet cause nausea and vomiting?

Yes, the use of Pyregesica Tablet can cause nausea and vomiting. Taking it with milk, food or with antacids can prevent nausea. Avoid taking fatty or fried foods along with this medication. In case of vomiting drink plenty of water or other fluids by taking small frequent sips. Talk to your doctor if vomiting persists and you notice signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicine without speaking to your doctor.

Can the use of Pyregesica Tablet cause dizziness?

Yes, the use of Pyregesica Tablet can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for sometime and resume once you feel better.

Are there any specific contraindications associated with the use of Pyregesica Tablet?

The use of Pyregesica Tablet is considered to be harmful for patients with known allergy to any of the components or excipients of this medicine or in patients with known allergy to other painkillers (NSAIDs). It should preferably be avoided in patients with a history of stomach ulcers or in patients with active, recurrent stomach ulcer/bleeding. It should also be avoided in patients with a history of heart failure, high blood pressure, and liver or kidney disease.

Can Pyregesica Tablet be taken with vitamin B-complex?

Yes, Pyregesica Tablet can be taken with vitamin B-complex preparations. While Pyregesica Tablet helps to relieve pain, vitamin B-complex can help to correct the vitamin deficiency that might be causing the underlying painful condition.

Is Pyregesica Tablet helpful in relieving stomach pain?

No, Pyregesica Tablet preferably should not be taken for stomach pain without consulting a physician. This drug can increase stomach acid secretion which may aggravate an unknown underlying condition.

Can the use of Pyregesica Tablet cause damage to kidneys?

Yes, the long-term use of Pyregesica Tablet can cause damage to the kidneys. Normal kidneys produce a chemical messenger called prostaglandins that protects them from damage. Use of painkillers lowers the levels of prostaglandins in the body which leads to kidney damage on long-term use. Use of painkillers is not recommended to patients with underlying kidney disease.

Is it safe to take a higher dose of Pyregesica Tablet than recommended?

No, taking higher than the recommended dose of Pyregesica Tablet can lead to increased chances of side effects like nausea, vomiting, heartburn, indigestion, diarrhea and can also damage your kidneys on long-term use. If you are experiencing increased severity of pain or if the pain is not relieved by the recommended doses of this medicine, please consult your doctor for re-evaluation.

What are the instructions for storage and disposal of Pyregesica Tablet?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

How long does it take for Pyregesica Tablet to show results?

The effect of Pyregesica Tablet can be seen within 1.5 to 3 hours of oral administration of the medicine and the time taken to show the desired effects may vary with every individual patient.

What is the dosage of Pyregesica Tablet?

You may take one tablet of Pyregesica Tablet twice daily or as prescribed by your doctor. Always follow your doctor’s instructions while taking this medicine.

Can I take Pyregesica Tablet along with other painkiller tablets?

No, it is not recommended to take Pyregesica Tablet with other painkiller medicines without consulting your doctor since it may cause unwanted side effects like stomach pain or ulcers.

Can Pyregesica Tablet be given to children?

No, Pyregesica Tablet is not recommended for use in children under the age of 18 years.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Furst DE, Ulrich RW, Prakash S, et al. Nonsteroidal Anti-Inflammatory Drugs, Disease-Modifying Antirheumatic Drugs, Nonopioid Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ (Editors). Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 621-642.
Grosser T, Smyth EM, FitzGerald GA. Pharmacotherapy of Inflammation, Fever, Pain, and Gout. In: Brunton LL, Hilal-Dandan R, Knollmann BC (Editors). Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 13th ed. New York, NY: McGraw-Hill Education; 2018. pp. 685-709.
Eraas International. Aceclofenac+Paracetamol [Product Information]. [Accessed 14 Aug. 2024] (online) Available from:

Marketer details

Name: East India Pharmaceutical Works Ltd

Address: 6, NANDALAL BOSE SARANI,KOLKATA -700071

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.