Author Details
Written By
MDS, BDS
Reviewed By
MBA, MD Pharmacology
Last updated
09 Nov 2024 | 01:01 AM (IST)

We provide you with authentic, trustworthy and relevant information

Want to know more

Have issue with the content?

Report Problem

Pyril D Plus 20mg/650mg Tablet


Product introduction

Pyril D Plus 20mg/650mg Tablet is a prescription medicine used in the treatment of migraine. It prevents pain signals to reach the brain to reduce pain. It also blocks certain substances in the brain that trigger nausea or vomiting during migraine headaches.

Pyril D Plus 20mg/650mg Tablet is taken without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effect is dryness in mouth. This is temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about these side effects. Migraine attacks can be managed by identifying migraine-causing triggers which may be red wine, caffeine withdrawal, stress, and skipped meals, etc. You can identify personal triggers by maintaining a diary of what you are doing, what you are eating, and any stressful activity happened before migraine attack.

Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy or breastfeeding. You should tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you.

Uses of Pyril-D Tablet

Benefits of Pyril-D Tablet

In Treatment of Migraine

Pyril D Plus 20mg/650mg Tablet is a combination of medicines that helps prevent migraine by changing the way that your nerves receive pain signals. It also blocks the action of chemicals in the body that can make you feel or be sick. This treats as well as prevents nausea or vomiting effectively. By preventing and reducing the frequency of headaches, it can help you carry out your daily activities and have a better quality of life.

Side effects of Pyril-D Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pyril-D

  • Dryness in mouth

How to use Pyril-D Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pyril D Plus 20mg/650mg Tablet is to be taken empty stomach.

How Pyril-D Tablet works

Pyril D Plus 20mg/650mg Tablet is a combination of two medicines: Domperidone and Paracetamol. Domperidone is a prokinetic which works on the region in the brain that controls vomiting. It also increases the movement of the stomach and intestines, allowing food to move more easily through the stomach. This prevents nausea and vomiting caused due to migraine. Paracetamol is an analgesic (pain reliever) and an anti-pyretic (fever reducer) which blocks the release of certain chemical messengers that cause pain and fever associated with migraine.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Pyril D Plus 20mg/650mg Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Pyril D Plus 20mg/650mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Pyril D Plus 20mg/650mg Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
Pyril D Plus 20mg/650mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Pyril D Plus 20mg/650mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Pyril D Plus 20mg/650mg Tablet may be needed. Please consult your doctor.
Liver
CAUTION
Pyril D Plus 20mg/650mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Pyril D Plus 20mg/650mg Tablet may be needed. Please consult your doctor.
However, the use of Pyril D Plus 20mg/650mg Tablet is not recommended in patients with severe liver disease and active liver disease.

What if you forget to take Pyril-D Tablet?

If you miss a dose of Pyril D Plus 20mg/650mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Pyril D Plus 20mg/650mg Tablet
₹6.47/Tablet
Peredom 20 mg/650 mg Tablet
Med Manor Organics Pvt Ltd
₹9.4/tablet
45% costlier
Paragis D Tablet
Aigis Biotec
₹6.52/tablet
1% costlier

Quick tips

  • Pyril D Plus 20mg/650mg Tablet helps to ease the pain you feel during a migraine headache as well as helps to stop you from feeling sick.
  • Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.
  • Inform your doctor if you are taking any pain relief medicine.
  • Pyril D Plus 20mg/650mg Tablet can only decrease the number and severity of attacks but may not completely stop them.
  • Some tips that may help avoid a migraine attack:
    1. Have your meals at the same time every day.
    2. Avoid bright lights and extreme temperatures.
    3. Avoid loud music and noisy places.
    4. Avoid chocolates,  cheese, processed food, alcohol, and smoking.
    5. Get sufficient sleep and avoid stress.
  • Pyril D Plus 20mg/650mg Tablet helps to ease the pain you feel during a migraine headache as well as helps to stop you from feeling sick.
  • Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.
  • Inform your doctor if you are taking any pain relief medicine.
  • Pyril D Plus 20mg/650mg Tablet can only decrease the number and severity of attacks but may not completely stop them.
  • Some tips that may help avoid a migraine attack:
    1. Have your meals at the same time every day.
    2. Avoid bright lights and extreme temperatures.
    3. Avoid loud music and noisy places.
    4. Avoid chocolates,  cheese, processed food, alcohol, and smoking.
    5. Get sufficient sleep and avoid stress.

Fact Box

Habit Forming
No
Therapeutic Class
NEURO CNS

Patient concerns

arrow
I have fever with 3 days with nausea. headache .joint pain and loss of apettite. Weakness
Dr. Pushkar Mani
Physician
dolokind plus & omez d 20mg twice daily for 3 days
Rabi plus d and raberite d are same for back pain ??
Dr. Mehtab Baig
Orthopaedic Physiotherapy
Don't know bro.
arrow

FAQs

What is Pyril D Plus 20mg/650mg Tablet?

Pyril D Plus 20mg/650mg Tablet is a combination of two medicines: Domperidone and Paracetamol/Acetaminophen. Domperidone helps to control vomiting. It also increases the movement of the stomach and intestines, allowing food to move more easily through the stomach. This prevents nausea and vomiting caused due to migraine. Paracetamol/Acetaminophen is an analgesic (pain reliever) and an anti-pyretic (fever reducer) which blocks the release of certain chemical messengers that cause pain and fever associated with migraine.

Can I take a higher than the recommended dose of this medicine?

No, taking a higher than the recommended dose of Pyril D Plus 20mg/650mg Tablet can increase the risks of side effects and liver damage. If you are experiencing increased severity of symptoms that are not relieved by the recommended doses, please consult your doctor for re-evaluation.

Can I get addicted to Pyril D Plus 20mg/650mg Tablet?

No, there is no report of any patient getting addicted to Pyril D Plus 20mg/650mg Tablet.

Can the use of Pyril D Plus 20mg/650mg Tablet cause damage to liver?

Yes, Pyril D Plus 20mg/650mg Tablet can cause harm to the liver especially in the doses above the recommended level. Also, avoid drinking alcohol while taking this medicine, as it may further increase your risk of liver damage. Use of this medicine should preferably be avoided in patients with the underlying liver disease.

What is the recommended storage condition for the Pyril D Plus 20mg/650mg Tablet?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Want to share the information?

Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Domperidone maleate. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2003 [revised 14 Nov. 2017]. [Accessed 15 Apr. 2019] (online) Available from:External Link
  2. ScienceDirect. Domperidone. [Accessed 15 Apr. 2019] (online) Available from:External Link
  3. Drugs.com. Paracetamol. [Accessed 15 Apr. 2019] (online) Available from:External Link

Marketer details

Name: Dynamed Pharmaceuticals Pvt Ltd
Address: Dynamed Pharmaceuticals, No. 11-13-891/A, Road No. 2, Green Hills Colony, Hyderabad - 500035, Telangana, India
Country of origin: India
Expires on or after: February, 2025

A licensed vendor partner from your nearest location will deliver Pyril D Plus 20mg/650mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

54.9965.5Get 16% OFF
52.41+ free shipping withCare Plan Logo
Inclusive of all taxes
This offer price is valid on orders above ₹2500. Apply coupon HEALTHALL on the cart. Max. coupon discount is ₹400. T&C apply.
10.0 tablets in 1 strip
Add to cart
Cash on delivery available
Get it delivered by Tomorrow
Delivering to:
122019, GurgaonDown Arrow Icon

Additional offers

Airtel Payments Bank: Pay with Airtel Payments Bank and get 10% cashback up to Rs. 200 cashback on a minimum transaction of ₹1000. Valid only for first-time users for Airtel Payments Bank Savings Bank accounts.
Show more show_more

INDIA’S LARGEST HEALTHCARE PLATFORM

260m+
Visitors
31m+
Orders Delivered
1800+
Cities
Get the link to download App
Reliable

All products displayed on Tata 1mg are procured from verified and licensed pharmacies. All labs listed on the platform are accredited

Secure

Tata 1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant

Affordable

Find affordable medicine substitutes, save up to 50% on health products, up to 80% off on lab tests and free doctor consultations.

LegitScript approved
India's only LegitScript and ISO/ IEC 27001:2022 certified online healthcare platform

Know more about Tata 1mgdownArrow

Access medical and health information

Tata 1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

Order medicines online

Get free medicine home delivery in over 1800 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on Tata 1mg are procured from verified and licensed pharmacies.

Book lab tests

Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

Consult a doctor online

Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.