Ranolane 500mg Tablet ER is used for the management of angina (heart-related chest pain). It helps to prevent new attacks of angina but does not stop an acute attack, once started. It relieves chest pain by making the heart work more efficiently.

Ranolane 500mg Tablet ER should be taken in the dose as advised by your doctor, at the same time each day. It should be taken with food to avoid stomach upset. Your doctor will decide how often you should take this medicine. This may change from time to time depending on how well it is working. You should take this medicine regularly to get the most benefit, even if you feel fine. It is preventing future harm. If you stop taking it, your chest pain may come back.

You can improve the health of your heart by making some lifestyle changes such as quitting smoking, cutting down on alcohol, eating well, taking regular exercise, and managing stress. Some common side effects of this medicine include nausea, vomiting, headache, dizziness, constipation, and weakness. Talk to your doctor if these bother you or do not go away.

Ranolane 500mg Tablet ER may not suitable for some people. Tell your doctor if you are suffering from any liver or kidney problems. Also let your doctor know all other medications you are using as some may affect, or be affected by this medicine. This medicine is not usually recommended during pregnancy or breastfeeding.

Uses of Ranolane Tablet ER

Treatment of Angina (heart-related chest pain)

Benefits of Ranolane Tablet ER

In Treatment of Angina (heart-related chest pain)

Ranolane 500mg Tablet ER reduces the oxygen requirement of the heart and relaxes the heart muscles. It makes sure that your heart is able to perform its functions in the amount of oxygen supply available without causing stress on heart muscles. This makes it less likely that you will suffer chest pain caused by angina. This medicine can help increase your ability to exercise and go about your daily life more easily by reducing the frequency of angina attacks. You should take it regularly and as long as it is prescribed for it to work effectively.

Side effects of Ranolane Tablet ER

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Ranolane

Nausea
Vomiting
Headache
Dizziness
Constipation
Weakness

How to use Ranolane Tablet ER

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ranolane 500mg Tablet ER is to be taken with food.

How Ranolane Tablet ER works

Ranolane 500mg Tablet ER is an anti-anginal medication. It works by decreasing the oxygen requirement of the heart by relaxing heart muscle.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Ranolane 500mg Tablet ER. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Ranolane 500mg Tablet ER may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Ranolane 500mg Tablet ER is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

CONSULT YOUR DOCTOR

It is not known whether Ranolane 500mg Tablet ER alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

CAUTION

Ranolane 500mg Tablet ER should be used with caution in patients with kidney disease. Dose adjustment of Ranolane 500mg Tablet ER may be needed. Please consult your doctor.
Use of Ranolane 500mg Tablet ER is not recommended in patients with severe kidney disease.

Liver

CAUTION

Ranolane 500mg Tablet ER should be used with caution in patients with liver disease. Dose adjustment of Ranolane 500mg Tablet ER may be needed. Please consult your doctor.
Use of Ranolane 500mg Tablet ER is not recommended in patients with moderate to severe liver disease.

What if you forget to take Ranolane Tablet ER?

If you miss a dose of Ranolane 500mg Tablet ER, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Ranolane 500mg Tablet ER

₹12.6/Tablet ER

Rancad Tablet ER

Lupin Ltd

₹20.2/tablet er

60% costlier

Ranozex Tablet ER

Sun Pharmaceutical Industries Ltd

₹19.2/tablet er

52% costlier

Ranx 500 Tablet ER

Torrent Pharmaceuticals Ltd

₹21.07/tablet er

67% costlier

Rancv 500 Tablet ER

MSN Laboratories

₹12.7/tablet er

1% costlier

Ranopill 500 Tablet ER

Intas Pharmaceuticals Ltd

₹15.9/tablet er

26% costlier

View all substitutes

Quick tips

It should be taken with food to avoid stomach upset.
It improves HbA1c and blood sugar levels in diabetes patients.
It may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
Notify your doctor if you are taking any other medications along with Ranolane 500mg Tablet ER
It may produce changes in the ECG (QTc interval prolongation). It is recommended to get an ECG done within 1 to 2 weeks of starting the medication.

Fact Box

Chemical Class

Acetanilide & piperazine derivative

Habit Forming

Therapeutic Class

CARDIAC

Action Class

Late Sodium channel blocker- angina

Patient concerns

What is heart attack? When heart attack coming?

Dr. Nabajit Talukdar

Cardiology

Related to chest pain angina commonly

Chest pain headache vetrigo Angina pain

Dr. Nabajit Talukdar

Cardiology

Get echo n ECG done

FAQs

What are the serious side effects of Ranolane 500mg Tablet ER?

Ranolane 500mg Tablet ER may cause changes in the electrical activity of the heart which is known as QT prolongation. Your doctor may get regular tests done to check the electrical activity of your heart. Tell your doctor right away if you feel faint, lightheaded or if your heart starts beating irregularly or fast, as these may be symptoms of QT prolongation. Ranolane 500mg Tablet ER may also cause kidney failure in patients who already have kidney problems. Therefore, your doctor may need to do tests to check how your kidneys are working.

I started taking Ranolane 500mg Tablet ER about a week ago. Now I have noticed that my urine has become very dark though I am taking plenty of fluids. Is there anything to worry about?

Urine discoloration could be because of Ranolane 500mg Tablet ER. You need not worry if you do not have any other symptoms. However, if it still bothers you, you can talk to your doctor who will advise you further.

In case I accidentally take an excess of Ranolane 500mg Tablet ER, what will happen?

Excess of Ranolane 500mg Tablet ER can cause nausea, vomiting, lightheadedness, double vision, tiredness, severe tremor, confusion, hallucinations, difficulty in speaking and walking and you can even faint. If you have taken an excess of Ranolane 500mg Tablet ER by mistake, call your doctor right away or seek emergency medical care in a nearby hospital.

Is it safe to take Ranolane 500mg Tablet ER if I am already taking metoprolol?

Yes, it is safe to take the Ranolane 500mg Tablet ER and Metoprolol together. Ranolane 500mg Tablet ER has minimal effect on blood pressure in patients with angina.

I am a diabetic and am taking metformin. My doctor has prescribed Ranolane 500mg Tablet ER, is it safe to take both together?

If you are taking metformin along with Ranolane 500mg Tablet ER, you have to be careful since Ranolane 500mg Tablet ER may increase the levels of metformin in the body which can lead to metformin toxicity. Talk to your doctor who will modify the dose of metformin.

I have been taking simvastatin to keep my cholesterol levels in check. Can I take Ranolane 500mg Tablet ER with it?

It is recommended not to take simvastatin and Ranolane 500mg Tablet ER together because it may cause simvastatin toxicity which may lead to symptoms like muscle weakness and soreness, fatigue, decreased urination, etc. Let your doctor know that you are already taking simvastatin. If it is still necessary to take, then take it exactly as advised by the doctor.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Opie LH, Horowitz JD. Nitrates and Newer Antianginals β-Blocking Agents. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. p. 56
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1200.
Ranolazine. Wooburn Green, Buckinghamshire: A. Menarini Farmaceutica Internazionale SRL; 2008 [revised 22 Nov. 2018]. [Accessed 25 Jan. 2019] (online) Available from:
Ranolazine. Foster City, California: Gilead Sciences, Inc.; 2013. [Accessed 20 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:
Ranolazine Sustained Release Tablets [Package Insert]. Ahmedabad, Gujarat: Torrent Pharmaceuticals Ltd.; 2019. [Accessed 25 Jul. 2023] (online) Available from:

Marketer details

Name: Biovia Life Sciences

Address: Jainam Residency, Kailash Colony, Ambernath, Maharashtra 421501

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.