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Refine 0.5mg/10mg Tablet

Prescription Required

Product introduction

Refine 0.5mg/10mg Tablet is a combination of two medicines used in the treatment of depression. It helps by increasing the level of chemical messengers in the brain that relaxes the brain and nerves, thus treating your depression.

Refine 0.5mg/10mg Tablet may be taken with or without food. Take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take it in the dose and duration as advised by your doctor. This medication mustn't be stopped suddenly without talking to your doctor as that may worsen your symptoms.

Some common side effects of Refine 0.5mg/10mg Tablet include dry mouth, constipation, urinary retention, blurred vision, increased heart rate, muscle rigidity, restlessness, and tremor. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, rise slowly if you have been sitting or lying down. It may also cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you.

Before taking it, inform your doctor if you are suffering from thyroid or kidney disease, epilepsy, Parkinson’s disease, glaucoma, or any heart disease. This medicine can also lead to weight gain, eat a healthy balanced diet, avoid snacking with high-calorie food, and exercise regularly.

Uses of Refine Tablet

Benefits of Refine Tablet

In Treatment of Depression

Refine 0.5mg/10mg Tablet is a combination medicine that helps in maintaining the balance of certain chemicals in the brain that affect mood and behavior. This improves your mood, relieves anxiety, tension, helps you sleep better and increases your energy levels. Refine 0.5mg/10mg Tablet prevents extreme changes in mood and helps you feel less agitated. You may experience fewer episodes of depression and low mood.
It can take several weeks for this medicine to work and you may still feel low during this time. It is likely that you will take this medicine for at least six months but possibly much longer. It needs to be taken regularly to work effectively. Do not stop taking it unless your doctor tells you to.

Side effects of Refine Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Refine

  • Constipation
  • Urinary retention
  • Weight gain
  • Sleepiness
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Increased heart rate
  • Increased prolactin level in blood
  • Blurred vision
  • Dryness in mouth
  • Muscle stiffness
  • Tremors
  • Restlessness

How to use Refine Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Refine 0.5mg/10mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Refine Tablet works

Refine 0.5mg/10mg Tablet is a combination of two medicines: Flupenthixol and Melitracen. Flupenthixol is a typical antipsychotic. It works by blocking the action of dopamine, a chemical messenger in the brain that affects thoughts and mood. Melitracen is a tricyclic antidepressant which increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Refine 0.5mg/10mg Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Refine 0.5mg/10mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Refine 0.5mg/10mg Tablet during breastfeeding is not available. Please consult your doctor.
Driving
UNSAFE
Refine 0.5mg/10mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Refine 0.5mg/10mg Tablet in patients with kidney disease. Please consult your doctor.
Liver
CAUTION
Refine 0.5mg/10mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Refine 0.5mg/10mg Tablet may be needed. Please consult your doctor.

What if you forget to take Refine Tablet?

If you miss a dose of Refine 0.5mg/10mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Refine 0.5mg/10mg Tablet
₹7.66/Tablet
₹4.27/tablet
44% cheaper
Franxit 0.5 mg/10 mg Tablet
Intas Pharmaceuticals Ltd
₹8.92/tablet
16% costlier
Nuanixt 0.5 mg/10 mg Tablet
Marc Laboratories Pvt Ltd
₹6.3/tablet
18% cheaper
Ambulax-FM Tablet
Unimarck Pharma India Ltd
₹8.53/tablet
11% costlier
₹7.17/tablet
6% cheaper

Quick tips

  • Refine 0.5mg/10mg Tablet helps treat anxiety and depression.
  • Use caution while driving or doing anything that requires concentration as Refine 0.5mg/10mg Tablet can cause dizziness and sleepiness.
  • Avoid drinking alcohol while taking this medicine because it can make drowsiness worse.
  • It can cause changes in your blood sugar levels. Monitor your blood sugar regularly.
  • Inform your doctor if you have liver disease, thyroid disorder, severe heart disease, or a urinary disorder.
  • Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
  • Let your doctor know you are taking Refine 0.5mg/10mg Tablet before undergoing any surgical procedure.

Fact Box

Habit Forming
No
Therapeutic Class
NEURO CNS

Patient concerns

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My mother having border line cholesterol it's is good to go for any particular brand name refine oil for cooking or what to do
Dr. Nabajit Talukdar
Cardiology
No refine oils mustard oil n desi ghee only
DEPRESSION SUFFERING FROM DEPRESSION
Dr. Jyoti Kapoor Madan
Psychiatry
Depression is a persistent state of sadness that is the result of interaction between one's inner biological and psychological state and gets triggered of with environmental stressors. Reactive depression is in response to a situation like loss, sickness, trauma etc. Endogenous depression occurs without any noticeable environmental stressors. Psychological symptoms include lack of interest, negative thinking, irritability, frustration, feeling demotivated etc. Somatic symptoms like fatigue/ weakness/ lack of sleep/ lack of appetite and other physical symptoms are common. Anxiety is common. In severe cases one may feel helpless and hopeless enough to wish for death or attempt suicide. Treatment includes physical and psychiatric work up following which medicines can be prescribed. In milder cases, psychotherapy or counselling is recommended.
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User feedback


FAQs

What is Refine 0.5mg/10mg Tablet?

Refine 0.5mg/10mg Tablet is a combination of two medicines: Flupenthixol and Melitracen. This medicine is used to treat various forms of mood disorders. It works by balancing the amount of certain natural substances in the brain that are responsible for mood swings.

Can Refine 0.5mg/10mg Tablet be stopped when symptoms are relieved?

No, Refine 0.5mg/10mg Tablet should be continued even if the patient feels well. Instead of stopping the dosage yourself, consult your doctor who might gradually decrease the dosage.

Can the Refine 0.5mg/10mg Tablet cause sleepiness or drowsiness?

Refine 0.5mg/10mg Tablet may make you drowsy or may cause you to suddenly fall asleep during your daily activities. You might not feel drowsy or have any other warning signs before you suddenly fall asleep. Avoid driving a car, operating machinery, working at heights or participating in potentially dangerous activities at the beginning of your treatment until you know how the medication affects you. If you suddenly fall asleep while you are doing something such as watching television, talking, eating or riding a car, or if you become very drowsy, especially during the daytime, call your doctor.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. ACI Limited. Flupenthixol+Melitracen. [Accessed 23 Apr. 2019] (online) Available from:External Link

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