Refra 2.5mg Tablet is used to treat low blood pressure (hypotension). It is used in patients who experience dizziness due to low blood pressure while standing up suddenly from sitting or lying position. This medicine causes tightening of blood vessels and results in elevating your blood pressure.

Refra 2.5mg Tablet can be taken with or without food. This medicine is taken during daytime hours when people stand most often. But, it should not be taken if you are going to lie down for a long time after the dose. You should always take this medicine as advised by the doctor and should never stop it without consulting the doctor. You should monitor your blood pressure regularly while taking this medicine.

Common side effects of this medicine include headache, nausea, rash, urinatry retention, difficulty in urination, and flushing. It may also cause supine hypertension, it is increase in your blood pressure while lying down. Consult your doctor if these side effects bother you.

Before taking this medicine, it is better to let your doctor know if you are suffering from any kidney or liver disease. Also, pregnant women and breastfeeding mothers should consult doctor before taking it. You must inform doctor about all the other medicines that you are taking apart from this medicine. Your doctor may ask for monitoring of kidney and liver function before and during the treatment with this medicine.

Uses of Refra Tablet

Treatment of Low blood pressure

Benefits of Refra Tablet

In Treatment of Low blood pressure

Refra 2.5mg Tablet is used in adults and children to relieve low blood pressure which may occur due to sudden change in posture from lying to sitting or standing up, during an operation or after an injury. This medicine helps to bring back the blood pressure within normal range and therefore prevents any sudden fall or even serious complications that might have otherwise followed due to low blood pressure.

Side effects of Refra Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Refra

Headache
Nausea
Rash
Difficulty in urination
Supine hypertension
Urinary retention
Flushing (sense of warmth in the face, ears, neck and trunk)
Goosebumps

How to use Refra Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Refra 2.5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Refra Tablet works

Refra 2.5mg Tablet is an alpha-adrenergic agonist. It works by activating specific receptors on blood vessels. This causes the blood vessels to tighten, which increases blood pressure.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Refra 2.5mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Refra 2.5mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Refra 2.5mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

CONSULT YOUR DOCTOR

It is not known whether Refra 2.5mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

CONSULT YOUR DOCTOR

There is limited information available on the use of Refra 2.5mg Tablet in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Refra 2.5mg Tablet in patients with liver disease. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Refra 2.5mg Tablet

₹33.33/Tablet

Midgeo Tablet

Centaur Pharmaceuticals Pvt Ltd

₹26.55/tablet

20% cheaper

Actiful Tablet

Tas Med India Pvt Ltd

₹41.14/tablet

23% costlier

Midowin 2.5mg Tablet

Winsun Life Sciences Pvt Ltd

₹47.2/tablet

42% costlier

Midorise 2.5 Tablet

Torrent Pharmaceuticals Ltd

₹56.65/tablet

70% costlier

Midora Tablet

Dr Reddy's Laboratories Ltd

₹83.47/tablet

150% costlier

View all substitutes

Quick tips

Take Refra 2.5mg Tablet at least 4 hours before bedtime to avoid the risk of high blood pressure at night time.
Monitor your blood pressure regularly while taking this medicine.
Inform your doctor if you have a history of the prostate disorder or blood circulation problem.
Inform your doctor immediately if you notice symptoms of chest pain, palpitations, headache, shortness of breath, and blurred vision.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Fact Box

Chemical Class

Ethanolamine derivative

Habit Forming

Therapeutic Class

CARDIAC

Action Class

Alpha-1 adrenoreceptor agonists

Patient concerns

Low blood pressure, low energy

Dr. Aanchal Maheshwari

Ayurveda

Take ashwshila capsule 2 twice daily with milk.

Suffering from low blood pressure

Dr. Khalid Basha

Physician

oh, then wht about ur heamoglobincheck it once please

FAQs

Does Refra 2.5mg Tablet raise blood pressure?

Yes, Refra 2.5mg Tablet may cause high blood pressure when you are lying flat on your back (supine hypertension). This medicine should only be used by people whose low blood pressure affects their day-to-day life and in people who could not be treated successfully with other therapies.

Does Refra 2.5mg Tablet affect heart rate?

Refra 2.5mg Tablet may slow down the heart rate slightly. It should be used cautiously when using it with other medicines (beta blockers, digitalis, etc.) which can further slow down the heart rate. Patients should be monitored if they experience symptoms which are suggestive of slow heart rate.

Why can't I lie down after taking Refra 2.5mg Tablet?

You should not lie down immediately after taking Refra 2.5mg Tablet because of the risk of supine hypertension (high blood pressure which occurs when you are lying flat on your back). Therefore, it is recommended to take the last daily dose at least 4 hours before bedtime. You can reduce the risk of supine hypertension occurring during the night by elevating the head.

Does Refra 2.5mg Tablet work immediately?

Refra 2.5mg Tablet takes about 1 hour to show its effects. However, the action lasts for a short time only, the effect persists for about 2-3 hours.

How do I take Refra 2.5mg Tablet?

Refra 2.5mg Tablet should be taken exactly as directed by your doctor. Refra 2.5mg Tablet is taken orally with or without food. Swallow the tablet as a whole with a glass of water. Usually, it is advised to take the medicine three times a day (morning, midday, and late afternoon [before 6PM]) with a gap of at least 3 hours. Take the last daily dose of Refra 2.5mg Tablet before an evening meal and at least 4 hours before bedtime.

Who should not take Refra 2.5mg Tablet?

Refra 2.5mg Tablet is not advised for patients having allergy to any component of the product, severe heart disease, unusually slow heart rate, high blood pressure, and conditions causing tightening of the arteries. Along with that, treatment with Refra 2.5mg Tablet should be avoided if the patient has enlarged prostate gland, urinary retention (when the bladder can’t empty properly), pheochromocytoma (tumour of the adrenal medulla), acute or severe kidney disease, overactive thyroid, poor vision as a result of diabetes, and narrow-angle glaucoma (elevated pressure in the eye).

Is any monitoring required during Refra 2.5mg Tablet treatment?

You may need to check your blood pressure and get your kidney and liver function tests done before you start taking Refra 2.5mg Tablet. Once you begin the treatment, keep a constant track of your blood pressure and heart rate, especially after lying down.

How will I know that I have developed supine hypertension?

Symptoms of supine hypertension include chest pain, palpitations, shortness of breath, headache, and blurred vision. If you develop these symptoms tell your doctor immediately. The doctor may reduce the dose of Refra 2.5mg Tablet or may discontinue treatment if the symptoms persists.

Can I take metoprolol with Refra 2.5mg Tablet?

Using Refra 2.5mg Tablet and metoprolol together can make your heart rate considerably slow. Hence, you need to be careful while using both together. If you experience slow pulse, dizziness and fainting, inform your doctor as the dose of these medicines may need to be modified.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Westfall TC, WestfallIn DP. Adrenergic Agonists and Antagonists. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 295.
Biaggioni I, Robertson D. Adrenoreceptor Agonists & Sympathomimetic Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 139.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 915-16.
Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:

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