Retefuse 18mg Injection is a medicine that dissolves clots that have formed in blood vessels. It is used to treat a heart attack. It is known as a thrombolytic or “clot-busting” drug. This medicine restores the blood flow to the affected tissue, thereby preventing tissue death.

Retefuse 18mg Injection is an injectable drug, given directly into a vein and it is given by a doctor as soon as possible after the first signs of a heart attack. Your breathing, blood pressure, oxygen levels, and other vital signs will be watched closely. You may be given another medicine to stop blood clotting at the same time or after the treatment.

This medicine may increase your risk of bleeding, so it is better to be careful while shaving, cutting nails, or using sharp objects. Treatment with this drug can also cause nausea, vomiting, decreased blood pressure, and injection site bleeding.

This drug needs to be administered with care by an expert and is not suitable for everyone. There is a long list of situations where you will not be given Retefuse 18mg Injection including if you have had a head injury or surgery on your brain or spinal cord and any current bleeding anywhere in your body. Your healthcare team will need to know a lot about your medical history before giving you this medicine.

Uses of Retefuse Injection

Heart attack

Benefits of Retefuse Injection

In Heart attack

Retefuse 18mg Injection dissolves harmful blood clots that cause heart attack (if they are in the heart). They also dissolve clots that form in other blood vessels. This means that blood can again start to flow freely through your body. This medicine will, therefore, reduce both the damage caused by, and the risk of dying from a heart attack. The sooner the injection is given, the greater are the chances of recovery.

Side effects of Retefuse Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Retefuse

Bleeding disorder
Nausea
Vomiting
Decreased blood pressure
Injection site bleeding

How to use Retefuse Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Retefuse Injection works

Retefuse 18mg Injection is a thrombolytic medication. It works by dissolving the harmful blood clots in the blood vessels. This restores the blood flow to the affected tissue, thereby preventing tissue death and improving outcomes.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Retefuse 18mg Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Retefuse 18mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Retefuse 18mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

NOT RELEVANT

Not relevant, as Retefuse 18mg Injection is intended for use in hospitalised patients.

Kidney

CAUTION

Retefuse 18mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Retefuse 18mg Injection may be needed. Please consult your doctor.
Use of Retefuse 18mg Injection is not recommended in patients with severe kidney disease.

Liver

CAUTION

Retefuse 18mg Injection should be used with caution in patients with liver disease. Dose adjustment of Retefuse 18mg Injection may be needed. Please consult your doctor.
Use of Retefuse 18mg Injection is not recommended in patients with severe kidney disease.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Retefuse 18mg Injection

₹31654/Injection

Retefast Kit

Cipla Ltd

₹23000/injection

30% cheaper

Retefast 18mg Injection

Cipla Ltd

₹33000/injection

1% costlier

Vascium 18mg Injection

Emcure Pharmaceuticals Ltd

₹28333.32/injection

13% cheaper

Retelex 18mg Injection

Abbott

₹32700/injection

same price

Cathlyse 18mg Injection

Biochem Pharmaceutical Industries

₹29750/injection

9% cheaper

Quick tips

It should be given as soon as possible (within 12 hours) after the onset of a heart attack or within 4.5 hours of onset of stroke.
Let your doctor know immediately if you develop any nosebleeds, gum bleeding, black or tarry stools, or bruising.
Do not discontinue the medicines started after this injection as it may increase your chances of having another heart attack or stroke.

Fact Box

Chemical Class

Carboxylic Acids Derivatives

Habit Forming

Therapeutic Class

CARDIAC

Action Class

Plasminogen Activators- Thrombolytics

Patient concerns

Yesterday got sudden chest pain and sweating heart specialist give retefuse injection We are planning for angiography today We are planning for angiography today ??

Dr. Nabajit Talukdar

Cardiology

Yes he needs it

Hrert attack home made best treatment

Dr. Spurthi Magdum

Ayurveda

Well there is no home remedy for heart attackBut Post - Attack to strengthen the heart you can give Arjuna Ksheerapak

What are the health problems that one can get if the one keeps on taking a chronic stress and depression over a prolonged period of time. Seing that im experiencing some symtoms like chronic head ache, nausea, heart pain, gastrointiatinal bleeding, urine in the blood, sleep deprivation, weight loss due to exyreme thinking. Pls advise me in this connection

Dr. Pushkar Mani

Physician

Heart attack, Kidney problems all u can get

What are the trip t normal and high values What should be thresholds for ' no heart'' attack', minor attack and heart attack

Dr. Ila Jain Khandelwal

Pathology

Hello sir. Thank you for consulting with us. Trop T is read as either positive or increased or not positive. Positive Trop T level indicates heart attack and negative Trop t usually indicates no heart attack. Even in minor heart attack, Trop T is positive.

User feedback

What are you using Retefuse Injection for?

Heart attack

100%

How much was the improvement?

Excellent

47%

Average

30%

Poor

23%

What were the side-effects while using Retefuse 18mg Injection?

Decreased blo*

40%

No Side Effec*

20%

Injection sit*

20%

Nausea

20%

*Decreased blood pressure, No Side Effect, Injection site bleeding

How do you take Retefuse Injection?

With food

50%

Empty stomach

33%

With or witho*

17%

*With or without food

Please rate Retefuse 18mg Injection on price

Expensive

53%

Average

33%

Not Expensive

13%

FAQs

Q. How is Retefuse 18mg Injection administered?

Retefuse 18mg Injection should be administered under the supervision of a trained healthcare professional or a doctor only and should not be self-administered. The dose will depend on the condition you are being treated for and will be decided by your doctor. Follow your doctor’s instructions carefully to get maximum benefit from Retefuse 18mg Injection.

Q. Is Retefuse 18mg Injection safe?

Retefuse 18mg Injection is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.

Q. Can the use of Retefuse 18mg Injection increase the risk of bleeding?

Yes, Retefuse 18mg Injection can increase the risk of bleeding. Always be careful while doing activities that may cause an injury or bleeding. Tell your doctor immediately if you notice any abnormal bruising or bleeding.

Q. What medicines should I avoid while taking Retefuse 18mg Injection?

Retefuse 18mg Injection can interact with several medicines. If you are already taking Retefuse 18mg Injection, do not take any other medicine without talking to your doctor.

Q. When will I feel better after taking Retefuse 18mg Injection?

Retefuse 18mg Injection reduces your risk of developing blood clots in the blood vessels of your leg, lungs, heart and brain. You may not feel any difference after taking Retefuse 18mg Injection. This does not mean that the medicine is not working, therefore keep taking this medicine as prescribed.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Fox KA, White HD, Gersh BJ, et al. Antithrombotic Agents: Platelete Inhibitors, Acute Anticoagulants, Fibrinolytics, and Chronic Anticoagulants. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. p. 384.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1208.
Drugs.com. Reteplase. [Accessed 20 Mar. 2019] (online) Available from:

Marketer details

Name: Lupin Ltd

Address: 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India

Country of origin: India

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