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Last updated
16 Dec 2024 | 01:08 AM (IST)

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Rextop 1% Gel

Prescription Required

Product introduction

Rextop 1% Gel is a medicine used to treat a severe form of skin disease called psoriasis when other treatments are not effective. The medicine help kills the cells in the skin which are growing too quickly. It may be also used to treat other conditions, as determined by the doctor.

Rextop 1% Gel is only meant for external use and should be used as advised by your doctor. Your doctor will decide what dose is necessary and how often you need to use it. Do not stop using the medicine without first checking with your doctor. You should use it exactly as your doctor has advised.

The medicine is generally safe and does not usually cause any side effects. However, if you experience any symptoms on using the medicine, let your doctor know. There may be ways of preventing or reducing these effects.

Before using it, tell your doctor if you have liver or kidney problems or are taking any medicines to treat infections. Let your doctor also if you are taking or using any other medications. This medicine is not recommended during pregnancy or while breastfeeding. It can cause harm to your baby.

Uses of Rextop Gel

Benefits of Rextop Gel

In Treatment of Psoriasis

Rextop 1% Gel belongs to a group of medicines called antimetabolites. It may be used to treat severe psoriasis when other treatments have not worked. Psoriasis is a condition where the skin cells in the body grow too quickly. Rextop 1% Gel works by killing these fast-growing cells. It is potent and very toxic medicine and you should discuss the risks and benefits with your doctor. Take it exactly as prescribed and for as long as it is prescribed to get the most benefit. DO NOT take more than you should. It may take several months to become fully effective. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side effects of Rextop Gel

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Rextop

  • No common side effects seen

How to use Rextop Gel

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the gel. Wash your hands after applying, unless hands are the affected area.

How Rextop Gel works

Rextop 1% Gel is an immunosuppressant. In psoriasis, it works by slowing down the rapid growth of skin cells.

Safety advice

Alcohol
No interaction found/established
Pregnancy
UNSAFE
Rextop 1% Gel is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
UNSAFE
Rextop 1% Gel is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
No interaction found/established
Kidney
No interaction found/established
Liver
No interaction found/established

What if you forget to take Rextop Gel?

If you miss a dose of Rextop 1% Gel, use it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Rextop 1% Gel
₹121/Gel
Folitrax LP Gel
Ipca Laboratories Ltd
₹335.4/gel
168% costlier
Dermotrex 1% Gel
East West Pharma
₹440/gel
252% costlier

Fact Box

Chemical Class
Glutamic Acid Derivative
Habit Forming
No
Therapeutic Class
DERMA
Action Class
Antimetabolite- Methotrexate

Interaction with drugs

Taking Rextop with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concurrent use strongly suppresses immunity that may increase the risk of serious infection. Your doctor may closely monitor you for the emergence of infection-related signs and s... More
Concurrent use may decrease the blood levels of Methotrexate. If concurrent use is essential, your doctor may monitor the treatment outcome and may modify the treatment protocol a... More

Patient concerns

arrow
I have some rashes like patches on scalp Fungal infection
Dr. Rajesh Garg
Internal Medicine
Sent Pict. May be psoriasis
Will soriasis come because of tonsils
Dr. Atula Gupta
Dermatology
Yes . Guttate psoriasis can flare up if you have tonsillitis . But the occurrence of. Psoriasis is mostly genetic in nature
arrow

User feedback


FAQs

Is Rextop 1% Gel effective?

Rextop 1% Gel is effective if used in the dose and duration advised by your doctor. Do not stop using it even if you see improvement in your condition. If you stop using Rextop 1% Gel too early, the symptoms may return or worsen.

How to use Rextop 1% Gel?

Before using Rextop 1% Gel, clean and dry the affected area. Gently and thoroughly massage it into the skin. Be careful not to get the medication in your eyes or mouth. If Rextop 1% Gel gets in your eyes accidentally, wash with plenty of water and call your doctor if your eyes are irritated.

What precautions do I need to take while using Rextop 1% Gel?

Be careful not to get Rextop 1% Gel into your eyes or mouth. If you happen to get it in your eyes, rinse off with plenty of water immediately and contact your doctor. You must not use Rextop 1% Gel if you are allergic to it or any of its ingredients. Tell your doctor if you notice any allergic reaction while using it for the first time. Inform your doctor if you are taking any medicines regularly to prevent any allergic reaction with other medicines. Do not cover the area being treated with Rextop 1% Gel with a bandage, as this may increase absorption of this medicine and increase the side effects. Do not use more than what is recommended to relieve your symptoms faster. Using more than what is advised will only increase the side effects. Let your doctor know if you are planning to conceive to avoid any harm to the baby. Pregnant and breastfeeding mothers should use Rextop 1% Gel only if prescribed by the doctor.

What should I do if I forget to use Rextop 1% Gel?

If you forget to use Rextop 1% Gel, do not worry and continue using Rextop 1% Gel as soon as you remember. Do not double the dose to make up for the missed dose. However, if you are not sure and have any other doubts, please consult your doctor.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 944-46.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 887-90.
  3. Central Drugs Standard Control Organisation. Methotrexate. [Accessed 11 Jul. 2023]. (online) Available from:External Link
  4. American Academy of Dermatology Association. Psoriasis Treatment: Methotrexate. [Accessed 11 Jul. 2023]. (online) Available from:External Link
  5. Eskicirak B, Zemheri E, Cerkezoglu A. The treatment of psoriasis vulgaris: 1% topical methotrexate gel. Int J Dermatol. 2006 Aug;45(8):965-9. [Accessed 11 Jul. 2023]. (online) Available from:External Link

Marketer details

Name: Systopic Laboratories Pvt Ltd
Address: 101, Pragati Chambers, Commercial Complex, Ranjit Nagar, New Delhi-110008
Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.

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Same salt composition:Methotrexate (1% w/w)
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