Ryblue Ophthalmic Solution is a blue dye used during cataract surgery to stain the front eye lens capsule. This helps surgeons see the clear lens layer more easily, improving precision. The dye is washed out after use and does not affect deeper eye structures.
Ryblue Ophthalmic Solution is used only during eye surgery by trained eye specialists and is administered by a doctor as a single-use solution during cataract surgery. Since it is applied intraoperatively, there is no requirement for patient self-administration or ongoing adherence post-procedure. It is a one-time application during the procedure, ensuring safety and accuracy without requiring patient adherence afterward.
Ryblue Ophthalmic Solution may cause temporary staining inside the eye, such as on the back part of the lens or the gel-like substance in the eye (vitreous). These effects are usually mild and resolve on their own.
Ryblue Ophthalmic Solution should only be used during eye surgery by trained professionals. It is not suitable if a certain type of lens (dry acrylic lens) is being placed in the eye, as it may get stained. The surgeon will take care to remove any extra dye to avoid unwanted coloring inside the eye.
Ryblue Ophthalmic Solution is a dye used during cataract surgery to help eye surgeons see the front part of the lens (called the anterior capsule). It stains the area and improves visibility and precision during the procedure, making the surgery safer and more effective. It supports better surgical outcomes and clearer vision recovery after cataract surgery.
Side effects of Ryblue Ophthalmic Solution
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Ryblue
Eye discoloration
How to use Ryblue Ophthalmic Solution
This medicine is for external use only. Take it in the dose and duration as advised by your doctor. Check the label for directions before use. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off extra liquid.
How Ryblue Ophthalmic Solution works
Ryblue Ophthalmic Solution works by gently staining the front layer of the eye’s natural lens, which is usually clear and hard to see during cataract surgery. Coloring this layer blue helps the surgeon see the area more clearly and perform delicate steps like cutting and removing the lens with better accuracy. The dye only colors the surface it touches and does not go deeper into the eye.
Safety advice
Alcohol
No interaction found/established
Pregnancy
CONSULT YOUR DOCTOR
The safety of Ryblue Ophthalmic Solution during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding
CAUTION
Ryblue Ophthalmic Solution should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving
NOT RELEVANT
Not relevant, as Ryblue Ophthalmic Solution is intended for use in hospitalized patients.
Kidney
No interaction found/established
Liver
No interaction found/established
What if you forget to take Ryblue Ophthalmic Solution?
If you miss a dose of Ryblue Ophthalmic Solution, please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
Ryblue Ophthalmic Solution is applied only by trained eye surgeons during cataract surgery.
Patients should not attempt to use this product outside of a clinical setting.
As a one-time, intraoperative product, Ryblue Ophthalmic Solution does not require any action from the patient before or after the procedure.
Although Ryblue Ophthalmic Solution itself does not require follow-up use, it is important to follow all post-surgery care instructions provided by your eye doctor to ensure proper healing.
If you have a planned lens implant, make sure to discuss the type with your doctor, as Ryblue Ophthalmic Solution is not suitable for certain dry-state acrylic lenses.
Fact Box
Chemical Class
Azo dyes
Habit Forming
No
Therapeutic Class
OPHTHAL
Action Class
Ocular Dyes
Patient concerns
Eye examination fundus & glaucoma Location of specialist chamber
Etching both eye after using optizee plus eye drop prescribed by doctor and swelling near eye Can I consult physician or the problem is related with eye
When I was sleeping my eyes and whole head was shaking and couldn't sleep for long time.im feeling shivering in the head because of this problem.some of them said it's because of using the mobile for longtime
Heavy muddy and lite itching in both eye last 2 month I using algic plus and refresh tears eye drop but no relief kindly advise new Medicine and management
Dr. Richa Jain
Ophthalmology
U need eye examination to rule out any eye infection or allergy
Yes, when used by trained professionals during surgery, Ryblue Ophthalmic Solution is considered safe. Any excess dye is removed immediately after use.
Will the dye stay in my eye permanently?
No, Ryblue Ophthalmic Solution is temporary. It is washed out during the procedure and does not remain in the eye.
Can it cause side effects?
Some temporary staining inside the eye may occur, but this usually goes away within a week.
Do I need to use this dye after surgery?
No. Ryblue Ophthalmic Solution is a one-time application used only during surgery by your eye doctor.
Who should not use Ryblue Ophthalmic Solution?
It should not be used if a specific type of lens (dry acrylic lens) is going to be implanted, as the dye may stain it.
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
Trypan blue. Scheijdelveweg , VN: D.O.R.C. International b.v.; 2004. [Accessed 10 Apr. 2025] (online) Available from:
Trypan blue. Scheijdelveweg , VN: D.O.R.C. International b.v.; 2023. [Accessed 10 Apr. 2025] (online) Available from:
Marketer details
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