Samezole D 30mg/20mg Capsule SR is a prescription medicine used to treat gastroesophageal reflux disease (Acid reflux) by relieving the symptoms such as heartburn, stomach pain, or irritation. It also neutralizes the acid in the stomach and promotes easy passage of gas to reduce stomach discomfort.

Samezole D 30mg/20mg Capsule SR is taken without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.

Most common side effects are diarrhea, stomach pain, dryness in mouth, headache, and flatulence. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any side effects. It may also cause dizziness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your dizziness. Lifestyle modifications like having cold milk and avoiding hot tea, coffee, spicy food or chocolate can help you to get better results.

Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy or breastfeeding. You should also tell your doctor if you have liver diseases so that your doctor can prescribe a suitable dose for you.

Uses of Samezole D Capsule SR

Treatment of Gastroesophageal reflux disease (Acid reflux)

Benefits of Samezole D Capsule SR

In Treatment of Gastroesophageal reflux disease (Acid reflux)

Gastroesophageal reflux disease (GERD) is a chronic (long-term) condition in which there is an excess production of acid in the stomach. Samezole D 30mg/20mg Capsule SR reduces the amount of acid your stomach makes and relieves the pain associated with heartburn and acid reflux. You should take it exactly as it is prescribed for it to be effective.
Some simple lifestyle changes can help reduce the symptoms of GERD. Think about what foods trigger heartburn and try to avoid them; eat smaller, more frequent meals; try to lose weight if you are overweight and try to find ways to relax. Do not eat within 3-4 hours of going to bed.

Side effects of Samezole D Capsule SR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Samezole D

Diarrhea
Stomach pain
Dryness in mouth
Headache
Flatulence
Fundic gland polyps

How to use Samezole D Capsule SR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Samezole D 30mg/20mg Capsule SR is to be taken empty stomach.

How Samezole D Capsule SR works

Samezole D 30mg/20mg Capsule SR is a combination of two medicines: Domperidone and Omeprazole. Domperidone is a prokinetic which works on the upper digestive tract to increase the movement of the stomach and intestines, allowing the food to move more easily through the stomach. Omeprazole is a proton pump inhibitor (PPI) which works by reducing the amount of acid in the stomach which helps in the relief of acid-related indigestion and heartburn.

Safety advice

Alcohol

CAUTION

Caution is advised when consuming alcohol with Samezole D 30mg/20mg Capsule SR. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Samezole D 30mg/20mg Capsule SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Samezole D 30mg/20mg Capsule SR is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

UNSAFE

Samezole D 30mg/20mg Capsule SR may cause side effects which could affect your ability to drive.
Samezole D 30mg/20mg Capsule SR may cause dizziness and visual disturbances. This may affect your driving ability.

Kidney

CAUTION

Samezole D 30mg/20mg Capsule SR should be used with caution in patients with kidney disease. Dose adjustment of Samezole D 30mg/20mg Capsule SR may be needed. Please consult your doctor.

Liver

CAUTION

Samezole D 30mg/20mg Capsule SR should be used with caution in patients with liver disease. Dose adjustment of Samezole D 30mg/20mg Capsule SR may be needed. Please consult your doctor.
Use of Samezole D 30mg/20mg Capsule SR is not recommended in patients with moderate and severe liver disease.

What if you forget to take Samezole D Capsule SR?

If you miss a dose of Samezole D 30mg/20mg Capsule SR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Samezole D 30mg/20mg Capsule SR

₹4.03/Capsule SR

Ocid-DSR Capsule

Zydus Cadila

₹15.6/capsule sr

287% costlier

Domstal Plus Capsule SR

Torrent Pharmaceuticals Ltd

₹6.3/capsule sr

56% costlier

Omerd 30mg/20mg Capsule SR

Blue Cross Laboratories Ltd

₹4.22/capsule sr

5% costlier

Omross-DSR Capsule

Emami Frank Ross Ltd

₹10.2/capsule sr

153% costlier

DOMSTAL RD 30 MG/20 MG CAPSULE SR

Torrent Pharmaceuticals Ltd

₹6.74/capsule sr

67% costlier

View all substitutes

Quick tips

You have been prescribed Samezole D 30mg/20mg Capsule SR for the treatment of acidity and heartburn.
Take it one hour before the meal, preferably in the morning.
It is a well-tolerated medicine and provides relief for a long time.
Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away.
Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention.
Long-term use can cause weak bones and deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.

Fact Box

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Patient concerns

acid reflux, gastric, sugar stimulate acid reflux.

Dr. Pushkar Mani

Physician

CBC,ESR,LIPID PROFILE,URINE RE/CS, KFT, LFT, VIT D & B estimation,TAKE RABEKIND DSR once a day empty stomach FOR 3 week

Heartburn Mental disorder Depression Frequent persistent heartburn Gastroesophageal reflux disease Irritable bowel syndrome Indigestion Back flow of acid from stomach Difficulty in swallowing Inflammation of esophagus Excess acid secretion by stomach Intestinal or stomach ulcers

Dr. Sunil Sekhri

Diabetology

You need to be examined in clinic to reach a diagnosis and then appropriate medicine can be prescribed

FAQs

Is it safe to use Samezole D 30mg/20mg Capsule SR?

Yes, Samezole D 30mg/20mg Capsule SR is safe for most of the patients. However, in some patients it may cause common side effects like diarrhea, stomach pain, flatulence, dryness in the mouth, dizziness, headache and other uncommon and rare side effects. Inform your doctor if you experience any persistent problem while taking this medicine.

What are the contraindications of Samezole D 30mg/20mg Capsule SR?

The use of Samezole D 30mg/20mg Capsule SR is considered to be harmful in patients with a known hypersensitivity to omeprazole or domperidone or any other inactive ingredients present in the medicine. Cautious use is advised in patients with underlying kidney or liver disease.

What is the best time to take Samezole D 30mg/20mg Capsule SR?

It is best to take the medicine daily before breakfast or on an empty stomach.

Can the use of Samezole D 30mg/20mg Capsule SR cause abnormal heartbeat?

Yes, the use of Samezole D 30mg/20mg Capsule SR can cause an increased risk of irregular heartbeat (serious arrhythmias). These are serious side effects but the chances that it may happen is very low. The risk may be slightly higher in those who are more than 60 years of age.

Does the use of Samezole D 30mg/20mg Capsule SR lead to dry mouth?

Yes, the use of Samezole D 30mg/20mg Capsule SR can cause dry mouth. Dryness of mouth occurs due to Domperidone, which is present in this combination. If you experience dry mouth, drink plenty of water. Take regular sips of water during the day and keep some water on your bedside at night. Cut down the intake of alcohol and avoid smoking. If you have dry mouth, try to use alcohol-free mouthwash as its use increases the risk of tooth decay.

What is the recommended storage condition for Samezole D 30mg/20mg Capsule SR?

Keep this medicine in the container or pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Domperidone maleate. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2003 [revised 14 Nov. 2017]. [Accessed 12 Apr. 2019] (online) Available from:
International Breastfeeding Center. Domperidone. [Accessed 12 Apr. 2019] (online) Available from:
Omeprazole. Wilmington, Delaware: AstraZeneca LP; 1989. [Accessed on 28 Mar. 2019] (online) Available from:
Omeprazole and Domperidone [Patient Information Sheet]. Solan, Himachal Pradesh: Torrent Pharmaceuticals Ltd.; 2020. [Accessed 28th Sept. 2023] (online) Available from:

Marketer details

Name: Sara Remedies

Address: Plot Number, 397, Baltana Main Rd, Industrial Area Phase 2, Panchkula, Haryana 140603

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.