Sentrane 25mg Capsule is a medicine that is similar to vitamin A and is involved in the normal growth of skin cells. It is used in the treatment of psoriasis. It works by stopping the overgrowth and thickening of skin cells.
Sentrane 25mg Capsule is taken with food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine.
The most common side effects are dry lips, dryness in the mouth, skin peeling, joint pain, itching, runny nose, nosebleeds, hair loss, and increased levels of blood fat. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. It may cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can make dizziness worse.
Avoid sun exposure and cover the treated areas with clothing or use a sunscreen before stepping out in the sun. Your doctor may get your regular blood tests done to monitor your liver function and the levels of fats such as cholesterol in your blood. You should tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you. Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy or breastfeeding as Sentrane 25mg Capsule can cause fetal abnormalities.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Sentrane
Lip inflammation
Dryness in mouth
Itching
Skin peeling
Hair loss
Dry skin
Dry eye
Inflammation of the nose
How to use Sentrane Capsule
Take this medicine in the dose and duration as advised by your doctor. Sentrane 25mg Capsule is to be taken with food.
How Sentrane Capsule works
Sentrane 25mg Capsule is a retinoid. It has a structure similar to vitamin A and is involved in the normal growth of skin cells. It works by stopping overgrowth and thickening of skin cells in psoriasis.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Sentrane 25mg Capsule.
Pregnancy
UNSAFE
Sentrane 25mg Capsule is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
CONSULT YOUR DOCTOR
Sentrane 25mg Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Sentrane 25mg Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Sentrane 25mg Capsule should be used with caution in patients with kidney disease. Dose adjustment of Sentrane 25mg Capsule may be needed. Please consult your doctor.
Liver
CAUTION
Sentrane 25mg Capsule should be used with caution in patients with liver disease. Dose adjustment of Sentrane 25mg Capsule may be needed. Please consult your doctor.
What if you forget to take Sentrane Capsule?
If you miss a dose of Sentrane 25mg Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Sentrane 25mg Capsule helps reduce thickening, plaque formation and scaling of the skin in conditions such as psoriasis.
Take it at the same time every day with food or a glass of milk.
Do not take Sentrane 25mg Capsule if you are pregnant, planning pregnancy or breastfeeding as it can cause birth defects in babies. Use effective methods of contraception to prevent pregnancy.
You will need to take pregnancy tests regularly if you are on treatment with and for at least 3 years after you stop taking this medicine.
Avoid exposure to sunlight while using Sentrane 25mg Capsule as it increases the sensitivity of your skin. Use protective measures such as sun-creams and protective clothing.
It may cause dryness of skin, mouth, and lips. Drink plenty of water and use a moisturiser and lip balm, if needed.
It may cause dry eyes and blurring of vision. Avoid wearing contact lenses and be cautious before driving or using machines.
Your doctor may get your regular blood tests done to monitor your liver function and the levels of fats such as cholesterol in your blood.
Sentrane 25mg Capsule helps reduce thickening, plaque formation and scaling of the skin in conditions such as psoriasis.
Take it at the same time every day with food or a glass of milk.
Do not take Sentrane 25mg Capsule if you are pregnant, planning pregnancy or breastfeeding as it can cause birth defects in babies. Use effective methods of contraception to prevent pregnancy.
You will need to take pregnancy tests regularly if you are on treatment with and for at least 3 years after you stop taking this medicine.
Avoid exposure to sunlight while using Sentrane 25mg Capsule as it increases the sensitivity of your skin. Use protective measures such as sun-creams and protective clothing.
It may cause dryness of skin, mouth, and lips. Drink plenty of water and use a moisturiser and lip balm, if needed.
It may cause dry eyes and blurring of vision. Avoid wearing contact lenses and be cautious before driving or using machines.
Your doctor may get your regular blood tests done to monitor your liver function and the levels of fats such as cholesterol in your blood.
Fact Box
Chemical Class
Retinoids
Habit Forming
No
Therapeutic Class
DERMA
Action Class
Retinoids- Second generation
Interaction with drugs
Taking Sentrane with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
No, Sentrane 25mg Capsule is not an immunosuppressant. It belongs to the retinoid class of medicines. It is used to treat severe form of psoriasis.
Can I drink alcohol while taking Sentrane 25mg Capsule?
Do not consume anything that contains alcohol while taking Sentrane 25mg Capsule and for 2 months after treatment. Sentrane 25mg Capsule and alcohol combine to form a substance that may remain in the body for more than 3 years.
How long does Sentrane 25mg Capsule take to work?
Sentrane 25mg Capsule does not work right away. It may take about 2-4 weeks to see an improvement and about 2-3 months before you see the full benefits of this medicine. Therefore, you should continue taking it even if you do not see any improvement initially.
What is the most important information that I should know about Sentrane 25mg Capsule?
Sentrane 25mg Capsule can cause serious birth defects in your unborn child. Therefore, you should not take Sentrane 25mg Capsule if you are pregnant or plan to become pregnant within the next 3 years. Sentrane 25mg Capsule may also cause liver damage. Therefore, contact your doctor immediately if you experience nausea, vomiting, loss of appetite, pain in the upper right part of the stomach, yellowing of the skin or eyes, or dark urine.
Does Sentrane 25mg Capsule affect sperm?
No, Sentrane 25mg Capsule does not affect the sperm. However, it has been seen that small amounts of this medicine may pass into the semen. But, this small amount does not pose a risk to an unborn child.
How should I take Sentrane 25mg Capsule?
It is generally recommended to take Sentrane 25mg Capsule once daily with meals or milk. The dosage varies from person to person and is decided by your doctor. Swallow the medicine whole and do not crush or cut it.
Can I donate blood while on Sentrane 25mg Capsule?
No, you should not donate blood while on Sentrane 25mg Capsule. Moreover, do not donate blood 3 years after stopping the treatment with Sentrane 25mg Capsule. The medicine present in your blood can harm an unborn child if your blood is given to a pregnant mother. However, Sentrane 25mg Capsule does not affect your ability to receive a blood transfusion.
What should I avoid while taking Sentrane 25mg Capsule?
Sentrane 25mg Capsule may affect your night vision. Therefore, you should avoid driving at night. Avoid supplemental foods containing vitamin A while taking this medicine since it may add to the side effects. Also, avoid sunlight and sun lamps as Sentrane 25mg Capsule can make your skin more sensitive to ultraviolet light.
Is Sentrane 25mg Capsule an immunosuppressant?
No, Sentrane 25mg Capsule is not an immunosuppressant. It belongs to the retinoid class of medicines. It is used to treat severe form of psoriasis.
Can I drink alcohol while taking Sentrane 25mg Capsule?
Do not consume anything that contains alcohol while taking Sentrane 25mg Capsule and for 2 months after treatment. Sentrane 25mg Capsule and alcohol combine to form a substance that may remain in the body for more than 3 years.
How long does Sentrane 25mg Capsule take to work?
Sentrane 25mg Capsule does not work right away. It may take about 2-4 weeks to see an improvement and about 2-3 months before you see the full benefits of this medicine. Therefore, you should continue taking it even if you do not see any improvement initially.
What is the most important information that I should know about Sentrane 25mg Capsule?
Sentrane 25mg Capsule can cause serious birth defects in your unborn child. Therefore, you should not take Sentrane 25mg Capsule if you are pregnant or plan to become pregnant within the next 3 years. Sentrane 25mg Capsule may also cause liver damage. Therefore, contact your doctor immediately if you experience nausea, vomiting, loss of appetite, pain in the upper right part of the stomach, yellowing of the skin or eyes, or dark urine.
How should I take Sentrane 25mg Capsule?
It is generally recommended to take Sentrane 25mg Capsule once daily with meals or milk. The dosage varies from person to person and is decided by your doctor. Swallow the medicine whole and do not crush or cut it.
Can I donate blood while on Sentrane 25mg Capsule?
No, you should not donate blood while on Sentrane 25mg Capsule. Moreover, do not donate blood 3 years after stopping the treatment with Sentrane 25mg Capsule. The medicine present in your blood can harm an unborn child if your blood is given to a pregnant mother. However, Sentrane 25mg Capsule does not affect your ability to receive a blood transfusion.
What should I avoid while taking Sentrane 25mg Capsule?
Sentrane 25mg Capsule may affect your night vision. Therefore, you should avoid driving at night. Avoid supplemental foods containing vitamin A while taking this medicine since it may add to the side effects. Also, avoid sunlight and sun lamps as Sentrane 25mg Capsule can make your skin more sensitive to ultraviolet light.
Does Sentrane 25mg Capsule affect sperm?
No, Sentrane 25mg Capsule does not affect the sperm. However, it has been seen that small amounts of this medicine may pass into the semen. But, this small amount does not pose a risk to an unborn child.
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References
Burkhart C, Morrell D, Goldsmith L. Dermatological Pharmacology. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1812.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 15-17.
Acitretin. Huddersfield, UK: Genus Pharmaceuticals; 2015 [revised 12 Dec. 2016]. [Accessed 28 Jan. 2019] (online) Available from:
Acitretin. Palo Alto, CA: Connetics Corporation; Mar. 2004. [Accessed 03 Apr. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 29 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 03 Apr. 2019] (online) Available from:
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