Sibolone Tablet
Prescription Required
Product introduction
Sibolone Tablet is a female sex hormone (estrogen). This is a type of hormone replacement therapy (HRT) that is used to treat symptoms associated with menopause (hot flushes, vaginal dryness, and itching), estrogen deficiency, and thinning of bones (osteoporosis).
Sibolone Tablet can be taken with or without food, but better to take it at a fixed time each day for better efficacy. It should be swallowed whole with water. The dose and duration will be decided by your doctor so that you get the right amount to control your symptoms. If you have missed a dose, take it as soon as you remember it. Do not skip any dose and finish the full course of treatment. The treatment should not be stopped abruptly without consulting your doctor as this may affect the potency of this medicine.
The most common side effects of this medicine are lower abdominal pain, abnormal hair growth, endometrial hyperplasia, vaginal discharge, breast tenderness, genital itching, vaginal bleeding, pelvic pain, cervical thickening, and weight gain. Some of the warning signs and symptoms that need immediate medical attention are breast lumps, unusual vaginal bleeding, dizziness and faintness, severe headaches, chest pain, shortness of breath, pains in your legs. If you experience any such effects, consult your doctor.
Before taking this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same disease or other diseases. Before you initiate with this HRT, you must consult the doctor if you have a history of unexplained vaginal bleeding or if you have ever had a blood clot in your legs or your lungs. If you are pregnant or breastfeeding, you should tell your doctor before taking this medicine. Your doctor may suggest you some diagnostic or laboratory tests to know the effects and side effects of this medicine on your body.
Uses of Sibolone Tablet
Side effects of Sibolone Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Sibolone
- Postmenopausal hemorrhage
- Cervical dysplasia
- Abnormal cervical smear
- Vaginal yeast infection
- Weight gain
- Vaginal bleeding
- Endometrial hyperplasia
- Vaginal discharge
- Pelvic pain
- Breast tenderness
- Genital itching
- Lower abdominal pain
- Abnormal hair growth
How to use Sibolone Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sibolone Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Sibolone Tablet works
Sibolone Tablet is a hormonal medication. It has effects similar to estrogen, progesterone and androgen. It substitutes for the loss of estrogen production in postmenopausal women and treats menopausal symptoms such as hot flashes, night sweats and vaginal problems. It also prevents bone loss following menopause.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Sibolone Tablet.
Pregnancy
UNSAFE
Sibolone Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Sibolone Tablet during breastfeeding is not available. Please consult your doctor.
Driving
SAFE
Sibolone Tablet does not usually affect your ability to drive.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Sibolone Tablet in patients with kidney disease. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Sibolone Tablet in patients with liver disease. Please consult your doctor.
What if you forget to take Sibolone Tablet?
If you miss a dose of Sibolone Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
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Quick tips
- Sibolone Tablet is used as a part of hormone replacement therapy to relieve symptoms of menopause such as hot flushes, vaginal dryness, depression, and night sweats.
- It may also be used for preventing osteoporosis in women who have attained menopause and are at high risk of fractures.
- Take it at the same time everyday to help you remember to take it.
- It may cause bleeding or spotting in between menstrual periods. Let your doctor know if this occurs frequently.
- Stop taking Sibolone Tablet and inform your doctor immediately if you get severe headaches, stabbing pains or swelling in one leg, and pain on breathing. These could be symptoms of a blood clot in a vein.
- Ensure that you regularly check your breasts for any changes and undergo regular breast screening and cervical smear tests while on treatment with this medicine.
- Do not use Sibolone Tablet if you have a history of blood clots and liver disease.
- Sibolone Tablet is used as a part of hormone replacement therapy to relieve symptoms of menopause such as hot flushes, vaginal dryness, depression, and night sweats.
- It may also be used for preventing osteoporosis in women who have attained menopause and are at high risk of fractures.
- Take it at the same time everyday to help you remember to take it.
- It may cause bleeding or spotting in between menstrual periods. Let your doctor know if this occurs frequently.
- Stop taking Sibolone Tablet and inform your doctor immediately if you get severe headaches, stabbing pains or swelling in one leg, and pain on breathing. These could be symptoms of a blood clot in a vein.
- Ensure that you regularly check your breasts for any changes and undergo regular breast screening and cervical smear tests while on treatment with this medicine.
- Do not use Sibolone Tablet if you have a history of blood clots and liver disease.
Fact Box
Chemical Class
Oxosteroids
Habit Forming
No
Therapeutic Class
GYNAECOLOGICAL
Action Class
Estrogens
Interaction with drugs
Taking Sibolone with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
If used together, Darunavir may affect blood levels of Tibolone.
It is recommended to use barrier methods (like condoms), IUDs, or a depot for contraception. Your doctor may monit
Mycophenolate mofetil may reduce the efficacy of Tibolone.
Effective contraception must be used before, during, and for at least 6 weeks after stopping Mycophenolate mofetil. It i
Tibolone may reduce the efficacy of Fulvestrant.
Do not consume Fulvestrant with Tibolone if you have or had breast cancer. If essential, consult your doctor.
Tibolone may reduce the efficacy of Raloxifene.
Do not consume Raloxifene with Tibolone. If concurrent use is essential, please consult your doctor.
Concurrent use may increase the risk of formation of blood clots.
If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observatio
Patient concerns
User feedback
Patients taking Sibolone Tablet
Once A Day
92%
Alternate Day
5%
Twice A Day
3%
What are you using Sibolone Tablet for?
Hormone repla*
50%
Post menopaus*
25%
Others
25%
*Hormone replacement therapy, Post menopausal osteoporosis
How much was the improvement?
Average
40%
Excellent
33%
Poor
27%
What were the side-effects while using Sibolone Tablet?
No Side Effec*
60%
Weight gain
20%
Abnormal hair*
20%
*No Side Effect, Abnormal hair growth
How do you take Sibolone Tablet?
With food
100%
Please rate Sibolone Tablet on price
Not Expensive
67%
Expensive
33%
FAQs
Does Sibolone Tablet contain progesterone?
It is a synthetic medicine which is used to fulfill the functions of the normal sex hormones like estrogen and progesterone in the body of women. On taking Sibolone Tablet it is broken down in our body and functions like estrogen, progesterone and a part to testosterone (male sex hormone). It is prescribed to compensate for the loss of estrogen production in postmenopausal women and decrease the menopausal symptoms.
Is Sibolone Tablet a combined HRT?
Yes, Sibolone Tablet is a type of medicine used in hormone replacement therapy (HRT) which is given to post-menopausal women. It is given to prevent the adverse effects on various organs and systems due to decrease in the levels of hormones like estrogen and progesterone. It shows positive effect on different tissues in the body, such as brain, vagina, and bones.
Can Sibolone Tablet be taken during pregnancy?
No, Sibolone Tablet is not to be taken in pregnancy or if you are planning to get pregnant. In case you become pregnant during treatment with this medication you should contact your doctor and the medicine should be withdrawn immediately.
Does Sibolone Tablet help in elevating mood?
Yes, this medicine has shown positive results when given to postmenapausal women as a substitute for the hormonal deprivation. Patients have experienced reduction in the menopausal complaints like persistent fatigue, blunted motivation, and loss of sexual desire. However, consult the doctor regarding any query for your mood problems before you start taking this medication.
Can Sibolone Tablet help in osteoporosis?
Yes, Sibolone Tablet can help in osteoporosis. After menopause some women become prone to develop fragile bones called osteoporosis which can lead to an increased risk of fractures. Sibolone Tablet acts as a replacement for the female sex hormones when given in the post-menopausal phase. These hormones help in increasing bone density. Therefore, taking Sibolone Tablet can prevent bone loss and osteoporosis. Do consult your doctor before starting this medication as you might need other supplemental medications to treat osteoporosis.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Tibolone. London, UK: ADVANZ Pharma; 2016 [revised 26 Apr. 2016]. [Accessed 23 Jan. 2019] (online) Available from:
- Tibolone. Hoddesdon, Hertfordshire: Merck Sharp & Dohme Limited; 2009 [revised 22 Mar. 2016] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 04 Apr. 2019] (online) Available from:
- Tibolone [EMC SmPC]. London, UK: Organon Pharma (UK) Limited; 2023. [Accessed 08 May 2024] (online) Available from:
Marketer details
Name: Serum Institute Of India Ltd
Address: 212/2, Hadapsar, Off Soli Poonawalla Road, Pune 411028 India
Country of origin: India
Expires on or after: March, 2026
A licensed vendor partner from your nearest location will deliver Sibolone Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Expires on or after: March, 2026
A licensed vendor partner from your nearest location will deliver Sibolone Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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