Signi Clav 500mg/125mg Tablet is an antibiotic that helps your body fight infections caused by bacteria. It is used to treat infections of the lungs (e.g., pneumonia), ear, nasal sinus, urinary tract, skin, and soft tissue. It will not work for viral infections such as the common cold.

Signi Clav 500mg/125mg Tablet is best taken with a meal to reduce the chance of a stomach upset. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time daily will help you remember to take it. The dose will depend on what you are being treated for, but you should always complete an entire course of this antibiotic as your doctor prescribes. Please do not stop taking it until you have finished, even when you feel better. If you stop taking it early, some bacteria may survive, and the infection may return or worsen.

The most common side effects of Signi Clav 500mg/125mg Tablet include nausea, diarrhea, vomiting, fungal infections of the mouth, skin fold or vagina, skin rashes, and vaginitis. These are usually mild, but let your doctor know if they bother you or will not go away.

Before taking it, let your doctor know if you are allergic to any antibiotics or have kidney or liver problems. You should also inform your healthcare team about all other medicines you are taking as they may affect or be affected by Signi Clav 500mg/125mg Tablet. This medicine is generally considered safe to use during pregnancy and breastfeeding if prescribed by a doctor.

Uses of Signi Clav Tablet

Treatment of Bacterial infections

Benefits of Signi Clav Tablet

In Treatment of Bacterial infections

Signi Clav 500mg/125mg Tablet contains two medicines, Amoxycillin and Clavulanic Acid, that work together to kill the bacteria that cause infections. Amoxycillin works by stopping the growth of bacteria. Clavulanic Acid reduces resistance and enhances the activity of Amoxycillin against bacteria.
Signi Clav 500mg/125mg Tablet can treat many bacterial infections such as ear, sinus, throat, lung, urinary tract, skin, teeth, joints, and bones. It usually makes you feel better within a few days, but you should continue taking it as prescribed even when you feel better to ensure all bacteria are killed and do not become resistant.

Side effects of Signi Clav Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Signi Clav

Vaginal inflammation
Mucocutaneous candidiasis
Vomiting
Nausea
Diarrhea
Skin rash
Red spots or bumps
Fungal infection

How to use Signi Clav Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Signi Clav 500mg/125mg Tablet is to be taken with food.

How Signi Clav Tablet works

Signi Clav 500mg/125mg Tablet is a combination of two medicines: Amoxycillin and Clavulanic Acid. Amoxycillin is an antibiotic. It works by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria. Clavulanic Acid is a beta-lactamase inhibitor which reduces resistance and enhances the activity of Amoxycillin against bacteria.

Safety advice

Alcohol

SAFE

Consuming alcohol with Signi Clav 500mg/125mg Tablet does not cause any harmful side effects.

Pregnancy

SAFE IF PRESCRIBED

Signi Clav 500mg/125mg Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding

SAFE IF PRESCRIBED

Signi Clav 500mg/125mg Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.

Driving

UNSAFE

Signi Clav 500mg/125mg Tablet may cause side effects which could affect your ability to drive.
Signi Clav 500mg/125mg Tablet may cause side effects such as allergic reactions, dizziness or fits that may make you unfit to drive.

Kidney

CAUTION

Signi Clav 500mg/125mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Signi Clav 500mg/125mg Tablet may be needed. Please consult your doctor.
Use of this medicine is not recommended in patients with severe kidney disease.

Liver

CAUTION

Signi Clav 500mg/125mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Signi Clav 500mg/125mg Tablet may be needed. Please consult your doctor.
Regular monitoring of liver function tests is recommended while you are taking this medicine

What if you forget to take Signi Clav Tablet?

If you miss a dose of Signi Clav 500mg/125mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and return to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Signi Clav 500mg/125mg Tablet

₹16.4/Tablet

Amoxyclav 625 Tablet

Abbott

₹15.2/tablet

7% cheaper

Omniclav 625 Tablet

Cipla Ltd

₹15/tablet

9% cheaper

Novaclav 625 Tablet

Cipla Ltd

₹15/tablet

9% cheaper

Augmentin 625 Duo Tablet

Glaxo SmithKline Pharmaceuticals Ltd

₹20.1/tablet

23% costlier

Clavam 625 Tablet

Alkem Laboratories Ltd

₹19.4/tablet

18% costlier

View all substitutes

Quick tips

Diarrhea may occur as a side effect. Taking probiotics along with Signi Clav 500mg/125mg Tablet may help. Talk to your doctor if you notice bloody stools or develop abdominal cramps.
Do not take antacids 2 hours before or after taking Signi Clav 500mg/125mg Tablet.
Stop taking Signi Clav 500mg/125mg Tablet and inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking it.
Do not use leftover medicine for treating any infection in the future. Always consult your doctor before taking any antibiotic.
Stick to simple meals, avoid rich or spicy food and drink plenty of water while taking Signi Clav 500mg/125mg Tablet.

Fact Box

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Patient concerns

Scar on face due to bacterial infections

Dr. Atul Jain

Dermatology

Pic is not clear, plz visit for proper opinion

I have a history of recurring yeast and bacterial vaginosis infections.

Dr. Sonu Balhara Ahlawat

Obstetrics and Gynaecology

Tab metrogyl 500 mg twice a day x 5 days and tab fluconazole 150 mg three doses alternate days

User feedback

What are you using Signi Clav Tablet for?

Bacterial inf*

100%

*Bacterial infections

FAQs

What is Signi Clav 500mg/125mg Tablet?

Signi Clav 500mg/125mg Tablet is a combination of two medicines: Amoxycillin and Clavulanic acid. It is used to treat bacterial infections like, tonsillitis, sinusitis, otitis media, respiratory tract infections, urinary tract infections, boils, abscesses, cellulitis, wound infection, bone infection, and oral cavity infections. The medicine works by killing the harmful bacteria that cause infections.

Is it safe to use Signi Clav 500mg/125mg Tablet?

Signi Clav 500mg/125mg Tablet is safe to use when taken as advised by the doctor. However, in some patients, it may cause common side effects like diarrhea, nausea, vomiting, rash, allergic reaction and other uncommon or rare side effects. If you experience any persistent problem during the course of your treatment, inform your doctor as soon as possible.

Are there any specific cautions associated with the use of Signi Clav 500mg/125mg Tablet?

The use of Signi Clav 500mg/125mg Tablet is considered to be harmful for patients with known allergy to penicillins or any other ingredient of the medicine. It should not be used in patients with a history of liver disease. Therefore, inform your doctor if you are allergic to any medicines.

Can the use of Signi Clav 500mg/125mg Tablet cause contraceptive failure?

Yes, the use of Signi Clav 500mg/125mg Tablet can lower the efficacy of birth control pills. Consult your doctor and seek advice regarding the use of other methods of contraception (e.g., condom, diaphragm, spermicide) while you are taking Signi Clav 500mg/125mg Tablet.

Can I take a higher than the recommended dose of Signi Clav 500mg/125mg Tablet?

No, taking a higher than the recommended dose of Signi Clav 500mg/125mg Tablet can increase the risks of side effects. Signi Clav 500mg/125mg Tablet takes time to show its full effect and treat your infection. If you are experiencing increased severity of your symptoms, please consult your doctor for re-evaluation.

What are the instructions for the storage and disposal of Signi Clav 500mg/125mg Tablet?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose off the unused medicine. Make sure it is not consumed by pets, children and other people.

Can I stop taking Signi Clav 500mg/125mg Tablet when my symptoms are relieved?

No, do not stop taking Signi Clav 500mg/125mg Tablet before completing the full course of the treatment, even if you feel better. Your symptoms may improve before the infection is completely cured. Hence, continue taking the medicine for the due course as the medicine may still be showing beneficial effects.

Can Signi Clav 500mg/125mg Tablet cause an allergic reaction?

Yes, Signi Clav 500mg/125mg Tablet can cause an allergic reaction. It is considered to be harmful for patients with known allergy to penicillins. Get emergency medical help if you have any signs of allergic reaction like hives, difficulty breathing, or swelling of your face, lips, tongue or throat.

Can the use of Signi Clav 500mg/125mg Tablet cause diarrhea?

Yes, the use of Signi Clav 500mg/125mg Tablet can cause diarrhea. It is an antibiotic which kills the harmful bacteria. In addition to that, the medicine may affect the helpful bacteria in your stomach or intestine as well and cause diarrhea. In case you experience diarrhea, drink plenty of water or other fluids. Talk to your doctor if diarrhea persists and you notice any signs of dehydration, like less frequency of urination with dark colored and strong-smelling urine. Do not take any other medicine without consulting a doctor.

Can I take Signi Clav 500mg/125mg Tablet to treat cold and flu?

No, Signi Clav 500mg/125mg Tablet does not treat a viral infection like the common cold or flu. Consult your doctor and avoid self-medication.

Will Signi Clav 500mg/125mg Tablet cause drowsiness?

No Signi Clav 500mg/125mg Tablet does not cause drowsiness. If you experience any such effects, consult your doctor.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Amoxicillin/clavulanate potassium. Research Triangle Park, North Carolina: GlaxoSmithKline. [Accessed 25 Jan. 2019] (online) Available from:
Amoxicillin and clavulanic acid. Mayenne, France: Glaxo Wellcome Production; 2017. [Accessed 01 Feb. 2019] (online) Available from:

Marketer details

Name: Signity Pharmaceuticals Pvt Ltd

Address: PLOT NO. 10, FLAT NO. 1, GROUND FLOOR DNYANYOG APARTMENT, DEO NAGAR, KHAMLA ROAD NAGPUR Nagpur MH 440015 IN , - , .

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.