Simstat 20mg Tablet belongs to a group of medicines called statins. It is used to lower cholesterol and reduce the risk of heart disease. Cholesterol is a fatty substance that builds up in your blood vessels and causes narrowing, which may lead to a heart attack or stroke.

Simstat 20mg Tablet is usually taken in the evening, either with or without food. However, taking it with food may reduce the chances of nausea. Take it regularly for maximum benefit. Most people with high cholesterol do not feel ill, but stopping your medicine may increase your cholesterol levels, making your condition worse and increasing your risk of heart disease and stroke.

It is important to have your cholesterol levels checked regularly. This medicine is only one part of the treatment program which should also include a healthy diet, regular exercise, smoking cessation, moderation of alcohol intake, and weight reduction. You can eat normally while taking this medicine, but try to avoid foods that are high in fat.

Common side effects of Simstat 20mg Tablet include upper respiratory infections, headache, abdominal pain, constipation, and nausea. These are usually mild and temporary. Consult your doctor if they persist. Inform your doctor or if you notice any yellowing of your eyes or get repeated or unexplained muscle pains.

Simstat 20mg Tablet should not be used in individuals with severe liver disease. Also, pregnant and breastfeeding women should not take this medicine as it may harm the baby. Diabetic patients should monitor their blood sugar levels while taking this medicine, as it may lead to an increase in blood sugar levels.

Uses of Simstat Tablet

High cholesterol
High triglycerides
Prevention of heart attack and stroke

Benefits of Simstat Tablet

In Prevention of heart attack and stroke

High levels of cholesterol can cause your blood vessels to narrow (atherosclerosis) and put you at risk of having a stroke or heart disease. Lowering the amount of this fat reduces the chances of this happening and helps you remain healthier for longer. Keep taking this medicine even if you feel well.

Side effects of Simstat Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Simstat

Constipation
Headache
Upper respiratory tract infection
Abdominal pain
Nausea

How to use Simstat Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Simstat 20mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Simstat Tablet works

Simstat 20mg Tablet is a lipid-lowering medication (statin). It works by blocking an enzyme (HMG-CoA-reductase) that is required in the body to make cholesterol. It thus lowers "bad" cholesterol (LDL) and triglycerides, raising the level of "good" cholesterol (HDL).

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Simstat 20mg Tablet.

Pregnancy

UNSAFE

Simstat 20mg Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Breast feeding

UNSAFE

Simstat 20mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Simstat 20mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Simstat 20mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Simstat 20mg Tablet may be needed. Please consult your doctor.

Liver

CAUTION

Simstat 20mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Simstat 20mg Tablet may be needed. Please consult your doctor.
Use of Simstat 20mg Tablet is not recommended in patients with severe liver disease and active liver disease.

What if you forget to take Simstat Tablet?

If you miss a dose of Simstat 20mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Simstat 20mg Tablet

₹14.0/Tablet

Simvotin 20 Tablet

Sun Pharmaceutical Industries Ltd

₹31.1/tablet

122% costlier

Simlup 20mg Tablet

Lupin Ltd

₹5.25/tablet

62% cheaper

Zosta 20 Tablet

USV Ltd

₹15.46/tablet

10% costlier

Simvas 20mg Tablet

Micro Labs Ltd

₹6.54/tablet

53% cheaper

Simcard 20mg Tablet

Cipla Ltd

₹17.33/tablet

24% costlier

View all substitutes

Quick tips

It should be taken in the evening after dinner and before sleeping.
It should be taken in addition to regular exercise and low-fat diet to lower levels of fat in the blood.
Inform your doctor if you experience fatigue, muscle weakness or muscle pain.
Your doctor may check your liver function before starting the treatment and regularly thereafter. Inform your doctor if you notice signs of liver problems such as stomach pains, unusually dark urine or yellowing of skin or eyes.
Inform your doctor if you have kidney disease, liver disease or diabetes before starting treatment with this medicine. If you are diabetic, monitor your blood sugar level regularly as Simstat 20mg Tablet may cause an increase in your blood sugar level.
Do not take Simstat 20mg Tablet if you are pregnant, planning a pregnancy or breastfeeding.

Fact Box

Chemical Class

Delta valerolactones derivative

Habit Forming

Therapeutic Class

CARDIAC

Action Class

HMG-CoA Reductase Inhibitors (Statins)

Interaction with drugs

Taking Simstat with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Clarithromycin (Oral Route) Life-threatening

Concurrent use may cause muscle damage. Clarithromycin may raise blood levels of Simvastatin. Do not consume Simvastatin with Clarithromycin. If Clarithromycin is essential, your d... More

Ciclosporin (Injection Route) Life-threatening

Concurrent use may cause damage to muscles and kidneys. Ciclosporin may raise blood levels of Simvastatin. Do not consume Simvastatin with Ciclosporin. If concurrent use is essenti... More

Atazanavir (Oral Route) Life-threatening

Concurrent use may cause muscle damage. Atazanavir may raise blood levels of Simvastatin. Do not consume Simvastatin with Atazanavir.

Ciclosporin (Oral Route) Life-threatening

Concurrent use may cause damage to muscles and kidneys. Ciclosporin may raise blood levels of Simvastatin. Do not consume Simvastatin with Ciclosporin. If concurrent use is essenti... More

Clarithromycin (Injection Route) Life-threatening

Concurrent use may cause muscle damage. Clarithromycin may raise blood levels of Simvastatin. Do not consume Simvastatin with Clarithromycin. If Clarithromycin is essential, your d... More

View all drug interactions

Patient concerns

high triglycerides, High TSH Low Vitamin D

Dr. Saurabh Arora

Cardiology

Do u smoke or drinkFamily history of heart disease

Fatty liver with poor LFT and backpain Also high triglycerides and high bad cholesterol

Dr. Aanchal Maheshwari

Ayurveda

Capsule cytozen twice, aarogyavardhini vati tablet 2 tablet twice, lipistat capsule 2 capsule twice, punarnava kwath 20 ml twice before meal for 2-3 months

What are the trip t normal and high values What should be thresholds for ' no heart'' attack', minor attack and heart attack

Dr. Ila Jain Khandelwal

Pathology

Hello sir. Thank you for consulting with us. Trop T is read as either positive or increased or not positive. Positive Trop T level indicates heart attack and negative Trop t usually indicates no heart attack. Even in minor heart attack, Trop T is positive.

FAQs

What should I know about high cholesterol?

Cholesterol is a type of fat present in your blood. Total cholesterol is determined by the total amount of LDL and HDL cholesterol in the body. LDL cholesterol is called “bad” cholesterol. Bad cholesterol can build up in the wall of your blood vessels and slow or obstruct blood flow to your heart, brain, and other organs. This can cause heart disease and stroke. HDL cholesterol is called “good” cholesterol as it prevents the bad cholesterol from building up in the blood vessels. High levels of triglycerides are also harmful for you.

What is Simstat 20mg Tablet used for? How does it work?

Simstat 20mg Tablet belongs to a class of medicines called statins that lower the cholesterol in the blood. It is used along with a healthy diet and exercise to reduce bad cholesterol and increase the amount of good cholesterol in the blood. It works by slowing the production of cholesterol in the liver in order to decrease the amount of cholesterol that accumulates on the walls of arteries. Improving the levels of cholesterol in the blood helps to reduce the risk of heart attack or stroke.

When should I take Simstat 20mg Tablet?

Simstat 20mg Tablet is generally taken once a day preferably in the evening after dinner. Try taking this medicine at the same time every day to help remember when to take it.

For how long should I take Simstat 20mg Tablet?

You may need to take Simstat 20mg Tablet for life or for as long as directed by your doctor. The cholesterol levels will be maintained only till you are taking Simstat 20mg Tablet. Stopping Simstat 20mg Tablet without starting a different treatment may increase your cholesterol levels again. This medicine has only a few side effects and is usually considered safe if taken as directed by the doctor.

What foods should be avoided when taking Simstat 20mg Tablet?

Simstat 20mg Tablet is used to decrease your blood cholesterol levels. Therefore, to seek the best results of this medicine, you should avoid foods which are high in calories like fried food and junk food. It is recommended to eat a low-fat and low-cholesterol diet. Be sure to follow all the exercise and dietary recommendations made by your doctor or dietician.

Does Simstat 20mg Tablet make you tired?

Yes, Simstat 20mg Tablet can make you feel tired. This is because they reduce the energy supply to the muscles in the body. However, the exact reason behind the phenomenon is unknown and needs more research. Tiredness usually occurs after exertion. Generalized fatigue is more often seen in people with heart disease or those suffering from liver illness. Simstat 20mg Tablet also causes muscle damage which further worsens the tiredness and so you must consult your doctor if you feel tired while taking Simstat 20mg Tablet.

Can I take alcohol with Simstat 20mg Tablet?

No, it is not advised to take alcohol with Simstat 20mg Tablet. This is because the risk of developing liver problems increases if you drink alcohol while taking this medicine. Moreover, there is a significant increase in the triglyceride levels if Simstat 20mg Tablet is taken along with alcohol. This can further lead to liver damage and also worsen some of the side effects such as muscle pain, muscle weakness and tenderness. People with liver problems are therefore advised not to take Simstat 20mg Tablet without consulting their doctor. They must also refrain from consuming alcohol while taking this medicine to get maximum benefit.

Is Simstat 20mg Tablet safe to take?

Yes, Simstat 20mg Tablet is safe to use if used as prescribed by the doctor and if the doctor's instructions are followed. The side effects of this medicine are few and do not occur in everyone.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Bersot TP. Drug Therapy for Hypercholesterolemia and Dyslipidemia. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 893-902.
Gotto AM Jr, Opie LH. Lipid-Modifying Antiatherosclerotic Drugs. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 418-19.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1266-67.
Simvastatin [FDA Label]. Cramlington, Northumberland, UK: Merck Sharp & Dohme Ltd.; 2012. [Accessed 20 Apr. 2020]. (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Simvastatin. [Updated 2018 Oct 31]. [Accessed 19 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:
Simvastatin [Drug Label]. Whitehouse Station, NJ: Merck & Co. Inc.; 2012. [Accessed 25 Jul. 2024] (online) Available from:

Marketer details

Name: Emcure Pharmaceuticals Ltd

Address: 255/2, Hinjawadi, Pune - 411057, India

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.