Sisliptin M 500mg/20mg Tablet ER is a combination of two medicines that control high blood sugar levels in people with type 2 diabetes mellitus. This helps prevent serious complications of diabetes such as kidney damage and blindness and may also reduce your chances of having a heart attack or stroke.

Sisliptin M 500mg/20mg Tablet ER can be prescribed alone or together with other diabetes medications. All diabetes medicines work best when used along with a healthy diet and regular exercise. The dose you are given will depend on your condition, blood sugar levels, and what other medicines you are taking. Taking it with meals helps to reduce the chances of developing an upset stomach.

You should take it regularly, at the same time each day, to get the most benefit and you should not stop unless your doctor recommends it. It is controlling your blood sugar levels and helping to prevent serious complications in the future. It is important to stay on the diet and exercise program recommended by your doctor while taking this medicine. Your lifestyle plays a big part in controlling diabetes.

The most common side effects of taking this medicine include diarrhea, nausea, vomiting, upset stomach, and headache. Low blood sugar level (hypoglycemia) is a possible side effect if you are also taking other diabetes medicines like insulin or sulfonylurea, so you need to know how to recognize and deal with it.

This medicine is not suitable for everyone. Before taking it, you should let your doctor know if you have ever had kidney, liver, or heart disease, problems with your pancreas, or if you drink a lot of alcohol. Pregnant or breastfeeding women should also consult their doctor before taking this medicine. Some other medicines can affect this one so tell your doctor about all the medicines you are taking to make sure you are safe. You should try to avoid drinking alcohol as it lowers blood glucose. Your doctor will check your kidney function and blood sugar levels before and during treatment.

Uses of Sisliptin M Tablet ER

Treatment of Type 2 diabetes mellitus

Benefits of Sisliptin M Tablet ER

In Treatment of Type 2 diabetes mellitus

Sisliptin M 500mg/20mg Tablet ER is a combination of two medicines that work together in different ways to lower your blood glucose levels. Lowering blood glucose levels is an essential part of managing diabetes. If you can control your blood glucose level, your risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs is also lowered. Additionally, proper control of diabetes can also reduce the risk of heart disease and stroke. Taking this medicine regularly along with proper diet and exercise will help you live a normal, healthy life. You should keep using this medicine for as long as it is prescribed because it is protecting your future health.

Side effects of Sisliptin M Tablet ER

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Sisliptin M

Nausea
Vomiting
Headache
Hypoglycemia (low blood glucose level)
Diarrhea

How to use Sisliptin M Tablet ER

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sisliptin M 500mg/20mg Tablet ER is to be taken with food.

How Sisliptin M Tablet ER works

Sisliptin M 500mg/20mg Tablet ER is a combination of two antidiabetic medicines:.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Sisliptin M 500mg/20mg Tablet ER.

Pregnancy

CONSULT YOUR DOCTOR

Sisliptin M 500mg/20mg Tablet ER may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Sisliptin M 500mg/20mg Tablet ER is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

CONSULT YOUR DOCTOR

It is not known whether Sisliptin M 500mg/20mg Tablet ER alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

CAUTION

Sisliptin M 500mg/20mg Tablet ER should be used with caution in patients with kidney disease. Dose adjustment of Sisliptin M 500mg/20mg Tablet ER may be needed. Please consult your doctor.
Use of Sisliptin M 500mg/20mg Tablet ER is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.

Liver

UNSAFE

Sisliptin M 500mg/20mg Tablet ER is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

What if you forget to take Sisliptin M Tablet ER?

If you miss a dose of Sisliptin M 500mg/20mg Tablet ER, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Sisliptin M 500mg/20mg Tablet ER

₹11.4/Tablet ER

Glytrin-Met Tablet ER

Medley Pharmaceuticals

₹16/tablet er

40% costlier

Morglin-M Tablet ER

Morningg Life Pharmaceuticals Pvt Ltd

₹11.9/tablet er

4% costlier

Tenligon-M 500 Tablet ER

Gonan Pharma

₹13.8/tablet er

21% costlier

Tagon-M Tablet ER

Intas Pharmaceuticals Ltd

₹19.25/tablet er

69% costlier

Tenzulix M 500 Tablet ER

Torrent Pharmaceuticals Ltd

₹14/tablet er

23% costlier

View all substitutes

Quick tips

You have been prescribed this combination medicine as it can control blood sugar better than metformin alone.
Take it in addition to regular exercise and a healthy diet to lower levels of blood sugar.
Take it with food to lower your chance of having an upset stomach.
Chances of weight gain and low blood sugar are lesser as compared to other diabetes medicines.
Monitor your blood sugar level regularly while you are taking this medicine.
Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic.
Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting, and stomach pain as Sisliptin M 500mg/20mg Tablet ER may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.

Fact Box

Habit Forming

Therapeutic Class

ANTI DIABETIC

Patient concerns

Diabetes mellitus type 2 ,thirst

Dr. Sanjay Bhatt

Physician

A person can control his or her sugar levels by doing regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOUR DOCTOR AND FOLLOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you should not treat it as disease but a start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications like kidney or heart problems .online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET

Diabetes mellitus type 2 required only ayurvedic medicine

Dr. Sanjay Bhatt

Physician

Go for allopathic medicine

Any latest discoveris for type 1 mellitus Diabetes?

Dr. Sanjay Bhatt

Physician

Diabetes Ireland is delighted to hear of the Harvard success and congratulate Professor Melton and colleagues on figuring out the complex series of steps necessary to turn stem cells into beta cells. Hopefully, they can negotiate the regulations for mass production so that an abundant supply of beta cells is available an new and innovative methods will be developed to cure/treat Type 1 diabetes. Type I diabetes is an autoimmune condition whereby the body kills off its own beta (insulin producing) cells resulting in the need for daily insulin administration through the skin. Replacing beta cells in the first step towards a cure, but the replaced beta cells need to be protected from the body?s autoimmune response. This means protecting them in a coating or taking drugs to prevent the response (possible worse side effects than diabetes).

How to manage diabetes mellitus

Dr. Sanjay Bhatt

Physician

A person can control his or her sugar levels by regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOU DOCTOR AND LOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you souls not treat it as disease but start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications.online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET

FAQs

Is it safe to use Sisliptin M 500mg/20mg Tablet ER?

Yes, it is safe to use Sisliptin M 500mg/20mg Tablet ER if you take it for the prescribed duration and according to the dosage advised by the doctor. However, despite taking the prescribed dosage you might experience common side effects like nausea, diarrhea, vomiting, stomach upset, headache, nasal congestion, sore throat, respiratory tract infection and hypoglycemia (low blood sugar level). Hypoglycemia is relatively common in patients who are taking Sisliptin M 500mg/20mg Tablet ER in combination with insulin or Sulfonylurea. Inform your doctor if you experience any persistent problem while taking this medicine.

Can the use of Sisliptin M 500mg/20mg Tablet ER lead to hypoglycemia?

The use of Sisliptin M 500mg/20mg Tablet ER does not usually cause hypoglycemia (low blood sugar level) on its own. But, it could occur if there is insufficient supplementation of calories while taking this medicine. Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate, and feeling anxious or shaky. The symptoms are more likely to be noticed if you miss or delay your food, drink alcohol, over-exercise or take any other antidiabetic medicine along with it. Hence, regular monitoring of blood sugar level is important. It is recommended to always carry glucose tablets, honey or fruit juice with you.

Can the use of Sisliptin M 500mg/20mg Tablet ER cause nausea and vomiting?

Yes, the use of Sisliptin M 500mg/20mg Tablet ER can cause nausea and vomiting. In case of vomiting, drink plenty of water or other fluids by taking small frequent sips. Talk to your doctor if vomiting persists and you notice signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicine without consulting a doctor.

Are there any specific contraindications associated with the use of Sisliptin M 500mg/20mg Tablet ER?

The use of Sisliptin M 500mg/20mg Tablet ER should be avoided in patients with known allergy to any of the components or excipients of this medicine. The use of this medicine is also considered to be harmful for patients with severe kidney impairment, liver impairment, congestive heart failure, lactic acidosis or diabetic ketoacidosis.

Can the use of Sisliptin M 500mg/20mg Tablet ER cause lactic acidosis?

Yes, the use of Sisliptin M 500mg/20mg Tablet ER can lead to lactic acidosis which is also known as MALA (Metformin-associated lactic acidosis). It is caused by increased levels of lactic acid in the blood. It is a very rare side effect associated with the use of metformin and therefore it is avoided in patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Sisliptin M 500mg/20mg Tablet ER and immediately consult your doctor.

Can the use of Sisliptin M 500mg/20mg Tablet ER lead to Vitamin B12 deficiency?

Yes, the use of Sisliptin M 500mg/20mg Tablet ER can cause Vitamin B12 deficiency on long-term use. It interferes with the absorption of Vitamin B12 in the stomach. Deficiency of B12 may cause anemia and nerve problems. These may further cause a tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). Consult your doctor if you experience these symptoms. Your doctor may advise monitoring of B12 levels and prescribe a vitamin B12 supplement if required.

What is the storage condition for the Sisliptin M 500mg/20mg Tablet ER?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Show less

Related lab tests

Glucose - Fasting Blood

Glucose - Postprandial Blood

Glycosylated Hemoglobin

Top Diabetologists

Dr. Beena Bansal

MBBS, MD, DM

4.4 ★

Dr. Harmandeep K. Gill

4.5 ★

4.8 ★

MBBS, Diploma, Diploma, Diploma, DNB, Diploma, Fellowship, Fellowship, Fellowship

5 ★

Dr. Jasjeet Singh Wasir

MBBS, MD

4.7 ★

Want to share the information?

Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Metformin hydrochloride. Princeton, New Jersey: Bristol-Myers Squibb Company. [Accessed 08 Apr. 2019] (online) Available from:
Kishimoto M. Teneligliptin: A DPP-4 inhibitor for the treatment of type 2 diabetes. Diabetes Metab Syndr Obes. 2013;6:187-95. [Accessed 08 Apr. 2019] (online) Available from:
Metformin hydrochloride oral solution. Gloversville, New York: Ranbaxy Pharmaceuticals Inc.; 2003. [Accessed 08 Apr. 2019] (online) Available from:
Teneligliptin and Metformin hydrochloride [Product Monograph] Mumbai, Maharashtra: Panacea Biotec Limited; 2019. [Accessed 20 Oct. 2021] (online) Available from:
Teneligliptin and Metformin hydrochloride [Product information] Pune, India: Centaur Pharma Ltd.; 2018. [Accessed 20 Oct. 2021] (online) Available from:
Teneligliptin and Metformin hydrochloride [Packaging information] Pune, India: Centaur Pharma Ltd. [Accessed 20 Oct. 2021] (online) Available from:
Teneligliptin and Metformin Hydrochloride ER [Patient Information Sheet]. Ahmedabad, Gujarat: TORRENT PHARMACEUTICALS LTD.; 2016. [Accessed 28th Sept. 2023] (online) Available from:

Marketer details

Name: Millennial Pharmaceuticals Private Limited

Address: Plot No 559,Netaji Nagar Nallagandla,Serilingampally Hyderabad Rangareddi Tg 500019 In

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.