Sistal AP Tablet is a pain relieving medicine. It is used to treat pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It may also be used to relieve muscle pain, back pain, toothache, or pain in the ear and throat.

Sistal AP Tablet should be taken with food. This will prevent you from getting an upset stomach. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. You should take it as advised by your doctor. Do not take more or use it for longer duration than recommended by the doctor.

The most common side effects of this medicine include nausea, vomiting, heartburn, stomach pain, and indigestion. If any of these side effects do not resolve with time or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing them.

Before taking it, you should let your doctor know if you have a history of ulcer or bleeding in your stomach, high blood pressure, or have any problems with your heart, kidneys, or liver. Let your doctor also know about all the other medicines you are taking to make sure it is safe for you.

Pregnant or breastfeeding women should consult their doctor before starting treatment. You should also avoid drinking alcohol while you are taking this medicine, as alcohol can cause excessive drowsiness.

Uses of Sistal AP Tablet

Pain relief

Benefits of Sistal AP Tablet

In Pain relief

Sistal AP Tablet relieves pain, reduce swelling and ease inflammation in conditions like rheumatoid arthritis, osteoarthritis and ankylosing spondolytis. It also helps to manage short term symptoms such as muscle and back pain, toothache, or pain in the ear and throat if taken when the first sign of pain occurs. It works by reducing substances in the body that causes pain and swelling. Sistal AP Tablet also reduces fever associated with various painful conditions within 1-2 hour of taking a dose.

Side effects of Sistal AP Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Sistal AP

Nausea
Vomiting
Heartburn
Stomach pain
Indigestion
Loss of appetite
Diarrhea

How to use Sistal AP Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sistal AP Tablet is to be taken with food.

How Sistal AP Tablet works

Sistal AP Tablet is a combination of three medicines: Aceclofenac, Paracetamol and Trypsin Chymotrypsin, which relieves pain. Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) and Paracetamol is an antipyretic (fever reducer). They work by blocking the release of certain chemical messengers in the brain that cause pain and fever. Trypsin Chymotrypsin is a combination of enzymes which break down proteins into smaller fragments, thereby making them available for absorption into the blood. Once absorbed, they increase blood supply in the affected area and reduce swelling.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Sistal AP Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Sistal AP Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Sistal AP Tablet during breastfeeding is not available. Please consult your doctor.

Driving

UNSAFE

Sistal AP Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Sistal AP Tablet should be used with caution in patients with kidney disease. Dose adjustment of Sistal AP Tablet may be needed. Please consult your doctor.
Use of Sistal AP Tablet is not recommended in patients with severe kidney disease.

Liver

CAUTION

Sistal AP Tablet should be used with caution in patients with liver disease. Dose adjustment of Sistal AP Tablet may be needed. Please consult your doctor.
However, the use of Sistal AP Tablet is not recommended in patients with severe liver disease and active liver disease.

What if you forget to take Sistal AP Tablet?

If you miss a dose of Sistal AP Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Sistal AP Tablet

₹10.7/Tablet

Chymoral-AP Tablet

Torrent Pharmaceuticals Ltd

₹17.2/tablet

61% costlier

Chymonet AP Tablet

Leeford Healthcare Ltd

₹8.13/tablet

24% cheaper

Chymocad Tablet

Cadila Pharmaceuticals Ltd

₹13.5/tablet

26% costlier

Chymolift Plus 100mg/325mg Tablet

Werke Healthcare

₹14.5/tablet

36% costlier

Chymoking AP 100mg/325mg Tablet

Nusmith Pharma Pvt. Ltd

₹14.4/tablet

35% costlier

View all substitutes

Quick tips

You have been prescribed this combination medicine for relieving pain and inflammation.
Take it with food to avoid getting an upset stomach.
It may cause dizziness and sleepiness. Don't drive or do anything that requires mental focus until you know how it affects you.
Avoid consuming alcohol when taking Sistal AP Tablet as it may cause excessive drowsiness and increase the risk of liver damage.
Do not take it with any other medicine containing acetaminophen (drugs for pain/fever or cough-and-cold) without asking your doctor first.

Fact Box

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Patient concerns

Swelling and pain in my right knee since last few days. Applied volini but no relief. No injuries happened.

Dr. Akshat Goel

Orthopaedics

Get a Digital x-ray done of both knees AP-view in standing position and share itApply Dynapar QPS spray and take Tab Sistal-plus thrice daily for 2 days

I have riding bike on for 35 km. After that my left wrist has pain. I have taken pain killer & apply move on wrist. But no more relief. Pl suggest what can I do?

Dr. Akshat Goel

Orthopaedics

Take Tab Sistal-plus thrice daily and apply Dynapar QPS spray for 5 days

User feedback

Patients taking Sistal AP Tablet

Twice A Day

100%

What are you using Sistal AP Tablet for?

Pain relief

50%

Dental pain

50%

FAQs

What is Sistal AP Tablet?

Sistal AP Tablet is a combination of four medicines: Aceclofenac, Paracetamol, Trypsin and Chymotrypsin. This medicine helps in decreasing pain and swelling. It lowers the levels of chemical substances in the body that causes pain and swelling.

Can I get addicted to Sistal AP Tablet?

No, there is no report of any patient getting addicted to Sistal AP Tablet.

Can I stop taking Sistal AP Tablet when my pain is relieved?

Sistal AP Tablet is usually used for short term and can be discontinued when your pain is relieved. However, Sistal AP Tablet should be continued if your doctor has advised you to do so.

Can the use of Sistal AP Tablet cause dizziness?

Yes, the use of Sistal AP Tablet can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for some time and resume once you feel better.

Can the use of Sistal AP Tablet cause damage to kidneys?

Yes, long-term use of Sistal AP Tablet can cause damage to the kidneys. Normal kidneys produce a chemical called prostaglandins that protects them from damage. Use of painkillers lowers the levels of prostaglandins in the body leading to kidney damage due to long-term use. Use of painkillers is not recommended to patients with underlying kidney disease.

Can the use of Sistal AP Tablet cause damage to liver?

Sistal AP Tablet contains Paracetamol. This medicine is known to cause harm to the liver especially in the doses above the recommended level. Also, avoid drinking alcohol while taking this medicine, as it may further increase your risk of liver damage. Use of this medicine should preferably be avoided in patients with underlying liver disease. Contact your doctor immediately if you notice any early signs and symptoms of liver damage. These symptoms may include fever, rash, loss of appetite, nausea, vomiting, fatigue, stomach pain, dark urine, yellow skin or eyes and abnormal liver enzymes.

How long will Sistal AP Tablet take to act?

It may take about an hour to see the initial benefit of pain relief after taking Sistal AP Tablet.

What if I forget to take Sistal AP Tablet?

If you forget to take the scheduled dose of Sistal AP Tablet and it is almost time for your next dose, skip the dose you missed and take your next dose at the scheduled time. Otherwise, take it as soon as you remember, and then go back to taking your medicine as you would normally. Do not take a double dose to make up for the dose you missed because this may increase the risk of unwanted side effect. If you are not sure what to do, consult your doctor about how to manage a situation like this.

Will a higher than the recommended dose of Sistal AP Tablet be more effective?

No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having some serious side effects and toxicity. If you experience increased severity of your symptoms, that are not relieved by the recommended doses, please consult your doctor for re-evaluation.

Are there any specific contraindications associated with the use of Sistal AP Tablet?

The use of Sistal AP Tablet is considered to be harmful for patients with known allergy to any of the component or excipients of this medicine. The use of this medicine should preferably be avoided in patients with a history of stomach ulcers or in patients with active, recurrent stomach ulcer / bleeding. It should also be avoided in patients with history of heart failure, high blood pressure, and liver or kidney disease.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Shah D, Mital K. The Role of Trypsin: Chymotrypsin in Tissue Repair. Adv Ther. 2018;35(1):31-42. [Accessed 22 Apr. 2019] (online) Available from:
Trypsin-Chymotrypsin with Paracetamol and Aceclofenac Tablets [Patient Information Leaflet]. Ahmedabad, Gujarat: Torrent Pharmaceuticals; 2020. [Accessed 16 Sep. 2024] (online) Available from:

Marketer details

Name: BestoChem Formulations India Ltd

Address: G-54 3rd FLOOR LAXMI NAGAR VIKAS MARG DELHI -110092

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.