Sivel 400mg Tablet
Prescription Required
Product introduction
Sivel 400mg Tablet is used to treat increased phosphate levels in the blood. It is used in patients who are on dialysis due to severe kidney disease. It inhibits the absorption of phosphate from the intestine and lowers the phosphate levels in the blood.
Sivel 400mg Tablet should be taken with food. Take it in the dose and duration as advised by your doctor. Take it regularly and at a fixed time each day to get the maximum benefit of the medicine.
Sivel 400mg Tablet may cause side effects such as nausea, vomiting, abdominal pain, constipation, and diarrhea. You may also develop low levels of calcium, folic acid, and vitamins A, D, E, and K in your blood. Take necessary supplements as advised by your doctor.
Uses of Sivel Tablet
Side effects of Sivel Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Sivel
- Abdominal pain
- Diarrhea
- Flatulence
- Vomiting
- Constipation
- Nausea
How to use Sivel Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sivel 400mg Tablet is to be taken with food.
How Sivel Tablet works
Sivel 400mg Tablet inhibits the absorption of phosphate from the intestine and lower the phosphate levels in the blood.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Sivel 400mg Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Sivel 400mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Sivel 400mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Sivel 400mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
Sivel 400mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Sivel 400mg Tablet is recommended.
However, regular monitoring of calcium levels is advisable in these patients.
However, regular monitoring of calcium levels is advisable in these patients.
Liver
SAFE IF PRESCRIBED
Sivel 400mg Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Sivel 400mg Tablet may not be needed in these patients. Please consult your doctor.
What if you forget to take Sivel Tablet?
If you miss a dose of Sivel 400mg Tablet, skip it and continue with your normal schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Sivel 400mg Tablet
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Quick tips
- Sivel 400mg Tablet is used to control blood phosphate level in patients that are on dialysis treatment.
- You must take it with food and stick to the diet prescribed by your doctor.
- You may develop low levels of calcium, folic acid, and vitamins A,D,E, and K in your blood. Your doctor may prescribe supplements, if necessary.
- Avoid taking any other medicine 1 hour before or 3 hours after taking Sivel 400mg Tablet.
- Inform your doctor if you have nausea, vomiting, constipation, pain in the abdomen, or if you have undergone any major stomach surgery.
- Sivel 400mg Tablet is used to control blood phosphate level in patients that are on dialysis treatment.
- You must take it with food and stick to the diet prescribed by your doctor.
- You may develop low levels of calcium, folic acid, and vitamins A,D,E, and K in your blood. Your doctor may prescribe supplements, if necessary.
- Avoid taking any other medicine 1 hour before or 3 hours after taking Sivel 400mg Tablet.
- Inform your doctor if you have nausea, vomiting, constipation, pain in the abdomen, or if you have undergone any major stomach surgery.
Fact Box
Chemical Class
Epoxide
Habit Forming
No
Therapeutic Class
BLOOD RELATED
Action Class
Phosphorous binder
Interaction with drugs
Taking Sivel with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Sevelamer may reduce blood levels of Sparfloxacin.
To take Sparfloxacin, ensure a gap of at least 1 hour before and 3 hours after taking Sevelamer.
Sevelamer may reduce blood levels of Norfloxacin.
To take Norfloxacin, ensure a gap of at least 1 hour before and 3 hours after taking Sevelamer.
Sevelamer may reduce blood levels of Levofloxacin.
To take Levofloxacin, ensure a gap of at least 1 hour before and 3 hours after taking Sevelamer.
Sevelamer may reduce blood levels of Ciprofloxacin.
To take Ciprofloxacin, ensure a gap of at least 1 hour before and 6 hours after taking Sevelamer.
Sevelamer may reduce blood levels of Ofloxacin.
To take Ofloxacin, ensure a gap of at least 1 hour before and 3 hours after taking Sevelamer.
Patient concerns
User feedback
Patients taking Sivel 400mg Tablet
Thrice A Day
44%
Twice A Day
33%
Once A Day
22%
FAQs
Is Sivel 400mg Tablet taken with food?
Yes, Sivel 400mg Tablet can be taken with food. It is recommended to take 1-2 tablets (based on individual needs) thrice daily. It is important to take it with meals because Sivel 400mg Tablet works by binding to phosphate from food. Take it exactly as advised by your doctor.
Can Sivel 400mg Tablet be crushed?
No, you should not crush, chew, or break Sivel 400mg Tablet into pieces. You should swallow it as a whole with water.
Why is it important for me to take Sivel 400mg Tablet?
It is important to take Sivel 400mg Tablet as patients undergoing dialysis cannot control the phosphate levels in their blood, especially after a meal. When the level of phosphate exceeds above the range in the blood, it may cause problems such as itchy skin, red eyes, high blood pressure, bone pain, and also increase the risk of fractures. These increased serum phosphate levels are reduced by Sivel 400mg Tablet, as it binds phosphate from food in the digestive tract.
Does Sivel 400mg Tablet cause constipation?
A common side effect of Sivel 400mg Tablet is constipation, though it does not occur in everyone. The other common side effects of the stomach and intestine include diarrhea, indigestion, flatulence, and pain in the abdomen. Immediately consult your doctor if these side effects become severe and disturb you.
Who should not take Sivel 400mg Tablet?
Patients who are allergic to Sivel 400mg Tablet and who have low levels of phosphate in blood should avoid taking Sivel 400mg Tablet. Additionally, patients having intestinal obstruction should also avoid using Sivel 400mg Tablet.
Can I take ciprofloxacin while I am taking Sivel 400mg Tablet?
Ciprofloxacin may interfere with the working of Sivel 400mg Tablet and therefore it should not be taken at the same time as Sivel 400mg Tablet. However, if taken together then a gap of at least 2 hours before or 6 hours after taking Sivel 400mg Tablet should be maintained.
How long do I need to take Sivel 400mg Tablet?
Continue taking Sivel 400mg Tablet as long as recommended by your doctor. Sivel 400mg Tablet lowers your dietary phosphate levels but does not cure your disease. Hence, you may have to take it lifelong, as stopping Sivel 400mg Tablet may increase your phosphate levels.
Do I need to have any tests while taking Sivel 400mg Tablet?
Yes, serum phosphate levels should be monitored regularly while you are taking Sivel 400mg Tablet. Also, the use of Sivel 400mg Tablet may decrease the levels of vitamin D, A, E, K, and folic acid and hence the levels need to be monitored during the treatment.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1259.
- Medscape. Sevelamer. [Accessed 6 Apr. 2019] (online) Available from:
- Sevelamer hydrochloride. Guildford, Surrey: SANOFI; 2000 [revised 20 Dec. 2018]. [Accessed 30 Jan. 2019] (online) Available from:
- Sevelamer. Cambridge, USA: Genzyme Corporation; 1998. [Accessed 6 Apr. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 6 Apr. 2019] (online) Available from:
- Sevelamer Carbonate [Product Information]. Ahmedabad, Gujarat: La Renon. [Accessed 06 Aug. 2023]. (online) Available from:
- National Center for Biotechnology Information. PubChem Compound Summary for , Sevelamer. [Accessed 06 Aug. 2023]. (online) Available from:
Marketer details
Name: Sanzyme Ltd
Address: PO Bag No. : 1014, Banjara Hills, Hyderabad – 500034
Country of origin: India
Expires on or after: March, 2026
A licensed vendor partner from your nearest location will deliver Sivel 400mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Expires on or after: March, 2026
A licensed vendor partner from your nearest location will deliver Sivel 400mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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