Symet 5mg/500mg Tablet belongs to a category of medicines known as anti-diabetic drugs. It is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.

Symet 5mg/500mg Tablet should be taken with food. Take it regularly at the same time each day to get the most benefit. Your doctor will decide what dose is best for you and this may change from time to time according to how it is working according to your blood sugar levels.

Keep taking this medicine, even if you feel well or your blood sugar levels are controlled. If you stop it without consulting your doctor, your blood sugar levels could rise and put you at risk of kidney damage, blindness, nerve problems and loss of limbs. Remember that it is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Your lifestyle plays a big part in controlling diabetes.

The most common side effect of Symet 5mg/500mg Tablet is low blood glucose levels (hypoglycemia). Make sure you recognize the signs of having low blood glucose levels, such as sweating, dizziness, headache, and shaking and know how to deal with it. To prevent this, it's important to have regular meals and always carry a fast-acting source of glucose such as sugary food or fruit juice with you. Drinking alcohol can also increase your risk of low blood sugar levels and should be avoided. Other side effects that may be seen on taking this medicine include nausea, diarrhea, stomach pain, headache, and upper respiratory tract infection. Some people may find that they put on weight with this medicine.

You should not take it if you have type 1 diabetes mellitus, if you have diabetic ketoacidosis (high levels of acid in your blood), or if you have severe kidney or liver disease. Before taking this medicine, tell your doctor if you have ever had heart disease. It may not be suitable. Pregnant or breastfeeding women should also consult their doctor before taking it. Your blood sugar levels should be checked regularly and your doctor may also advise blood tests to monitor your blood cell counts and liver function.

Uses of Symet Tablet

Type 2 diabetes mellitus

Side effects of Symet Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Symet

Dizziness
Diarrhea
Nausea
Flatulence
Headache
Upper respiratory tract infection

How to use Symet Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Symet 5mg/500mg Tablet is to be taken with food.

How Symet Tablet works

Glibenclamide is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Symet 5mg/500mg Tablet.

Pregnancy

SAFE IF PRESCRIBED

Symet 5mg/500mg Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding

CAUTION

Symet 5mg/500mg Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.

Driving

CONSULT YOUR DOCTOR

It is not known whether Symet 5mg/500mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

UNSAFE

Symet 5mg/500mg Tablet is probably unsafe to use in patients with kidney disease and should be avoided. Please consult your doctor.

Liver

CAUTION

Symet 5mg/500mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Symet 5mg/500mg Tablet may be needed. Please consult your doctor.

What if you forget to take Symet Tablet?

If you miss a dose of Symet 5mg/500mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Symet 5mg/500mg Tablet

₹1.75/Tablet

Glucored Forte Tablet

Sun Pharmaceutical Industries Ltd

₹7/tablet

300% costlier

Diabetrol Tablet

Abbott

₹6.2/tablet

254% costlier

Duotrol Tablet

USV Ltd

₹3.8/tablet

117% costlier

Dibeta GB 5 mg/500 mg Tablet

Torrent Pharmaceuticals Ltd

₹3.3/tablet

89% costlier

Glinil-M Tablet

Cipla Ltd

₹2.8/tablet

60% costlier

View all substitutes

Quick tips

You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Symet 5mg/500mg Tablet.
Take it with food to lower your chance of having an upset stomach.
It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic.
Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Symet 5mg/500mg Tablet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).
Take it with food to lower your chance of having an upset stomach.
You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Symet 5mg/500mg Tablet.
It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic.
Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Symet 5mg/500mg Tablet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

Fact Box

Habit Forming

Therapeutic Class

ANTI DIABETIC

Patient concerns

Diabetes mellitus type 2 ,thirst

Dr. Sanjay Bhatt

Physician

A person can control his or her sugar levels by doing regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOUR DOCTOR AND FOLLOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you should not treat it as disease but a start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications like kidney or heart problems .online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET

Diabetes mellitus type 2 required only ayurvedic medicine

Dr. Sanjay Bhatt

Physician

Go for allopathic medicine

Any latest discoveris for type 1 mellitus Diabetes?

Dr. Sanjay Bhatt

Physician

Diabetes Ireland is delighted to hear of the Harvard success and congratulate Professor Melton and colleagues on figuring out the complex series of steps necessary to turn stem cells into beta cells. Hopefully, they can negotiate the regulations for mass production so that an abundant supply of beta cells is available an new and innovative methods will be developed to cure/treat Type 1 diabetes. Type I diabetes is an autoimmune condition whereby the body kills off its own beta (insulin producing) cells resulting in the need for daily insulin administration through the skin. Replacing beta cells in the first step towards a cure, but the replaced beta cells need to be protected from the body?s autoimmune response. This means protecting them in a coating or taking drugs to prevent the response (possible worse side effects than diabetes).

How to manage diabetes mellitus

Dr. Sanjay Bhatt

Physician

A person can control his or her sugar levels by regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOU DOCTOR AND LOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you souls not treat it as disease but start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications.online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET

FAQs

What is Symet 5mg/500mg Tablet?

Symet 5mg/500mg Tablet is a combination of two medicines: Glibenclamide and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves the blood glucose levels in adults when taken along with proper diet and regular exercise. Glibenclamide lowers the blood glucose levels by increasing the release of insulin from the pancreas. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. This combination is not indicated for the treatment of Type 1 DM.

What is type 2 diabetes?

Type 2 diabetes is the most common form of diabetes. It is a condition in which the body is unable to make enough insulin, and the insulin produced by the body does not work well. When this happens, the glucose level in the blood rises and leads to serious medical problems. Symptoms of high blood sugar include frequent urination, increased thirst and increased hunger. Diabetes, if not treated properly, can cause long-term complications like neuropathy (nerve damage), nephropathy (kidney damage), eye damage (retinopathy), foot problems and also a higher risk of developing heart diseases.

What are the possible side effects of Symet 5mg/500mg Tablet?

The use of Symet 5mg/500mg Tablet is associated with common side effects like hypoglycemia (low blood sugar level), nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. Its use can also lead to serious but rare side effects like lactic acidosis. On long-term use, it can also lead to vitamin B12 deficiency.

Can the use of Symet 5mg/500mg Tablet cause hypoglycemia?

Yes, the use of Symet 5mg/500mg Tablet can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate and feeling anxious or shaky. It happens more often if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with this medicine. So, regular monitoring of blood sugar level is important. Always keep a quick source of sugar like glucose tablets, honey or fruit juice with you.

Can the use of Symet 5mg/500mg Tablet lead to Vitamin B12 deficiency?

Yes, the use of Symet 5mg/500mg Tablet can cause vitamin B12 deficiency on long-term use as it interferes with the absorption of vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems and the patient may feel a tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). To avoid such problems, some researchers suggest an intake of Vitamin B12 from outside sources at least once every year.

Are there any specific conditions in which Symet 5mg/500mg Tablet should not to be taken?

The use of Symet 5mg/500mg Tablet should be avoided in patients with known allergy to any of the components or excipients of this medicine. It should also be avoided in patients with moderate to severe kidney disease and in patients with underlying metabolic acidosis including diabetic ketoacidosis.

Is it safe to take alcohol while I am also taking Symet 5mg/500mg Tablet?

No, it is not safe to take Symet 5mg/500mg Tablet along with alcohol, as it may lower your low blood sugar levels (hypoglycemia) and can increase the chances of lactic acidosis.

What are the instructions for storage and disposal of Symet 5mg/500mg Tablet?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

What is Symet 5mg/500mg Tablet?

What is type 2 diabetes?

What are the possible side effects of Symet 5mg/500mg Tablet?

The use of Symet 5mg/500mg Tablet is associated with common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. Its use can also lead to serious but rare side effects like lactic acidosis. On long-term use, it can also lead to vitamin B12 deficiency.

Can the use of Symet 5mg/500mg Tablet cause hypoglycemia?

Can the use of Symet 5mg/500mg Tablet lead to Vitamin B12 deficiency?

Are there any specific conditions in which Symet 5mg/500mg Tablet should not to be taken?

Is it safe to take alcohol while I am also taking Symet 5mg/500mg Tablet?

No, it is not safe to take Symet 5mg/500mg Tablet along with alcohol, as it may lower your low blood sugar levels (hypoglycemia) and can increase the chances of lactic acidosis.

What are the instructions for storage and disposal of Symet 5mg/500mg Tablet?

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Glucose - Postprandial Blood

Glycosylated Hemoglobin

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Glyburide and Metformin HCl Tablets [FDA Prescribing information]. Princeton, NJ: Bristol-Myers Squibb Company; 2013. [Accessed 28 Oct. 2021] (online) Available from:
Glyburide and Metformin HCl. Princeton, New Jersey: Bristol-Myers Squibb Company; 2009. [Accessed 08 Apr. 2019] (online) Available from:
Glyburide and Metformin HCl [Drug Label]. Princeton, NJ: Bristol-Myers Squibb Company; 2013. [Accessed 14 Aug. 2024] (online) Available from:

Marketer details

Name: Syskem Pharmocrats

Address: "Shree Balwant Bhawan", Below DFO Office, Forest Office Road, Solan 173212.

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.