Synclofen Plus 50mg/500mg Tablet is a pain-relieving medicine. It is used to reduce pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It may also be used to relieve muscle pain, back pain, toothache, or pain in the ear and throat.

Synclofen Plus 50mg/500mg Tablet should be taken with food. This will prevent you from getting an upset stomach. You should take it regularly as advised by your doctor. Do not take more or use it for a longer duration than recommended by your doctor.

Some of the common side effects of this medicine include nausea, vomiting, stomach pain, loss of appetite, heartburn, and diarrhea. If any of these side effects bother you or do not go away with time, you should let your doctor know. Your doctor may help you with ways to reduce or prevent the side effects.

The medicine may not be suitable for everybody. Before taking it, let your doctor know if you have any problems with your heart, kidneys, liver, or have stomach ulcers. To make sure it is safe for you, let your doctor know about all the other medicines you are taking. Pregnant and breastfeeding mothers should first consult their doctors before using this medicine.

Uses of Synclofen Tablet

Pain relief

Benefits of Synclofen Tablet

In Pain relief

Synclofen Plus 50mg/500mg Tablet is a combination of medicines that is used for short-term relief of pain, inflammation and swelling. It inhibits release of those chemical messengers in the brain that tell us that we have pain. It effectively relieves back pain, earache, throat pain, toothache and pain due to arthritis too.
Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.

Side effects of Synclofen Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Synclofen

Nausea
Vomiting
Stomach pain/epigastric pain
Heartburn
Diarrhea
Loss of appetite

How to use Synclofen Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Synclofen Plus 50mg/500mg Tablet is to be taken with food.

How Synclofen Tablet works

Synclofen Plus 50mg/500mg Tablet is a combination of two medicines: Diclofenac and Paracetamol. These medicines work by blocking the action of chemical messengers responsible for pain, fever and inflammation (redness and swelling).

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Synclofen Plus 50mg/500mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Synclofen Plus 50mg/500mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Synclofen Plus 50mg/500mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

UNSAFE

Synclofen Plus 50mg/500mg Tablet may cause side effects which could affect your ability to drive.
Synclofen Plus 50mg/500mg Tablet may cause headaches, blurred vision, dizziness or drowsiness in some patients. This may affect your ability to drive.

Kidney

CAUTION

Synclofen Plus 50mg/500mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Synclofen Plus 50mg/500mg Tablet may be needed. Please consult your doctor.

Liver

CAUTION

Synclofen Plus 50mg/500mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Synclofen Plus 50mg/500mg Tablet may be needed. Please consult your doctor.
However, the use of Synclofen Plus 50mg/500mg Tablet is not recommended in patients with severe liver disease and active liver disease.

What if you forget to take Synclofen Tablet?

If you miss a dose of Synclofen Plus 50mg/500mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Synclofen Plus 50mg/500mg Tablet

₹1.75/Tablet

Dan-P Tablet

Unison Pharmaceuticals Pvt Ltd

₹2.6/tablet

49% costlier

Duoflam N Tablet

Maneesh Pharmaceuticals Ltd

₹4.92/tablet

181% costlier

Dinax P 50 mg/500 mg Tablet

Colinz Laboratories Ltd

₹5.04/tablet

188% costlier

Clofenac P 50 mg/500 mg Tablet

Sterkem Pharma Pvt Ltd

₹1.97/tablet

13% costlier

Infla 50mg/500mg Tablet

Bajaj Pharmaceutical

₹5.24/tablet

199% costlier

View all substitutes

Quick tips

You have been prescribed this combination medicine for relieving pain and inflammation.
Take it with food to avoid getting an upset stomach.
It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
Avoid consuming alcohol when taking Synclofen Plus 50mg/500mg Tablet as it may cause excessive drowsiness and increase the risk of liver damage.
Do not take it with any other medicine containing acetaminophen (drugs for pain/fever or cough-and-cold) without asking your doctor first.

Fact Box

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Patient concerns

One of my teeth is sensitive. It some times pains

Dr. Abhijit Gambhir

Dental Surgery

sensitivity has many causative factors for relief of pain you can take pain killers it will give temporary relief

fever and 2 months pregnant can take combiflan

Dr. Sonu Balhara Ahlawat

Obstetrics and Gynaecology

No take Crocin for pain relief

FAQs

What is Synclofen Plus 50mg/500mg Tablet?

Synclofen Plus 50mg/500mg Tablet is a combination of two medicines: Diclofenac and Paracetamol. This medication helps in relieving pain and inflammation. It works by lowering the levels of chemical substances in the body that cause pain and inflammation. Paracetamol / Acetaminophen has an early onset of action which means that it takes very less time to start its action and it helps in relieving the symptoms till diclofenac starts working.

Is it safe to use Synclofen Plus 50mg/500mg Tablet?

Yes, Synclofen Plus 50mg/500mg Tablet is safe for most of the patients. However, in some patients it may cause some unwanted common side effects like nausea, vomiting, stomach pain, heartburn, diarrhea and other uncommon and rare side effects. Inform your doctor if you experience any persistent problem while taking this medication.

Can I stop taking Synclofen Plus 50mg/500mg Tablet when my pain is relieved?

Synclofen Plus 50mg/500mg Tablet, when used for long-term pain relief, should be continued for as long as advised by your physician. It can be discontinued if you are using it for short-term pain relief.

Can the use of Synclofen Plus 50mg/500mg Tablet cause nausea and vomiting?

Yes, the use of Synclofen Plus 50mg/500mg Tablet can cause nausea and vomiting. Taking it with milk, food or with antacids can prevent nausea. Avoid taking fatty or fried foods along with this medication. In case of vomiting, drink plenty of water or other fluids by taking small frequent sips. Talk to your doctor if vomiting persists and you notice signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicine without speaking to your doctor.

Can the use of Synclofen Plus 50mg/500mg Tablet cause dizziness?

Yes, the use of Synclofen Plus 50mg/500mg Tablet can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded it is better to rest for some time and resume once you feel better.

Can the use of Synclofen Plus 50mg/500mg Tablet cause damage to kidneys?

Yes, the long-term use of Synclofen Plus 50mg/500mg Tablet can cause damage to the kidneys. Normal kidneys produce a chemical called prostaglandins that protect them from damage. Use of painkillers lowers the levels of prostaglandins in the body leading to kidney damage on long-term use. Use of painkillers is not recommended in patients with underlying kidney disease.

Are there any specific contraindications associated with the use of Synclofen Plus 50mg/500mg Tablet?

The use of Synclofen Plus 50mg/500mg Tablet is considered to be harmful in patients with known allergy to painkillers (NSAIDs) or any of the components or excipients of this medicine. The use of this medicine should preferably be avoided in patients with a history of stomach ulcers or in patients with active, recurrent stomach ulcer/bleeding. It should also be avoided in patients with the history of heart failure, high blood pressure, and liver or kidney disease.

Can Synclofen Plus 50mg/500mg Tablet be taken with Vitamin B-complex?

Yes, Synclofen Plus 50mg/500mg Tablet can be taken with Vitamin B-complex preparations. While Synclofen Plus 50mg/500mg Tablet helps to relieve pain, Vitamin B-complex can help to correct the vitamin deficiency that might be causing the underlying painful condition.

Is it safe to take a higher than the recommended dose of Synclofen Plus 50mg/500mg Tablet?

No, taking a higher than the recommended dose of Synclofen Plus 50mg/500mg Tablet can lead to increased chances of side effects like nausea, vomiting, heartburn, indigestion, diarrhea and can also damage your kidneys on long-term use. If you are experiencing increased severity of pain or the pain is not relieved by the recommended doses of this medicine, please consult your doctor for re-evaluation.

What is the recommended storage condition for Synclofen Plus 50mg/500mg Tablet?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Diclofenac. Daventry, Northamptonshire: Dexcel Pharma Ltd.; 1996 [revised 20 Dec. 2017]. [Accessed 22 Apr. 2019] (online) Available from:

Marketer details

Name: Smilax Pharmaceuticals

Address: 11 Km. Stone, Tonk Road, Sanganer, Jaipur-302011 (Rajasthan).

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.