Synex 20mg Tablet DT
Prescription Required
Product introduction
Synex 20mg Tablet DT is a pain-relieving medicine. It is used to treat moderate to severe pain in conditions such as osteoarthritis and rheumatoid arthritis. It helps relieve pain and swelling in the joints and muscles.
Synex 20mg Tablet DT should be taken with food. This will prevent you from getting an upset stomach. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. You should keep taking the medicine even if you feel better until the doctor says it is alright to stop using it.
The most common side effects of this medicine include mild vomiting, stomach pain, nausea, headache, and dizziness. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.
Before using it, you should let your doctor know if you have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Pregnant and breastfeeding mothers should consult their doctors before using the medicine.
Uses of Synex Tablet DT
Benefits of Synex Tablet DT
In Pain relief
Synex 20mg Tablet DT is used for short-term relief of pain, inflammation, and swelling in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis or even after a dental (tooth-related) surgery.
Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.
Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.
Side effects of Synex Tablet DT
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Synex
- Vomiting
- Stomach pain
- Nausea
- Headache
- Dizziness
How to use Synex Tablet DT
Take this medicine in the dose and duration as advised by your doctor. Dissolve it in a glass of water before taking it. Synex 20mg Tablet DT is to be taken with food.
How Synex Tablet DT works
Synex 20mg Tablet DT is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that are responsible for inflammation (pain and swelling).
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Synex 20mg Tablet DT.
Pregnancy
CONSULT YOUR DOCTOR
Synex 20mg Tablet DT is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Synex 20mg Tablet DT is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Synex 20mg Tablet DT may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Synex 20mg Tablet DT should be used with caution in patients with severe kidney disease. Dose adjustment of Synex 20mg Tablet DT may be needed. Please consult your doctor.
Liver
CAUTION
Synex 20mg Tablet DT should be used with caution in patients with liver disease. Dose adjustment of Synex 20mg Tablet DT may be needed. Please consult your doctor.
What if you forget to take Synex Tablet DT?
If you miss a dose of Synex 20mg Tablet DT, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
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Quick tips
- Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
- Synex 20mg Tablet DT helps relieve pain and swelling of various joints and muscles.
- Take it with food to avoid stomach upset.
- Your doctor will prescribe you the lowest effective dose of this medicine for the shortest possible time necessary to relieve your symptoms.
- It may cause dizziness and fatigue. Do not drive or do anything requiring concentration until you know how it affects you.
- Avoid consuming alcohol when taking this medicine as it may cause excessive drowsiness.
Fact Box
Chemical Class
Enolic acid Derivatives
Habit Forming
No
Therapeutic Class
PAIN ANALGESICS
Action Class
NSAID's- Non-Selective COX 1&2 Inhibitors (enolic acids)
Patient concerns
User feedback
What are you using Synex Tablet DT for?
Pain relief
100%
FAQs
Q. What is the difference between Synex 20mg Tablet DT and diclofenac?
Both Synex 20mg Tablet DT and diclofenac are pain killers. However, piroxicam is a non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain) inhibitor whereas diclofenac has a bit more selectivity to a COX-2 enzyme. This selectivity of diclofenac is supposed to decrease the side effects as compared to Synex 20mg Tablet DT.
Q. What is the difference between Synex 20mg Tablet DT and naproxen?
Both Synex 20mg Tablet DT and naproxen are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, gastric side effects are lesser with naproxen as compared to Synex 20mg Tablet DT.
Q. What is the difference between Synex 20mg Tablet DT and meloxicam?
Both Synex 20mg Tablet DT and meloxicam are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, acute gastric side effects are lesser with meloxicam as compared to Synex 20mg Tablet DT.
Q. What is the difference between Synex 20mg Tablet DT and ketoprofen?
Both Synex 20mg Tablet DT and ketoprofen are pain killers. Both are non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain). Research studies have shown ketoprofen topical gel is better and effective as compared to Synex 20mg Tablet DT. Ketoprofen gel also showed excellent tolerability.
Q. What is the difference between Synex 20mg Tablet DT and tramadol?
Synex 20mg Tablet DT is a COX (cyclooxygenase -an enzyme responsible for inflammation and pain) whereas Tramadol is a narcotic-like painkiller. Tramadol is a habit forming medicine.
Q. What is the difference between Synex 20mg Tablet DT and nimesulide?
Both Synex 20mg Tablet DT and nimesulide are pain killers. However, Synex 20mg Tablet DT is a non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain) inhibitor whereas nimesulide is selective to the COX-2 enzyme. This selectivity of nimesulide is supposed to decrease the side effects as compared to piroxicam. It should not be used in children below 12 years of age.
Q. Can Synex 20mg Tablet DT be used in the treatment of chikungunya?
Usually, the platelet count does not dip in cases of chikungunya and painkillers like piroxicam can lead to the risk of increased bleeding tendency. So refrain from taking Synex 20mg Tablet DT or any painkiller in the case of any fever with joint pain. Consult your doctor before starting Synex 20mg Tablet DT.
Q. Are Synex 20mg Tablet DT and aspirin same?
No. Synex 20mg Tablet DT and aspirin are not same. They belong to the same class of drugs known as COX (cyclooxygenase) inhibitors. They both are anti-inflammatory and analgesic.
Q. Can Synex 20mg Tablet DT be used along with dexamethasone?
No. Synex 20mg Tablet DT should not be used with dexamethasone. They both increase each other's toxicity. There is an increased risk of GI ulceration.
Q. Can Synex 20mg Tablet DT be used with methocarbamol?
Yes. Methocarbamol can be used with Synex 20mg Tablet DT as no serious side effects are known. Inform your doctor before starting any of the medication.
Q. Can Synex 20mg Tablet DT be used along with paracetamol?
Yes. Paracetamol can be used with Synex 20mg Tablet DT as no serious side effects are known. Inform your doctor before starting any of the medication.
Q. Is Synex 20mg Tablet DT a NSAID?
Yes. Synex 20mg Tablet DT is a non-steroidal anti-inflammatory drug (NSAID).
Q. Is Synex 20mg Tablet DT a sulfa drug?
Synex 20mg Tablet DT is a sulphur containing compound. Synex 20mg Tablet DT can cause serious adverse events in sensitive individuals. It can cause severe skin reactions like Steven Johnson Syndrome. Do inform your doctor if you have any kind of allergies.
Q. Is Synex 20mg Tablet DT a blood thinner?
No. Synex 20mg Tablet DT is not a blood thinner. It is a pain killer. It should be avoided in a patient with a bleeding disorder.
Q. Is Synex 20mg Tablet DT a muscle relaxant?
No. Synex 20mg Tablet DT is not a muscle relaxant. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme.
Q. Is Synex 20mg Tablet DT a narcotic?
No. Synex 20mg Tablet DT is not a narcotic. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme to decrease the pain and inflammation.
Q. Can Synex 20mg Tablet DT be used in hypertension?
No. Synex 20mg Tablet DT is not a medication to control hypertension. It is important to note that Synex 20mg Tablet DT decreases the effectiveness of the antihypertensive medication when given together. Inform your doctor if you are taking antihypertensive medications before starting Synex 20mg Tablet DT.
Q. Can Synex 20mg Tablet DT be used along with Losartan?
No. Synex 20mg Tablet DT should not be combined with Losartan. It is important to note that Synex 20mg Tablet DT decreases the effectiveness of the antihypertensive medication like losartan when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Synex 20mg Tablet DT.
Q. Can Synex 20mg Tablet DT be used with Lisinopril?
No. Synex 20mg Tablet DT should be avoided with lisinopril. It is important to note that piroxicam decreases the effectiveness of the antihypertensive medication like lisinopril when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Synex 20mg Tablet DT.
Q. Can Synex 20mg Tablet DT be used with calcium channel blocker?
Yes. Synex 20mg Tablet DT can be taken with calcium channel blocker. NSAIDs have been observed to reduce the effectiveness of all antihypertensive drugs except calcium channel blockers (ref: White 2007)
Q. Can Synex 20mg Tablet DT be used with Tizanidine?
Yes, Synex 20mg Tablet DT can be combined with tizanidine. Piroxicam is a pain killer and tizanidine is a skeletal muscle relaxant. It is used in the condition like a backache.
Q. Why is beta cyclodextrin added to Synex 20mg Tablet DT?
Yes. Synex 20mg Tablet DT can be combined with beta-cyclodextrin. Research has shown that combining Synex 20mg Tablet DT with beta-cyclodextrin leads to faster onset of action of piroxicam and reduced gastric side effects.
Q. Are there any alternatives of Synex 20mg Tablet DT?
Yes. There are alternatives to Synex 20mg Tablet DT. Pain killers are prescribed according to the disease condition. Consult your doctor before starting piroxicam or changing it to other medication.
Q. What are the contraindications for Synex 20mg Tablet DT?
Contraindications to piroxicam are an allergy, bleeding tendency, duodenal/gastric/peptic ulcer, stomatitis, Systemic Lupus Erythematosus (SLE), ulcerative colitis, upper GI disease, late pregnancy, cardiac disease, hepatic impairment, renal impairment.
Q. Can Synex 20mg Tablet DT be used in the treatment of allergy?
No. Synex 20mg Tablet DT is not a drug to treat allergy. It is a pain killer.
Q. How long does Synex 20mg Tablet DT work?
Synex 20mg Tablet DT is a long acting drug. Once the daily dose is enough for the relief of pain but it depends from person to person as the effectiveness of piroxicam increases when given for few weeks.
Q. Can you get high by using Synex 20mg Tablet DT?
No. Synex 20mg Tablet DT is not known to cause high. It is a non-narcotic painkiller.
Q. Can Synex 20mg Tablet DT be used to treat menstrual cramp?
Synex 20mg Tablet DT is not approved for the treatment of menstrual cramps. Research studies have shown that piroxicam is quite effective in significantly decreasing the menstrual cramps.
Q. Can I use Synex 20mg Tablet DT for a migraine?
Synex 20mg Tablet DT is not approved for the treatment of migraine. Research studies have shown that Synex 20mg Tablet DT is effective in significantly decreasing the pain associated with migraine without aura.
Q. Is Synex 20mg Tablet DT effective in back pain management?
Yes. It can be given for decreasing the back pain. However, you should consult your doctor for the exact cause of your back pain and then start the treatment. Do not self-medicate yourself with Synex 20mg Tablet DT as the cause of back pain can be different for different person.
Q. Is Synex 20mg Tablet DT affective in gout management?
Yes. Synex 20mg Tablet DT can be given for the treatment of acute gout. Research studies have shown Synex 20mg Tablet DT to be highly effective in the treatment of acute gout.
Q. Can you donate blood when on the medication with Synex 20mg Tablet DT?
Yes. You can donate blood when on Synex 20mg Tablet DT. Do inform your doctor before donating blood.
Q. Can I use Synex 20mg Tablet DT if I am a diabetic?
Synex 20mg Tablet DT in a diabetic patient can only be taken only by consulting a doctor because these medicines have the propensity to cause renal failure when taken for a long period. Diabetes itself causes renal Synex 20mg Tablet DT so taking piroxicam can lead to increased risk of renal failure by many folds.
Q. Can I use Synex 20mg Tablet DT if I have a deranged renal function?
No. Synex 20mg Tablet DT should not be taken if you have a abnormal renal function because long-term administration of NSAIDs has resulted in renal papillary necrosis and another renal injury.
Q. Can Synex 20mg Tablet DT lead to skin reactions?
Yes. Synex 20mg Tablet DT is known to cause skin reactions which can be very severe such as exfoliative dermatitis, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal. These serious events may occur without warning. You should inform your doctor if you feel you have a mild rash and immediately discontinue the drug.
Q. Can I use Synex 20mg Tablet DT if I am pregnant?
No. Synex 20mg Tablet DT should not be taken in pregnancy. It causes premature closure of the ductus arteriosus which can lead to fetal heart failure and death of the baby.
Q. Can I use Synex 20mg Tablet DT if I have peptic ulcer disease?
No. Synex 20mg Tablet DT is contraindicated in cases of active peptic ulcer disease. Synex 20mg Tablet DT is known to cause gastric ulceration and bleeding.
Q. Can I use Synex 20mg Tablet DT if I have asthma?
Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory (NSAID) drugs like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.
Q. Can Synex 20mg Tablet DT lead to difficulty in conception?
Yes. Synex 20mg Tablet DT can sometimes cause reversible infertility. Piroxicam by its mechanism of action may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.
Q. Can Synex 20mg Tablet DT be used with diuretics?
No. Synex 20mg Tablet DT should not be used with diuretics. Synex 20mg Tablet DT reduces the natriuretic effect of furosemide and thiazides diuretics in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis.
Q. Can Synex 20mg Tablet DT be used with lithium?
No. Synex 20mg Tablet DT should not be used with lithium. Synex 20mg Tablet DT leads to an elevation of plasma lithium levels and a reduction in renal lithium clearance. This is because of inhibition of renal prostaglandin synthesis by the NSAID. Consult and inform your doctor before starting this medication.
Q. Can Synex 20mg Tablet DT be used with warfarin?
No. Synex 20mg Tablet DT should be avoided with warfarin as they both lead to increase in bleeding tendencies. Inform your doctor if you are taking any of the medications. If given together then the therapy should be monitored closely.
Q. What increases the chances of getting a gastric ulcer when I am already taking Synex 20mg Tablet DT?
The chances of gastric ulceration increases if you take medicines like corticosteroids and anticoagulants. Long term use, alcohol, smoking and old age are few other factors which can increase the chances of ulceration.
Q. Who should not take a Non-Steroidal Anti-Inflammatory Drug (NSAID)/ Synex 20mg Tablet DT?
Patients who had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID medicine or for pain right before or after heart bypass surgery.
Q. What are the serious side effects of Synex 20mg Tablet DT?
GI discomfort and, rarely, serious GI side effects, such as ulcers and bleeding, serious skin side effects such as exfoliative, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis, liver failure, renal damage.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 628.
- Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 989-90.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1127-28.
- PubChem. Piroxicam. [Accessed 02 Apr. 2019] (online) Available from:
- ScienceDirect. Piroxicam. [Accessed 02 Apr. 2019] (online) Available from:
- Piroxicam. Feb. 2015. [Accessed 02 Apr. 2019] (online) Available from:
- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 02 Apr. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:
- Piroxicam [Drug Label]. Mumbai, India: Pfizer Limited; 2022. [Accessed 06 Apr. 2024] (online) Available from:
Marketer details
Name: Syskem Pharmocrats
Address: "Shree Balwant Bhawan", Below DFO Office, Forest Office Road, Solan 173212.
Country of origin: India
The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.
The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.
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