Synotrol Tablet 400mg is used to treat increased phosphate levels in the blood. It is used in patients who are on dialysis due to severe kidney disease. It inhibits the absorption of phosphate from the intestine and lowers the phosphate levels in the blood.

Synotrol Tablet 400mg should be taken with food. Take it in the dose and duration as advised by your doctor. Take it regularly and at a fixed time each day to get the maximum benefit of the medicine.

Synotrol Tablet 400mg may cause side effects such as nausea, vomiting, abdominal pain, constipation, and diarrhea. You may also develop low levels of calcium, folic acid, and vitamins A, D, E, and K in your blood. Take necessary supplements as advised by your doctor.

Uses of Synotrol Tablet

High phosphate levels in blood

Side effects of Synotrol Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Synotrol

Abdominal pain
Diarrhea
Flatulence
Vomiting
Constipation
Nausea

How to use Synotrol Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Synotrol Tablet 400mg is to be taken with food.

How Synotrol Tablet works

Synotrol Tablet 400mg inhibits the absorption of phosphate from the intestine and lower the phosphate levels in the blood.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Synotrol Tablet 400mg. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Synotrol Tablet 400mg may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Synotrol Tablet 400mg is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

CONSULT YOUR DOCTOR

It is not known whether Synotrol Tablet 400mg alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

SAFE IF PRESCRIBED

Synotrol Tablet 400mg is safe to use in patients with kidney disease. No dose adjustment of Synotrol Tablet 400mg is recommended.
However, regular monitoring of calcium levels is advisable in these patients.

Liver

SAFE IF PRESCRIBED

Synotrol Tablet 400mg is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Synotrol Tablet 400mg may not be needed in these patients. Please consult your doctor.

What if you forget to take Synotrol Tablet?

If you miss a dose of Synotrol Tablet 400mg, skip it and continue with your normal schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Synotrol Tablet 400mg

₹21.7/Tablet

Revlamer 400 Tablet

Sun Pharmaceutical Industries Ltd

₹11.4/tablet

47% cheaper

Sevlaren 400 Tablet

La Renon Healthcare Pvt Ltd

₹22/tablet

1% costlier

Phoscut 400 Tablet

Steadfast Medishield Pvt Ltd

₹9.4/tablet

57% cheaper

Acutrol C 400 Tablet

Intas Pharmaceuticals Ltd

₹11.8/tablet

46% cheaper

Sevelam 400 Tablet

Rencord Life Sciences Pvt Ltd

₹22.8/tablet

5% costlier

View all substitutes

Quick tips

Synotrol Tablet 400mg is used to control blood phosphate level in patients that are on dialysis treatment.
You must take it with food and stick to the diet prescribed by your doctor.
You may develop low levels of calcium, folic acid, and vitamins A,D,E, and K in your blood. Your doctor may prescribe supplements, if necessary.
Avoid taking any other medicine 1 hour before or 3 hours after taking Synotrol Tablet 400mg.
Inform your doctor if you have nausea, vomiting, constipation, pain in the abdomen, or if you have undergone any major stomach surgery.
Synotrol Tablet 400mg is used to control blood phosphate level in patients that are on dialysis treatment.
You must take it with food and stick to the diet prescribed by your doctor.
You may develop low levels of calcium, folic acid, and vitamins A,D,E, and K in your blood. Your doctor may prescribe supplements, if necessary.
Avoid taking any other medicine 1 hour before or 3 hours after taking Synotrol Tablet 400mg.
Inform your doctor if you have nausea, vomiting, constipation, pain in the abdomen, or if you have undergone any major stomach surgery.

Fact Box

Chemical Class

Epoxide

Habit Forming

Therapeutic Class

BLOOD RELATED

Action Class

Phosphorous binder

Interaction with drugs

Taking Synotrol with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Sparfloxacin (Oral Route) Moderate

To take Sparfloxacin, ensure a gap of at least 1 hour before and 3 hours after taking Sevelamer. Sevelamer may reduce blood levels of Sparfloxacin.

Norfloxacin (Oral Route) Moderate

To take Norfloxacin, ensure a gap of at least 1 hour before and 3 hours after taking Sevelamer. Sevelamer may reduce blood levels of Norfloxacin.

Levofloxacin (Oral Route) Moderate

To take Levofloxacin, ensure a gap of at least 1 hour before and 3 hours after taking Sevelamer. Sevelamer may reduce blood levels of Levofloxacin.

Ciprofloxacin (Oral Route) Moderate

To take Ciprofloxacin, ensure a gap of at least 1 hour before and 6 hours after taking Sevelamer. Sevelamer may reduce blood levels of Ciprofloxacin.

Ofloxacin (Oral Route) Moderate

To take Ofloxacin, ensure a gap of at least 1 hour before and 3 hours after taking Sevelamer. Sevelamer may reduce blood levels of Ofloxacin.

View all drug interactions

Patient concerns

##High blood Uric Acid levels.

Shikha Mishra

Dietetics/Nutrition

What exactly u want to know

Blood sugar levels high suggest me

Dr. Sanjay Bhatt

Physician

A person can control his or her sugar levels by regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOU DOCTOR AND LOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you souls not treat it as disease but start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications.online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET

Blood Sugar levels high Fasting 207 PP 357 How to bring the levels down?

Dr. Sanjay Bhatt

Physician

Need to proper investigate and examine. So plz consult doctor nearby.or you can consult me at snergy multiple speciality clinic RD CITY ,BALJEET COMPLEX NEAR SRS MARKET SECTOR 52 gurgaon 9XXXXXX .Advice to maintain calories intake as per weight ,regular walk or aerobic exercises ,on time take your medicines and once a month visit your diabetologist for routine examination and investigations. Will definitely controlled your sugar and u can live healthy life.

Is Synotrol Tablet 400mg taken with food?

Yes, Synotrol Tablet 400mg can be taken with food. It is recommended to take 1-2 tablets (based on individual needs) thrice daily. It is important to take it with meals because Synotrol Tablet 400mg works by binding to phosphate from food. Take it exactly as advised by your doctor.

Can Synotrol Tablet 400mg be crushed?

No, you should not crush, chew, or break Synotrol Tablet 400mg into pieces. You should swallow it as a whole with water.

Why is it important for me to take Synotrol Tablet 400mg?

It is important to take Synotrol Tablet 400mg as patients undergoing dialysis cannot control the phosphate levels in their blood, especially after a meal. When the level of phosphate exceeds above the range in the blood, it may cause problems such as itchy skin, red eyes, high blood pressure, bone pain, and also increase the risk of fractures. These increased serum phosphate levels are reduced by Synotrol Tablet 400mg, as it binds phosphate from food in the digestive tract.

Does Synotrol Tablet 400mg cause constipation?

A common side effect of Synotrol Tablet 400mg is constipation, though it does not occur in everyone. The other common side effects of the stomach and intestine include diarrhea, indigestion, flatulence, and pain in the abdomen. Immediately consult your doctor if these side effects become severe and disturb you.

Who should not take Synotrol Tablet 400mg?

Patients who are allergic to Synotrol Tablet 400mg and who have low levels of phosphate in blood should avoid taking Synotrol Tablet 400mg. Additionally, patients having intestinal obstruction should also avoid using Synotrol Tablet 400mg.

Can I take ciprofloxacin while I am taking Synotrol Tablet 400mg?

Ciprofloxacin may interfere with the working of Synotrol Tablet 400mg and therefore it should not be taken at the same time as Synotrol Tablet 400mg. However, if taken together then a gap of at least 2 hours before or 6 hours after taking Synotrol Tablet 400mg should be maintained.

How long do I need to take Synotrol Tablet 400mg?

Continue taking Synotrol Tablet 400mg as long as recommended by your doctor. Synotrol Tablet 400mg lowers your dietary phosphate levels but does not cure your disease. Hence, you may have to take it lifelong, as stopping Synotrol Tablet 400mg may increase your phosphate levels.

Do I need to have any tests while taking Synotrol Tablet 400mg?

Yes, serum phosphate levels should be monitored regularly while you are taking Synotrol Tablet 400mg. Also, the use of Synotrol Tablet 400mg may decrease the levels of vitamin D, A, E, K, and folic acid and hence the levels need to be monitored during the treatment.

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Related lab tests

Calcium

Phosphorus, Serum

Phosphorus, Urine

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1259.
Medscape. Sevelamer. [Accessed 6 Apr. 2019] (online) Available from:
Sevelamer hydrochloride. Guildford, Surrey: SANOFI; 2000 [revised 20 Dec. 2018]. [Accessed 30 Jan. 2019] (online) Available from:
Sevelamer. Cambridge, USA: Genzyme Corporation; 1998. [Accessed 6 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 6 Apr. 2019] (online) Available from:
Sevelamer Carbonate [Product Information]. Ahmedabad, Gujarat: La Renon. [Accessed 06 Aug. 2023]. (online) Available from:
National Center for Biotechnology Information. PubChem Compound Summary for , Sevelamer. [Accessed 06 Aug. 2023]. (online) Available from:

Marketer details

Name: Agrosaf Pharmaceuticals

Address: Raman Tower, 2ND FLOOR, Sanjay Place, Agra, Uttar Pradesh 282002

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.