Synovial 50mg Tablet is a pain-relieving medicine. It is used to treat pain, swelling, stiffness, and joint pain in conditions like rheumatoid arthritis, osteoarthritis, and acute musculoskeletal injuries. It is commonly used in back pain, shoulder pain, neck pain, sprains, and spasms.

Synovial 50mg Tablet should be taken in the dose and duration as advised by your doctor. It should be taken with food or milk to prevent stomach upset. Inform your doctor if you have any history of heart disease or stroke.

The most common side effects of this medicine include nausea, vomiting, diarrhea, abdominal pain, indigestion, flatulence, decreased appetite, headache, and dizziness. Your doctor may also regularly monitor your kidney function, liver function, and levels of blood components if you are taking this medicine for long-term treatment. Long-term use may lead to serious complications such as stomach bleeding and kidney problems.

Synovial 50mg Tablet should be used with precaution in patients with asthma and cardiovascular bleeding. This medicine is contraindicated for the treatment of perioperative pain in the setting of coronary artery bypass graft (CABG) surgery. Pregnant and breastfeeding women should consult their doctors before using this medicine as it may cause harmful effects to the developing baby.

Uses of Synovial Tablet

Pain relief

Benefits of Synovial Tablet

In Pain relief

Synovial 50mg Tablet belongs to a group of medicines called nonsteroidal anti-inflammatory drugs (NSAIDs). It is used for short-term relief of pain, inflammation, and swelling in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis.

Take it as it is prescribed to get the most benefit. Do not take more or longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.

Side effects of Synovial Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Synovial

Nausea
Vomiting
Diarrhea
Abdominal pain
Indigestion
Flatulence
Headache
Dizziness
Decreased appetite
Vertigo
Rash
Increased transaminase level in blood

How to use Synovial Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Synovial 50mg Tablet is to be taken with food.

How Synovial Tablet works

Synovial 50mg Tablet is a non-steroidal anti-inflammatory drugs (NSAID). It works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling).

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Synovial 50mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Synovial 50mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Synovial 50mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Synovial 50mg Tablet may cause side effects which could affect your ability to drive.
Synovial 50mg Tablet may cause headaches, blurred vision, dizziness or drowsiness in some patients. This may affect your ability to drive.

Kidney

CAUTION

Synovial 50mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Synovial 50mg Tablet may be needed. Please consult your doctor.

Liver

CAUTION

Synovial 50mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Synovial 50mg Tablet may be needed. Please consult your doctor.

What if you forget to take Synovial Tablet?

If you miss a dose of Synovial 50mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Synovial 50mg Tablet

₹0.72/Tablet

Knac 50mg Tablet

Astra IDL MAX

₹0.51/tablet

29% cheaper

Reactin 50 Tablet

Cipla Ltd

₹1.84/tablet

156% costlier

Inac 50 Tablet

Zydus Cadila

₹2.25/tablet

212% costlier

NAC 50 Tablet

Systopic Laboratories Pvt Ltd

₹1.94/tablet

169% costlier

Jonac 50mg Tablet

Zydus Cadila

₹1.67/tablet

132% costlier

View all substitutes

Quick tips

You have been prescribed Synovial 50mg Tablet to relieve pain and inflammation.
Take it with food or milk to prevent upset stomach.
Take it as per the dose and duration prescribed by your doctor. Long term use may lead to serious complications such as stomach bleeding and kidney problems.
It may cause dizziness, drowsiness or visual disturbances. Use caution while driving or doing anything that requires concentration.
Avoid consuming alcohol while taking Synovial 50mg Tablet as it can cause excessive drowsiness and increase your risk of stomach problems.
Inform your doctor if you have a history of heart disease or stroke.
Your doctor may regularly monitor your kidney function, liver function and levels of blood components, if you are taking this medicine for long-term treatment.

Fact Box

Chemical Class

Phenylacetic acid Derivative

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Action Class

NSAID's- Non-Selective COX 1&2 Inhibitors (acetic acid)

Interaction with drugs

Taking Synovial with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Tacrolimus (Oral Route) Severe

Concurrent use may increase the risk of serious damage to the kidneys. If concurrent use is essential, your doctor may monitor your tacrolimus levels, potassium levels and kidney ... More

Methotrexate (Oral Route) Severe

Concurrent use may result in fatal Methotrexate poisoning. Careful consideration is advised when taking Methotrexate with Diclofenac. Your doctor may monitor your treatment and ad... More

Fondaparinux (Injection Route) Severe

Concurrent use may increase the risk of bleeding. If concurrent use is essential, watch out for bleeding and consult your doctor immediately.

Heparin (Injection Route) Severe

Concurrent use may increase the risk of bleeding. Diclofenac may increase the effect of Heparin. Do not consume Diclofenac with Heparin. If concurrent use is essential, your doctor... More

Methotrexate (Oral Route) Severe

Concurrent use may result in fatal Methotrexate poisoning. Careful consideration is advised when taking Methotrexate with Diclofenac. Your doctor may monitor your treatment and ad... More

View all drug interactions

Patient concerns

pain in knees,is it due to lack of synovial fluid?

Dr. Akshat Goel

Orthopaedics

Osteoarthritis of both knees Will need to undergo Knee Replacement surgery on both knees

Please inform whether synovial cancer is true?

Vipul Aggarwal

didn't get what are u asking yes cancer can present there

My mother is suffering from severe knee pain, consulted many doctors but could not find the exact reason for pain some say she has arthritis, some say synovial fluid is finished, some say that bones have become dry due to lack of synovial fluid, she had symptoms like pain in knee and below that and swelling in knee joint & ankle joint due to pain , she is not able to walk more than 10 minutes, she need to sit after every 10 minutes, seeing her symptoms i studied on net that she is suffering from bone marrow edema , osteoarthritis. Please tell me is it so? Am I right? If it is so please suggest me what is the treatment for this, if synovial fluid is less or no then how it can be made ? One thing more I want to tell we belong to middle class family we do not have much money to spend on , my parents have spend all money in making their children educated for which I m today able to write to you, so also please suggest me the best othropaedist where I can get my mother treated.

Dr. Akshat Goel

Orthopaedics

As per your description, she seems to be suffering with Osteoarthritis of both knees""She needs to avoid squatting and crossed-leg sitting and avoid all ground level activities Also use western style commode and not the indian style seat in toiletConsult a physiotherapist to do Hot Wax bath on her knees and Gentle ROM exercises and Quadriceps strengthening ExercisesAt home she needs to do Hot Fomentation and apply Dynapar QPS spray twice dailyShe can take Tab Ace-Proxyvon once or twice daily for pain reliefAlso get a Digital x-ray done of Both knees (AP view) in standing position and share it

User feedback

What are you using Synovial Tablet for?

Pain relief

100%

FAQs

Is Synovial 50mg Tablet a good painkiller?

Synovial 50mg Tablet is effective in relieving pain and inflammation. It is used for various sorts of pain such as sprains, strains and other injuries. It is also helpful in various types of arthritis, gout, pain and inflammation following surgery.

Is Synovial 50mg Tablet a narcotic?

No, Synovial 50mg Tablet is not a narcotic. It belongs to non-steroidal anti-inflammatory drugs (NSAIDs) group of medicines.

Does Synovial 50mg Tablet get you high?

No, Synovial 50mg Tablet does not get you high. It does not have an abuse potential (drug-seeking behavior) and does not cause physical or psychological dependence. However, if you do not feel well, consult your doctor.

Can Synovial 50mg Tablet damage your kidneys?

Long-term use and high doses of Synovial 50mg Tablet may cause renal problems such as protein or blood in urine and painful urination. Patients who are at maximum risk of developing kidney problems include people who are dehydrated, have heart failure, impaired kidney function, hypertension, elderly, who are on medicines which cause excess urination (diuretics), or medicines which have significant impact on kidney function. Hence, for such patients kidney function monitoring is recommended.

Does Synovial 50mg Tablet make you drowsy?

Synovial 50mg Tablet can cause drowsiness and also dizziness, fatigue (tiredness) and visual disturbances. However, it is not very common and may not affect everyone. If you experience these symptoms avoid driving or operating heavy machinery.

What is the most important information I need to know about Synovial 50mg Tablet?

It is important to know that Synovial 50mg Tablet may increase your chance of having a heart attack or stroke. The risk is more if you take higher doses and have been using the medicine for a longer time. Also, taking Synovial 50mg Tablet may cause ulcers, bleeding, or holes in your stomach and intestine. These problems may happen without warning symptoms at any time during treatment and may even cause death. Therefore, if you encounter any such problems, consult your doctor immediately.

Can Synovial 50mg Tablet be taken during pregnancy?

You should not take Synovial 50mg Tablet during the last 3 months of pregnancy as it may cause harmful effects on your baby. Use of Synovial 50mg Tablet can also lead to reduced labor (premature delivery). Hence, it is advised to avoid using Synovial 50mg Tablet during the first 6 months of pregnancy also. In some cases, Synovial 50mg Tablet may be prescribed in pregnant women only if the benefits outweigh the risks involved with its use in pregnant women. If not sure, consult your doctor regarding its use.

Show less

Top Rheumatologists

Dr. Sumeet Agrawal

MBBS, MD, DM

4.9 ★

Dr. Rajiva Gupta

MBBS, DNB, MD, Fellowship, Fellowship

4.7 ★

4.6 ★

5 ★

4.7 ★

Want to share the information?

Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 626.
Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 986-87.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 295-97.
Diclofenac. Daventry, Northamptonshire: Dexcel Pharma Ltd.; 1996 [revised 20 Dec. 2017]. [Accessed 02 Apr. 2019] (online) Available from:
Diclofenac. Rouse Boulevard, Philadelphia: Iroko Pharmaceuticals; 1998 [revised Oct. 2013]. [Accessed 02 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:
Diclofenac sodium [Prescribing Information]. East Hanover, NJ: Novartis Pharmaceuticals Corporation; 2021. [Accessed 06 Apr. 2024] (online) Available from:

Marketer details

Name: Synokem Pharmaceuticals Ltd

Address: 14/486, Sunder Vihar, Outer Ring , Road, Paschim Vihar, New, Delhi-110 087, INDIA

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.