Thyrosig 12.5mcg Tablet is a medicine used to treat an underactive thyroid gland (hypothyroidism). It replaces the hormone which is not being produced by your thyroid gland in sufficient quantity and helps regulate your body’s energy and metabolism.

Before you start taking Thyrosig 12.5mcg Tablet, your doctor will do a blood test to see what dose you need. Once you start taking the medicine, you will have regular blood tests to see how well it is working, and the dose may be adjusted from time to time. It is best taken on an empty stomach before your first meal of the day. You should take this medicine regularly to get the maximum benefit. It may take several weeks before your symptoms start to improve. You may need to take it for the rest of your life. If you stop taking it, your symptoms are likely to come back.

The most common side effects of this medicine are caused by taking a higher dose than you need. Possible side effects include palpitations (irregular heartbeat), vomiting, anxiety, diarrhea, weight loss, tremors, increased appetite, and restlessness. Most side effects will disappear once you are on the right dose. Call your doctor straight away if you have a very high temperature, fast or irregular heart rate, low blood pressure, yellowness in the eye/skin, confusion, or fits.

Thyrosig 12.5mcg Tablet may cause weight loss but should not be prescribed or taken to treat obesity. If you become pregnant while taking this medicine, inform your doctor right away as the dose may have to be increased/readjusted. Many other drugs affect the way this medicine works. Ask your doctor for advice if you are taking any other medications.

Uses of Thyrosig Tablet

Hypothyroidism

Side effects of Thyrosig Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Thyrosig

Palpitations
Vomiting
Anxiety
Diarrhea
Weight loss
Nervousness
Increased appetite
Tremors

How to use Thyrosig Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Thyrosig 12.5mcg Tablet is to be taken empty stomach.

How Thyrosig Tablet works

Thyrosig 12.5mcg Tablet is a synthetic version of a hormone produced by the thyroid gland. It works by replacing the thyroid hormones that your thyroid gland cannot produce in a sufficient quantity, and relieves the symptoms of hypothyroidism (tiredness, weight gain, and depression).

Safety advice

Alcohol

SAFE

Consuming alcohol with Thyrosig 12.5mcg Tablet does not cause any harmful side effects.

Pregnancy

SAFE IF PRESCRIBED

Thyrosig 12.5mcg Tablet is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.

Breast feeding

SAFE IF PRESCRIBED

Thyrosig 12.5mcg Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.

Driving

SAFE

Thyrosig 12.5mcg Tablet does not usually affect your ability to drive.

Kidney

CONSULT YOUR DOCTOR

There is limited information available on the use of Thyrosig 12.5mcg Tablet in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Thyrosig 12.5mcg Tablet in patients with liver disease. Please consult your doctor.

What if you forget to take Thyrosig Tablet?

If you miss a dose of Thyrosig 12.5mcg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Thyrosig 12.5mcg Tablet

₹1.26/Tablet

Thyronorm 12.5mcg Tablet

Abbott

₹1.66/tablet

32% costlier

Thyrox 12.5 Tablet

Macleods Pharmaceuticals Pvt Ltd

₹1.66/tablet

32% costlier

Lethyrox 12.5 Tablet

Intas Pharmaceuticals Ltd

₹1.36/tablet

8% costlier

Thyrotek 12.5mcg Tablet

Gonan Pharma

₹1.5/tablet

19% costlier

Thyroneed 12.5mcg Tablet

Mankind Pharma Ltd

₹1.66/tablet

32% costlier

View all substitutes

Quick tips

Thyrosig 12.5mcg Tablet should be taken on an empty stomach (ideally, first thing in the morning). No food, milk, or tea should be taken 1 hour before and 2 hours after taking this medicine.
It may take 6 to 8 weeks to get the full effect.
For most people, Thyrosig 12.5mcg Tablet can be a lifelong medication. Do not discontinue it without discussing your doctor.
Inform your doctor if you have diarrhea, nervousness, irritability, sleep disturbances, shaking hands, or chest pain. Your doctor may adjust your dose.
Leave a gap of at least 4 hours before taking any antacids, calcium or iron supplements, and multivitamins, as these may interfere with the effect of the medicine.
Get your hormone levels checked regularly and inform your doctor if you notice a significant change in your body weight. The dose may need to be adjusted.
Inform your doctor before changing the brand of Thyrosig 12.5mcg Tablet as all brands may not have the same effect.
Your doctor has prescribed Thyrosig 12.5mcg Tablet to replace the natural thyroid hormone that your own thyroid gland can no longer make.
Thyrosig 12.5mcg Tablet should be taken on an empty stomach (ideally, first thing in the morning). No food, milk, or tea should be taken 1 hour before and 2 hours after taking this medicine.
It may take 6 to 8 weeks to get the full effect.
For most people, Thyrosig 12.5mcg Tablet can be a lifelong medication. Do not discontinue it without discussing your doctor.
Inform your doctor if you have diarrhea, nervousness, irritability, sleep disturbances, shaking hands, or chest pain. Your doctor may adjust your dose.
Leave a gap of at least 4 hours before taking any antacids, calcium or iron supplements, and multivitamins, as these may interfere with the effect of the medicine.
Get your hormone levels checked regularly and inform your doctor if you notice a significant change in your body weight. The dose may need to be adjusted.
Inform your doctor before changing the brand of Thyrosig 12.5mcg Tablet as all brands may not have the same effect.

Fact Box

Chemical Class

Iodinated amino acid derivative

Habit Forming

Therapeutic Class

HORMONES

Action Class

Thyroid Hormones

Interaction with drugs

Taking Thyrosig with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Amiodarone (Oral Route) Moderate

Amiodarone may reduce blood levels of Thyroxine and its active form. Do not consume Thyroxine with Amiodarone. If concurrent use is essential, your doctor may monitor your thyroid... More

Amiodarone (Injection Route) Moderate

Amiodarone may reduce blood levels of Thyroxine and its active form. Do not consume Thyroxine with Amiodarone. If concurrent use is essential, your doctor may monitor your thyroid... More

Atazanavir (Oral Route) Moderate

Atazanavir may reduce the efficacy of Thyroxine. If concurrent use is essential, please consult your doctor, they may monitor your thyroid function closely along with your overall... More

Calcium (Oral Route) Moderate

Thyroxine may increase the effect of Calcium. Ensure a gap of at least 4 hours between taking Thyroxine and Calcium.

Allylestrenol (Oral Route) Moderate

Concurrent use may increase the requirement of Thyroxine. If concurrent use is essential, your doctor may monitor your thyroid functioning closely along with your overall treatmen... More

View all drug interactions

Patient concerns

I have affect by hypothyroidism if there any problem to get pregnant

Dr. Satyam S. Bhavsar

Physician

yes, hypothyroidism may effect fertility.

I'm suffering from hypothyroidism

Dr. Deepak Kumar Soni

Ayurveda

https://goo.gl/forms/YhGqRXe7vppuodhT2 kindly share your detail for better treatment

FAQs

What should I do if I accidentally take more than the dose required?

An overdose of this medicine may cause nervousness, anxiety, rapid heartbeat, hand tremors, excessive sweating, weight loss, and sleep problems. You should immediately consult your doctor in case of an overdose.

How long do I need to take Thyrosig 12.5mcg Tablet?

You should take Thyrosig 12.5mcg Tablet as long as your doctor has recommended. Usually, it is prescribed for the long term and you may have to take it lifelong. Do not stop taking the medicine, as your symptoms of low levels of thyroid hormone may reoccur.

How should Thyrosig 12.5mcg Tablet be taken?

Take Thyrosig 12.5mcg Tablet exactly as advised by your doctor. Thyrosig 12.5mcg Tablet should be taken orally preferably before breakfast or as a first meal of the day. It should be swallowed whole with plenty of water.

Being a diabetic what should I be aware of while taking Thyrosig 12.5mcg Tablet?

Thyrosig 12.5mcg Tablet may raise blood sugar levels and may affect the working of other anti-diabetic medicines which you might be taking. Hence, dose adjustment may be required. Consult your doctor who will help you with dose management.

What does thyroxine do? Why is it important?

Thyroxine hormone controls how much energy your body uses. It plays an important role in regulating your body weight, muscle strength, body temperature, and even your mood. Along with that, it is important for your digestion, heart muscles, brain development, and bone health.

Does Thyrosig 12.5mcg Tablet affect contraception?

Oral birth control pills, which contain both estrogen and progesterone may reduce the amount of Thyrosig 12.5mcg Tablet in your body and therefore the dose of Thyrosig 12.5mcg Tablet may have to be increased.

Show less

Related lab tests

Anti Thyroglobulin Antibody

Thyroid Function Test

Thyroid Profile Free

Thyroid Stimulating Hormone

Want to share the information?

Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Brent GA, Koenig RJ. Thyroid and Anti-Thyroid Drugs. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1142-43.
Dong BJ, Greenspan FS. Thyroid & Antithyroid Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 674-75.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 796-98.
Levothyroxine sodium. East Sussex, UK: Custom Pharmaceuticals Ltd.; 2018. [Accessed 04 Apr. 2019] (online) Available from:
Levothyroxine. Bohemia, New York: Jerome Stevens Pharmaceuticals, Inc. [Accessed 04 Apr. 2019] (online) Available from:
Levothyroxine [Prescribing Information]. Morgantown, WV: Mylan Pharmaceuticals Inc.; 2022. [Accessed 07 Aug. 2023]. (online) Available from:

Marketer details

Name: Signova Pharma Pvt Ltd

Address: House No-44, Ground Floor, Barthakur Mill Road, Ulubari, Guwahati, Kamrup,Assam, PIN -781007

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.