Topgraf 0.1% Ointment
Prescription Required
Product introduction
Topgraf 0.1% Ointment is used to treat eczema (atopic dermatitis). It works by suppressing the activity of certain immune cells that cause inflammation (redness and swelling) of the skin. This relieves itching and improves rashes in atopic dermatitis.
Topgraf 0.1% Ointment is used for external use. It should be used 2-4 times a day on the affected area or use it as suggested by the doctor. It should be applied slowly and evenly to the skin until it is rubbed in. You should not use it too often and you should not cover the treated area with a bandage or plaster. You must inform your doctor if there’s no improvement even after two weeks of treatment or if the skin gets worse.
Use of this medicine may cause some common side effects like erythema, headache, inflammation of hair follicle, and application site reaction like burning, irritation, itching, and redness. This medicine is not normally recommended during pregnancy or while breastfeeding unless it is clearly needed.
Topgraf 0.1% Ointment is used for external use. It should be used 2-4 times a day on the affected area or use it as suggested by the doctor. It should be applied slowly and evenly to the skin until it is rubbed in. You should not use it too often and you should not cover the treated area with a bandage or plaster. You must inform your doctor if there’s no improvement even after two weeks of treatment or if the skin gets worse.
Use of this medicine may cause some common side effects like erythema, headache, inflammation of hair follicle, and application site reaction like burning, irritation, itching, and redness. This medicine is not normally recommended during pregnancy or while breastfeeding unless it is clearly needed.
Uses of Topgraf Ointment
Benefits of Topgraf Ointment
In Treatment of Atopic dermatitis
Atopic dermatitis, also known as eczema, is a chronic skin condition causing red, itchy, and inflamed patches on the skin, often associated with allergies. Topgraf 0.1% Ointment when applied topically suppresses the immune response in the skin, reducing the inflammatory reactions that lead to eczema flare-ups. This way it provides relief and helps improve the quality of life for individuals with atopic dermatitis.
Side effects of Topgraf Ointment
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Topgraf
- Application site reactions (burning, irritation, itching and redness)
- Headache
- Hair follicle inflammation
How to use Topgraf Ointment
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and gently massage the ointment.
How Topgraf Ointment works
Topgraf 0.1% Ointment is an immunosuppressant. It works by suppressing the activity of certain immune cells that cause inflammation (redness and swelling) of the skin. This relieves itching and improves rashes in atopic dermatitis.
Safety advice
Alcohol
No interaction found/established
Pregnancy
CONSULT YOUR DOCTOR
Topgraf 0.1% Ointment may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Topgraf 0.1% Ointment is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
No interaction found/established
Kidney
No interaction found/established
Liver
No interaction found/established
What if you forget to take Topgraf Ointment?
If you miss a dose of Topgraf 0.1% Ointment, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule.
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For informational purposes only. Consult a doctor before taking any medicines.
Topgraf 0.1% Ointment
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Quick tips
- Topgraf 0.1% Ointment is effective at treating eczema (atopic dermatitis) when other treatment options have failed.
- It works by decreasing itching, redness, and skin rashes.
- Apply thinly, to affected areas of skin only. Clean the affected area and dry well before applying Topgraf 0.1% Ointment. Avoid contact with water after application.
- Inform your doctor if there's no improvement even after two weeks of treatment, or if the skin gets worse.
- Don't cover the area being treated with airtight dressings such as bandages unless directed by a doctor, as this may increase the risk of side effects.
- Stop using Topgraf 0.1% Ointment and consult your doctor if your eczema becomes infected.
- Continuous long-term use of the ointment should be avoided. Use as prescribed by you doctor.
Fact Box
Chemical Class
Macrolide Lactams
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Immunosuppressant- Calcineurin inhibitors
Patient concerns
User feedback
Patients taking Topgraf 0.1% Ointment
Once A Day
100%
What are you using Topgraf Ointment for?
Others
80%
Atopic dermat*
20%
*Atopic dermatitis
How much was the improvement?
Poor
47%
Average
40%
Excellent
13%
What were the side-effects while using Topgraf 0.1% Ointment?
Application s*
33%
Increased glu*
33%
No Side Effec*
33%
*Application site reactions (burning, irritation, itching and redness), Increased glucose level in blood, No Side Effect
How do you take Topgraf Ointment?
With or witho*
67%
With food
33%
*With or without food
Please rate Topgraf 0.1% Ointment on price
Expensive
42%
Not Expensive
33%
Average
25%
FAQs
What is Topgraf 0.1% Ointment used for?
Topgraf 0.1% Ointment is a medicine that modulates the immune system. It works on the immune system and mostly decreases its activity. It is used to treat moderate to severe eczema (atopic dermatitis) in adults who do not respond to steroids or develop side effects on using them. In atopic dermatitis, the skin’s immune system undergoes an overreaction and causes skin inflammation leading to itchiness, redness and dryness. Topgraf 0.1% Ointment acts on the abnormal immune response and alters it, thereby relieving the skin inflammation and itchiness.
What are the side effects of Topgraf 0.1% Ointment?
Topgraf 0.1% Ointment, when applied to the skin, may cause skin irritation, burning sensation and itching at the site of application. These are usually mild to moderate in severity and normally resolve within one week of starting the treatment. Redness is also a common manifestation along with sensation of warmth, pain, altered sensation and rash at the site of application. Using it increases the patients’ increased risk of getting inflamed or infected hair follicles, cold sores, acne and generalized herpes simplex infections.
Is Topgraf 0.1% Ointment ointment safe?
As compared to other immune-suppressing medicines, Topgraf 0.1% Ointment has been found to be a safe and effective short-term treatment for atopic dermatitis. When applied on the affected part of the skin, its absorption to the blood and body is minimal. Hence, the side effects are less as compared to when taken through oral route.
Does Topgraf 0.1% Ointment has abuse potential?
No, Topgraf 0.1% Ointment does not have abuse potential and thus, is not a controlled substance. Controlled substances have potential for abuse so they need permission by authorities and doctor for use.
Does Topgraf 0.1% Ointment cause cancer?
Long-term use of Topgraf 0.1% Ointment has been found to have increased risk of lymph node tumors called lymphoma. Some studies have found that few patients who used Topgraf 0.1% Ointment ointment or another similar medication developed skin cancer or lymphoma. Consult your doctor if you have to use Topgraf 0.1% Ointment ointment for more than 6 weeks or if your eczema symptoms have not improved or are getting worse with time during your treatment.
Is Topgraf 0.1% Ointment a steroid?
No, Topgraf 0.1% Ointment is not a steroid. It is a medicine which modulates the working of the immune system. It is used in the treatment of eczema, most commonly in atopic dermatitis. An advantage of Topgraf 0.1% Ointment is that it does not cause skin thinning (atrophy) or other steroid-related side effects.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Burkhart C, Morrell D, Goldsmith L. Dermatological Pharmacology. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1822.
- Lake DF, Briggs AD, Akporiaye ET. Immunopharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 972.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1305-309.
- Tacrolimus monohydrate. Hurley, Berkshire: Leo Laboratories Limited; 2002 [revised 30 Jun. 2018]. [Accessed 17 Apr. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 06 Apr. 2019] (online) Available from:
- Tacrolimus [Prescribing Information]. Dublin 12, Ireland: LEO Laboratories Ltd.; 2022. [Accessed 01 Aug. 2023]. (online) Available from:
Marketer details
Name: Glaxo SmithKline Pharmaceuticals Ltd
Address: Dr. Annie Besant Road, Mumbai - 400 030
Country of origin: India
The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.
The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.
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