Toplift XL 75mg Capsule SR
Prescription Required
Product introduction
Toplift XL 75mg Capsule SR is used in the treatment of depression and anxiety disorder. It alters the chemicals in the brain that cause symptoms of anxiety such as irritability, restlessness, lack of concentration, fatigue, sweating, increased heart rate, and unwanted or racing thoughts.
Toplift XL 75mg Capsule SR should be taken with food. It is advised to take this medicine at a fixed time each day to maintain a consistent level in the blood. If you miss any doses, take it as soon as you remember. Do not skip any doses and finish the full course of treatment even if you feel better. This medication mustn't be stopped suddenly as it may worsen your symptoms.
Some common side effects of this medicine include nausea, vomiting, insomnia (difficulty in sleeping), decreased appetite, anxiety, constipation, increased sweating, and sexual dysfunction. It may cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. However, these side effects are temporary and usually resolve on their own in some time. Please consult your doctor if these do not subside or bother you.
Before taking Toplift XL 75mg Capsule SR, inform your doctor if you have any problems with your kidneys, heart, liver, or have a history of seizures (epilepsy or fits). Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or if you have any suicidal thoughts.
Toplift XL 75mg Capsule SR should be taken with food. It is advised to take this medicine at a fixed time each day to maintain a consistent level in the blood. If you miss any doses, take it as soon as you remember. Do not skip any doses and finish the full course of treatment even if you feel better. This medication mustn't be stopped suddenly as it may worsen your symptoms.
Some common side effects of this medicine include nausea, vomiting, insomnia (difficulty in sleeping), decreased appetite, anxiety, constipation, increased sweating, and sexual dysfunction. It may cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. However, these side effects are temporary and usually resolve on their own in some time. Please consult your doctor if these do not subside or bother you.
Before taking Toplift XL 75mg Capsule SR, inform your doctor if you have any problems with your kidneys, heart, liver, or have a history of seizures (epilepsy or fits). Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or if you have any suicidal thoughts.
Uses of Toplift XL Capsule SR
Side effects of Toplift XL Capsule SR
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Toplift XL
- Nausea
- Vomiting
- Dizziness
- Insomnia (difficulty in sleeping)
- Decreased appetite
- Anxiety
- Constipation
- Increased sweating
- Sexual dysfunction
How to use Toplift XL Capsule SR
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Toplift XL 75mg Capsule SR is to be taken with food.
How Toplift XL Capsule SR works
Toplift XL 75mg Capsule SR works by increasing the levels of chemical messengers (serotonin and noradrenaline), natural substances in the brain that help maintain mental balance.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Toplift XL 75mg Capsule SR.
Pregnancy
CONSULT YOUR DOCTOR
Toplift XL 75mg Capsule SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Toplift XL 75mg Capsule SR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Babies should be monitored for excessive sleepiness and adequate weight gain.
Babies should be monitored for excessive sleepiness and adequate weight gain.
Driving
UNSAFE
Toplift XL 75mg Capsule SR may cause side effects which could affect your ability to drive.
As side effects of Toplift XL 75mg Capsule SR are dizziness, confusion and eye sight changes such as blurred vision and this may affect your ability to drive.
As side effects of Toplift XL 75mg Capsule SR are dizziness, confusion and eye sight changes such as blurred vision and this may affect your ability to drive.
Kidney
CAUTION
Toplift XL 75mg Capsule SR should be used with caution in patients with kidney disease. Dose adjustment of Toplift XL 75mg Capsule SR may be needed. Please consult your doctor.
Liver
CAUTION
Toplift XL 75mg Capsule SR should be used with caution in patients with liver disease. Dose adjustment of Toplift XL 75mg Capsule SR may be needed. Please consult your doctor.
What if you forget to take Toplift XL Capsule SR?
If you miss a dose of Toplift XL 75mg Capsule SR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
- Toplift XL 75mg Capsule SR helps in treating depression and anxiety.
- It may take 2 to 4 weeks for Toplift XL 75mg Capsule SR to start working. Keep taking it as prescribed.
- It may cause dizziness and sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
- Avoid consuming alcohol when taking Toplift XL 75mg Capsule SR as it may cause excessive drowsiness and increase the risk of liver damage.
- It may cause a sensation of restlessness, especially when you first start taking it. Inform your doctor if this happens to you.
- Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
- Do not stop taking the medication suddenly without talking to your doctor.
- Toplift XL 75mg Capsule SR helps in treating depression and anxiety.
- It may also be used to treat nerve pain from diabetes and some other forms of chronic pain.
- It may take 2 to 4 weeks for Toplift XL 75mg Capsule SR to start working. Keep taking it as prescribed.
- It may cause dizziness and sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
- Avoid consuming alcohol when taking Toplift XL 75mg Capsule SR as it may cause excessive drowsiness and increase the risk of liver damage.
- It may cause an increase in blood pressure, especially during the first month of treatment. Monitor your blood pressure regularly.
- It may cause a sensation of restlessness, especially when you first start taking it. Inform your doctor if this happens to you.
- Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
- Do not stop taking the medication suddenly without talking to your doctor.
Fact Box
Chemical Class
Anisole Derivative
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Serotonin Norepinephrine Reuptake Inhibitors (SNRIs)
Interaction with drugs
Taking Toplift XL with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concomitant use may cause an increase in blood serotonin levels. Patients may experience agitation, increased body temperature, fast heartbeat, muscle rigidity, and loss of coordin
Concomitant use may cause an increase in blood serotonin levels. Patients may experience agitation, increased body temperature, fast heartbeat, muscle rigidity, and loss of coordin
Concomitant use may affect heart rhythm and can be fatal.
Do not consume Venlafaxine with Domperidone.
Concurrent use may cause fatal rise in blood serotonin levels.
Avoid concurrent use unless your doctor considers it safe.
Concurrent use may cause serotonin syndrome.
If concurrent use is essential, watch out for symptoms of serotonin syndrome such as tremors, fever, diarrhea or agitation and consult
Patient concerns
FAQs
Can Toplift XL 75mg Capsule SR cause sedation?
Yes. Toplift XL 75mg Capsule SR can cause sedation. You should inform your doctor if you are taking any other sleep inducing medicines before starting Toplift XL 75mg Capsule SR.
Is Toplift XL 75mg Capsule SR a psychotropic drug?
Yes. Toplift XL 75mg Capsule SR is a psychotropic drug. Any medication capable of affecting the mind, emotions, and behaviour are called psychotropic drugs.
Is Toplift XL 75mg Capsule SR a narcotic?
No. Toplift XL 75mg Capsule SR is not a narcotic drug. Narcotics are drugs with sleep inducing properties, usual derivatives of Opium like Heroin and Morphine.
What is the difference between Toplift XL 75mg Capsule SR ER and XR?
Both are same medication. Toplift XL 75mg Capsule SR ER and XR both means extended release preparation which releases the medication slowly into the body and maintains a constant needed medications levels. The advantage of taking ER/XR tablets is the frequency of dosage can be decreased.
Can I take mirtazapine along with Toplift XL 75mg Capsule SR?
No. There can be a serious side effect when mirtazapine is taken with Toplift XL 75mg Capsule SR. It can cause a serious condition called as serotonin syndrome. It is a potentially life-threatening can present as agitation, hallucinations, nausea, vomiting, diarrhoea, tachycardia, labile blood pressure, hyperthermia and coma.
Can I take Toplift XL 75mg Capsule SR with citalopram?
No. Citalopram and Toplift XL 75mg Capsule SR both increase serotonin levels. Avoid or use any alternate drug. It can cause a serious condition called as serotonin syndrome. It is a potentially life-threatening can present as agitation, hallucinations, nausea, vomiting, diarrhoea, tachycardia, labile blood pressure, hyperthermia and coma.
What is the relation between Toplift XL 75mg Capsule SR and p-glycoprotein?
P-glycoprotein is responsible for the expulsion of Toplift XL 75mg Capsule SR from the brain. Some studies have shown that Toplift XL 75mg Capsule SR and its metabolite inhibit the p-glycoprotein.
Where is Toplift XL 75mg Capsule SR absorbed?
Toplift XL 75mg Capsule SR is absorbed from the intestine after being metabolised by the liver.
When should I take Toplift XL 75mg Capsule SR?
Toplift XL 75mg Capsule SR is a medication to treat generalised depressive disorder or depression. Consult your doctor before taking this medication.
Can Toplift XL 75mg Capsule SR cause high blood pressure?
Toplift XL 75mg Capsule SR treatment is associated with sustained increases in blood pressure in some people. It is recommended that people who are being treated with Toplift XL 75mg Capsule SR should have regular monitoring of blood pressure. For such people, either dose reduction or discontinuation should be considered.
Can Toplift XL 75mg Capsule SR cause constipation?
Yes. Toplift XL 75mg Capsule SR is known to cause constipation in some patients. Take a fiber-rich diet and drink plenty of water. You may consider taking laxatives as well. Your doctor will suggest ways to prevent or manage it. Please consult your doctor if it does not resolve or gets worse.
Can Toplift XL 75mg Capsule SR cause weight loss?
Yes. Toplift XL 75mg Capsule SR is known to cause weight loss in some patients. In research studies, a dose-dependent weight loss was noted in patients treated with Toplift XL 75mg Capsule SR for several weeks. Please consult your doctor if it bothers you.
Can Toplift XL 75mg Capsule SR cause addiction?
No. Toplift XL 75mg Capsule SR does not have habit-forming potential.
Can I take Toplift XL 75mg Capsule SR tablet instead of a capsule?
You can take a tablet instead of the capsule but only under consultation or prescription of a doctor. You should not change it yourself as the different formulation of a medication may have a different action as drug release would be different in both. This can lead to an inappropriate treatment and may lead to side effects or even failure of treatment.
Can gabapentin be given along with Toplift XL 75mg Capsule SR?
Yes. Gabapentin can be given with Toplift XL 75mg Capsule SR but only with a consultation of a doctor. They both, when given together, causes an increase drowsiness, sleepiness and decreased concentration in work. Take with caution.
What is the difference between Toplift XL 75mg Capsule SR and desvenlafaxine?
Desvenlafaxine is an active metabolite of Toplift XL 75mg Capsule SR. It is the same medication in an active form.
Can fibromyalgia be treated with Toplift XL 75mg Capsule SR?
Toplift XL 75mg Capsule SR is not approved for the treatment of fibromyalgia. Some research studies have shown promising results of Toplift XL 75mg Capsule SR in the treatment of fibromyalgia. Consult your doctor before starting this medication.
Can nerve pain be treated with Toplift XL 75mg Capsule SR?
Toplift XL 75mg Capsule SR is not approved for treatment of nerve pain disorders but some researchers have proved its efficacy in nerve pain. It is currently used off-label for nerve pain.
Why does Toplift XL 75mg Capsule SR cause loss of appetite?
Toplift XL 75mg Capsule SR is known to cause changes in the neurotransmitters levels and chemicals in the brain which leads to decrease in appetite and this loss of appetite is dose dependent.
What are good alternatives to Toplift XL 75mg Capsule SR, particularly when a side effect is reduced sex drive?
If you find any side effects like decreased sex drive or impotence talk to your doctor and then you can have some other drug. Do not stop Toplift XL 75mg Capsule SR by yourself it can lead to increased adverse effects.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Stahl SM, editor. Venlafaxine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 721-26.
- DeBattista C. Antidepressant Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 513.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1466.
- Venlafaxine [FDA Label]. Marietta, GA: Urban Pharmaceuticals Inc.; 1993 [revised Jun. 2014]. [Accessed 19 Mar. 2019] (online) Available from:
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Venlafaxine. [Updated 2019 Oct 23]. [Accessed 20 Feb. 2020] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:
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Name: Ishjas Pharma Pvt Ltd
Address: X-936 GALI NO. 3, CHAND MOHALLA OPP. GBS SCHOOL GHANDHI NAGAR DELHI DL 110031 INDIA
Country of origin: India
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