Tosif O Syrup is an antibiotic medicine that treats bacterial infections that may affect your child’s eyes, ears, nose, throat, lungs, skin, bone and joints, gastrointestinal tract, and urinary tract. It can also be used in treating typhoid fever in children and adolescents.

Give Tosif O Syrup to your child orally, preferably at a fixed time, either before or after meals. In case your child develops a stomach upset, prefer giving it with meals. The dose and duration depend upon the type and severity of the infection, your child’s age, and body weight, so stick to the dose, time, and way prescribed by the doctor. If your child vomits within 30 minutes of intake, repeat the same dose but do not double dose if it's time for the next dose.

Do not give this medicine to your child in case of cold and flu symptoms. Such symptoms are almost always a result of viral infections, and antibiotics are ineffective in killing viruses. Antibiotics are given in cough and flu symptoms only when the doctor detects any underlying secondary bacterial infection.

This medicine may have some minor and temporary side effects such as vomiting, diarrhea, nausea, abdominal pain, and allergy. These side effects will disappear once your child’s body adapts to the medicine. However, if they persist or become bothersome for your child, report to the doctor without any delay.

Share your child’s complete medical history with your child’s doctor. Make sure the doctor knows if your child has or had any previous episode of allergy, heart problem, a blood disorder, birth defects, airway obstruction, lung anomaly, gastrointestinal problem, skin disorder, liver impairment, and kidney malfunction. This information is critical for dose alterations and for planning your child’s overall treatment.

Uses of Tosif O Syrup in children

Benefits of Tosif O Syrup for your child

In Typhoid fever

Typhoid fever spreads through the intake of contaminated food and water. Children who have typhoid and do not require hospital admission can be well managed with Tosif O Syrup at home because of its excellent activity against organisms that cause typhoid fever.

In Treatment of Bacterial infections

Tosif O Syrup is a combination of two different antibiotics that work together, in different ways, to treat various bacterial infections. Cefixime works by stopping the growth of bacteria and kills them. Ofloxacin prevents multiplication and repair of infection causing bacteria and prevents further spread of the infection.

This combination medicine can be used to treat many different bacterial infections such as ear, sinus, throat, lung, urinary tract, skin and soft tissues. It usually makes you feel better within a few days, but you should continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and do not become resistant.

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Side effects of Tosif O Syrup in children

Tosif O Syrup does not pose serious side effects and is well-tolerated by children. In case the side effects do occur, they’re likely to subside once the body adapts to the medicine. Consult your child’s doctor if these side effects persist or bother your child. The most common side effects include-

Common side effects of Tosif O

Loss of appetite
Allergy

How can I give Tosif O Syrup to my child?

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Tosif O Syrup is to be taken with food.

How Tosif O Syrup works

Tosif O Syrup contains two antibiotics. Cefixime works by preventing the formation of the bacterial protective covering (cell wall) while ofloxacin directly interacts with the genetic material of bacteria. As a consequence, the infection-causing bacteria stop growing further and the spread of the infection is successfully arrested.

Safety advice

Kidney

SAFE IF PRESCRIBED

Tosif O Syrup is safe to use in patients with kidney disease. No dose adjustment of Tosif O Syrup is recommended.
However, consult with your child’s doctor before giving Tosif O Syrup to your child in case of a severe form of liver disease.

Liver

CAUTION

Tosif O Syrup should be used with caution in patients with liver disease. Dose adjustment of Tosif O Syrup may be needed. Please consult your doctor.

What if I forget to give Tosif O Syrup to my child?

Unless your child’s doctor has advised a specific regime for your child, you can give the missed dose as soon as you remember. Skip the missed dose if it is almost time for the next dose. Do not give the double dose to catch up and follow the prescribed dosing schedule.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Tosif O Syrup

₹43.6/Syrup

Soncef O Syrup

Alson Pharma Private Limited

₹64.9/syrup

44% costlier

Fixinex O Syrup

Bionexa Organic

₹74.65/syrup

66% costlier

Escefon-O Syrup

Esquire Drug House

₹70/syrup

56% costlier

Saracef O Syrup

Sara Remedies

₹130/syrup

189% costlier

Castrov-O Syrup

Aden Healthcare

₹85/syrup

89% costlier

Quick tips

Your child must complete the entire course of antibiotics. Stopping too soon may cause the bacteria to multiply again, become resistant, or cause another infection.
Give this medicine with food to avoid an upset stomach.
Encourage your child to drink plenty of water in case diarrhea develops as a side effect.
Do not give any calcium, magnesium, iron, vitamin, or antacid within 2 hours of taking Tosif O Syrup as these can affect the absorption of the medicine.
Conditions like common cold and flu are caused by viruses. Never use this medicine for such conditions.
Only give Tosif O Syrup to your child for their current infection. Never save medicine for future illnesses.
Stop this medicine and immediately report to your child’s doctor in case your child develops an itchy rash, facial swelling, or breathing difficulties while taking this medicine.

Fact Box

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Patient concerns

My child verry high cough and fever in cold sesion try to much doctor but result is no . It's will be countiue cough and fever it's good to be only antiboitic

Dr. Gopal Bansilal Samdani

Paediatrics

Antibiotics are required if bacterial infections. Consult child specialist

Scar on face due to bacterial infections

Dr. Atul Jain

Dermatology

Pic is not clear, plz visit for proper opinion

Fever 15 days & typhoid urine i Fever 15 days & typhoid urine infection

Dr. Gopal Bansilal Samdani

Paediatrics

Monitor temperature of Patient. If Patient has fever place a cool, damp washcloth on your child's forehead. Give your Patient a lukewarm tub bath or a sponge bath. Give a sponge bath as follows: - ? Use lukewarm water [90?F (32.2?C) to 95?F (35?C)]. Do not use cold water, ice, or rubbing alcohol, which will lower the child's body temperature too quickly. ? Sponge for 20 to 30 minutes. ? Stop if the child starts to shiver. If your child doesn't like the sponge bath or doesn't feel better after the bath, there is no need to give another one. You can use paracetamol also along with above measures to control fever till you consult Dr. will determine underlying disorders by clinical examination which range from mild conditions to the most serious of bacterial and viral illnesses and will prescribe medicines accordingly

FAQs

What if I give too much of Tosif O Syrup by mistake?

An extra dose of Tosif O Syrup is unlikely to do harm. However, you must still be vigilant because overdoses may cause unwanted side effects and may even worsen your child’s condition. If you think you have given too much of Tosif O Syrup to your child, speak to a doctor immediately.

Are there any possible serious side effects of Tosif O Syrup?

Some serious side effects of this medicine include persistent vomiting, kidney damage, allergy, diarrhea, and severe gastrointestinal infections. Always consult your child’s doctor for help in such a situation.

Can other medicines be given at the same time as Tosif O Syrup?

Tosif O Syrup can sometimes interact with other medicines or substances. Tell your doctor about any other medicines your child is taking before starting Tosif O Syrup. Also, check with your child’s doctor before giving any medicine to your child.

Can I get my child vaccinated while on treatment with Tosif O Syrup?

Antibiotics usually do not interfere with the ingredients in vaccines or cause a bad reaction in a child who has just been vaccinated. However, children taking antibiotics should not get vaccinated until they recover from the illness. As soon as your child feels better, the vaccine can be given.

Can Tosif O Syrup impact my child’s digestion?

Children often have a sensitive stomach and develop a stomach upset while taking antibiotics. When antibiotics are given, the medicine may kill off the good bacteria along with the bad ones, increasing the risk of developing other infections. In case your child is having diarrhea while on Tosif O Syrup, do not stop the medicine course. Instead, call your child’s doctor to ask about the next steps. In some cases, the doctor may alter the dose.

Can Tosif O Syrup lead to bacterial resistance in my child?

Yes, the infection-causing bacteria can become resistant to Tosif O Syrup because of irregular dosing, unrequired repeated use, and misuse of Tosif O Syrup can lead to resistance. Resistant bacteria are no longer killed by the antibiotics and may lead to reinfection.

What should I tell the doctor before giving Tosif O Syrup to my child?

Inform the doctor if your child is suffering from heart disease, genetic disorders involving blood vessels, seizures, psychiatric disorders, diabetes, photoallergy (allergy from sunlight), neuromuscular disorders, or rheumatoid arthritis. This is because there is a possibility that Tosif O Syrup may aggravate these conditions and result in complications.

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Related lab tests

Complete Blood Count

Peripheral Smear Examination

Typhi Dot

Widal Test (Slide Agglutination)

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Tiwaskar M. Cefixime-ofloxacin Combination in the Management of Uncomplicated Typhoid Fever in the Indian Community Setting. J Assoc Physicians India. 2019;67(3):75-80. [Accessed 29 Jan. 2021] (online) Available from:
Healthy Children. Antibiotic Prescriptions for Children: 10 Common Questions Answered. [Accessed 29 Jan. 2021] (online) Available from:
Mayo Clinic: Drugs and Supplements. Cefixime (Oral Route). [Accessed 29 Jan. 2021] (online) Available from:
Nationwide Children’s. Cefixime oral suspension. [Accessed 29 Jan. 2021] (online) Available from:
University of Michigan: C.S. Mott Children’s Hospital. Ofloxacin. [Accessed 29 Jan. 2021] (online) Available from:

Marketer details

Name: Avunu Life Sciences

Address: Plot No. 295, Second Floor, Industrial Area Phase 2, Panchkula- 134113, Haryana, India

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.