Tosin D 0.4mg/0.5mg Tablet is a combination of two medicines that work in different ways to treat men with an enlarged prostate gland. It helps to relieve symptoms such as difficulty urinating or needing to go to the toilet more often. It is not used to prevent prostate cancer.

Tosin D 0.4mg/0.5mg Tablet may be taken with or without food but it should be taken at the same time each day. Your doctor will prescribe the dose most suitable for you. To gain the most benefit and to treat your symptoms effectively, you should not miss doses, even if you feel well. It may take up to 4 weeks to notice an improvement in the symptoms but keep taking them regularly. Tell your doctor if your symptoms do not improve after 4 weeks or if they get worse.

The most common side effects of this medicine include impotence, decreased libido, breast pain, and ejaculation disorder. If these side effects worry you or do not go away, call your doctor for advice. You may also feel dizzy or drowsy. These risks are higher when you first start taking this drug. Remember, your doctor has given you this medicine because the benefits are greater than the risks of the side effects.

Tosin D 0.4mg/0.5mg Tablet should not be taken by women or children. Before taking it, tell your doctor if you have low blood pressure or liver or kidney disease. This medicine may not be suitable. It can also affect, or be affected by, other drugs. So let your doctor know all the other medicines you are taking. You may be advised to wear a condom during sex if your partner is or may be pregnant. Your doctor may recommend getting your blood pressure checked frequently. Avoid drinking alcohol as it can cause excessive dizziness with this medicine.

Uses of Tosin D Tablet

Treatment of Benign prostatic hyperplasia

Benefits of Tosin D Tablet

In Treatment of Benign prostatic hyperplasia

When your prostate gland becomes enlarged it can cause urinary problems such as difficulty passing urine and a need to go to the toilet frequently or urgently. It can also cause urine flow to be slower. If not treated, there is a risk that your urine flow will be completely blocked. Tosin D 0.4mg/0.5mg Tablet is a combination of two medicines: dutasteride and tamsulosin. Dutasteride reduces the size of your prostate by blocking the production of a hormone which causes it to grow. Tamsulosin works by relaxing muscles in the bladder and prostate. Together they can rapidly relieve the symptoms and make it easier for you to urinate. However, it may take up to 6 months to notice the full benefit. Take this medicine exactly as prescribed for maximum benefits.

Side effects of Tosin D Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Tosin D

Impotence
Decreased libido
Ejaculation disorder
Orthostatic hypotension (sudden lowering of blood pressure on standing)
Breast enlargement in male
Breast tenderness in male
Dizziness

How to use Tosin D Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tosin D 0.4mg/0.5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Tosin D Tablet works

Tosin D 0.4mg/0.5mg Tablet is a combination of two medicines: Tamsulosin and Dutasteride, which relieves the symptoms of benign prostatic hyperplasia. Tamsulosin is an alpha-blocker. It works by relaxing the muscle around the bladder exit and prostate gland so as to allow easy passage of urine. Dutasteride is a 5-alpha-reductase inhibitor which helps in shrinking the prostate gland by decreasing the level of the hormone which helps the prostate gland grow.

Safety advice

Alcohol

UNSAFE

Tosin D 0.4mg/0.5mg Tablet may cause excessive drowsiness with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Information regarding the use of Tosin D 0.4mg/0.5mg Tablet during pregnancy is not available. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Tosin D 0.4mg/0.5mg Tablet during breastfeeding is not available. Please consult your doctor.

Driving

UNSAFE

Tosin D 0.4mg/0.5mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CONSULT YOUR DOCTOR

There is limited information available on the use of Tosin D 0.4mg/0.5mg Tablet in patients with kidney disease. Please consult your doctor.

Liver

CAUTION

Tosin D 0.4mg/0.5mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Tosin D 0.4mg/0.5mg Tablet may be needed. Please consult your doctor.
Use of Tosin D 0.4mg/0.5mg Tablet is not recommended in patients with severe liver disease.

What if you forget to take Tosin D Tablet?

If you miss a dose of Tosin D 0.4mg/0.5mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Tosin D 0.4mg/0.5mg Tablet

₹17.3/Tablet

Normpro Tablet

Goddres Pharmaceuticals Pvt Ltd

₹22.9/tablet

32% costlier

Flokind D 0.4mg/0.5mg Tablet

Mankind Pharma Ltd

₹14.3/tablet

17% cheaper

Urilosin D Tablet

Leeford Healthcare Ltd

₹11.8/tablet

32% cheaper

Tamsukem D 0.4mg/0.5mg Tablet

Alkem Laboratories Ltd

₹32.6/tablet

88% costlier

Urigrow-D Tablet

Broadspectrum Remedies Private Limited

₹25.2/tablet

46% costlier

View all substitutes

Quick tips

You have been prescribed Tosin D 0.4mg/0.5mg Tablet to relieve the symptoms of benign prostatic hyperplasia (BPH).
Take it approximately 30 minutes after the same meal each day.
Tosin D 0.4mg/0.5mg Tablet may cause dizziness or blurring of vision. Do not drive or do anything requiring concentration until you know how it affects you.
To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
If you are scheduled to undergo an eye surgery due to cataract or glaucoma, inform your eye doctor about the usage of Tosin D 0.4mg/0.5mg Tablet.
It may cause difficulty achieving or maintaining an erection (impotence), decreased sex drive, and ejaculation disorders such as decreased amount of semen produced or decreased sperm count.
Do not donate blood for 6 months after taking the last dose of Tosin D 0.4mg/0.5mg Tablet.

Fact Box

Habit Forming

Therapeutic Class

UROLOGY

Patient concerns

What is hyperplasia nd wht a treatment

Dr. Banashree Majumdar

Dermatology

Mr. PATIENT is not a medical condition, it's just a histological term mentioned in pathology reports

Sir please advice PSA very rise

Dr. Vijay Sharnangat

Medical Oncology and Hematology

It's benign enlargement of prostate

FAQs

Q. Is Tosin D 0.4mg/0.5mg Tablet effective?

Tosin D 0.4mg/0.5mg Tablet is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using Tosin D 0.4mg/0.5mg Tablet too early, the symptoms may return or worsen.

Q. Can the use of Tosin D 0.4mg/0.5mg Tablet cause dizziness?

Yes, the use of Tosin D 0.4mg/0.5mg Tablet can cause dizziness. Tosin D 0.4mg/0.5mg Tablet contains a combination of Tamsulosin and Dutasteride. Tamsulosin can cause a sudden fall in blood pressure while changing posture from lying to sitting or standing (orthostatic hypotension). This sudden fall in blood pressure can cause dizziness, lightheadedness, fainting, sensation of spinning and vertigo. If you feel dizzy or lightheaded, do not drive or use any machines. It is better to rest for some time and resume once you feel better.

Q. What are the cautions associated with the use of Tosin D 0.4mg/0.5mg Tablet?

The use of Tosin D 0.4mg/0.5mg Tablet is considered to be harmful for men under the age of 18 years as it may affect the normal development of the male reproductive tract. The use of this medicine is also considered to be harmful for patients with any known allergy to any of the components of this medicine and in women who are pregnant or of childbearing potential. Along with that, it is important to keep in mind that pregnant women should not even handle Tosin D 0.4mg/0.5mg Tablet as the medicine may get absorbed through the skin and cause harm to the fetus.

Q. Is Tosin D 0.4mg/0.5mg Tablet safe?

Tosin D 0.4mg/0.5mg Tablet is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.

Q. Can I take a higher than the recommended dose of this medicine?

No, Tosin D 0.4mg/0.5mg Tablet should be taken in the recommended dose only. An overdose of Tosin D 0.4mg/0.5mg Tablet can increase the risks of side effects. Always take your medicines according to the dose and duration prescribed by your doctor.

Q. What is the storage condition for Tosin D 0.4mg/0.5mg Tablet?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Q. Can the use of Tosin D 0.4mg/0.5mg Tablet cause ejaculation problems?

Retrograde ejaculation (semen does not leave the body, instead goes into the bladder) and ejaculation failure (reduced or absent ejaculation volume) are common problems associated with the use of Tosin D 0.4mg/0.5mg Tablet. But this is harmless and more commonly seen when the medicine is consumed in high doses.

Q. Can the use of Tosin D 0.4mg/0.5mg Tablet cause priapism (persistent painful penile erection unrelated to sexual activity)?

Yes, the use of Tosin D 0.4mg/0.5mg Tablet can cause priapism (painful penile erection). It is a serious but rare side effect associated with the use of this medicine. However, in some cases, it can lead to permanent impotence if not treated immediately.

Q. Can the use of Tosin D 0.4mg/0.5mg Tablet have any impact on my cataract surgery?

Use of Tosin D 0.4mg/0.5mg Tablet can cause floppy eye syndrome. In this, the muscles of the iris become floppy and the pupil constricts unexpectedly during cataract surgery. So, when the eye surgeon actually needs a dilated pupil, the pupil constricts unexpectedly. This restricts the field of surgery because of which the surgical outcomes can get affected. Inform your eye doctor (ophthalmologist) if you are taking this medicine or in case you have used this medicine in the last 9 months.

Q. Apart from taking medicines, what should I do to manage my prostate symptoms?

Simple lifestyle changes can help you manage your prostate symptoms better. Try to urinate when you first get the urge. However, take care not to strain or push while urinating. Avoid drinking fluids (especially alcohol, caffeine) a few hours before bedtime or going out. You should also avoid medicines which tend to worsen urinary symptoms like some over-the-counter medicines for cold and cough.

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References

CiplaMed. Tamsulosin hydrochloride + Dutasteride [Accessed 25 Apr. 2019] (online) Available from:

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The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.