Totnist 0.4mg Tablet is an alpha-adrenergic antagonist that is used in the treatment of benign prostatic hyperplasia. It helps to relieve symptoms like difficulty in passing urine. However, it does not decrease the size of the prostate.

Totnist 0.4mg Tablet is advised to take it in a dose and duration as per prescription. It may be taken with or without food, but take at the same time regularly. Swallow the medicine as a whole without crushing or chewing it. You should not stop taking the medicine without consulting the doctor as it may lead to the worsening of your symptoms. The course of the treatment should be completed for better efficacy of the medicine.

Use of this medicine can cause some common side effects such as dizziness, backe pain, chest pain, ejaculation disorder, and retrograde ejaculation. If any of the side effects persist or bother you, you must consult the doctor without delay.

Simple lifestyle changes can help you manage your symptoms better. Try to urinate as soon as you feel the urge, however, never strain or push to empty your bladder. You should avoid drinking caffeinated or alcoholic drinks at night and a few hours before going to bed or going out.

Before receiving the treatment, inform your doctor if you are on any medication for any other health condition. If you have to undergo eye surgery due to cataracts or glaucoma then inform your eye doctor about the usage of this medicine. Patients with liver disease must be cautious while receiving the prescription, and they must receive regular follow-ups as per the doctor’s advice.

Uses of Totnist Tablet

Treatment of Benign prostatic hyperplasia

Benefits of Totnist Tablet

In Treatment of Benign prostatic hyperplasia

When your prostate gland becomes enlarged it can cause urinary problems such as difficulty passing urine and a need to go to the toilet frequently or urgently. It can also cause urine flow to be slower. If not treated, there is a risk that your urine flow will be completely blocked. Totnist 0.4mg Tablet works by relaxing muscles in the bladder and prostate. So, it can rapidly relieve the symptoms and make it easier for you to urinate. However, it may take up to 6 months to notice the full benefit. Take this medicine exactly as prescribed for maximum benefits.

Side effects of Totnist Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Totnist

Chest pain
Inflammation of the nose
Dizziness
Ejaculation disorder
Headache
Abdominal pain
Back pain
Nausea
Infection

How to use Totnist Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Totnist 0.4mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Totnist Tablet works

Totnist 0.4mg Tablet is an alpha blocker. It works by relaxing the muscles around the bladder exit and prostate gland so urine is passed more easily. This helps empty the bladder completely and reduces the need to pass urine frequently or urgently in BPH.

Safety advice

Alcohol

UNSAFE

Totnist 0.4mg Tablet may cause excessive drowsiness with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Information regarding the use of Totnist 0.4mg Tablet during pregnancy is not available. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Totnist 0.4mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Totnist 0.4mg Tablet is not indicated for use in women.

Driving

SAFE

Totnist 0.4mg Tablet does not usually affect your ability to drive.

Kidney

SAFE IF PRESCRIBED

Totnist 0.4mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Totnist 0.4mg Tablet is recommended.
However, limited information is available on the use of Totnist 0.4mg Tablet in patients with end stage kidney disease. Please consult your doctor.

Liver

CAUTION

Totnist 0.4mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Totnist 0.4mg Tablet may be needed. Please consult your doctor.

What if you forget to take Totnist Tablet?

If you miss a dose of Totnist 0.4mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Totnist 0.4mg Tablet

₹6.3/Tablet

Uritin 0.4mg Tablet

Overseas Healthcare Pvt Ltd

₹14.7/tablet

133% costlier

Consistam 0.4mg Tablet

Salud Care India Pvt Ltd

₹8.7/tablet

38% costlier

Temsunol Tablet

Knoll Pharmaceuticals Ltd

₹11.9/tablet

89% costlier

Tamsukem 0.4 Tablet

Alkem Laboratories Ltd

₹17.33/tablet

175% costlier

Urise 0.4 Tablet

Shilpex Pharmysis

₹10.6/tablet

68% costlier

View all substitutes

Quick tips

Totnist 0.4mg Tablet helps in relieving the symptoms of enlarged prostate. It does not decrease the size of the prostate.
Totnist 0.4mg Tablet must be taken with food.
You will feel better within hours or days of starting the treatment. Full effect is usually seen within 2 weeks.
Totnist 0.4mg Tablet may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
If you are scheduled to undergo an eye surgery due to cataract or glaucoma, inform your eye doctor about the usage of Totnist 0.4mg Tablet.
Inform your doctor if you have ever been diagnosed with kidney or liver problems.

Fact Box

Chemical Class

Sulfonamide Derivative

Habit Forming

Therapeutic Class

UROLOGY

Action Class

Uroselective adrenergic receptor(α1a) antagonist

Interaction with drugs

Taking Totnist with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Allylestrenol (Oral Route) Moderate

Concurrent use may weaken the blood pressure-lowering effect of Tamsulosin. Monitor your blood pressure regularly and talk to your doctor if you notice any unusual symptoms. Your ... More

Baclofen (Oral Route) Moderate

Concurrent use may cause low blood pressure. If concurrent use is essential, watch out for symptoms such as dizziness, fainting, blurred vision, nausea, fatigue, confusion, cold o... More

Dapoxetine (Oral Route) Moderate

Concurrent use may increase the risk of a sudden drop in blood pressure and temporary loss of consciousness. Monitor your blood pressure regularly and talk to your doctor if you n... More

Sildenafil (Oral Route) Moderate

Concurrent use may cause a significant fall in blood pressure when standing up suddenly from a sitting position. If concurrent use is essential, your doctor may monitor your treat... More

Amlodipine (Oral Route) Moderate

Concurrent use may cause low blood pressure. If you experience dizziness, fatigue, or sweating, lie down until the symptoms abate.

View all drug interactions

Patient concerns

What is hyperplasia nd wht a treatment

Dr. Banashree Majumdar

Dermatology

Mr. PATIENT is not a medical condition, it's just a histological term mentioned in pathology reports

Sir please advice PSA very rise

Dr. Vijay Sharnangat

Medical Oncology and Hematology

It's benign enlargement of prostate

FAQs

What is the best time to take Totnist 0.4mg Tablet?

You can take the capsule after breakfast or after the first meal of the day. However, some doctors prefer it to be taken at night time after dinner. You should take it approximately 30 minutes following the same meal every day. Swallow it as a whole with a glass of water. Do not open, crush or chew the medicine.

Can the use of Totnist 0.4mg Tablet increase blood sugar levels?

Use of Totnist 0.4mg Tablet does not increase your blood sugar levels. If you notice any change in the blood sugar levels while taking it, consult your doctor as this could be due to some condition which needs attention.

Does Totnist 0.4mg Tablet cause weight gain?

No, Totnist 0.4mg Tablet does not usually cause any increase in the weight, even on long-term use. If you experience any weight gain while taking the medication, then consult your doctor to identify the cause of the weight gain.

When does Totnist 0.4mg Tablet start to work?

An improvement in urine flow can be seen in 4 to 8 hours after taking Totnist 0.4mg Tablet. However, it may take 2 to 4 weeks for the full effect to come.

Can I take Totnist 0.4mg Tablet with vitamin D?

Yes, Totnist 0.4mg Tablet can be taken with vitamin D. No harmful effects or interactions have been reported when these are used together.

How does Totnist 0.4mg Tablet help in removal of kidney stones?

In patient with kidney stones, Totnist 0.4mg Tablet helps in removal of stones via urine. It works by relaxing the muscles of the urinary tract which causes an easy removal of the stones.Use of Totnist 0.4mg Tablet in kidney stones also decreases the need for painkillers.

Why does Totnist 0.4mg Tablet cause dizziness?

Totnist 0.4mg Tablet dilates the blood vessels and leads to the accumulation of blood in the extremities (ends of the arms and limbs). This restrains the proper flow of blood to the brain, thereby causing the blood pressure to fall on the sudden change in posture. As a result, the patient may experience dizziness, lightheadedness, fainting, spinning sensation, and vertigo.

Why should I stop taking Totnist 0.4mg Tablet before my cataract surgery?

Totnist 0.4mg Tablet can cause floppy eye syndrome in which the muscles of the iris become floppy and the pupil constricts unexpectedly during cataract surgery. So, when the eye surgeon actually needs a dilated pupil, it will constrict and restrict the field of surgery, and can affect the surgical outcomes.

Why does Totnist 0.4mg Tablet cause stuffy nose?

Totnist 0.4mg Tablet relaxes the smooth muscles of the blood vessels and this vasodilation of the blood vessels can cause a stuffy nose.

Is Totnist 0.4mg Tablet anticholinergic?

No, Totnist 0.4mg Tablet is not an anticholinergic medication. It is a medicine that acts by relaxing the muscles in the prostate gland and neck of the urinary bladder, improving the urine flow in patients with benign enlargement of the prostate gland. Taking anticholinergic drugs in this condition or while taking Totnist 0.4mg Tablet can increase the symptoms and worsen the condition.

Can Totnist 0.4mg Tablet cause frequent urination?

No, Totnist 0.4mg Tablet does not cause frequent urination. In fact, this medicine increases the urine flow and decreases the urge to urinate frequently, which is a symptom of benign enlargement of the prostate gland. This condition also leads to a weak stream while urinating and hence the patient is not able to empty the bladder completely. Totnist 0.4mg Tablet is used to treat all such symptoms related to urine flow in patients with benign enlargement of the prostate gland.

What are the long-term effects of taking Totnist 0.4mg Tablet?

Usually Totnist 0.4mg Tablet does not cause any side effects in patients with benign enlargement of the prostate gland. However, long-term use of Totnist 0.4mg Tablet may increase the chances of having infection, rhinitis, pain, and pharyngitis. Its long-term use may also cause abnormal ejaculation, blackouts, faintness, lightheadedness, dizziness, and decreased blood pressure.

Apart from taking medicines, what should I do to manage my prostate symptoms?

Simple lifestyle changes can help you manage your symptoms better. Try to urinate when you first get the urge. However, take care not to strain or push to empty your bladder. Avoid drinking fluids (especially alcohol, caffeine) a few hours before bedtime or going out. Also, you should not take any other medicine without consulting your doctor because some medicines can increase your urge to urinate.

Can I take Totnist 0.4mg Tablet with ibuprofen or paracetamol?

Totnist 0.4mg Tablet can be taken with ibuprofen or paracetamol. No harmful side effects or other interactions have been seen when they are taken together.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

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Robertson D, Biaggioni I. Adrenoreceptor Antagonists Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 153.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1314.
Tamsulosin. Guildford, Surrey: Zentiva; 2017 [revised 29 Aug. 2018]. [Accessed 04 Apr. 2019] (online) Available from:
Tamsulosin.Tokyo, Japan: Astellas, Pharma Inc; 2005. [Accessed 04 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). Tamsulosin hydrochloride. [Accessed 04 Apr. 2019] (online) Available from:
CiplaMed. Tamsulosin hydrochloride [Prescribing Information]. [Accessed 07 Aug. 2023]. (online) Available from:

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