Totonin 0.05% Cream is a form of vitamin A that is used to treat acne which appears as spots or pimples on your face, chest, or back. It also helps to smooth rough facial skin and to reduce fine wrinkles on the skin.

Totonin 0.05% Cream reduces excessive oil production of the skin. Ideally, a pinpoint application at nighttime is recommended for the duration prescribed by your doctor. The amount you need and for how long you need to take it will depend on what you are being treated for. You should normally wash and dry the affected area before applying a thin layer of this medicine. Follow your doctor’s instructions. You should not apply it to damaged or broken skin and avoid contact with your mouth, eyes, and nose. It may take several weeks for your symptoms to improve but keep using it regularly to get the most benefit. Consult your doctor again if you do not notice any improvement after a few weeks. Using more medicine or applying it more often than prescribed will not make it work any faster and may increase the side effects.

The most common side effects include irritation, dryness, and redness of the skin. They are usually mild and improve as your body gets used to the medicine. Drink plenty of water and use moisturizer as it may lead to dryness of the mouth, lips, and eyes. Let your doctor know if these side effects bother you or do not go away. Serious side effects with this medicine are rare.

This medicine may make you more sensitive to sunlight so you should limit exposure to the sun if possible. It may make your skin more fragile. It is advised, not to have any waxing (hair removal), or laser treatments during treatment. Pregnant women or women who are planning to get pregnant should not use this medicine as it can lead to birth defects.

Uses of Totonin Cream

Treatment of Acne
Acute promyelocytic leukaemia

Benefits of Totonin Cream

In Treatment of Acne

Totonin 0.05% Cream is a form of vitamin A. It helps treat acne by clearing skin pores and preventing spots or pimples from appearing. It usually takes several weeks to have a noticeable effect so keep using it even if it appears not to be working. Sometimes acne may get worse before it gets better, however, with proper use, your skin will get clearer. The earlier you start using it, the less likely you are to get scars. This medicine will help improve your mood and uplift your confidence as your skin becomes acne-free. It should not be used if you have eczema or sunburned skin.

Side effects of Totonin Cream

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Totonin

Erythema (skin redness)
Skin irritation
Dry skin
Dry lips
Pale red skin
Increased sensitivity to light

How to use Totonin Cream

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.

How Totonin Cream works

Totonin 0.05% Cream is a form of vitamin A. When applied on the skin, it reduces oil production in the skin, replenishes acne-prone skin, and helps keep your pores open.

Safety advice

Alcohol

No interaction found/established

Pregnancy

CONSULT YOUR DOCTOR

Totonin 0.05% Cream may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Totonin 0.05% Cream is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

No interaction found/established

Kidney

No interaction found/established

Liver

No interaction found/established

What if you forget to take Totonin Cream?

If you miss a dose of Totonin 0.05% Cream, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Totonin 0.05% Cream

₹7.33/gm of Cream

Tretin 0.05% Cream

Hegde and Hegde Pharmaceutical LLP

₹7.3/gm of cream

same price

Tronin 0.05% Cream

Talent India

₹3.88/gm of cream

47% cheaper

Tronin 0.05% Cream

Talent India

₹5.8/gm of cream

21% cheaper

Retino-A 0.05% Cream

Janssen Pharmaceuticals

₹12/gm of cream

64% costlier

Tretinec A 0.05% Cream

Dermo Care Laboratories

₹4/gm of cream

45% cheaper

View all substitutes

Quick tips

You have been prescribed Totonin 0.05% Cream for the treatment of acne.
Clean the affected area with water and a non-medicated soap. Let it dry for 20-30 minutes before applying Totonin 0.05% Cream.
It may increase the severity of the spots or pimples in the first few weeks of use. Continue using it as prescribed by your doctor.
It may cause a stinging sensation or a feeling of warmth when you first start using it. Inform your doctor if this persists.
Avoid exposure to sunlight while using Totonin 0.05% Cream as it increases the sensitivity of your skin. Use protective measures such as sunscreen or protective clothing.
Avoid face waxing and laser treatment while using this medicine as it makes your skin more fragile.
Avoid taking tetracycline (e.g. doxycycline) as it may reduce the Totonin 0.05% Cream activity.
Do not use Totonin 0.05% Cream if you are pregnant.
Inform your doctor if excessive skin dryness or skin sensitivity takes place.
Do not use Totonin 0.05% Cream if you are pregnant.
Inform your doctor if excessive skin dryness or skin sensitivity takes place.

Fact Box

Chemical Class

Retinoids

Habit Forming

Therapeutic Class

DERMA

Action Class

Retinoids- First generation

Interaction with drugs

Taking Totonin with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Betamethasone (Oral Route) Mild

Betamethasone may reduce efficacy of Tretinoin. Talk to your doctor if you notice any unusual symptoms.Doctor may monitor your blood sugar level.

Betamethasone (Injection Route) Mild

Betamethasone may reduce efficacy of Tretinoin. Talk to your doctor if you notice any unusual symptoms.Doctor may monitor your blood sugar level.

View all drug interactions

Patient concerns

Acute case of acne on face(cheeks)

Dr. Atula Gupta

Dermatology

Treatment for Acne/Pimples:-Aclind Gel / Faceclin Gel / D?ACNE Plus gel for application twice daily over affected area. For Marks (spots) - DUCRAY Photoscreen Depigment Cream / Demelan cream for application once in a week at night (very little over marks only) For face wash Rejuglow Facewash/ Episoft OC Cleanser/ Saslic DS Wash. Tab. Limcee 500mg once daily for one month. Tab. Ascazin twice daily for one month. Combination peels can be performed by a dermatologist in order to improve pimples , marks and scars . Blood test for serum Insulin Fasting (F) & Postprandial (PP)

Is there anything related to blood cancer sir/madam??

Dr. Vijay Sharnangat

Medical Oncology and Hematology

For that we need to do bone marrow aspiration, flow cytometry.CBC suggestive of chronic Leukaemia soEven if it is Leukaemia, it will need not to be treated as it is asymptomatic in majority of times.

What is the cause of enlarge spleen and liver? What treatment to be given? What precautions should be taken? Problem has got repeated in 2 months

Dr. Gopal Bansilal Samdani

Paediatrics

Please consult Dr. will take detail history and will examine your child in detail All information will be used to determine exact underlying cause of problem. Depending upon cause will prescribe you treatment.There are many causes of liver and spleen enlargementfew examples--Infection: Acute viral hepatitis. Infectious mononucleosis. Haematological disease: Myeloproliferative disease. Leukaemia. Metabolic disease: Niemann-Pick disease. Chronic liver disease and portal hypertension: Chronic active hepatitis. Amyloidosis. Acromegaly. Systemic lupus erythematosus. Sarcoidosis.

I hv a little erectile dysfunction. I am a hairy cell leukaemia survivor. I am totally cured now. Can I use sidenafill citrate (Generic Viagra). If yes, what should be the dosage??

Dr. Shyam Gupta

Obstetrics and Gynaecology

Hello PATIENT to 1mg. Erectile problems can be happen to people at any age having issue like stress, fatigue, disturb relationship, anxiety, alcohol, smoking and medical problems like High BP, Diabetes, obesity etc. My personal advice is lifestyle changes like exercising, losing weight, stopping smoking,curbing alcohol intake, don't wear tight pants, do pelvic kegal exercise. There are medications but they have side effects so i dont advice first. But i strongly recommend to start healthy life with some antioxidant vitamins and healthy diet. You may take vitamin like DHEA cap, L arginine and herbal ashwagandha capsule. Apply Himcolin gel. Concentrate on Yoga and meditation and also take help from your partner. Use these for couple of months if not improved do few blood tests like thyroid, sugar and testosterone and let me know.

FAQs

Can I undergo cosmetic procedures while taking Totonin 0.05% Cream?

Your doctor will decide whether you can continue taking or stop taking Totonin 0.05% Cream before cosmetic procedures. However, it is advised to not undergo hair removal or laser treatments while using Totonin 0.05% Cream. Please inform your doctor about all the medicines you are taking before starting the treatment with this medicine. Also, consult the doctor before starting any cosmetic procedure.

Is it safe to use Totonin 0.05% Cream?

Yes, Totonin 0.05% Cream is safe to use when taken as advised by your doctor. However, like all medicines, even this medicine has some side effects, but it is not necessary that anyone who is taking these medicines might get these side effects. Please talk to your doctor if you get any unpleasant effects while taking this medicine.

How long am I supposed to use Totonin 0.05% Cream?

Your doctor will decide the duration of your treatment depending on the severity of your disease and the results of your lab tests. Usually, the treatment with Totonin 0.05% Cream takes around 4-5 months.

I am taking Totonin 0.05% Cream. What should I do if I am planning to become pregnant?

It is important to consult your doctor if you are planning to become pregnant while taking Totonin 0.05% Cream. Ideally, pregnancy is not advised because this medicine can harm your baby. However, if you do get pregnant during the treatment with Totonin 0.05% Cream, consult your doctor.

Why does Totonin 0.05% Cream cause dry skin, dry lips and dry nose? How to manage these?

One of the most common side effects of Totonin 0.05% Cream includes dryness of skin, nose and lips. Totonin 0.05% Cream reduces the secretion of oil which results in skin dryness. Dryness due to Totonin 0.05% Cream can be managed by applying moisturizers or lubricants like Vaseline. You can also apply lip balm to relieve cracked and dry lips. Drink enough water to keep our body hydrated.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Burkhart C, Morrell D, Goldsmith L. Dermatological Pharmacology. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1810.
Sardana K, Madan A. How to Treat Acne. Sardana K, editor. In: Clinical Approach to Acne Vulgaris. 1st ed. New Delhi: CBS Publishers & Distributors Pvt. Ltd.; 2015. pp. 35-36.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1395-98.
Tretinoin. Manati, Puerto Rico: Janssen Ortho LLC; 1997 [revised Jan. 2014]. [Accessed 03 Apr. 2019] (online) Available from:
Drugs.com. Tretinoin Topical Pregnancy and Breastfeeding Warnings. [Accessed 03 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 03 Apr. 2019] (online) Available from:

Marketer details

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Address: 110, Industrial Area, Phase 2, Panchkula Haryana, Panchkula Industrial Area Phase 2, Panchkula - 134113 (Map)

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.