Tpvalpro Tablet is a combination of two medicines used to treat epilepsy, a neurological disorder in which there are recurrent episodes of seizures or fits. It controls the abnormal activity of the brain, relaxes the nerves and hence, prevents seizures or fits.
Tpvalpro Tablet should be taken with food. Your doctor will decide the correct dose for you. This may increase gradually until your condition is stable. This medicine may take several weeks to work but it is important to take it regularly to get the benefit. Do not stop taking it, even if you feel fine unless your doctor advises you to. You may have more seizures, or your bipolar disorder may get worse.
The most common side effects of this medicine are nausea and tremor. In some people, it may also cause other side effetcs like vomiting, headache, liver injury, and upper abdominal pain. Most side effects wear off, but if they bother you or do not go away, tell your doctor. There may be ways of preventing or reducing these effects.
Before taking this medicine, tell your doctor if you have kidney or liver problems, meningitis or depression or suicidal thoughts. Also let your doctor know about all other medications you are using as some may affect, or be affected by, this medicine, including contraceptive pills. If you are pregnant or breastfeeding, Tpvalpro Tablet can be taken if it is clearly needed but the dose may be adjusted. You should avoid driving or riding a bicycle if this medicine makes you drowsy or dizzy. You may need frequent blood tests to check how you are responding to this medicine.
You should avoid alcohol while taking Tpvalpro Tablet, as it may worsen certain side effects. This medicine can also lead to weight gain, eat a healthy balanced diet, avoid snacking with high-calorie food, and exercise regularly. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
Tpvalpro Tablet slows down electrical signals in the brain which cause seizures (fits). It can also help reduce symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety. The medicine can allow you to do some activities that you would otherwise be forbidden or scared to do (such as swimming and driving). It can take a few weeks for this medicine to work (because the dose has to be increased slowly) and during this time you may still have seizures. Do not stop using this medicine even if you feel well, until your doctor advises you to. Missing doses may trigger a seizure.
Side effects of Tpvalpro Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Tpvalpro
Nausea
Tremors
How to use Tpvalpro Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tpvalpro Tablet is to be taken with food.
How Tpvalpro Tablet works
Tpvalpro Tablet is a combination of two antiepileptic medicines: Sodium Valproate and Valproic Acid.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Tpvalpro Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Tpvalpro Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Tpvalpro Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
Tpvalpro Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Tpvalpro Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Tpvalpro Tablet may not be needed in these patients. Please consult your doctor. However, talk to your doctor if you have any underlying kidney disease.
Liver
CAUTION
Tpvalpro Tablet should be used with caution in patients with liver disease. Dose adjustment of Tpvalpro Tablet may be needed. Please consult your doctor. Use of Tpvalpro Tablet is not recommended in patients with severe liver disease and active liver disease.
What if you forget to take Tpvalpro Tablet?
If you miss a dose of Tpvalpro Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
You have been prescribed Tpvalpro Tablet for treatment and prevention of seizures.
Take it at the same time every day to maintain consistent levels in your body.
Do not drive or do anything that requires mental focus until you know how Tpvalpro Tablet affects you.
Avoid consuming alcohol when taking Tpvalpro Tablet, as it may cause excessive sleepiness or drowsiness.
Monitor your weight during the treatment as Tpvalpro Tablet can cause weight gain.
Your doctor may monitor Tpvalpro Tablet level, blood counts and liver function regularly throughout your treatment. Inform your doctor if you develop fever, stomach pain, nausea or yellowing of your eyes or skin.
Do not take Tpvalpro Tablet if you are pregnant or planning to conceive or breastfeeding.
Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.
Fact Box
Habit Forming
No
Therapeutic Class
NEURO CNS
Patient concerns
3-4 attack of strokes in 3 yrs nothing found in CT scan & EEG.these tests are done again after 3 months. But nothing found. Doctors prescribed me Oxetol 450 mg.doctor say course of medicine is 2-3 yrs.I drink and smoke addicted to drug I don't understand if the test show nothing then why strokes happens to me?
Dr. Vikas Sharma
Neurology
is it stroke or epilepsy; as u are on medicine for epilepsy
My mother has got faint today. After that we have taken her to emergency Dr. has checked and opt for CT scan head. And report is normal. Only focal calcification seen in left frontal lobe. Please tell me?this is ok or any thing to worry.
My child have sudden upnormal contion above 8 years.we checked local doctors and they said its a silent fits its not cure .where we go this speclasit doctor around tamilnadu.we are poor family so kind u correct treatment
Can the use of Tpvalpro Tablet cause sleepiness or drowsiness?
Yes, Tpvalpro Tablet may make you feel drowsy or sleepy. Avoid driving, operating machinery, working at heights or participating in potentially dangerous activities. Inform your doctor if you experience such an episode while taking this medicine.
Can I drink alcohol while taking Tpvalpro Tablet?
No, avoid drinking alcohol while taking Tpvalpro Tablet. Drinking alcohol will increase the side effects caused by Tpvalpro Tablet.
Can Tpvalpro Tablet be stopped when epilepsy symptoms are relieved?
No, Tpvalpro Tablet should be continued as advised by the doctor. Stopping Tpvalpro Tablet suddenly may cause the symptoms to reappear that too with increased frequency. If any problems are experienced due to Tpvalpro Tablet, consult the doctor for re-evaluation.
Will a higher than the recommended dose of Tpvalpro Tablet be more effective?
No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having serious side effects and toxicity. If the recommended doses do not relieve your symptoms or there is an increased severity of your symptoms, please consult your doctor.
What are the instructions for the storage and disposal of Tpvalpro Tablet?
Keep this medicine in the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
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References
Linde M, Mulleners WM, Chronicle EP, et al. Valproate (valproic acid or sodium valproate or a combination of the two) for the prophylaxis of episodic migraine in adults. Cochrane Database Syst Rev. 2013;(6):CD010611. [Accessed 23 Apr. 2019] (online) Available from:
Drugs.com. Sodium Valporate. [Accessed 23 Apr. 2019] (online) Available from:
Drugs.com. Valporic acid. [Accessed 23 Apr. 2019] (online) Available from:
Sodium Valproate and Valproic Acid [Package Information]. Gangtok, Sikkim: TORRENT PHARMACEUTICALS LTD.; 2022. [Accessed 28th Sept. 2023] (online) Available from:
The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.