Trental 400 Tablet PR
Prescription Required
Product introduction
Trental 400 Tablet PR is used to treat peripheral vascular disease (poor circulation to the arms and legs) and intermittent claudication (pain on walking or at rest caused by poor circulation to the legs). It works by increasing the blood flow to the arms and legs.
Trental 400 Tablet PR medicine reduces cramping in the legs that occurs on walking in such patients. It also has beneficial effects in alcohol-related liver damage. Lifestyle modifications like smoking cessation and regular exercise can provide better results with this medicine.
It may cause headache, dizziness, dizziness, sleep disorder, and flushing as side effects. Patients taking this medicine should use caution while driving or operating machines.
Uses of Trental Tablet PR
- Peripheral vascular disease
- Intermittent claudication
Side effects of Trental Tablet PR
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Trental
- Bloating
- Diarrhea
- Flushing (sense of warmth in the face, ears, neck and trunk)
- Headache
- Heartburn
- Lightheadedness
- Nausea
- Stomach discomfort
- Vomiting
- Weakness
- Dizziness
- Sleep disorder
How to use Trental Tablet PR
Use it as advised by your doctor or check the label for directions before use. Trental 400 Tablet PR is to be taken with food.
How Trental Tablet PR works
Trental 400 Tablet PR is a peripheral vasodilator. It works by decreasing the thickness (viscosity) of blood, allowing it to pass more easily through the blood vessels. This effect is beneficial in peripheral vascular disease, where the blood vessels in the arms and legs are narrowed.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Trental 400 Tablet PR. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Trental 400 Tablet PR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Trental 400 Tablet PR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Trental 400 Tablet PR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Trental 400 Tablet PR should be used with caution in patients with kidney disease. Dose adjustment of Trental 400 Tablet PR may be needed. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Trental 400 Tablet PR in patients with liver disease. Please consult your doctor.
What if you forget to take Trental Tablet PR?
If you miss a dose of Trental 400 Tablet PR, skip it and continue with your normal schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
- Take it as per dose and duration suggested by your doctor.
- Do not drive or perform activities that require mental focus until you know how Trental 400 Tablet PR affects you.
- Your doctor may get regular blood tests done to monitor liver function while taking this medicine.
- Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
- Take it with food, preferably at the same time everyday to avoid missing a dose.
Fact Box
Chemical Class
Methylxanthine Derivative
Habit Forming
No
Therapeutic Class
CARDIAC
Action Class
Hemorrheologic Agents
Interaction with drugs
Taking Trental with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concurrent use may cause severe headaches. Ciprofloxacin may raise blood levels of Pentoxifylline.
If concurrent use is essential, your doctor may monitor your treatment and adjust
Concurrent use may increase the risk of bleeding.
If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.
Pentoxifylline may raise blood levels of Aminophylline.
Do not consume Aminophylline with Pentoxifylline. If concurrent use is essential, watch out for symptoms such as nausea, pa
Concurrent use may cause severe headaches. Ciprofloxacin may raise blood levels of Pentoxifylline.
If concurrent use is essential, your doctor may monitor your treatment and adjust
Pentoxifylline may raise blood levels of Aminophylline.
Do not consume Aminophylline with Pentoxifylline. If concurrent use is essential, watch out for symptoms such as nausea, pa
Patient concerns
User feedback
Patients taking Trental 400 Tablet PR
Twice A Day
80%
Once A Day
20%
What are you using Trental Tablet PR for?
Peripheral va*
58%
Intermittent *
21%
Others
21%
*Peripheral vascular disease, Intermittent claudication
How much was the improvement?
Average
40%
Poor
32%
Excellent
28%
What were the side-effects while using Trental 400 Tablet PR?
No Side Effec*
48%
Nausea
20%
Agitation
8%
Diarrhea
4%
Bloating
4%
*No Side Effect
How do you take Trental Tablet PR?
With food
95%
With or witho*
5%
*With or without food
Please rate Trental 400 Tablet PR on price
Average
46%
Expensive
30%
Not Expensive
24%
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Katzung BG, Chatterjee K. Vasodilator & the Treatment of Angina Pectoris. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 205.
- Gersh BJ, Opie LH. Which Therapy for Which Condition? In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. p. 528.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1089-90.
- Pentoxifylline. Guildford, Surrey: SANOFI; 2002 [revised 25 May 2016]. [Accessed 25 Jan. 2019] (online) Available from:
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Pentoxifylline. [Updated 2018 Oct 31]. [Accessed 19 Feb. 2020] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:
- Pentoxifylline [Patient Information Leaflet]. Ankleshwar: Gujarat: Sanofi India Limited; 2015. [Accessed 06 Apr. 2024] (online) Available from:
Marketer details
Name: Sanofi India Ltd
Address: Sanofi House, CTS No.117-B, L&T Business Park, Saki Vihar Road, Powai, Mumbai 400072
Country of origin: India
Expires on or after: May, 2026
A licensed vendor partner from your nearest location will deliver Trental 400 Tablet PR. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Expires on or after: May, 2026
A licensed vendor partner from your nearest location will deliver Trental 400 Tablet PR. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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