Trexosafe M 500mg/250mg Tablet is a combination medicine used to treat heavy menstrual bleeding and menstrual pain. It prevents the breakdown of blood clots to control excessive bleeding during periods. It also blocks the production of certain chemical messengers that cause pain and inflammation.

You can take Trexosafe M 500mg/250mg Tablet at any time of day, with food, but it is best to take it at the same time each day. It should be taken on first day of the periods to get the most benefit. Keep taking it for as long as advised by your doctor. Take this medicine in the dose and duration advised by the doctor and if you have missed a dose, take it as soon as you remember. Remember to finish the full course of treatment even if you feel better. Inform your doctor if you do not observe any change in periods even after 3 consecutive periods.

The most common side effects of this medicine include nausea, stomach pain, headache, nasal congestion, sinus pain, sinus inflammation, rash, tiredness, and musculoskeletal (bone, muscle or joint) pain. It may also cause diarrhea, so it is better to take plenty of fluids while taking this medicine as it may help to prevent dehydration. It is advised to consult with your doctor if you do not notice any changes in periods after 3 consecutive periods.

Before taking it, let your doctor know if you have any kidney problems or vaginal bleeding disorder. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. You also need to tell your doctor what other medicines you are taking. You might be asked for eye check-ups while taking this medicine. It is advised to avoid alcohol while taking this medicine.

Uses of Trexosafe M Tablet

Treatment of Menstrual pain
Treatment of Heavy menstrual bleeding

Benefits of Trexosafe M Tablet

In Treatment of Menstrual pain

Trexosafe M 500mg/250mg Tablet relieves the pain due to muscle cramps during menstrual cycles (periods). It blocks the pain signals, relaxes the muscles and prevents sudden contractions (spasms) of muscles. This treats your pain and discomfort. You may also use a heating pad, take a hot water shower, avoid stress and try mild exercise for easing out the pain.

In Treatment of Heavy menstrual bleeding

Heavy menstrual bleeding is definitely a concern for every woman. Trexosafe M 500mg/250mg Tablet is a combination of medicine that helps treat heavy menstrual bleeding. It helps the lining of the uterus or womb to clot during periods and thus reduces heavy bleeding. It is advisable to use the medicine as prescribed for it to be effective. Also, you can do yoga or meditation to reduce stress and divert your mind during those days.

show less

Side effects of Trexosafe M Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Trexosafe M

Nausea
Vomiting
Heartburn
Indigestion
Diarrhea
Loss of appetite
Nasal congestion (stuffy nose)
Headache
Tiredness
Musculoskeletal (bone, muscle or joint) pain
Anemia (low number of red blood cells)
Stomach pain
Sinus pain
Sinus inflammation

How to use Trexosafe M Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Trexosafe M 500mg/250mg Tablet is to be taken with food.

How Trexosafe M Tablet works

Trexosafe M 500mg/250mg Tablet is a combination of two medicines: Tranexamic Acid and Mefenamic Acid. Tranexamic Acid is an anti-fibrinolytic. It works by preventing the breakdown of blood clots to control excessive bleeding during periods. Mefenamic Acid is a non-steroidal anti-inflammatory drug (NSAID) which blocks the production of certain chemical messengers (prostaglandins) that cause pain and inflammation (redness and swelling).

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Trexosafe M 500mg/250mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Trexosafe M 500mg/250mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Trexosafe M 500mg/250mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

UNSAFE

Trexosafe M 500mg/250mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Trexosafe M 500mg/250mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Trexosafe M 500mg/250mg Tablet may be needed. Please consult your doctor.
Use of Trexosafe M 500mg/250mg Tablet is not recommended in patients with severe kidney disease.

Liver

SAFE IF PRESCRIBED

Trexosafe M 500mg/250mg Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Trexosafe M 500mg/250mg Tablet may not be needed in these patients. Please consult your doctor.

What if you forget to take Trexosafe M Tablet?

If you miss a dose of Trexosafe M 500mg/250mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Trexosafe M 500mg/250mg Tablet

₹17.4/Tablet

Tenacid MF Tablet

Leeford Healthcare Ltd

₹14.6/tablet

16% cheaper

Redotrex MF 500mg/250mg Tablet

Leeford Healthcare Ltd

₹14.6/tablet

16% cheaper

Pause-MF Tablet

Emcure Pharmaceuticals Ltd

₹49.9/tablet

187% costlier

Trapic MF Tablet

Sun Pharmaceutical Industries Ltd

₹46.7/tablet

168% costlier

Trenaxa MF Tablet

Macleods Pharmaceuticals Pvt Ltd

₹52.17/tablet

200% costlier

View all substitutes

Quick tips

Trexosafe M 500mg/250mg Tablet helps relieve menstrual pain and abnormally heavy menstrual bleeding.
Your doctor will prescribe the lowest effective dose for the shortest possible time necessary to relieve your symptoms.
Take it with food to avoid an upset stomach.
Take it on the first day of a heavy period. Taking it before or after will not have any benefit.
Inform your doctor if there is no improvement in your bleeding after using this medicine for three consecutive menstrual periods.
Inform your doctor if you have a history of kidney or liver disease.

Fact Box

Habit Forming

Therapeutic Class

BLOOD RELATED

Patient concerns

Suddenly heavy menstrual bleeding

Dr. Megha Tuli

Obstetrics and Gynaecology

Tablet tranexa 500mg thrice a fay

I want to know about copper t is it safe to use for upto 2 years and does it have any side effects, is it possible copper t could be broken themselves

Dr. Jyoti Arora

Sexology

Copper-T is safe as a method of contraception but in some cases it causes heavy bleeding during menstrual cycle.If you have pain in the lower abdomen and heavy bleeding during your cycles then you should get yourself checked by a gynaecologist

FAQs

What is Trexosafe M 500mg/250mg Tablet?

Trexosafe M 500mg/250mg Tablet is a combination of two medicines: Tranexamic Acid and Mefenamic Acid. This medication is used to treat pain and is used to treat heavy bleeding during menstrual cycle (monthly periods) in women.

Are there any specific contraindications associated with the use of Trexosafe M 500mg/250mg Tablet?

Yes, it is considered to be harmful for patients with severe kidney failure, active intravascular clotting (obstruction in the blood flow due to blood clots), and color vision disorders.

What is the recommended storage condition for Trexosafe M 500mg/250mg Tablet?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Related ayurvedic ingredients

Fish Oil

Celery

LAVENDER

Top Cardiologists

Dr. Manjinder Sandhu

MBBS, MD, DNB, DM, Fellowship, Fellowship

4.7 ★

Dr. R. R. Kasliwal

MBBS, MD, DM, Fellowship

4.7 ★

Dr. Dhananjay Kumar Jhamb

MBBS, MD, DM

4.7 ★

Dr. Monik Mehta

MBBS, MD, DM, Fellowship

4.5 ★

Dr. (Col.) Balbir Kalra

MBBS, MD, DM

4.7 ★

Want to share the information?

Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Mefenamic acid. Egham, Surrey: Chemidex Pharma Ltd.; 2005 [revised 7 Dec. 2015]. [Accessed 10 Apr. 2019] (online) Available from:
Medscape. Tranexamic acid. [Accessed 10 Apr. 2019] (online) Available from:
Tranexamic Acid and Mefenamic Acid [Patient Information Sheet]. Ahmendabad, Gujarat: Torrent Pharaceuticals Ltd.; 2019. [Accessed 16 Sep. 2024] (online) Available from:

Marketer details

Name: Bioxtreme Pharma

Address: 315, Industrial Area, Phase-II, Panchkula, Haryana-134109

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.