Trigil 25 Tablet DT
Prescription Required
Product introduction
Trigil 25 Tablet DT is an anti-epileptic medication that is used to treat two conditions, epilepsy and bipolar disorder. It works by blocking the signals in the brain that trigger epileptic seizures (fits) and in another way to prevent extreme mood swings.
Trigil 25 Tablet DT can be used alone or in combination with other medicines. It may be taken with or without food. Your doctor will decide the correct dose for you. This may increase gradually until your condition is stable. This medicine may take several weeks to work but it is important to take it regularly to get the maximum benefit. Do not stop taking it, even if you feel fine unless your doctor advises you to. You may have more seizures, or your bipolar disorder may get worse.
The most common side effects of this medicine include skin rashes, headache, nausea, and vomiting, difficulty sleeping, and dizziness. Most side effects wear off, but if they bother you or do not go away, tell your doctor. Inform your doctor immediately if you notice a rash or peeling of the skin. There may be ways of preventing or reducing these effects. Long-term treatment can cause weakness in your bones (osteoporosis), increasing your risk of breaking a bone.
Before taking this medicine, tell your doctor if you have kidney or liver problems, depression, or suicidal thoughts. Also let your healthcare professional know about all other medications you are using as some may affect, or be affected by, this medicine, including contraceptive pills. Consult your doctor if you are pregnant or breastfeeding as the dose may need to be adjusted. You should avoid driving or anything that requires concentration if this medicine makes you drowsy or dizzy. You may need frequent blood tests to check how you are responding to this medicine.
Trigil 25 Tablet DT can be used alone or in combination with other medicines. It may be taken with or without food. Your doctor will decide the correct dose for you. This may increase gradually until your condition is stable. This medicine may take several weeks to work but it is important to take it regularly to get the maximum benefit. Do not stop taking it, even if you feel fine unless your doctor advises you to. You may have more seizures, or your bipolar disorder may get worse.
The most common side effects of this medicine include skin rashes, headache, nausea, and vomiting, difficulty sleeping, and dizziness. Most side effects wear off, but if they bother you or do not go away, tell your doctor. Inform your doctor immediately if you notice a rash or peeling of the skin. There may be ways of preventing or reducing these effects. Long-term treatment can cause weakness in your bones (osteoporosis), increasing your risk of breaking a bone.
Before taking this medicine, tell your doctor if you have kidney or liver problems, depression, or suicidal thoughts. Also let your healthcare professional know about all other medications you are using as some may affect, or be affected by, this medicine, including contraceptive pills. Consult your doctor if you are pregnant or breastfeeding as the dose may need to be adjusted. You should avoid driving or anything that requires concentration if this medicine makes you drowsy or dizzy. You may need frequent blood tests to check how you are responding to this medicine.
Uses of Trigil Tablet DT
Benefits of Trigil Tablet DT
In Epilepsy/Seizures
Trigil 25 Tablet DT is used alone or with other medicines to prevent and control seizures (fits). It works by decreasing the nerve impulses that cause seizures. It can help reduce symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety. By controlling the frequency of seizures, it will help you go about your daily activities with more confidence. It may also allow you to do some activities that you would otherwise be forbidden or scared to do (such as swimming and driving). This medicine may take several weeks or months to work effectively as the dose is adjusted. Carefully follow all instructions and never take more tablets than your doctor tells you to. It needs to be taken regularly as prescribed to be most effective.
In Bipolar disorder
Trigil 25 Tablet DT works to restore the normal balance of nerve activity in your brain. It is sometimes called a mood stabilizer and can help prevent extreme changes in mood and help you feel less agitated. You may experience fewer episodes of depression and low mood. It can take several weeks for this medicine to work and you may still feel low during this time. It is likely that you will take this medicine for at least six months but possibly much longer. It needs to be taken regularly to work effectively. Do not stop taking it unless your doctor advises you to. You should continue to eat well and keep fit to reduce symptoms of bipolar disorder.
Side effects of Trigil Tablet DT
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Trigil
- Skin rash
- Headache
- Nausea
- Vomiting
- Dryness in mouth
- Insomnia (difficulty in sleeping)
- Sleepiness
- Dizziness
- Back pain
- Abdominal pain
- Blurred vision
- Double vision
- Impaired coordination
- Nasal congestion (stuffy nose)
- Infection
How to use Trigil Tablet DT
Take this medicine in the dose and duration as advised by your doctor. Dissolve it in a glass of water before taking it. Trigil 25 Tablet DT may be taken with or without food, but it is better to take it at a fixed time.
How Trigil Tablet DT works
Trigil 25 Tablet DT is an antiepileptic medication. It controls seizures or fits by decreasing the abnormal and excessive activity of the nerve cells in the brain.
Safety advice
Alcohol
UNSAFE
Trigil 25 Tablet DT may cause excessive drowsiness with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
Trigil 25 Tablet DT may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Trigil 25 Tablet DT is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Monitor the baby for rash, sleepiness or poor sucking. Also, get the platelet count and liver function test done periodically.
Monitor the baby for rash, sleepiness or poor sucking. Also, get the platelet count and liver function test done periodically.
Driving
UNSAFE
Trigil 25 Tablet DT may cause side effects which could affect your ability to drive.
Trigil 25 Tablet DT can cause dizziness and double vision. This may affect your ability to drive.
Trigil 25 Tablet DT can cause dizziness and double vision. This may affect your ability to drive.
Kidney
CAUTION
Trigil 25 Tablet DT should be used with caution in patients with kidney disease. Dose adjustment of Trigil 25 Tablet DT may be needed. Please consult your doctor.
Liver
CAUTION
Trigil 25 Tablet DT should be used with caution in patients with liver disease. Dose adjustment of Trigil 25 Tablet DT may be needed. Please consult your doctor.
What if you forget to take Trigil Tablet DT?
If you miss a dose of Trigil 25 Tablet DT, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
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Quick tips
- Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
- Make sure that you have sufficient amount of medicine present with you.
- Some healthy tips to prevent seizures:
- Practice yoga every day.
- Get enough sleep at nighttime.
- Limit the use of screen time such as mobile/laptop.
- Take your medication on time.
- It may cause headaches. Drink plenty of water and take a suitable pain killer. Inform your doctor if it does not go away.
- It may cause skin rash. Inform your doctor immediately if you notice a rash, itching and peeling of skin.
- Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
- Do not stop taking the medication suddenly without talking to your doctor as it may increase the frequency of seizure.
- Trigil 25 Tablet DT helps in the treatment and prevention of seizures.
- Take it at the same time every day to maintain consistent levels in your body.
- It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
- Avoid consuming alcohol when taking Trigil 25 Tablet DT, as it may cause excessive sleepiness or drowsiness.
- Monitor your weight during treatment with this medicine as it can cause weight gain.
- Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
- Do not take Trigil 25 Tablet DT if you are pregnant or planning to conceive or breastfeeding.
- Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.
- Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
- Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
- Some healthy tips to prevent seizures:
- Practice yoga every day.
- Get enough sleep at nighttime.
- Limit the use of screen time such as mobile/laptop.
- Take your medication on time.
- It may increase the risk of low sodium levels in the blood. Inform your doctor if you develop difficulty concentrating, memory problems, confusion, weakness, and unsteadiness.
- Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
Fact Box
Chemical Class
Phenyltriazine Derivative
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Sodium Channel Modulators- Antiepileptic drugs (AEDs)
Interaction with drugs
Taking Trigil with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Progesterone may reduce blood levels of Lamotrigine.
Do not consume Progesterone with Lamotrigine. If concurrent use is essential, please consult your doctor.
Progesterone (Natural Micronized) may reduce blood levels of Lamotrigine.
Do not consume Progesterone (Natural Micronized) with Lamotrigine. If concurrent use is essential, please
Lamotrigine may raise blood levels of active form of Carbamazepine. Carbamazepine may reduce blood levels of Lamotrigine.
Please inform your doctor if you experience nausea, vomiti
Concurrent use may cause sedation, tremors, poor muscle control, fatigue, and rash. Sodium Valproate may raise blood levels of Lamotrigine.
If concurrent use is essential, your doc
Estradiol may reduce blood levels of Lamotrigine.
Do not consume Estradiol with Lamotrigine. If concurrent use is essential, please consult your doctor.
Patient concerns
FAQs
I started Trigil 25 Tablet DT and developed a rash. The doctor stopped Trigil 25 Tablet DT immediately and prescribed another medicine. Why?
There have been reports where patients developed serious rashes within 8 weeks of starting Trigil 25 Tablet DT and were hospitalized. Sometimes these rashes turn into severe skin infections and may endanger the patient’s life. Therefore, it is advised that if a patient develops rashes after starting Trigil 25 Tablet DT, it should be stopped and should not be restarted. Use of Trigil 25 Tablet DT is stopped even if the rashes are mild and non-serious. It is because of this that your doctor changed the medicine.
How long does it take Trigil 25 Tablet DT to work?
Though it varies from person to person, your symptoms may take about 6-8 weeks to improve.
What can be the consequences of taking a higher than the recommended dose of Trigil 25 Tablet DT?
You may experience quick and uncontrollable movements of your eye, clumsiness, and lack of coordination. High doses of Trigil 25 Tablet DT may cause problems with your balance, changes in heartbeat rhythm, loss of consciousness, fits (convulsions) or coma. Even if there are no signs of discomfort, seek immediate medical attention of a doctor or nearby hospital.
Can Trigil 25 Tablet DT affect pregnancy?
Studies on the human population do not show any effects of Trigil 25 Tablet DT on pregnant women or her fetus. However, it is advisable that you inform your doctor immediately if you become pregnant or are planning to get pregnant while taking Trigil 25 Tablet DT. In case therapy with Trigil 25 Tablet DT is considered during pregnancy, your doctor may prescribe the lowest effective dose.
Can I take Trigil 25 Tablet DT with other antiepileptic medicines?
It is important that you inform your doctor if you are already on any other antiepileptic medicines. The reason being, taking Trigil 25 Tablet DT with some antiepileptics (like valproate and carbamazepine) may increase the chances of developing side effects. Also, the dose of Trigil 25 Tablet DT may need adjustment if taken with antiepileptic medicines such as oxcarbazepine, felbamate, gabapentin, levetiracetam, pregabalin, topiramate or zonisamide.
How to take Trigil 25 Tablet DT?
Trigil 25 Tablet DT can be taken with or without food. Continue taking Trigil 25 Tablet DT in the dose and duration advised by the doctor to get maximum benefits of Trigil 25 Tablet DT.
I have symptoms of depression. Can I take Trigil 25 Tablet DT?
Yes, you can take Trigil 25 Tablet DT if you have depression symptoms. In fact, Trigil 25 Tablet DT is used in preventing depression. But, do not self medicate. Do not start or stop taking Trigil 25 Tablet DT on your own, unless otherwise advised by the doctor.
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Stahl SM, editor. Lamotrigine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 325-32.
- McNamara JO. Pharmacotherapy of the Epilepsies. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 599-600.
- Porters RJ, Meldrum BS. Antiseizure Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 409.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 771-74.
- Lamotrigine. Uxbridge, Middlesex: GlaxoSmithKline UK; 1991 [revised 24 Oct. 2018]. [Accessed 23 Jan. 2019] (online) Available from:
- Lamotrigine. Greenville, NC: GlaxoSmithKline; 2009. [Accessed 25 Mar. 2019] (online) Available from:
- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 20 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:
- Lamotrigine [Package Insert]. Gangtok, Sikkim: Torrent Pharmaceuticals Ltd.; 2021. [Accessed 08 Jul. 2023]. (online) Available from:
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Country of origin: India
The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.
The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.
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