Trinerve Forte Capsule is used to treat neuropathic pain. It decreases the pain by controlling calcium channel activity and by decreasing the production of a substance that protects nerve fibers and rejuvenates damaged nerve cells.
Trinerve Forte Capsule can be taken on empty stomach. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important not to stop taking this medicine suddenly without talking to the doctor.
Common side effects of this medicine include dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. It may also cause nasopharyngitis, increased appetite, confusion, difficulty in sleeping, decreased libido, tremor, vision blurred, and vertigo. Inform your doctor if you develop any unusual changes in the mood or behavior, new or worsening depression, or suicidal thoughts. It is better to avoid alcohol while taking this medicine as it can enhance the dizziness effect of the drug.
Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Trinerve
Dizziness
Sleepiness
Tiredness
Uncoordinated body movements
Nasopharyngitis (inflammation of the throat and nasal passages)
Increased appetite
Confusion
Insomnia (difficulty in sleeping)
Decreased libido
Tremors
Vertigo
Blurred vision
How to use Trinerve Capsule
Take this medicine in the dose and duration as advised by your doctor. Trinerve Forte Capsule is to be taken empty stomach.
How Trinerve Capsule works
Trinerve Forte Capsule is a combination of five medicines: Alpha Lipoic Acid, Folic Acid, Methylcobalamin, Pregabalin and Vitamin B6 (Pyridoxine). Alpha Lipoic Acid is a naturally occurring fatty acid which has a protective effect on the brain and nerve tissues. Folic Acid provides essential nutrients to the nerves. Methylcobalamin and Vitamin B6 (Pyridoxine) are forms of vitamin B which help in the production of myelin, a substance that protects nerve fibers and rejuvenates damaged nerve cells. Pregabalin is an alpha 2 delta ligand which decreases pain by modulating calcium channel activity of the nerve cells. Together, they relieve neuropathic pain (pain from damaged nerves).
Safety advice
Alcohol
CAUTION
Caution is advised when consuming alcohol with Trinerve Forte Capsule. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Trinerve Forte Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Trinerve Forte Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Trinerve Forte Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Trinerve Forte Capsule is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Trinerve Forte Capsule may not be needed in these patients. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Trinerve Forte Capsule is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Trinerve Forte Capsule may not be needed in these patients. Please consult your doctor.
What if you forget to take Trinerve Capsule?
If you miss a dose of Trinerve Forte Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Trinerve Forte Capsule helps treat nerve pain caused by diabetes, shingles or an injury.
Its side effects are usually mild and go away by themselves.
It may cause sleepiness. Don't drive or do anything requiring concentration until you know how it affects you.
Avoid consuming alcohol when taking this medicine, as it may cause excessive sleepiness or drowsiness.
Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
Do not stop taking the medication suddenly without talking to your doctor.
Fact Box
Habit Forming
No
Therapeutic Class
NEURO CNS
Patient concerns
Dr prescribed me to take Trinerve for Bells Palsys. I find Trinerve to have three variants Trinerve Forte Capsule, Trinerve LC Tablet and Trinerve Softgelatine capsule. Which one does Trinerve mean?
Dr. Sunil Sekhri
Diabetology
I can not comment on this because I do not prescribe this medicine for my patient s with Bells Palsy. Please contact your treating docotr
Sir Plz suggest me effective pain killer with minimum side effects for back pain and arthritis, which can be taken on regular basis as and when required.
Dr. Vikas Sharma
Neurology
dpeneds on the type of pain - muscular or neuropathic; show tro nearby neuro
Burning sensation in sole ,penile region regularly No spot at penile area but constant burning sensation at sole and penile area No relief from amoxicillin,ceprofloxin doxycyclene Period :last 14 days
Dr. Pranay Gandhi
Sexology
that may be a neuropathic pain. do u have high bp or diabetes. take tablet pregama m 1 od for 15 days
Sir I have pain in my right hand upper in elbow muscle it get hard some time and pain lot it happen since 4 month some of tell that nerves get hard that why it pain.sir plz suggest me what to do. I have taken medicine like gabapain nt; zerodol,Trinerve,vetory sp ,switch 200 but their is no any releaf sir
I suffered from brain stroke. How long can I use gabapentin 300 mg tablets ?
Dr. Anshul Varshney
Physician
Hello, Welcome to 1mg. I am Anshul Varshney for your help. This medicine is used to calm down the neuropathic pain. You may take it till you feel better. Later your doctor may reduce the dose and stop it.
What were the side-effects while using Trinerve Forte Capsule?
No Side Effec*
27%
Dizziness
27%
Sleepiness
18%
Drowsiness
9%
Uncoordinated*
9%
*No Side Effect, Uncoordinated body movements
How do you take Trinerve Capsule?
With food
89%
Empty stomach
11%
Please rate Trinerve Forte Capsule on price
Expensive
52%
Average
37%
Not Expensive
11%
FAQs
Q. What is Trinerve Forte Capsule?
Trinerve Forte Capsule is a combination of five medicines: Pregabalin, Methylcobalamin, Folic acid, Alpha lipoic acid, and Vitamin B6. This medicine is useful in the treatment of nerve pain (neuropathic pain). This medicine calms the damaged or overactive nerves by acting on the brain, thereby decreasing the pain sensation. It also helps in the regeneration of damaged nerves in the body.
Q. Can I stop taking Trinerve Forte Capsule when my pain is relieved?
No, you should not stop taking Trinerve Forte Capsule even if your pain is relieved. Continue to take it as advised by your doctor. If you suddenly stop taking Trinerve Forte Capsule, you may experience withdrawal symptoms such as anxiety, sleeping difficulties, nausea, pain and sweating. You may need to gradually taper the use of Trinerve Forte Capsule before you stop the medication completely.
Q. How to manage weight gain associated with the use of Trinerve Forte Capsule?
Trinerve Forte Capsule can make you feel hungry which might make you eat more, thereby increasing your chances of putting on weight. However, preventing weight gain is easier than losing the increased weight. Try to eat a healthy balanced diet without increasing your portion sizes (per-meal intake). Do not eat food items that contain a lot of calories, such as soft drinks, oily food, chips, cakes, biscuits and sweets. If you feel hungry between meals, avoid eating junk food and eat fruits, vegetables and low-calorie foods. Regular exercise will help prevent weight gain. If you maintain good eating habits and exercise regularly, you might not gain any weight.
Q. Can the use of Trinerve Forte Capsule cause sleepiness or drowsiness?
Yes, Trinerve Forte Capsule may make you feel drowsy or you may suddenly fall asleep during your daily activities. Sometimes, you might not even feel drowsy or have any other warning signs before you suddenly fall asleep. Avoid driving a car, operating machinery, working at heights or participating in potentially dangerous activities until you know how the medicine affects you. Inform your doctor if you experience such episodes while you are taking this medicine.
Q. Are there any serious side effects associated with the use of Trinerve Forte Capsule?
Serious side effects because of Trinerve Forte Capsule are uncommon and rare. However, it may cause serious side effects like an allergic reaction, suicidal thoughts or swelling of limbs (hands, legs or feet). Stop taking Trinerve Forte Capsule and contact your health care provider if you have any signs of these serious side effects. Signs of allergic reaction include swelling of your face, mouth, lips, gums, tongue and neck, trouble in breathing, skin rash, hives (raised bumps) or blisters. Pay attention to sudden changes in mood, behaviors, thoughts, or feelings as these may be a symptom of suicidal thoughts.
Q. How long will Trinerve Forte Capsule take to act?
An initial benefit with Trinerve Forte Capsule may be seen after 2 weeks of treatment. However, it may take around 2-3 months to see the full benefit. It may take longer in some patients.
Q. What if I forget to take Trinerve Forte Capsule?
If you forget to take the scheduled dose of Trinerve Forte Capsule and it is almost time for your next dose, skip the dose you missed and take your next dose at the scheduled time. Otherwise, take it as soon as you remember, and then go back to taking your medicine as you would normally. Do not take a double dose to make up for the dose you missed because this may increase the risk of unwanted side effects. If you are not sure what to do, consult your doctor about how to manage a situation like this.
Q. What if I take too much of this drug by mistake?
In a situation like this, contact your doctor immediately or seek emergency help at the nearest hospital. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention. Symptoms of an overdose may include drowsiness, weakness, unsteadiness while walking, having double visions, slurred speech or diarrhea, confusion, blurred vision, dizziness, body temperature changes (low and high), difficulty in breathing and increased heartbeat.
Q. Will a higher than the recommended dose of Trinerve Forte Capsule be more effective?
No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having some serious side effects and toxicity. If you experience increased severity of your symptoms, that are not relieved by the recommended doses, please consult your doctor for re-evaluation.
Q. Can I drink alcohol while taking Trinerve Forte Capsule?
No, do not drink alcohol while you are taking Trinerve Forte Capsule. Drinking alcohol can increase the severity of drowsiness or sleepiness caused by Trinerve Forte Capsule.
Q. How often should I see the doctor?
You may need to see your doctor regularly if you have started to take Trinerve Forte Capsule. However, consult your doctor if the recommended dosage does not improve your symptoms or you continue experiencing some unwanted side effect that affect your routine activities.
Q. What are the instructions for the storage and disposal of Trinerve Forte Capsule?
Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
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References
MedlinePlus. Vitamin B12. [Accessed 22 Apr. 2019] (online) Available from:
Pregabalin. Vega Baja, Puerto Rico: Pfizer Pharmaceuticals LLC; 2009. [Accessed 22 Apr. 2019] (online) Available from:
Mayo Clinic. Vitamin B-6. [Accessed 22 Apr. 2019] (online) Available from:
Pregabalin, Methylcobalamin, Alpha Lipoic Acid, Pyridoxine Hydrochloride and Folic Acid [Patient Information Sheet]. Solan, HP: Innova Captab Ltd.; 2021. [Accessed 14 Aug. 2024] (online) Available from: